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European journal of immunology, ISSN 0014-2980, 12/2016, Volume 46, Issue 12, pp. 2737 - 2748
The colony stimulating factor 1 receptor (CSF1R) functions as the major receptor for macrophage colony stimulating factor (CSF1) with crucial roles in... 
CSF1R | ADAM17 | metalloprotease | iRhom2 | myelopoiesis
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2019, Volume 162, pp. 161 - 175
Kinase irregularity has been correlated with several complex neurodegenerative tauopathies. Development of selective inhibitors of these kinases might afford... 
Tauopathies | CSF1R | Neuroinflammation | Multifunctional molecules | DAPK1 | Index Medicus
Journal Article
Journal of Clinical Neuroscience, ISSN 0967-5868, 02/2018, Volume 48, pp. 42 - 49
Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive degenerative white matter disorder. ALSP was previously... 
CSF1R | HDLS | POLD | Adult-onset | ALSP | Microgliopathy | Leukoencephalopathy | CSF1R MUTATION | DISEASE ENTITY | FRONTOTEMPORAL DEMENTIA | RECEPTOR | GENETIC-CHARACTERIZATION | NEUROSCIENCES | CLINICAL NEUROLOGY | IMPAIRMENT | FEATURES | FAMILY | PROGRESSIVE MULTIPLE-SCLEROSIS | NEUROAXONAL SPHEROIDS
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 57, pp. 96496 - 96505
Anti-angiogenesis therapy has shown clinical benefit in patients with high-grade serous ovarian cancer (HGSC), but adaptive resistance rapidly emerges. Thus,... 
Adaptive resistance | Tumor associated macrophages | Anti-VEGF therapy | Tumor microenvironment | CSF1R inhibition
Journal Article
OncoImmunology, ISSN 2162-4011, 09/2017, Volume 6, Issue 9, p. e1333213
M2-polarized (alternatively activated) macrophages play an important role in the progression of hepatocellular carcinoma (HCC). Allograft inflammatory factor 1... 
c-Jun | CSF1/CSF1R | AIF1 | hepatocellular carcinoma | CXCL16 | tumor-associated macrophages | CSF1R | ACTIVATION | PERITUMORAL LIVER-TISSUE | CSF1 | M-CSF | CURATIVE RESECTION | IMMUNOLOGY | CANCER | SIGNAL-TRANSDUCTION | ONCOLOGY | INFLAMMATORY FACTOR-I | GM-CSF | GENE-EXPRESSION | POLARIZATION
Journal Article
Cancer Cell, ISSN 1535-6108, 11/2017, Volume 32, Issue 5, pp. 654 - 668.e5
Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 01/2019, Volume 162, pp. 161 - 175
Kinase irregularity has been correlated with several complex neurodegenerative tauopathies. Development of selective inhibitors of these kinases might afford... 
CSF1R | Multifunctional molecules | CHEMISTRY, MEDICINAL | PROTEIN | DAPK1 | ALZHEIMERS-DISEASE | Neuroinflammation | TAU PATHOLOGY | MICROGLIAL PROLIFERATION | Tauopathies | POLYPHARMACOLOGY | CHANNELS | CELL | AGGREGATION | NITRATION
Journal Article
Internal Medicine, ISSN 0918-2918, 2017
We herein report the case of a 47-year-old female with the colony-stimulating factor 1 receptor (CSF1R) mutation p.G589R, which is related to hereditary... 
CSF1R | calcification | cognitive decline | hereditary diffuse leukoencephalopathy with spheroids
Journal Article
Journal Article
Voprosy Ginekologii, Akusherstva i Perinatologii, ISSN 1726-1678, 2018, Volume 17, Issue 2, pp. 43 - 47
Journal Article
Neurology, ISSN 0028-3878, 12/2018, Volume 91, Issue 24, pp. 1092 - 1104
Since the discovery of CSF1R gene mutations in families with hereditary diffuse leukoencephalopathy with spheroids in 2012, more than 70 different mutations... 
CSF1R MUTATION | MOVEMENT-DISORDERS | HDLS | HEREDITARY DIFFUSE LEUKOENCEPHALOPATHY | AXONAL SPHEROIDS | NEUROAXONAL SPHEROIDS | LEUKODYSTROPHY | ADULT-ONSET LEUKOENCEPHALOPATHY | PIGMENTED GLIA | DWI CHANGES | CLINICAL NEUROLOGY
Journal Article