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Journal Article
Nature Communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 797 - 18
Journal Article
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, ISSN 1756-9966, 07/2019, Volume 38, Issue 1, pp. 309 - 309
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 05/2016, Volume 55, Issue 5, pp. 688 - 704
The apurinic/apyrimidinic endonuclease 1 (APE1) is a protein central to the base excision DNA repair pathway and operates in the modulation of gene expression... 
combination therapy | NPM1 | small molecule | protein/protein interaction | APE1 | Protein/protein interaction | Small molecule | Combination therapy | APE1/REF-1 | CRITICAL LYSINE RESIDUES | protein interaction | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | HEPATOCELLULAR-CARCINOMA | PROTEIN INTERACTIONS | NUCLEOPHOSMIN | ONCOLOGY | protein | N-TERMINAL DOMAIN | DNA-REPAIR | EXPRESSION | Neoplasms - metabolism | Cell Survival - drug effects | Small Molecule Libraries - pharmacology | Humans | Nuclear Proteins - metabolism | High-Throughput Screening Assays | DNA-(Apurinic or Apyrimidinic Site) Lyase - metabolism | MCF-7 Cells | Nuclear Proteins - antagonists & inhibitors | Protein Binding - drug effects | Cell Line, Tumor | Female | Antineoplastic Agents - pharmacology | Cell Proliferation - drug effects | DNA-(Apurinic or Apyrimidinic Site) Lyase - antagonists & inhibitors | HeLa Cells | Neoplasms - pathology | Proteins | Chemotherapy | Pharmacology | DNA repair | Tumors | Cell proliferation | Drugs | Surgical implants | Ovarian carcinoma | Liver | High-throughput screening | Genomes | Drug development | Assaying | Ovarian cancer | Anticancer properties | Biomedical materials | Antitumor agents | Bioactive compounds | Modulation | Biocompatibility | Localization | Deoxyribonucleic acid--DNA | Cell survival | Aggressive behavior | Preservation | Maturation | Tumor cells | rRNA | Light emitting diodes | Chemiluminescence | Gene expression | Screening | Inhibitors | Medical prognosis | Cells (biology) | Aberration | Position (location) | Protein interaction | Endonuclease | Cancer | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, pp. e0186615 - e0186615
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and fatal disease. Histone deacetylase 6 (HDAC6) alters function and fate of various... 
EPITHELIAL-MESENCHYMAL TRANSITION | LUNG FIBROSIS | IN-VITRO | TGF-BETA | HISTONE DEACETYLASE INHIBITION | MULTIDISCIPLINARY SCIENCES | TUBULIN ACETYLATION | DISEASE | AUTOPHAGY | MYOFIBROBLAST DIFFERENTIATION | EXPRESSION | Idiopathic Pulmonary Fibrosis - genetics | Ribosomal Protein S6 Kinases - metabolism | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Phosphoprotein Phosphatases - metabolism | Male | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | RNA, Messenger - metabolism | Autophagy - drug effects | Idiopathic Pulmonary Fibrosis - metabolism | Mechanistic Target of Rapamycin Complex 1 | Autophagosomes - drug effects | Multiprotein Complexes - metabolism | Tubulin - metabolism | Bleomycin | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Aged, 80 and over | Female | Indoles - pharmacology | Lung - metabolism | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Hydroxamic Acids - pharmacology | Fibroblasts - metabolism | Lung - pathology | Collagen Type I - metabolism | Histone Deacetylases - genetics | Histone Deacetylase 6 | RNA, Messenger - genetics | Histone Deacetylases - metabolism | Nuclear Proteins - metabolism | Autophagosomes - metabolism | Mice, Knockout | Transforming Growth Factor beta - pharmacology | Animals | Signal Transduction - drug effects | Fibroblasts - drug effects | Idiopathic Pulmonary Fibrosis - pathology | Hydroxamic Acids - therapeutic use | Indoles - therapeutic use | Aged | Transforming Growth Factor beta - metabolism | Idiopathic Pulmonary Fibrosis - drug therapy | Histone deacetylase | Deregulation | Collagen (type I) | Phosphorylation | Disease | Mesenchyme | Pathogenesis | Lung | Critical care | AKT protein | Leucine | Kinases | Autophagy | Proteins | Fibroblasts | Vascular endothelial growth factor | Internal medicine | Lung diseases | Environmental health | 1-Phosphatidylinositol 3-kinase | Medicine | Pulmonary fibrosis | Inhibitors | Lungs | Lysine | Deacetylation | Collagen | Fibrosis | Mice | Protein phosphatase | Phagocytosis | Index Medicus
Journal Article