X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (115405) 115405
Book Chapter (395) 395
Dissertation (105) 105
Magazine Article (40) 40
Publication (36) 36
Conference Proceeding (32) 32
Book / eBook (25) 25
Newspaper Article (15) 15
Book Review (7) 7
Reference (7) 7
Web Resource (6) 6
Streaming Video (5) 5
Government Document (3) 3
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (75973) 75973
cyclic amp - metabolism (39226) 39226
humans (37397) 37397
rats (31945) 31945
male (27804) 27804
biochemistry & molecular biology (18324) 18324
mice (18200) 18200
female (16611) 16611
phosphorylation (15661) 15661
cells, cultured (14892) 14892
cyclic-amp (13872) 13872
cyclic amp - pharmacology (13719) 13719
cyclic amp (13429) 13429
cyclic amp-dependent protein kinases - metabolism (12413) 12413
in vitro techniques (11366) 11366
cell biology (11008) 11008
signal transduction (11006) 11006
kinetics (10571) 10571
neurosciences (9954) 9954
cell line (9917) 9917
cyclic amp - physiology (8812) 8812
camp (8759) 8759
expression (8699) 8699
calcium - metabolism (8275) 8275
pharmacology & pharmacy (8103) 8103
molecular sequence data (7820) 7820
adenylyl cyclases - metabolism (7800) 7800
colforsin - pharmacology (7666) 7666
dose-response relationship, drug (7659) 7659
endocrinology & metabolism (7136) 7136
activation (7123) 7123
time factors (7003) 7003
cyclic amp response element-binding protein - metabolism (6628) 6628
cyclic amp - biosynthesis (6423) 6423
physiology (6229) 6229
rats, sprague-dawley (6058) 6058
proteins (5942) 5942
cells (5633) 5633
amino acid sequence (5529) 5529
isoproterenol - pharmacology (5309) 5309
base sequence (5059) 5059
protein binding (4995) 4995
gene expression (4827) 4827
research article (4767) 4767
protein kinases - metabolism (4627) 4627
signal transduction - drug effects (4627) 4627
enzyme activation (4612) 4612
adult (4572) 4572
transfection (4535) 4535
bucladesine - pharmacology (4403) 4403
calcium (4274) 4274
enzyme inhibitors - pharmacology (4262) 4262
research (4253) 4253
mutation (4193) 4193
cattle (4180) 4180
binding sites (4172) 4172
signal transduction - physiology (4137) 4137
rats, wistar (4117) 4117
gene-expression (4107) 4107
rabbits (4019) 4019
rats, inbred strains (4015) 4015
cyclic gmp - metabolism (4011) 4011
rna, messenger - metabolism (3905) 3905
multidisciplinary sciences (3783) 3783
inhibition (3767) 3767
physiological aspects (3741) 3741
protein kinase a (3657) 3657
tumor cells, cultured (3460) 3460
receptors (3428) 3428
protein kinase c - metabolism (3413) 3413
kinases (3315) 3315
receptor (3272) 3272
middle aged (3254) 3254
biophysics (3231) 3231
1-methyl-3-isobutylxanthine - pharmacology (3198) 3198
protein (3186) 3186
binding (3155) 3155
cyclic amp-dependent protein kinases - antagonists & inhibitors (3153) 3153
analysis (3095) 3095
mice, inbred c57bl (3094) 3094
enzyme activation - drug effects (3087) 3087
cyclic amp - analysis (3059) 3059
theophylline - pharmacology (3036) 3036
adenylate-cyclase (2995) 2995
brain (2983) 2983
blotting, western (2968) 2968
transcription, genetic (2966) 2966
neurons (2958) 2958
dependent protein-kinase (2902) 2902
3',5'-cyclic-amp phosphodiesterases - metabolism (2893) 2893
promoter regions, genetic (2886) 2886
cricetinae (2877) 2877
gene expression regulation (2862) 2862
models, biological (2850) 2850
cyclic amp response element-binding protein (2848) 2848
identification (2838) 2838
rat (2769) 2769
transcription (2744) 2744
cell membrane - metabolism (2726) 2726
gene (2722) 2722
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (111828) 111828
Japanese (2195) 2195
Russian (1590) 1590
Chinese (630) 630
French (592) 592
German (480) 480
Italian (175) 175
Polish (157) 157
Spanish (155) 155
Czech (41) 41
Ukrainian (32) 32
Portuguese (28) 28
Bulgarian (21) 21
Danish (17) 17
Slovak (17) 17
Dutch (16) 16
Swedish (15) 15
Hungarian (14) 14
Hebrew (13) 13
Korean (13) 13
Norwegian (12) 12
Romanian (9) 9
Finnish (8) 8
Croatian (4) 4
Serbian (3) 3
Afrikaans (2) 2
Turkish (2) 2
Greek (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5680 - 5680
We recently identified a high prevalence of mutations affecting the catalytic (C alpha) subunit of protein kinase A (PKA) in cortisol-secreting adrenocortical... 
