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Current Topics in Medicinal Chemistry, ISSN 1568-0266, 2013, Volume 13, Issue 6, pp. 821 - 836
Journal Article
Biopolymers - Peptide Science Section, ISSN 0006-3525, 03/2014, Volume 102, Issue 2, pp. 168 - 175
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2012, Volume 18, Issue 3, pp. 4242 - 4253
Journal Article
Chemical Communications: Chem Comm, ISSN 1359-7345, 01/2015, Volume 51, Issue 13, pp. 2510 - 2513
Total synthesis of the cyanobacterial metabolite largamide B and the disproval of its originally assigned stereochemistry as well as confirmation of the... 
Metabolites | Synthesis | Stereochemistry
Journal Article
New Journal of Chemistry, ISSN 1144-0546, 2018, Volume 42, Issue 24, pp. 19779 - 19784
Two novel chiral cyclic peptide analogues of galaxamide were synthesized by photoinduced single electron transfer cyclization. Their stereochemistry was... 
PEPTIDE MIMETICS | PHOTOCHEMISTRY | DESIGN | PHOTOCYCLIZATION | CHEMISTRY, MULTIDISCIPLINARY | CYCLIC-PEPTIDES
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 10/2017, Volume 23, Issue 60, p. n/a
The most common strategies to disulfide bond mimetics are dissected and emerging approaches presented. Functional and synthetic aspects towards disulfide... 
cyclic peptides | peptidomimetics | protein folding | disulfide isosters | drug discovery | Bonds | Drug discovery
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 2017, Volume 15, Issue 2, pp. 459 - 464
Cell penetration and nucleus translocation efficiency are important for the cellular activities of peptide therapeutics. For helical peptides stabilized by... 
CHEMISTRY, ORGANIC | STAPLED PEPTIDES | INHIBITORS | CYCLIC-PEPTIDES | PRINCIPLES | Index Medicus
Journal Article
Chemical Science, ISSN 2041-6520, 12/2014, Volume 6, Issue 1, pp. 3 - 49
A noticeable increase in molecular complexity of drug targets has created an unmet need in the therapeutic agents that are larger than traditional small... 
ASYMMETRIC CATALYSIS | PASSIVE MEMBRANE-PERMEABILITY | CYCLOSPORINE-A | PROTEIN | HELICAL PEPTIDES | STRUCTURAL-CHARACTERIZATION | LINEAR PEPTIDES | SCAFFOLDS | N-METHYLATION | CHEMISTRY, MULTIDISCIPLINARY | CYCLIC-PEPTIDES | Drugs | Cellular | Macrocyclic compounds | Peptides | Historic | Permeability | Bioavailability | Cyclic compounds | Readers | Chemistry
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 04/2017, Volume 23, Issue 24, pp. 5854 - 5854
Griselimycin (GM) and methylgriselimycin (MGM) are cyclic depsipeptides that inhibit the sliding clamp of DNA polymerase III of Mycobacterium tuberculosis and... 
cyclic peptides | antibacterials | methylgriselimycin | structure determination | griselimycin | NMR spectroscopy | Tuberculosis
Journal Article
Chemistry – A European Journal, ISSN 0947-6539, 03/2017, Volume 23, Issue 13, pp. 2970 - 2970
Cyclopropane tethers with three‐dimensional structural diversity are able to remarkably change the conformation and physicochemical properties of cyclic... 
cell permeability | cyclic peptides | conformation analysis | cyclopropane | NMR spectroscopy | Permeability
Journal Article
JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 1665 - 1672
Macrocyclic peptides are considered large enough to inhibit"undruggable" targets, but the design of passively cell-permeable molecules in this space remains a... 
BARRIER DOMAIN | ESTIMATE SOLUBILITY | CHEMISTRY, MEDICINAL | LIPID-BILAYER-MEMBRANES | PERMEABILITY | ARTIFICIAL MEMBRANES | NATURAL-PRODUCTS | MACROCYCLES | DEVELOPMENT SETTINGS | CYCLIC-PEPTIDES | DISCOVERY
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 08/2019, Volume 141, Issue 31, pp. 12274 - 12279
Cyclic peptides are drawing wide attention as potential medium-sized modulators of biomolecular interactions with large binding surfaces. Simple but effective... 
THIOLS | PRIMARY AMINES | ORTHO-PHTHALALDEHYDE | CHEMISTRY, MULTIDISCIPLINARY | CYCLIC-PEPTIDES | MACROCYCLIZATION
Journal Article
Nature Communications, ISSN 2041-1723, 05/2015, Volume 6, Issue 1, p. 7160
Natural peptides show high degrees of specificity in their biological action. However, their therapeutical profile is severely limited by their conformational... 
MILD | FUNCTIONALIZATION | ROOM-TEMPERATURE | PALLADIUM | DESIGN | DIRECT ARYLATION | AMINO-ACIDS | MULTIDISCIPLINARY SCIENCES | BIARYL | SELECTIVITY | CYCLIC-PEPTIDES | Amino Acids - chemistry | Chemistry Techniques, Synthetic | Peptides - chemical synthesis
Journal Article
ChemBioChem, ISSN 1439-4227, 07/2017, Volume 18, Issue 14, pp. 1348 - 1348
The cover picture shows a cyclotide, a globular microprotein with a unique head‐to‐tail cyclized backbone that is stabilized by three disulfide bonds forming a... 
cyclic peptides | imaging agents | cystine knots | drug design | cyclotides
Journal Article