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by McKay, J.D and Hung, R.J and Han, Y and Zong, X and Carreras-Torres, R and Christiani, D.C and Caporaso, N and Johansson, M and Li, Y and Byun, J.Y and Dunning, A and Pooley, K.A and Qian, D.C and Liu, G and Bojesen, S.E and Wu, X and Marchand, L. le and Albanes, D and Bickeböller, H and Alich, M.C and Bush, W.S and Tardon, A and Rennert, G and Teare, M.D and Field, J.K and Kiemeney, L.A and Lazarus, P and Haugen, A and Schabath, M.B and Anew, A.S and Shen, H and Hong, Y.C and Yuan, J.M and Bertazzi, P.A and Pesatori, A.C and Ye, Y and Diao, N and Su, L and Zhang, R and Brhane, Y and Leighl, N and Johansen, J.S and Mellemgaard, A and Saliba, W and Haiman, C.A and Wilkens, L.R and Fernandez-Somoano, A and Fernandez-Tardon, G and Heijden, H.F.M. van der and Kim, J.H and Hu, Z and Davies, M and Brunnström, H and Manjer, J and Melander, O and Muller, D and Overvad, K and Trichopoulou, A and Tumino, R and Doherty, J.A and Barnett, M.P and Chen, C and Goodman, G.E and Cox, A and Taylor, F and Woll, P.J and Brüske, I and Wichmann, H.E and Manz, J and Muley, T.R and Risch, A and Rosenberger, A and Grankvist, K and Shepherd, F.A and Tsao, M.S and Haura, E.B and Bolca, C and Holcatova, I and Janout, V and Kontic, M and Lissowska, J and Mukeria, A and Ognjanovic, S and Orlowski, T.M and Scelo, G and Swiatkowska, B and Zaridze, D and Bakke, P and Skaug, V and Zienolddiny, S and Duell, E.J and Butler, L.M and Koh, W.P and Gao, Y.T and Houlston, R.S and McLaughlin, J and Stevens, V.L and Joubert, P and Lamontagne, M and Nickle, D.C and ... and SpiroMeta Consortium and Medicinska fakulteten and Institutionen för medicinsk biovetenskap and Institutionen för strålningsvetenskaper and Umeå universitet
Nature Genetics, ISSN 1061-4036, 2017, Volume 49, Issue 7, pp. 1126 - 1132
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 12/2012, Volume 303, Issue 12, pp. G1299 - G1311
Journal Article
Nature genetics, ISSN 1061-4036, 2010, Volume 42, Issue 4, pp. 332 - 337
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2014, Volume 46, Issue 10, pp. 1131 - 1134
Pancreatitis occurs in approximately 4% of patients treated with the thiopurines azathioprine or mercaptopurine. Its development is unpredictable and almost... 
AZATHIOPRINE | THERAPY | COMPLICATION | GENOTYPE | DISEASE | GENETICS & HEREDITY | Haplotypes | Humans | HLA-DQ alpha-Chains - chemistry | HLA-DQ alpha-Chains - genetics | Mercaptopurine - chemistry | Pancreatitis - genetics | Mercaptopurine - metabolism | Immunosuppressive Agents - metabolism | Molecular Structure | HLA-DRB1 Chains - metabolism | Inflammatory Bowel Diseases - drug therapy | Protein Structure, Tertiary | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Azathioprine - metabolism | HLA-DRB1 Chains - genetics | Gene Frequency | Risk Factors | Mercaptopurine - adverse effects | Models, Molecular | Genotype | Pancreatitis - chemically induced | Azathioprine - chemistry | Protein Binding | Immunosuppressive Agents - adverse effects | Polymorphism, Single Nucleotide | HLA-DRB1 Chains - chemistry | Azathioprine - adverse effects | HLA-DQ alpha-Chains - metabolism | Immunosuppressive Agents - chemistry | Complications and side effects | Pancreatitis | Genetic aspects | Histocompatibility | Health aspects | Risk factors | Immunosuppressive agents | Studies | Inflammatory bowel disease | Medical research | Genomes | Drug therapy | Methods | Crohns disease | Index Medicus | Genetik | Basic Medicine | Medical Genetics | Medicinsk genetik | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Genetics
Journal Article
Gut, ISSN 0017-5749, 01/2014, Volume 63, Issue 1, pp. 80 - 87
Objective Crohn's disease (CD) is an intractable inflammatory bowel disease (IBD) of unknown cause. Recent meta-analysis of the genome-wide association studies... 
