Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (12) 12
gene csnk2a1 (10) 10
casein kinase ii (7) 7
csnk2a1 (7) 7
index medicus (7) 7
phosphorylation (7) 7
casein kinase ii - genetics (6) 6
cell biology (6) 6
animals (5) 5
genetics & heredity (5) 5
kinases (5) 5
protein kinase ck2 (5) 5
saccharomyces-cerevisiae (5) 5
beta-subunit (4) 4
biochemistry & molecular biology (4) 4
biochemistry, general (4) 4
casein kinase ii - metabolism (4) 4
csnk2a1 gene (4) 4
genes (4) 4
genetic aspects (4) 4
intellectual disability (4) 4
life sciences (4) 4
male (4) 4
molecular sequence data (4) 4
oncology (4) 4
adult (3) 3
alpha-subunit (3) 3
analysis (3) 3
cardiology (3) 3
casein kinase (3) 3
casein kinase-2 (3) 3
cellular-regulation (3) 3
cloning, molecular (3) 3
female (3) 3
ii-alpha (3) 3
medical biochemistry (3) 3
mice (3) 3
middle aged (3) 3
mutation (3) 3
neurodevelopmental disorders (3) 3
prognosis (3) 3
protein-kinase ck2 (3) 3
protein-serine-threonine kinases - metabolism (3) 3
proteins (3) 3
aac-11 (2) 2
adnp (2) 2
aged (2) 2
ahdc1 (2) 2
amino acid sequence (2) 2
ankrd11 (2) 2
apoptosis (2) 2
arid1b (2) 2
article (2) 2
asxl3 (2) 2
base sequence (2) 2
bcl11a (2) 2
biotechnology & applied microbiology (2) 2
braf (2) 2
caenorhabditis-elegans (2) 2
carcinoma (2) 2
casein kinase ii - biosynthesis (2) 2
casein kinase-ii (2) 2
cask (2) 2
catalytic domain (2) 2
cdk13 (2) 2
cells (2) 2
champ1 (2) 2
chd2 (2) 2
chd8 (2) 2
chromosome 16 (2) 2
ck2 (2) 2
cloning (2) 2
cnksr2 (2) 2
cohort studies (2) 2
col4a3bp (2) 2
crebbp (2) 2
ctcf (2) 2
ctnnb1 (2) 2
ddx3x (2) 2
de novo mutation (2) 2
de-novo mutations (2) 2
developmental delay (2) 2
developmental disabilities - genetics (2) 2
developmental regulation (2) 2
disorders (2) 2
disruption (2) 2
dna (2) 2
dna, complementary (2) 2
dna-binding (2) 2
dync1h1 (2) 2
dyrk1a (2) 2
dysmorphic features (2) 2
eef1a2 (2) 2
ehmt1 (2) 2
enzymes (2) 2
ep300 (2) 2
exome - genetics (2) 2
expression (2) 2
flow cytometry (2) 2
foxg1 (2) 2
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Okur‐Chung neurodevelopmental syndrome: Eight additional cases with implications on phenotype and genotype expansion
by Chiu, A.T.G and Pei, S.L.C and Mak, C.C.Y and Leung, G.K.C and Yu, M.H.C and Lee, S.L and Vreeburg, M and Pfundt, R and van der Burgt, I and Kleefstra, T and Frederic, T.M.‐T and Nambot, S and Faivre, L and Bruel, A.‐L and Rossi, M and Isidor, B and Küry, S and Cogne, B and Besnard, T and Willems, M and Reijnders, M.R.F and Chung, B.H.Y
Clinical Genetics, ISSN 0009-9163, 04/2018, Volume 93, Issue 4, pp. 880 - 890
Okur‐Chung syndrome is a neurodevelopmental condition attributed to germline CSNK2A1 pathogenic missense variants. We present 8 unreported subjects with the... 