CYCLASE | CYCLIC-AMP | MCCUNE-ALBRIGHT SYNDROME | HOLOENZYME | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | ADRENAL-TUMORS | PHOSPHODIESTERASE | HYPERPLASIA | SOMATIC MUTATIONS | CAMP | Adrenocortical Adenoma - enzymology | Humans | Cyclic AMP-Dependent Protein Kinases - chemistry | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - chemistry | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - genetics | Cyclic AMP-Dependent Protein Kinase Catalytic Subunits - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | Cushing Syndrome - enzymology | Cushing Syndrome - pathology | Adrenocortical Adenoma - genetics | Protein Stability | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - metabolism | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - chemistry | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Adrenal Cortex Neoplasms - enzymology | Catalytic Domain | Cushing Syndrome - genetics | Adrenal Cortex Neoplasms - pathology | Adrenocortical Adenoma - pathology | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - genetics | Adrenal Cortex Neoplasms - genetics | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - chemistry | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - genetics | Cell Line, Tumor | Protein Binding | Mutation | Index Medicus
Journal Article
PLoS Biology, ISSN 1544-9173, 11/2015, Volume 13, Issue 11, p. e1002305
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e46216
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 08/2019, Volume 116, Issue 33, pp. 16347 - 16356
Protein kinase A (PKA) holoenzyme, comprised of a cAMP-binding regulatory (R)-subunit dimer and 2 catalytic (C)-subunits, is the master switch for... 
CATALYTIC SUBUNIT | isoform-specific quaternary structure | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | DEPENDENT PROTEIN-KINASE | cAMP | STRUCTURE REVEALS | TARGETED DISRUPTION | I-ALPHA | allosteric and orthosteric regulation | SITE MUTATIONS DEFINE | structural biology | A REGULATORY SUBUNIT | protein kinase A | BETA-SUBUNIT | BINDING | Allosteric Regulation - genetics | Protein Binding - genetics | Humans | Cyclic AMP-Dependent Protein Kinases - chemistry | Adenosine Triphosphate - genetics | Crystallography, X-Ray | Holoenzymes - chemistry | Signal Transduction - genetics | Amino Acid Sequence - genetics | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - genetics | Cyclic AMP - chemistry | Cyclic AMP-Dependent Protein Kinases - genetics | Cyclic AMP-Dependent Protein Kinase RIIbeta Subunit - chemistry | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - genetics | Gene Expression Regulation, Enzymologic - genetics | Protein Structure, Quaternary | Cyclic AMP - genetics | Holoenzymes - genetics | Protein Subunits - chemistry | Adenosine Triphosphate - chemistry | Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - chemistry | Protein Subunits - genetics | Protein kinase A | Crosstalk | Cyclic AMP | Activation | Kinases | Substrates | Interfaces | Allosteric properties | Isoforms | Dimers | Catalysis | Magnesium | ATP | Biological Sciences | PNAS Plus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 08/2007, Volume 27, Issue 35, pp. 9513 - 9524
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 01/2007, Volume 292, Issue 1, pp. 319 - 331
We have previously used cyclic nucleotide-gated (CNG) channels as sensors to measure cAMP signals in human embryonic kidney (HEK)-293 cells. We found that... 