PROTEIN | IBD - Genetics | VARIANTS | TNFSF15 | ULCERATIVE-COLITIS | AUTOPHAGY | CELL DEVELOPMENT | Genetic Polymorphisms | Linkage Disequilibrium | Crohn's Disease | INFLAMMATORY-BOWEL-DISEASE | POLYMORPHISMS | ATG16L1 | Inflammatory Bowel Disease | JAPANESE PATIENTS | GASTROENTEROLOGY & HEPATOLOGY | Crohn Disease - genetics | Autophagy-Related Proteins | Humans | Asian Continental Ancestry Group - genetics | Male | Genotyping Techniques | Crohn Disease - ethnology | Case-Control Studies | Young Adult | Dual-Specificity Phosphatases - genetics | Adult | Female | Odds Ratio | Republic of Korea | Genome-Wide Association Study | Membrane Proteins - genetics | RNA Splicing Factors | Logistic Models | Genetic Markers | Carrier Proteins - genetics | Adolescent | Genetic Predisposition to Disease - ethnology | Polymorphism, Single Nucleotide | GTPase-Activating Proteins - genetics | SMN Complex Proteins - genetics | Kruppel-Like Transcription Factors - genetics | Demographic aspects | Genetic susceptibility | Crohn's disease | Genetic aspects | Research | Koreans | Health aspects | Risk factors | Genes | Principal components analysis | Whites | Genomes | Crohns disease | Inflammatory bowel disease | Studies | Consortia | Quality control | Population | Genetics | Software | Chromosomes | Asians | Index Medicus | Abridged Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2013, Volume 45, Issue 7, pp. 808 - 812
Journal Article
Journal Article
by Voight, Benjamin and Scott, Laura and Steinthorsdottir, Valgerdur and Morris, Anew and Dina, Christian and Welch, Ryan and Zeggini, Eleftheria and Huth, Cornelia and Aulchenko, Yurii and Thorleifsson, Gudmar and McCulloch, Laura and Ferreira, Teresa and Grallert, Harald and Amin, Najaf and Wu, Guanming and Willer, Cristen and Raychaudhuri, Soumya and McCarroll, Steven and Langenberg, Claudia and Hofmann, Oliver and Dupuis, Josée and Qi, Lu and Segrè, Ayellet and Hoek, Mandy and Navarro, Pau and Ardlie, Kristin and Balkau, Beverley and Benediktsson, Rafn and Bennett, Amanda and Blagieva, Roza and Boerwinkle, Eric and Bonnycastle, Lori and Boström, Kristina Bengtsson and Bravenboer, Bert and Bumpstead, Suzannah and Burtt, Noël and Charpentier, Guillaume and Chines, Peter and Cornelis, Marilyn and Couper, David and Crawford, Gabe and Doney, Alex and Elliott, Katherine and Erdos, Michael and Fox, Caroline and Franklin, Christopher and Ganser, Martha and Gieger, Christian and Grarup, Niels and Green, Todd and Griffin, Simon and Groves, Christopher and Guiducci, Candace and Hadjadj, Samy and Hassanali, Neelam and Herder, Christian and Isomaa, Bo and Jackson, Anne and Johnson, Paul and Jørgensen, Torben and Kao, Wen and Klopp, Norman and Kong, Augustine and Kraft, Peter and Kuusisto, Johanna and Lauritzen, Torsten and Li, Man and Lieverse, Aloysius and Lindgren, Cecilia and Lyssenko, Valeriya and Marre, Michel and Meitinger, Thomas and Midthjell, Kristian and Morken, Mario and Narisu, Narisu and Nilsson, Peter and Owen, Katharine and Payne, Felicity and Perry, John and Petersen, A.K and Platou, Carl and Proença, Christine and Prokopenko, Inga and Rathmann, Wolfgang and Rayner, Nigel William and Robertson, Neil and Rocheleau, Ghislain and Roden, Michael and Sampson, Michael and Saxena, Richa and Shields, Beverley and Shrader, Peter and Sigurdsson, Gunnar and Sparsø, Thomas and Strassburger, Klaus and Stringham, Heather and Sun, Qi and Swift, Amy and Thorand, Barbara and Tichet, Jean and ... and GIANT Consortium and MAGIC Investigators and MAGIC investigators and The GIANT Consortium and The MAGIC investigators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Uppsala universitet
Nature Genetics, ISSN 1061-4036, 07/2010, Volume 42, Issue 7, pp. 579 - 589
Journal Article