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The Journal of experimental medicine, ISSN 1540-9538, 2009, Volume 206, Issue 1, pp. 79 - 87
Influenza virus infection is recognized by the innate immune system through Toll like receptor (TLR) 7 and retinoic acid inducible gene I. These two... 
MEDICINE, RESEARCH & EXPERIMENTAL | STRANDED-RNA | DYING CELLS | HUMAN MACROPHAGES | INTERLEUKIN-1-BETA | INFECTION | IMMUNOLOGY | A-VIRUS | CASPASE-1 ACTIVATION | CRYOPYRIN/NALP3 | T-CELLS | NALP3 INFLAMMASOME | CD8-Positive T-Lymphocytes - cytology | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Receptors, Interleukin-1 - genetics | Immunity, Innate - genetics | Cell Movement - genetics | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Lung - virology | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Lung - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Macrophages, Alveolar - immunology | Macrophages, Alveolar - virology | Antibody Formation - immunology | Immunity, Cellular - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Mice, Knockout | Carrier Proteins - genetics | Immunity, Cellular - immunology | Immunity, Innate - immunology | Immunoglobulin Isotypes - blood | Animals | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Survival Analysis | Nasal Lavage Fluid - immunology | Immunoglobulin Isotypes - immunology | Mice | Macrophages, Alveolar - metabolism | CD8-Positive T-Lymphocytes - immunology | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Calcium-Binding Proteins - genetics | Multiprotein Complexes - immunology | Brief Definitive Reports
Journal Article
The Journal of infectious diseases, ISSN 1537-6613, 2012, Volume 205, Issue 5, pp. 807 - 817
Journal Article
Journal Article
Journal Article
European journal of immunology, ISSN 1521-4141, 2008, Volume 38, Issue 1, pp. 184 - 191
Synthesis and release of pro‐inflammatory cytokines, such as IL‐1β, play a crucial role in the intestinal inflammation that characterizes Crohn's disease.... 
Monocytes | Immune regulation | TLR | Cytokines | Gene expression | monocytes | INTERLEUKIN-1 | CROHNS-DISEASE | CASPASE-1 | SUSCEPTIBILITY | IMMUNOLOGY | CRYOPYRIN/NALP3 | immune regulation | RECEPTOR ANTAGONIST | MURAMYL DIPEPTIDE | INFLAMMASOME | MUTATION | cytokines | NF-KAPPA-B | gene expression
Journal Article
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, ISSN 1073-449X, 09/2010, Volume 182, Issue 6, pp. 774 - 783
Rationale: Pulmonary fibrosis is a devastating as yet untreatable disease. We previously investigated the endogenous mediators released on lung injury and... 
CASPASE-1 | pannexin-1 | P2X receptor | IDENTIFICATION | lung fibrosis | CRYOPYRIN/NALP3 | MOLECULES | TOLL-LIKE | EPITHELIAL-CELLS | inflammation | RESPIRATORY SYSTEM | HEMICHANNELS | INTERLEUKIN-1-BETA RELEASE | ATP | PULMONARY-FIBROSIS | CRITICAL CARE MEDICINE
Journal Article
Journal Article