Protein kinase A | CNG channel | A-kinase anchoring protein | G protein signaling | Phosphodiesterase | PHYSIOLOGY | ANCHORING PROTEINS | CARDIAC MYOCYTES | DEPENDENT PROTEIN-KINASE | RESONANCE ENERGY-TRANSFER | EPAC ACTIVATION | VENTRICULAR MYOCYTES | CELL BIOLOGY | CYCLIC-AMP | PHOSPHODIESTERASE PDE4D | ADENYLYL-CYCLASE | phosphodiesterase | protein kinase A | NUCLEOTIDE-GATED CHANNELS | Cyclic AMP-Dependent Protein Kinases - metabolism | Nucleotides, Cyclic - metabolism | 3',5'-Cyclic-AMP Phosphodiesterases - metabolism | Cell Line | Cyclic Nucleotide Phosphodiesterases, Type 4 | Signal Transduction | Prostaglandins - pharmacology | Humans | Phosphodiesterase Inhibitors - pharmacology | Adenylyl Cyclases - metabolism | Sulfonamides - pharmacology | Peptides - pharmacology | Isoquinolines - pharmacology | Ion Channels - metabolism | Adaptor Proteins, Signal Transducing - antagonists & inhibitors | Models, Biological | Computer Simulation | Cell Membrane - metabolism | Protein Kinase Inhibitors - pharmacology | Kinetics | Buffers | Rolipram - pharmacology | Cyclic AMP - metabolism | Ion Channel Gating | Cell Membrane | Ion Channels | Peptides | Isoquinolines | Life Sciences | Prostaglandins | Cyclic AMP-Dependent Protein Kinases | Phosphodiesterase Inhibitors | Adenylate Cyclase | Cyclic AMP | 3',5'-Cyclic-AMP Phosphodiesterases | Nucleotides, Cyclic | Human health and pathology | Adaptor Proteins, Signal Transducing | Protein Kinase Inhibitors | Rolipram | Sulfonamides | Urology and Nephrology
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2014, Volume 370, Issue 11, pp. 1019 - 1028
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2017, Volume 356, Issue 6344, pp. 1288 - 1293
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 8, p. e12322
Background: In rodents, the development of dyskinesia produced by L-DOPA in the dopamine-depleted striatum occurs in response to increased dopamine D1... 
HEMIPARKINSONIAN MICE | LEVODOPA-INDUCED DYSKINESIA | PHOSPHORYLATION | BIOLOGY | MEDIUM SPINY NEURONS | PARKINSONS-DISEASE | SUBUNIT | Cyclic AMP-Dependent Protein Kinases - metabolism | Levodopa - pharmacology | Dyskinesias - pathology | ras Proteins - metabolism | Macaca mulatta | Parkinsonian Disorders - chemically induced | Dyskinesias - etiology | Extracellular Signal-Regulated MAP Kinases - metabolism | Dopamine and cAMP-Regulated Phosphoprotein 32 - metabolism | Dyskinesias - metabolism | Parkinsonian Disorders - metabolism | Animals | MAP Kinase Signaling System - drug effects | Parkinsonian Disorders - pathology | Female | Cyclic AMP - metabolism | Primates | Phenols | Cyclic adenylic acid | Protein kinases | Analysis | Movement disorders | Protein kinase A | Phosphorylation | Neurosciences | Basal ganglia | Parkinson's disease | Glutamic acid receptors (ionotropic) | Parkinsons disease | Monkeys | Kinases | Phosphatase | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors | Proteins | Signal transduction | α-Amino-3-hydroxy-5-methyl-4-isoxazole propionic acid | Rodents | Cascades | Neostriatum | Levodopa | Dyskinesia | Dihydroxyphenylalanine | Dopamine | Neurodegenerative diseases | Animal sciences | Extracellular signal-regulated kinase | Cyclic AMP | Central nervous system diseases | Priming | Ribosomal protein S6 | Monkeys & apes | Signaling | Dopamine D1 receptors | DARPP-32 protein | Dopa | Laboratory animals | Parkinsonian Disorders | Dyskinesias | ras Proteins | Biochemistry, Molecular Biology | Extracellular Signal-Regulated MAP Kinases | MAP Kinase Signaling System | Dopamine and cAMP-Regulated Phosphoprotein 32 | Life Sciences | Cyclic AMP-Dependent Protein Kinases
Journal Article