Okur‐Chung syndrome | developmental delay | CSNK2A1 | whole exome sequencing | Okur-Chung syndrome | NETWORK | ABNORMALITIES | PROTEIN-KINASE CK2 | CATALYTIC-SUBUNIT | DISORDERS | PROLIFERATION | INTELLECTUAL DISABILITY | DE-NOVO MUTATIONS | GENETICS & HEREDITY | DYSMORPHIC FEATURES | Enzymes | Genetic aspects | Phenotypes | Microencephaly | Protein kinase | Evolutionary conservation | Ear | Csnk2a1 gene | Neurodevelopmental disorders | Kinases | Genotypes | Life Sciences | Human health and pathology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Prevalence and architecture of de novo mutations in developmental disorders
by McRae, Jeremy F and Clayton, Stephen and Fitzgerald, Tomas W and Kaplanis, Joanna and Prigmore, Elena and Rajan, Diana and Sifrim, Alejandro and Aitken, Stuart and Akawi, Nadia and Alvi, Mohsan and Ambridge, Kirsty and Barrett, Daniel M and Bayzetinova, Tanya and Jones, Philip and Jones, Wendy D and King, Daniel and Krishnappa, Netravathi and Mason, Laura E and Singh, Tarjinder and Tivey, Adrian R and Ahmed, Munaza and Anjum, Uruj and Archer, Hayley and Armstrong, Ruth and Awada, Jana and Balasubramanian, Meena and Banka, Siddharth and Baralle, Diana and Barnicoat, Angela and Batstone, Paul and Baty, David and Bennett, Chris and Berg, Jonathan and Bernhard, Birgitta and Bevan, A. Paul and Bitner-Glindzicz, Maria and Blair, Edward and Blyth, Moira and Bohanna, David and Bourdon, Louise and Bourn, David and Bradley, Lisa and Brady, Angela and Brent, Simon and Brewer, Carole and Brunstrom, Kate and Bunyan, David J and Burn, John and Canham, Natalie and Castle, Bruce and Chandler, Kate and Chatzimichali, Elena and Cilliers, Deirdre and Clarke, Angus and Clasper, Susan and Clayton-Smith, Jill and Clowes, Virginia and Coates, Andrea and Cole, Trevor and Colgiu, Irina and Collins, Amanda and Collinson, Morag N and Connell, Fiona and Cooper, Nicola and Cox, Helen and Cresswell, Lara and Cross, Gareth and Crow, Yanick and D'Alessandro, Mariella and Dabir, Tabib and Davidson, Rosemarie and Davies, Sally and De Vries, Dylan and Dean, John and Deshpande, Charu and Devlin, Gemma and Dixit, Abhijit and Dobbie, Angus and Donaldson, Alan and Donnai, Dian and Donnelly, Deirdre and Donnelly, Carina and Douglas, Angela and Douzgou, Sofia and Duncan, Alexis and Eason, Jacqueline and Ellard, Sian and Ellis, Ian and Elmslie, Frances and Evans, Karenza and Everest, Sarah and Fendick, Tina and Fisher, Richard and Flinter, Frances and Foulds, Nicola and Fry, Andrew and Fryer, Alan and Gardiner, Carol and Gaunt, Lorraine and Ghali, Neeti and ... and Deciphering Developmental Disorders Study
Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 433 - 438
The genomes of individuals with severe, undiagnosed developmental disorders are enriched in damaging de novo mutations (DNMs) in developmentally important... 
INTELLECTUAL DISABILITY | METAANALYSIS | VARIANTS | GENETICS | HEART-DEFECTS | MULTIDISCIPLINARY SCIENCES | GENES | SEQUENCE | FRAMEWORK | DISCOVERY | GENOME | Prevalence | Humans | Middle Aged | Parents | Male | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | Developmental Disabilities - genetics | Casein Kinase II - genetics | Autoantigens - genetics | Young Adult | ras GTPase-Activating Proteins - genetics | Adult | Female | Child | CDC2 Protein Kinase - genetics | Histone-Lysine N-Methyltransferase - genetics | Repressor Proteins - genetics | Sex Characteristics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mutation - genetics | Nerve Tissue Proteins - genetics | Sequence Analysis, DNA | Homeodomain Proteins - genetics | DEAD-box RNA Helicases - genetics | Exome - genetics | Phenotype | Myeloid-Lymphoid Leukemia Protein - genetics | Adolescent | Heredity - genetics | Protein Phosphatase 2C - genetics | Cohort Studies | Child development deviations | Genetic aspects | Genetic disorders | Developmental disabilities | Distribution | Genes | Families & family life | Births | Genomes | Mutation | Causality | Estimates | Age | TRIO | MYT1L | EHMT1 | HNRNPU | SUV420H1 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SCN1A | MEF2C | CDKL5 | CSNK2A1 | DYRK1A | CASK | ALG13 | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | PhenIcons | SET | KMT2A | ANKRD11 | STXBP1 | FOXG1 | ZC4H2 | ITPR1 | De novo mutation | Seizures | ZBTB18 | CREBBP | SMAD4 | PDHA1 | IQSEC2 | AUTS2 | BCL11A | BRAF | SMARCA2 | GRIN2B | MED13L | GNAO1 | CNOT3 | TCF4 | SCN2A | CDK13 | GABRB3 | SETD5 | KDM5B | Developmental Disease | DDX3X | CHD8 | PTEN | CHD4 | TCF20 | CTCF | CHD2 | WDR45 | SLC6A1 | MECP2 | CHAMP1 | KIF1A | Average Faces | MSL3 | PPP2R5D | SMC1A | ARID1B | DNM1 | CNKSR2 | PACS1 | WAC | ZMYND11 | AHDC1 | NFIX | SATB2 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | Intellectual Disability | SLC35A2 | DYNC1H1 | NAA10 | USP9X | PTPN11 | GATAD2B | ASXL1 | KANSL1 | ASXL3 | CTNNB1 | QRICH1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Extending the phenotype associated with the CSNK2A1‐related Okur–Chung syndrome—A clinical study of 11 individuals
by Owen, Ceris I and Bowden, Ramsay and Parker, Michael J and Patterson, Jo and Patterson, Joan and Price, Sue and Sarkar, Ajoy and Castle, Bruce and Deshpande, Charulatha and Splitt, Miranda and Ghali, Neeti and Dean, John and Green, Andrew J and Crosby, Charlene and Tatton‐Brown, Katrina and Deciphering Dev Disorders Study and Deciphering Developmental Disorders Study
American Journal of Medical Genetics Part A, ISSN 1552-4825, 05/2018, Volume 176, Issue 5, pp. 1108 - 1114
Variants in the Protein Kinase CK2 alpha subunit, encoding the CSNK2A1 gene, have previously been reported in children with an intellectual disability and... 
protein kinase CK2 | Okur–Chung | CSNK2A1 | DDD study | intellectual disability | SEVERE INTELLECTUAL DISABILITY | GENOMIC ORGANIZATION | PROMOTER IDENTIFICATION | PROTEIN-KINASE CK2 | Okur-Chung | DE-NOVO MUTATIONS | NEURODEVELOPMENTAL ABNORMALITIES | GENETICS & HEREDITY | SUBUNIT-ALPHA | DYSMORPHIC FEATURES | DEVELOPMENTAL DISORDERS | Clinical trials | Medicine, Experimental | Medical research | Genetic aspects | Genetic disorders | Protein kinase C | Phenotypes | Intellectual disabilities | Phenotyping | Csnk2a1 gene | Children | Neurodevelopmental disorders | Swallowing | Kinases | Casein kinase II
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Neurodevelopmental disease genes implicated by de novo mutation and copy number variation morbidity
by Coe, Bradley P and Stessman, Holly A. F and Sulovari, Arvis and Geisheker, Madeleine R and Bakken, Trygve E and Lake, Allison M and Dougherty, Joseph D and Lein, Ed S and Hormozdiari, Fereydoun and Bernier, Raphael A and Eichler, Evan E
Nature Genetics, ISSN 1061-4036, 01/2019, Volume 51, Issue 1, pp. 106 - 116
We combined de novo mutation (DNM) data from 10,927 individuals with developmental delay and autism to identify 253 candidate neurodevelopmental disease genes... 
