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Biochemical journal, ISSN 1470-8728, 10/2005, Volume 391, Issue 2, pp. 153 - 166
.... While these outcomes are initially determined by the nature of the ligand and its receptor, it is also essential that intracellular enzymes, adaptor proteins and transcription factors are correctly... 
T-cell receptor | Ubiquitin | Receptor tyrosine kinase | E3 ligase | Cbl | Thymocyte | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | Proto-Oncogene Proteins c-cbl - genetics | Proto-Oncogene Proteins c-cbl - metabolism | Animals | Signal Transduction | Substrate Specificity | Proto-Oncogene Proteins c-cbl - chemistry | Proto-Oncogene Proteins c-cbl - immunology | Index Medicus | PLC, phospholipase C | SH, Src homology | TCR, T-cell receptor | IL-2, interleukin 2 | PI3K, phosphoinositide 3-kinase | PTK, protein tyrosine kinase | EGF, epidermal growth factor | TKB, tyrosine-kinase-binding | Review | Sli-1, suppressor of lineage defect-1 | UBA, ubiquitin-associated | WASP, Wiskott–Aldrich syndrome protein | PTB, phosphotyrosine-binding | thymocyte | Ubc, ubiquitin-conjugating | GLUT4, glucose transporter 4 | BMMC, bone-marrow-derived mast cell | KPD, Komeda diabetes-prone | HECT, homologous with E6AP C-terminus | SLAP, Src-like adaptor protein | CIN85, Cbl-interacting protein of 85 kDa | CTLA-4, cytotoxic T-lymphocyte-associated protein 4 | PKC, protein kinase C | ZAP-70, ζ-associated protein of 70 kDa | SLP-76, SH2 domain-containing leucocyte protein of 76 kDa | FcεRI, high-affinity IgE receptor | NFAT, nuclear factor of activated T-cells | GRAIL, gene related to anergy in lymphocytes | RIP-gp, rat insulin promoter glycoprotein | ubiquitin | hSpry2, human Sprouty 2 | RTK, receptor tyrosine kinase | SEM-5, sex muscle abnormal 5 | DP, double positive | LAT, linker for activation of T-cells | APS, adaptor molecule containing pleckstrin homology and Src homology 2 domains | receptor tyrosine kinase | MAIDS, murine AIDS | PDGF, platelet-derived growth factor | BLNK, B-cell linker
Journal Article
PloS one, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0154394 - e0154394
...), is an organ-specific autoimmune disease with a strong genetic component. Although the cytotoxic T-lymphocyte-associated protein 4 (CTLA4... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Haplotypes | Hashimoto Disease - ethnology | Humans | Middle Aged | Child, Preschool | Male | Case-Control Studies | T-Lymphocytes, Cytotoxic - pathology | Graves Disease - genetics | Hashimoto Disease - immunology | Graves Disease - immunology | Adult | Female | Odds Ratio | Child | T-Lymphocytes, Cytotoxic - immunology | Gene Expression | Genetic Predisposition to Disease | Hashimoto Disease - genetics | Graves Disease - ethnology | Gene Frequency | CTLA-4 Antigen - genetics | CTLA-4 Antigen - immunology | Linkage Disequilibrium | Asian Continental Ancestry Group | Adolescent | Alleles | Heterozygote | Aged | Polymorphism, Single Nucleotide | Graves Disease - pathology | Hashimoto Disease - pathology | Genetic aspects | Research | T cells | Genetic polymorphisms | Risk factors | Thyroid diseases | Pediatrics | Physicians | Pathogenesis | Linkage disequilibrium | Genes | Cytotoxicity | Lymphocytes T | Single-nucleotide polymorphism | Gene polymorphism | Proteins | Confidence intervals | CTLA-4 protein | Lymphocytes | Children | Genotypes | Thyroid | Medical research | Antigens | T cell receptors | Metabolism | Disease control | Patients | Community colleges | Medicine | Hospitals | Gene frequency | Adults | Endocrinology | Polymorphism | Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 06/2018, Volume 558, Issue 7710, pp. 454 - 459
...). Here, using RNA and protein expression profiling at single-cell resolution in mouse cells, we identify a module of co-inhibitory receptors that includes not only several known co-inhibitory receptors... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | CD8-Positive T-Lymphocytes - cytology | Male | CD4-Positive T-Lymphocytes - immunology | Immune Tolerance - immunology | Melanoma - genetics | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Transcription, Genetic | Lymphocytes, Tumor-Infiltrating - cytology | Reproducibility of Results | Gene Regulatory Networks - genetics | Interleukin-27 - immunology | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Receptors, Cell Surface - metabolism | Positive Regulatory Domain I-Binding Factor 1 - metabolism | Mice, Knockout | Animals | Melanoma - immunology | Immune Tolerance - genetics | Proto-Oncogene Proteins c-maf - metabolism | Mice | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Receptors, Cell Surface - genetics | Genetic aspects | Genetic transcription | Observations | T cells | Transcription factors | PD-1 protein | CD8 antigen | Gene regulation | Homeostasis | Effector cells | Lymphocytes T | Genomes | CD223 antigen | Immunity | Interleukin 27 | Proteins | Receptors | CTLA-4 protein | Lymphocytes | Bioinformatics | Cytokines | Immunoregulation | Melanoma | Protein C | c-Maf protein | Activated protein C | Gene expression | Ribonucleic acid--RNA | Molecular chains | CD4 antigen | Exhaustion | Computer applications | Receptor mechanisms | Bayesian analysis | Tumors | Index Medicus
Journal Article
Journal Article
Clinical cancer research, ISSN 1557-3265, 08/2017, Volume 23, Issue 15, pp. 4242 - 4250
Journal Article