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Cancer Discovery, ISSN 2159-8274, 09/2018, Volume 8, Issue 9, pp. 1069 - 1086
Immune checkpoint blockade is able to induce durable responses across multiple types of cancer, which has enabled the oncology community to begin to envision... 
CTLA-4 COUNTER-RECEPTOR | TERTIARY LYMPHOID STRUCTURES | FC-GAMMA RECEPTORS | DENDRITIC CELLS | ONCOLOGY | LONG-TERM SURVIVAL | REGULATORY T-CELLS | FACTOR RECEPTOR SUPERFAMILY | COSTIMULATORY MOLECULE | CANCER-IMMUNOTHERAPY | CUTTING EDGE
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 12/1993, Volume 178, Issue 6, pp. 2185 - 2192
The B7-1 molecule, expressed on antigen presenting cells (APC), provides a crucial costimulatory signal for T cell activation. Recent studies demonstrate the... 
B-CELLS | SIGNAL | MEDICINE, RESEARCH & EXPERIMENTAL | SUPERFAMILY | MOLECULAR-CLONING | ANERGY | INDUCTION | PROVIDES | IMMUNOLOGY | EXPRESSION | CLONES | ACTIVATION ANTIGEN-B7
Journal Article
International Immunology, ISSN 0953-8178, 02/2013, Volume 25, Issue 2, pp. 129 - 137
Journal Article
Annals of Surgery, ISSN 0003-4932, 12/2010, Volume 252, Issue 6, pp. 1044 - 1051
Objective: B7 ligand family members have been shown to be important immunoregulatory factors in host tumor immune responses. We hypothesized that B7-H3, a... 
SURGERY | NODES | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | POTENTIAL TARGET | B7 FAMILY | ANTIBODY BLOCKADE | CTLA-4 | MELANOMA PATIENTS | RENAL-CELL CARCINOMA | COUNTER-RECEPTOR | TUMOR-CELL | Receptors, Immunologic - biosynthesis | Antigens, CD - biosynthesis | Breast Neoplasms - pathology | Humans | Axilla | Female | Ligands | Lymphatic Metastasis | B7 Antigens | Breast Neoplasms - metabolism
Journal Article
Annual Review of Immunology, ISSN 0732-0582, 04/1996, Volume 14, Issue 1, pp. 233 - 258
T cells play a central role in the initiation and regulation of the immune response to antigen. Both the engagement of the TCR with MHC/Ag and a second signal... 
CTLA4Ig | autoimmunity | T cell activation | tolerance | ACTIVATION | INDUCTION | IMMUNOLOGY | MURINE HOMOLOG | B-CELLS | CTLA-4 COUNTER-RECEPTOR | MESSENGER-RNA | EXPRESSION | LYMPHOCYTES-T | ADDITIONAL LIGAND | ANTIGEN | CD28 Antigens - physiology | B7-1 Antigen - physiology | T-Lymphocytes - immunology | Animals | Lymphocyte Activation | Humans
Journal Article