INTELLECTUAL DISABILITY | AUTISM | MOUSE MODEL | GENETICS & HEREDITY | MISSENSE MUTATION | SEGMENTAL DUPLICATIONS | DEVELOPMENTAL DELAY | SPECTRUM | TRUNCATING MUTATIONS | CLINICAL-SIGNIFICANCE | HAPLOINSUFFICIENCY | Autistic Disorder - genetics | Humans | Mi-2 Nucleosome Remodeling and Deacetylase Complex - genetics | DNA Copy Number Variations - genetics | Developmental Disabilities - genetics | Neurodevelopmental Disorders - genetics | Mutation - genetics | Intellectual Disability - genetics | Exome - genetics | Phenotype | Animals | Chromosome Aberrations | Polymorphism, Single Nucleotide - genetics | Mice | Intracellular Signaling Peptides and Proteins - genetics | Gene mutations | Copy number variations | Analysis | Nervous system | Degeneration | Genetic aspects | Research | Morbidity | Neurosciences | Intellectual disabilities | Copy number | Genes | Disorders | Likelihood ratio | Genomes | Gene deletion | Neurodevelopmental disorders | Spiny neurons | Autism | Missense mutation | Clonal deletion | Reproduction (copying) | Neostriatum | Deletion | Gene duplication | Mutation | Chromosome 16 | TRIO | MYT1L | HNRNPU | EHMT1 | ENO3 | CAPN15 | SUV420H1 | PPP1CB | EFTUD2 | COL4A3BP | SYNGAP1 | PPP2R1A | POGZ | EP300 | KCNH1 | SOX5 | MAP2K1 | MEF2C | CSNK2A1 | TMEM178A | DYRK1A | CASK | FOXP1 | KAT6B | TBL1XR1 | KAT6A | SCN8A | HECW2 | KCNQ2 | EEF1A2 | KCNQ3 | ADNP | Genetics of Developmental Delay | DLX3 | SET | KMT2A | SRCAP | ANP32A | STXBP1 | CUL3 | FOXG1 | ANKRD11 | ITPR1 | de novo Mutation | HIVEP3 | SNX5 | ZBTB18 | CREBBP | IQSEC2 | BCL11A | NONO | UPF3B | BRAF | ADAP1 | GRIN2B | SMARCA2 | SMARCA4 | MED13L | GNAO1 | AGO4 | DLG4 | CAPRIN1 | Neurodevelopmental Disorders | TCF4 | CDK13 | SCN2A | GABRB2 | KDM5B | SETD5 | DDX3X | CHD8 | PTEN | TCF20 | CTCF | CHD3 | CHD2 | WDR45 | SLC6A1 | MECP2 | SNAPC5 | SYNCRIP | TLK2 | CHAMP1 | KIF1A | RAC1 | TNPO2 | DNMT3A | MSL3 | PPP2R5D | ASH1L | SMC1A | ARID1B | CNKSR2 | PACS2 | SETBP1 | PIK3CA | PACS1 | WAC | ZMYND11 | SHANK3 | AHDC1 | SMARCD1 | WDR26 | NFIX | SATB2 | KIAA2022 | HDAC8 | PPM1D | GNAI1 | PURA | PUF60 | NSD1 | LEO1 | DYNC1H1 | MBD5 | NAA10 | USP9X | PTPN11 | MEIS2 | GATAD2B | KANSL1 | ASXL3 | CTNNB1 | TRIP12 | QRICH1 | NAA15 | TAF1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text PKCζ Phosphorylates SIRT6 to Mediate Fatty Acid β-Oxidation in Colon Cancer Cells
by Gao, Tian and Li, Meiting and Mu, Guanqun and Hou, Tianyun and Zhu, Wei-Guo and Yang, Yang
Neoplasia, ISSN 1476-5586, 01/2019, Volume 21, Issue 1, pp. 61 - 73
Protein kinase C (PKC) has critical roles in regulating lipid anabolism and catabolism. PKCζ, a member of atypical PKC family, has been reported to mediate... 
Chromatin - metabolism | Colonic Neoplasms - genetics | Phosphorylation | Oxidation-Reduction | Humans | Gene Expression Regulation, Neoplastic | Colonic Neoplasms - metabolism | Protein Kinase C - metabolism | Cell Line, Tumor | Protein Binding | Chromatin - genetics | Fatty Acids - metabolism | Sirtuins - metabolism | Protein kinase C | Chromatin | Threonine | Tumor cells | Colorectal cancer | Homeostasis | Palmitic acid | Kinases | Fatty acids | Phosphorylase | Glucose metabolism | Colon cancer | Oxidation | Lipid metabolism | Colon
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Molecular characterization of clear cell renal cell carcinoma identifies CSNK2A1, SPP1 and DEFB1 as promising novel prognostic markers
by Rabjerg, Maj and Bjerregaard, Henriette and Halekoh, Ulrich and Jensen, Boye L and Walter, Steen and Marcussen, Niels
APMIS, ISSN 0903-4641, 05/2016, Volume 124, Issue 5, pp. 372 - 383
The prognosis associated with clear cell renal carcinoma (cc RCC ) can vary widely and novel molecular prognostic markers are needed to assess prognosis at an... 
