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Should Trypanosoma cruzi be Called "cruzi" Complex? A Review of the Parasite Diversity and the Potential of Selecting Population after in Vitro Culturing and Mice Infection, 12/2003
Morpho-biological diversity of Trypanosoma cruzi has been known since Chagas' first works in 1909. Several further studies confirmed the morphological... 
Trypanosoma cruzi - "cruzi" complex - genetic diversity
Journal
Parasitism of adipocytes by Trypanosoma cruzi, 12/1995
Journal
Immunopathology of Chagas Disease, 12/1999
The main clinical forms of Chagas disease (acute, indeterminate and chronic cardiac) present strong evidences for the participation of the immune system on... 
Trypanosoma cruzi - immunopathology - myocarditis
Journal
The occurrence of Rhodnius prolixus Stal, 1859, naturally infected by Trypanosoma cruzi in the State of Rio de Janeiro, Brazil (Hemiptera, Reduviidae, Triatominae), 12/1998
Rhodnius prolixus, one of the most important vector of Chagas' disease in Venezuela, was basically considered in this country as related to the domiciliar... 
Trypanosoma cruzi - Rhodnius prolixus
Journal
RESEARCH NOTE - Isoenzymatic Characterization of Colombian Strains of Trypanosoma cruzi, 12/1998
Trypanosoma cruzi, the causative agent of Chagas' disease is a highly pleomorphic parasite with a complex life cycle involving both a vertebrate host and an... 
isoenzymes - Trypanosoma cruzi - variability
Journal
RESEARCH NOTE - Isoenzymatic Characterization of Colombian Strains of Trypanosoma cruzi, 12/1998
Trypanosoma cruzi, the causative agent of Chagas' disease is a highly pleomorphic parasite with a complex life cycle involving both a vertebrate host and an... 
isoenzymes - Trypanosoma cruzi - variability
Journal
Experimental Parasitology, ISSN 0014-4894, 2009, Volume 123, Issue 4, pp. 283 - 291
A multiplex PCR was developed for simultaneous detection of DNA and classification of the parasite strain into groups I and II. As little as 10 fg of DNA could... 
Molecular diagnosis | T. cruzi group | RAPD | ribosomal DNA | Trypanosoma cruzi group II | T cruzi II | kinetoplast deoxyribonucleic acid | Z2, Z3, zymodemes 1, 2, and 3 | restriction fragment length polymorphism | Triatoma infestans | deoxyribonucleic acid | random amplification of polymorphic DNA | kDNA | polymerase chain reaction | RFLP | PBS | Trypanosoma cruzi | Triatomine | Satellite DNA | Multiplex PCR | rDNA | DNA | phosphate buffered saline | Trypanosoma cruzi group I | T. cruzi I | PCR | CHAGAS-DISEASE | RFLP, restriction fragment length polymorphism | rDNA, ribosomal DNA | kDNA, kinetoplast deoxyribonucleic acid | DNA, deoxyribonucleic acid | REPETITIVE DNA | PARASITOLOGY | MIXED INFECTIONS | PHYLOGENETIC LINEAGES | PBS, phosphate buffered saline | T. cruzi I, Trypanosoma cruzi group I | RAPD, random amplification of polymorphic | Z1, Z2, Z3, zymodemes 1, 2, and 3 | SANTA-CATARINA | POLYMERASE-CHAIN-REACTION | SEQUENCE ALIGNMENT | PCR, polymerase chain reaction | T cruzi II, Trypanosoma cruzi group II | AMPLIFIED POLYMORPHIC DNA | TRIATOMINE BUGS | Chagas Disease - parasitology | DNA, Protozoan - isolation & purification | Humans | Trypanosoma cruzi - genetics | Molecular Sequence Data | Trypanosoma cruzi - isolation & purification | Phylogeny | Sequence Analysis, DNA | DNA, Protozoan - analysis | Polymerase Chain Reaction - methods | Animals | Trypanosoma cruzi - classification | Base Sequence | Sensitivity and Specificity | Chagas Disease - diagnosis | Repetitive Sequences, Nucleic Acid | Mice | DNA, Protozoan - chemistry | DNA, Satellite - chemistry | Polymerase chain reaction | Phosphates
Journal Article
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 11/2016, Volume 123, pp. 895 - 904
3-Nitro-1 -1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both and in an acute... 
Chagas disease | Type I nitroreductase | HAT disease | Leishmania | Nitrotriazoles | CHEMISTRY, MEDICINAL | ANTICHAGASIC AGENTS | NITROREDUCTASE | TRYPANOSOMA-CRUZI | CHAGAS-DISEASE | DISCOVERY | STEROL 14-ALPHA-DEMETHYLASE | PRODRUGS | IN-VIVO | VISCERAL LEISHMANIASIS | BENZNIDAZOLE | Trypanosomiasis, African - drug therapy | Triazoles - chemistry | Trypanosomiasis, African - metabolism | Acetamides - pharmacology | Trypanocidal Agents - chemistry | Structure-Activity Relationship | Trypanosoma cruzi - physiology | Acetamides - chemistry | Animals | Nitroreductases - metabolism | Acetamides - therapeutic use | Trypanocidal Agents - pharmacology | Trypanosoma cruzi - drug effects | Trypanocidal Agents - therapeutic use | Mice | Enzymes | Chemotherapy | Triazoles | Community colleges | Analysis | Cancer | Medicine, Experimental | Medical research | Chagas' disease | Cytochrome P-450 | www.who.int | T. cruzi, Trypanosoma cruzi | tdr | Bnz, benznidazole (N-benzyl-2-(2-nitro-1H-imidazol-1-yl)acetamide) | HAT, human African trypanosomiasis | SI, selectivity index | NTD, Neglected tropical diseases | TcNTR, T. cruzi NTR | Nfx, nifurtimox (4-(5-nitrofurfurylindenamino)-3-methylthio-morpholine-1,1-dioxide) | TcCYP51, T. cruzi CYP51 | TDR, Tropical Diseases Research (http | Research Paper | NTR, type I nitroreductase | CYP51, sterol 14α-demethylase enzyme | IC50, concentration for 50% growth inhibition | TbNTR, T. brucei NTR | T. brucei, Trypanosoma brucei | SAR, structure-activity relationships
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2735, 2011, Volume 5, Issue 1, p. e931
Journal Article
by Najib M. El-Sayed and Peter J. Myler and Daniella C. Bartholomeu and Daniel Nilsson and Gautam Aggarwal and Anh-Nhi Tran and Elodie Ghedin and Elizabeth A. Worthey and Arthur L. Delcher and Gaëlle Blandin and Scott J. Westenberger and Elisabet Caler and Gustavo C. Cerqueira and Carole Branched Brian Haas and Atashi Anupama and Erik Arner and Lena Åslund and Philip Attipoe and Esteban Bontempi and Frédéric Bringaud and Peter Burton and Eithon Cadag and David A. Campbell and Mark Carrington and Jonathan Crabtree and Hamid Darban and Jose Franco da Silveira and Pieter de Jong and Kimberly Edwards and Paul T. Englund and Gholam Fazelina and Tamara Feldblyum and Marcela Ferella and Alberto Carlos Frasch and Keith Gull and David Horn and Lihua Hou and Yiting Huang and Ellen Kindlund and Michele Klingbeil and Sindy Kluge and Hean Koo and Daniela Lacerda and Mariano J. Levin and Hernan Lorenzi and Tin Louie and Carlos Renato Machado and Richard McCulloch and Alan McKenna and Yumi Mizuno and Jeremy C. Mottram and Siri Nelson and Stephen Ochaya and Kazutoyo Osoegawa and Grace Pai and Marilyn Parsons and Martin Pentony and Ulf Pettersson and Mihai Pop and Jose Luis Ramirez and Joel Rinta and Laura Robertson and Steven L. Salzberg and Daniel O. Sanchez and Amber Seyler and Reuben Sharma and Jyoti Shetty and Anjana J. Simpson and Ellen Sisk and Martti T. Tammi and Rick Tarleton and Santuza Teixeira and Susan Van Aken and Christy Vogt and Pauline N. Ward and Bill Wickstead and Jennifer Wortman and Owen White and Claire M. Fraser and Kenneth D. Stuart and Björn Andersson and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Uppsala universitet
Science, ISSN 0036-8075, 7/2005, Volume 309, Issue 5733, pp. 409 - 415
Whole-genome sequencing of the protozoan pathogen Trypanosoma cruzi revealed that the diploid genome contains a predicted 22,570 proteins encoded by genes, of... 
Proteins | Haplotypes | Retrotransposons | DNA | Mucins | Genomes | Parasitism | Research Articles | Parasites | Eukaryotic cells | Membrane proteins | AFRICAN TRYPANOSOMES | MULTILOCUS ENZYME ELECTROPHORESIS | NON-LTR RETROTRANSPOSONS | RNA INTERFERENCE RNAI | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | PARASITE PLASMODIUM-FALCIPARUM | AMPLIFIED POLYMORPHIC DNA | CLONE CL BRENER | NUCLEOTIDE-SEQUENCE | TRANS-SIALIDASE | Chagas Disease - parasitology | Multigene Family | Genome, Protozoan | Humans | Genes, Protozoan | Protozoan Proteins - genetics | DNA, Mitochondrial - genetics | Membrane Proteins - physiology | Recombination, Genetic | Protozoan Proteins - chemistry | Trypanocidal Agents - therapeutic use | Telomere - genetics | Signal Transduction | Membrane Proteins - genetics | Retroelements | Trypanosoma cruzi - genetics | DNA Replication | Meiosis | Protozoan Proteins - physiology | Sequence Analysis, DNA | Trypanosoma cruzi - physiology | Animals | Membrane Proteins - chemistry | Trypanocidal Agents - pharmacology | DNA Repair | Chagas Disease - drug therapy | Repetitive Sequences, Nucleic Acid | DNA, Protozoan - genetics | Trypanosoma cruzi - chemistry | Genetic aspects | Trypanosoma cruzi | Eukaryotes | Disease | Genomics | Genes | Parasitic protozoa | DNA repair | Chagas Disease/drug therapy/parasitology | Research Support; U.S. Gov't; P.H.S | Telomere/genetics | Recombination; Genetic | Repetitive Sequences; Nucleic Acid | Biology | Membrane Proteins/chemistry/genetics/physiology | Research Support; N.I.H.; Extramural | Trypanocidal Agents/pharmacology/therapeutic use | Genetics | Research Support; Non-U.S. Gov't | Biologi | Natural Sciences | Genes; Protozoan | Biological Sciences | DNA; Protozoan/genetics | Genome; Protozoan | Sequence Analysis; DNA | Genetik | Protozoan Proteins/chemistry/genetics/physiology | Naturvetenskap | Biologiska vetenskaper | Cell and molecular biology | Trypanosoma cruzi/chemistry/genetics/physiology | DNA; Mitochondrial/genetics | Cell- och molekylärbiologi
Journal Article
Journal Article