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ctla-4-deficient mice (66) 66
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Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2006, Volume 103, Issue 44, pp. 16400 - 16405
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2009, Volume 182, Issue 1, pp. 274 - 282
The CTLA-4 pathway is recognized as a major immune inhibitory axis and is a key therapeutic target for augmenting antitumor immunity or curbing autoimmunity.... 
INTESTINAL INFLAMMATION | ANTIGEN 4 | ACTIVATION | TGF-BETA | LYMPHOPROLIFERATIVE DISEASE | IN-VIVO | IMMUNOLOGICAL SELF-TOLERANCE | CTLA-4-DEFICIENT MICE | IMMUNOLOGY | BLOCKADE | EXPRESSION | T-Lymphocytes, Regulatory - metabolism | Cell Proliferation | Lymphoproliferative Disorders - immunology | Antigens, CD - genetics | T-Lymphocytes, Regulatory - pathology | Antigens, CD - metabolism | Receptors, Antigen, T-Cell - biosynthesis | T-Lymphocytes, Regulatory - immunology | Autoimmune Diseases - genetics | Cell Differentiation - genetics | Signal Transduction - immunology | Islets of Langerhans - metabolism | Immunosuppressive Agents - metabolism | Diabetes Mellitus, Type 1 - immunology | Autoimmune Diseases - pathology | Forkhead Transcription Factors - biosynthesis | Islets of Langerhans - pathology | Diabetes Mellitus, Type 1 - pathology | Diabetes Mellitus, Type 1 - genetics | Homeostasis - immunology | Islets of Langerhans - immunology | Autoimmune Diseases - prevention & control | Mice, Transgenic | Lymphoproliferative Disorders - genetics | Signal Transduction - genetics | Forkhead Transcription Factors - genetics | Mice, Knockout | CTLA-4 Antigen | Cell Differentiation - immunology | Lymphoproliferative Disorders - mortality | Animals | Antigens, CD - physiology | Mice | Mice, Inbred BALB C | Receptors, Antigen, T-Cell - genetics | Homeostasis - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Blood, ISSN 0006-4971, 08/2007, Volume 110, Issue 4, pp. 1199 - 1206
Journal Article
The Journal of Immunology, ISSN 0022-1767, 07/2006, Volume 177, Issue 2, pp. 1052 - 1061
CTLA-4 has been shown to be an important negative regulator of T cell activation. To better understand its inhibitory action, we constructed CTLA-4 transgenic... 
ANTIGEN 4 | TYROSINE PHOSPHORYLATION | REGULATORY CELLS | IN-VIVO | INDOLEAMINE 2,3-DIOXYGENASE | SURFACE EXPRESSION | CTLA-4-DEFICIENT MICE | IMMUNOLOGY | CLATHRIN-ASSOCIATED PROTEIN | IMMUNOLOGICAL SYNAPSE | CD28 COSTIMULATION | T-Lymphocyte Subsets - immunology | T-Lymphocyte Subsets - cytology | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Epitopes, T-Lymphocyte - genetics | CD28 Antigens - metabolism | Cell Differentiation - genetics | Signal Transduction - immunology | Lymphocyte Activation - genetics | Mice, Inbred CBA | Encephalomyelitis, Autoimmune, Experimental - genetics | Epitopes, T-Lymphocyte - immunology | Binding, Competitive - immunology | CD28 Antigens - physiology | Mice, Inbred C57BL | Cells, Cultured | B7-1 Antigen - physiology | Lymph Nodes - metabolism | Mice, Transgenic | B7-1 Antigen - metabolism | Signal Transduction - genetics | Lymph Nodes - immunology | Lymph Nodes - cytology | Down-Regulation - genetics | Antigens, Differentiation - physiology | Mice, Knockout | CTLA-4 Antigen | Cell Differentiation - immunology | Antigens, Differentiation - biosynthesis | Animals | Resting Phase, Cell Cycle - genetics | Down-Regulation - immunology | T-Lymphocyte Subsets - metabolism | Resting Phase, Cell Cycle - immunology | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Binding, Competitive - genetics | Antigens, Differentiation - genetics | Mice | Antigens, CD | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2004, Volume 172, Issue 9, pp. 5450 - 5455
Journal Article