CSNK | 2A1 | SPP | DEFB | RCC | Taqman Array | prognosis | SPP1 | DEFB1 | Prognosis | CSNK2A1 | CcRCC | Osteopontin - genetics | Follow-Up Studies | Humans | Middle Aged | Molecular Sequence Data | RNA, Messenger - analysis | Male | Gene Expression Profiling | Casein Kinase II - genetics | Kidney Neoplasms - diagnosis | Osteopontin - biosynthesis | Aged, 80 and over | Adult | Female | beta-Defensins - genetics | Casein Kinase II - biosynthesis | Biomarkers, Tumor - analysis | Carcinoma, Renal Cell - pathology | RNA, Messenger - genetics | Sequence Analysis, DNA | Carcinoma, Renal Cell - diagnosis | Survival Analysis | Kidney Neoplasms - pathology | Aged | beta-Defensins - biosynthesis | Cohort Studies | Carcinoma | RNA | Analysis | Development and progression | Chemical properties | Cancer | Multivariate analysis | Genes | Medical prognosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text The cytosolic protein kinase CK2 phosphorylates cardiac calsequestrin in intact cells
by McFarland, Timothy P and Sleiman, Naama H and Yaeger, Daniel B and Cala, Steven E
Molecular and Cellular Biochemistry, ISSN 0300-8177, 7/2011, Volume 353, Issue 1, pp. 81 - 91
The luminal SR protein CSQ2 contains phosphate on roughly half of the serines found in its C-terminus. The sequence around phosphorylation sites in CSQ2... 
Biochemistry, general | Calsequestrin | Phosphorylation | Rough ER | Medical Biochemistry | Oncology | siRNA | Glycosylation | CK2 | Life Sciences | Sarcoplasmic reticulum | Cardiology | Kinase inhibitors | SKELETAL-MUSCLE CALSEQUESTRIN | IDENTIFICATION | CELL BIOLOGY | HEART | AMINO-ACID-SEQUENCE | PURIFICATION | GENE CSNK2A1 | SITES | INHIBITORS | SARCOPLASMIC-RETICULUM VESICLES | SUBUNIT | Cercopithecus aethiops | Endoplasmic Reticulum - metabolism | Calsequestrin - genetics | Casein Kinase II - genetics | Protein Subunits - metabolism | Cytosol - enzymology | RNA Interference | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Phosphorylation - drug effects | Calsequestrin - metabolism | Protein-Serine-Threonine Kinases - metabolism | Protein Subunits - genetics | Myocytes, Cardiac - cytology | Electrophoresis, Polyacrylamide Gel | Casein Kinase II - antagonists & inhibitors | Cells, Cultured | Rats | Cinnamates - pharmacology | Triazoles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - metabolism | Benzimidazoles - pharmacology | Protein Subunits - antagonists & inhibitors | Mutation | COS Cells | Casein Kinase II - metabolism | Amino Acid Substitution | Phosphates | Enzymes | Calcium-binding proteins | Protein kinases | Analysis | Proteins | Ribonucleic acid--RNA | Cells
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Differential localization of α' and β subunits of protein kinase CK2 during rat spermatogenesis
by Alvarado-Díaz, Carlos P and Tapia, Julio C and Antonelli, Marcelo and Moreno, Ricardo D
Cell and Tissue Research, ISSN 0302-766X, 10/2009, Volume 338, Issue 1, pp. 139 - 149
Protein kinase CK2 is a serine/threonine kinase expressed in organisms from yeast to human and is composed of a catalytic subunit (alpha or alpha') and a... 
Cytoskeleton | Meiosis | Rat (Sprague Dawley) | CK2 | Spermatogenesis | Cell cycle | HUMAN SPERMATOZOA | FERTILIZATION | PHOSPHORYLATION | BLOOD-TESTIS BARRIER | SPERMIOGENESIS | MICE LACKING | CELL BIOLOGY | GLOBOZOOSPERMIA | REGULATOR | SPERM | GENE CSNK2A1 | Testis - cytology | Humans | Rats | Male | Casein Kinase II - genetics | Rats, Sprague-Dawley | Protein Subunits - metabolism | Testis - physiology | Casein Kinase II - chemistry | Spermatogenesis - physiology | Animals | Protein Subunits - chemistry | Spermatozoa - cytology | Casein Kinase II - metabolism | Protein Subunits - genetics | Spermatozoa - enzymology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Gene expression levels of CSNK1A1 and AAC-11, but not NME1, in tumor tissues as prognostic factors in NSCLC patients
by Wang, Zhuomin and Liu, Hongyu and Liu, Baoxing and Ma, Wei and Xue, Xingyang and Chen, Jun and Zhou, Qinghua
Medical Science Monitor, ISSN 1234-1010, 2010, Volume 16, Issue 8, pp. CR357 - CR364
Background: To analyze the prognostic significance of the genes casein kinase 2 a subunit (CSNK2A1), antiapoptosis clone-11 (AAC-11), and tumor metastasis... 
