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Journal Article
Kidney international, ISSN 0085-2538, 3/2017, Volume 91, Issue 3, pp. 628 - 641
The expansion of the fibroblast pool is a critical step in organ fibrosis, but the mechanisms driving expansion remain to be fully clarified. We previously... 
fibroblast | Fibrosis | LPA1 | CTGF
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 50, pp. 87086 - 87094
Kahweol is a diterpene molecule found in Coffea Arabica beans. Previous studies have shown that coffee reduces liver fibrosis, but it is not clear which... 
Hepatic fibrosis | TGF-β | Kahweol | CTGF | PHOSPHORYLATION | LIVER FIBROSIS | COFFEE CONSUMPTION | CELL-PROLIFERATION | CTGF/CCN2 | DAMAGE | kahweol | CELL BIOLOGY | CTGF EXPRESSION | CAFESTOL | TGF-beta | DISEASE | hepatic fibrosis
Journal Article
Matrix biology : journal of the International Society for Matrix Biology, ISSN 0945-053X, 02/2019
Muscular fibrosis is caused by excessive accumulation of extracellular matrix (ECM) that replaces functional tissue, and it is a feature of several myopathies... 
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 10/2016, Volume 57, Issue 13, pp. 5171 - 5180
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 05/2009, Volume 107, Issue 2, pp. 345 - 356
Tumor malignancy is associated with several features such as proliferation ability and frequency of metastasis. Connective tissue growth factor (CTGF), a... 
chondrosarcoma | migration | MMP‐13 | integrin | CTGF | MMP-13 | Chondrosarcoma | Integrin | Migration
Journal Article
PLOS ONE, ISSN 1932-6203, 11/2014, Volume 9, Issue 11
Introduction: Encapsulating peritoneal sclerosis (EPS) is a devastating complication of peritoneal dialysis (PD). The pathogenesis is not exactly known and no... 
FIBROSIS | FACTOR CTGF/CCN2 | CYTOKINES | TGF-BETA | MEMBRANE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MORPHOLOGIC CHANGES | INHIBITOR | CTGF | TGF-BETA-1
Journal Article
Journal Article
Journal Article
Journal Article
BBA - Gene Regulatory Mechanisms, ISSN 1874-9399, 06/2019, Volume 1862, Issue 6, pp. 609 - 618
Although hepatic stellate cells (HSC) represent the major source of fibrogenesis in the liver under various pathological conditions, other cell types including... 
Liver fibrosis | Hepatic stellate cell | Hepatocyte | Transcriptional regulation | CTGF
Journal Article
Connective Tissue Research, ISSN 0300-8207, 01/2018, Volume 59, Issue 1, pp. 30 - 44
Journal Article
Chest, ISSN 0012-3692, 04/2018, Volume 153, Issue 4, pp. 851 - 862
Journal Article
by Li, SB and Pan, YH
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER, ISSN 0940-9602, 2018, Volume 216, pp. 52 - 59
Connective tissue growth factor (CTGF) is a downstream mediator of transforming growth factor-beta 1 (TGF-beta(1)) and TGF-beta(1)-induced CTGF expression is... 
SMAD2 | CELLS | APOPTOSIS | Junctional epithelium | Tooth development | IMMUNOHISTOCHEMICAL LOCALIZATION | ANATOMY & MORPHOLOGY | Connective tissue growth factor | Transforming growth factor-beta | Phosphorylated-SMAD2/3 | CTGF/CCN2 | FACTOR CTGF | PROTEINS | EXPRESSION | CCN2/CTGF | REPARATIVE DENTINOGENESIS
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 4/2015, Volume 194, Issue 7, pp. 3422 - 3431
Journal Article
CELL AND TISSUE RESEARCH, ISSN 0302-766X, 12/2018, Volume 374, Issue 3, pp. 619 - 627
Renal tubular epithelial cells actively contribute to the development of renal fibrosis and may be targeted by anti-fibrotic drugs. Relaxin-2 (RLX2) applied as... 
Transforming growth factor beta | IDENTIFICATION | RXFP1 | Fibronectin | CTGF | Relaxin-2 | BETA | CELL BIOLOGY | MMP | Human primary renal epithelial cells | TISSUE GROWTH-FACTOR | FAMILY PEPTIDES | EXPERIMENTAL-MODEL | ROLES | FACTOR CTGF | HORMONE RELAXIN | UP-REGULATION | EXPRESSION
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2018, Volume 495, Issue 1, pp. 1447 - 1453
CCN2, also known as connective tissue growth factor (CTGF), is a 38 kDa cysteine-rich extracellular matrix protein that regulates a sequence of cellular... 
PI3k/Akt | CCN2 | Proliferation | Condylar chondrocyte | Differentiation | CTGF | RAT | CTGF/HCS24 | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOPHYSICS | GENE | PRODUCT | OSTEOARTHRITIS | CHONDROGENESIS | FEMORAL-HEAD | Physiological aspects | Cysteine | Analysis | Cystine | Index Medicus
Journal Article
Journal of Dermatological Science, ISSN 0923-1811, 04/2019, Volume 94, Issue 1, pp. 205 - 212
Systemic sclerosis (SSc) is characterized by fibrosis of the skin and internal organs. Although transforming growth factor (TGF)-β1-induced connective tissue... 
TGF-β1 | Akt | Angiotensin II | COA-Cl | CTGF
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2008, Volume 49, Issue 5, pp. 758 - 767
Background/Aims Epidemiological studies suggest that coffee drinking is inversely correlated with the risk of development of liver fibrosis but the molecular... 
Gastroenterology and Hepatology | TGF-β | Smad2/3 | cAMP | PPARγ | CTGF | Caffeine | UNITED-STATES | FACTOR CTGF/CCN2 | LIVER FIBROSIS | RECEPTOR | BINDING PROTEIN | PPAR gamma | TGF-beta | HEPATIC STELLATE CELLS | GENE-EXPRESSION | SMOOTH-MUSCLE-CELLS | GASTROENTEROLOGY & HEPATOLOGY | CONSUMPTION
Journal Article