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Acta Ophthalmologica, ISSN 1755-375X, 11/2017, Volume 95, Issue 7, pp. 717 - 726
Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 2, pp. 273 - 282
RAP (receptor-associated protein) is a three domain 38 kDa ER (endoplasmic reticulum)-resident protein that is a chaperone for the LRP (low-density lipoprotein... 
Low-density lipoprotein receptor (LDLR) | Receptor-associated protein (RAP) | YWTD domain | Ligand release | LDLR-associated protein (LRP) | Chaperone | ER RETENTION | receptor-associated protein (RAP) | BIOCHEMISTRY & MOLECULAR BIOLOGY | low-density lipoprotein receptor (LDLR) | ULTRACENTRIFUGATION | ORGANIZATION | LDL-RECEPTOR | chaperone | ligand release | DISSECTION | LIGAND RECOGNITION | CALCIUM | MOLECULAR CHAPERONE | REPEATS | DOMAINS | Protein Structure, Tertiary | Temperature | Molecular Chaperones - metabolism | Low Density Lipoprotein Receptor-Related Protein-1 - chemistry | Low Density Lipoprotein Receptor-Related Protein-1 - metabolism | Models, Molecular | Spectrometry, Fluorescence | Molecular Chaperones - chemistry | LDL-Receptor Related Protein-Associated Protein - chemistry | Protein Folding | Protein Conformation | Kinetics | Binding Sites | LDL-Receptor Related Protein-Associated Protein - metabolism | Hydrogen-Ion Concentration | ITC, isothermal titration calorimetry | TEV, tobacco etch virus | RAP, receptor-associated protein | LA34, third and fourth CR domains from the ligand-binding cluster of LDLR | CR, complement-like repeat | CRxy, LRP fragment containing domains CRx and CRy | 2-ME, 2-mercaptoethanol | (CR)x LRP fragment containing x CR domains | D1, D2 and D3, first, second and third domains of RAP | IPTG, isopropyl β-D-thiogalactoside | CRxyz, LRP fragment containing domains CRx, CRy and CRz | LRP, low-density lipoprotein receptor-related protein | (V)LDLR, (very-) low-density lipoprotein receptor | GST, glutathione transferase | ER, endoplasmic reticulum
Journal Article
Journal Article
Journal Article
Mechanisms of Development, ISSN 0925-4773, 11/2013, Volume 130, Issue 11-12, pp. 628 - 639
Journal Article
Human Mutation, ISSN 1059-7794, 06/2010, Volume 31, Issue 6, pp. E1472 - E1483
Journal Article
Medicine, ISSN 0025-7974, 08/2018, Volume 97, Issue 32, p. e11499
Background:Cone-rod dystrophy (CORD) is an inherited, progressive retinal disorder with genetic and phenotypic heterogeneity. Here, we aimed to identify the... 
RETINOPATHIES | CRX mutation | VARIANTS | sanger sequencing | PHOTORECEPTOR | cosegregation analysis | MEDICINE, GENERAL & INTERNAL | LEBER CONGENITAL AMAUROSIS | cone-rod dystrophy | whole-exome sequencing | RETINITIS-PIGMENTOSA | HOMEOBOX GENE | TRANSCRIPTION FACTOR | Usage | Transcription factors | Nucleotide sequencing | Research | Gene mutations | DNA sequencing
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2005, Volume 280, Issue 12, pp. 11544 - 11551
In non-mammalian vertebrates, the pineal gland is photoreceptive and contains an intrinsic circadian oscillator that drives rhythmic production and secretion... 
EUKARYOTIC CIRCADIAN SYSTEMS | E-BOX | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | CRX | PINEAL-GLAND | MELATONIN SYNTHESIS | PROMOTER | EXPRESSION | SEROTONIN-N-ACETYLTRANSFERASE
Journal Article
Current Biology, ISSN 0960-9822, 03/2000, Volume 10, Issue 6, pp. 301 - 310
Background: Terminal differentiation of many cell types is controlled and maintained by tissue- or cell-specific transcription factors. Little is known,... 
Crx protein | CRX gene
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 07/2000, Volume 20, Issue 14, pp. 5216 - 5226
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2004, Volume 279, Issue 45, pp. 47233 - 47241
Journal Article
FEBS Letters, ISSN 0014-5793, 02/2010, Volume 584, Issue 4, pp. 753 - 758
Neuronal gene transcription is regulated by both transcriptional activators and repressors. While the roles of transactivators in retinal photoreceptor... 
Transcriptional cofactor | Retina | Repressor | Photoreceptor cell | Ankyrin repeat | Nr2e3 | orthodenticle homolog 2 | neural retina leucine zipper | Crx | Nrl | cone–rod homeobox | nuclear receptor subfamily 2 group E member 3 | Otx2 | LOCALIZATION | HOMEODOMAIN | NETWORK | ATAXIN-7 | BIOCHEMISTRY & MOLECULAR BIOLOGY | NRL | CELL FATE | DEGENERATION | CELL BIOLOGY | BIOPHYSICS | HOMEOBOX GENE | EXPRESSION | Repressor Proteins - classification | Homeodomain Proteins - metabolism | DNA, Complementary - genetics | Molecular Sequence Data | Gene Expression Profiling | Phylogeny | In Situ Hybridization | Base Sequence | Trans-Activators - genetics | Repressor Proteins - metabolism | Amino Acid Sequence | Cell Line | Gene Expression Regulation | Repressor Proteins - genetics | Photoreceptor Cells, Vertebrate - cytology | Ankyrin Repeat | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | DNA, Complementary - isolation & purification | Blotting, Western | Homeodomain Proteins - genetics | Transcription Factors - classification | Mice, Knockout | Sequence Homology, Amino Acid | Transcription Factors - metabolism | Blotting, Northern | Animals | Trans-Activators - metabolism | Mice | Mice, Inbred BALB C | Photoreceptor Cells, Vertebrate - metabolism | Genetic research | Photographic industry | Genetic aspects | DNA binding proteins | Analysis
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 02/2012, Volume 109, Issue 9, pp. E553 - E562
The generation of diverse neuronal types and subtypes from multipotent progenitors during development is crucial for assembling functional neural circuits in... 
Crx | Otx2 | Forkhead/winged-helix transcription factor | Proneural bHLH gene | HORIZONTAL CELLS | GANGLION-CELL | MULTIDISCIPLINARY SCIENCES | forkhead/winged-helix transcription factor | SPINAL-CORD | RECEPTOR | SPECIFICATION | GLYCINERGIC AMACRINE CELLS | MAMMALIAN RETINA | CONE PHOTORECEPTORS | proneural bHLH gene | DEVELOPING MOUSE RETINA | HOMEOBOX GENE | Retina - growth & development | Recombinant Fusion Proteins - physiology | Amacrine Cells - cytology | Forkhead Transcription Factors - physiology | Gene Expression Profiling | Retina - embryology | Cell Differentiation - genetics | Gene Expression Regulation, Developmental | Membrane Proteins - physiology | Conserved Sequence | Eye Proteins - genetics | Intracellular Signaling Peptides and Proteins - genetics | Forkhead Transcription Factors - deficiency | Genes, Reporter | Membrane Proteins - genetics | Receptors, Notch - physiology | Mice, Transgenic | Photoreceptor Cells, Vertebrate - cytology | Forkhead Transcription Factors - genetics | Mice, Knockout | Cell Lineage | Animals | Enhancer Elements, Genetic | Retinal Rod Photoreceptor Cells - cytology | Signal Transduction - physiology | Eye Proteins - physiology | Mice | Intracellular Signaling Peptides and Proteins - physiology | Biological Sciences | winged-helix transcription factor | PNAS Plus | forkhead
Journal Article