Prognosis | AAC-11 | CSNK2A1 | NSCLC | RT-PCR | NME1 | SURVIVAL | MEDICINE, RESEARCH & EXPERIMENTAL | CASEIN KINASE-2 | APOPTOSIS | PROTEIN-KINASE CK2 | STAGE-I | prognosis | PREDICTION | CELL LUNG-CANCER | BREAST-CANCER | CARCINOMA | NM23 EXPRESSION | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Male | Carcinoma, Non-Small-Cell Lung - diagnosis | Casein Kinase II - genetics | RNA, Messenger - metabolism | NM23 Nucleoside Diphosphate Kinases - genetics | NM23 Nucleoside Diphosphate Kinases - metabolism | Apoptosis Regulatory Proteins - genetics | Adult | Female | Nuclear Proteins - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Messenger - genetics | Kaplan-Meier Estimate | Nuclear Proteins - metabolism | Apoptosis Regulatory Proteins - metabolism | Aged | Carcinoma, Non-Small-Cell Lung - enzymology | Lung Neoplasms - diagnosis | Casein Kinase II - metabolism
Journal Article
Details down arrow
10. Full Text Inducible expression of protein kinase CK2 in mammalian cells. Evidence for functional specialization of CK2 isoforms
by Vilk, Greg and Saulnier, Ronald B and St. Pierre, Rebecca and Litchfield, David W
Journal of Biological Chemistry, ISSN 0021-9258, 05/1999, Volume 274, Issue 20, pp. 14406 - 14414
Protein kinase CK2 (formerly casein kinase II) exhibits elevated expression in a variety of cancers, induces lymphocyte transformation in transgenic mice, and... 
CASEIN KINASE-2 | DNA-BINDING | CELLULAR-REGULATION | ALPHA-SUBUNIT | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE CSNK2A1 | CYCLE PROGRESSION | SACCHAROMYCES-CEREVISIAE | BETA-SUBUNIT | II-ALPHA | Casein Kinase II | Humans | Tetracycline - pharmacology | Enzyme Induction | Structure-Activity Relationship | DNA-Binding Proteins - metabolism | Protein-Serine-Threonine Kinases - biosynthesis | Animals | Isoenzymes - metabolism | Plasmids | Cell Division | Mice | Isoenzymes - biosynthesis | Protein-Serine-Threonine Kinases - metabolism
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Validation of protein kinase CK2 as oncological target
by Seeber, S and Issinger, O G and Holm, T and Kristensen, L P and Guerra, B
Apoptosis, ISSN 1360-8185, 8/2005, Volume 10, Issue 4, pp. 875 - 885
Protein kinase CK2 is a highly conserved enzyme composed of two catalytic subunits α and/or α′ and two regulatory subunits β whose activity is elevated in... 
Biochemistry, general | protein kinase CK2 | Medicine & Public Health | Cancer Research | Oncology | apoptosis | siRNA duplex | Virology | Cell Biology | antisense oligodeoxynucleotide | Antisense oligodeoxynucleotide | Protein kinase CK2 | Apoptosis | CANCER-CELLS | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CASEIN KINASE | NEUROBLASTOMA-CELLS | II-ALPHA | P53 | CELL BIOLOGY | INHIBITION | GENE CSNK2A1 | CATALYTIC-ACTIVITY | SUBUNIT | Catalytic Domain | Reproducibility of Results | Casein Kinase II - biosynthesis | Oligonucleotides, Antisense - pharmacology | Apoptosis - drug effects | Jurkat Cells | HCT116 Cells | Humans | RNA, Small Interfering - pharmacology | Nocodazole - pharmacology | Neoplasms - enzymology | Casein Kinase II - genetics | Flow Cytometry | Cell Transformation, Neoplastic | RNA, Messenger - antagonists & inhibitors | Casein Kinase II - deficiency | HeLa Cells | Casein Kinase II - metabolism | Proteins | Protein kinases | Kinases
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights