Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (77850) 77850
Publication (10837) 10837
Newspaper Article (3089) 3089
Book Chapter (556) 556
Book Review (459) 459
Dissertation (353) 353
Web Resource (256) 256
Conference Proceeding (122) 122
Government Document (98) 98
Trade Publication Article (83) 83
Magazine Article (48) 48
Newsletter (38) 38
Reference (20) 20
Book / eBook (16) 16
Report (6) 6
Paper (5) 5
Data Set (4) 4
Streaming Video (3) 3
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (46519) 46519
index medicus (29312) 29312
animals (27499) 27499
cell cycle (19683) 19683
oncology (18034) 18034
female (17469) 17469
cell biology (15791) 15791
mice (15612) 15612
apoptosis (14190) 14190
biochemistry & molecular biology (14063) 14063
male (13801) 13801
expression (13778) 13778
cancer (13396) 13396
phosphorylation (12879) 12879
cyclin-dependent kinases (11895) 11895
cell line, tumor (10861) 10861
proteins (10821) 10821
cyclin d1 (10747) 10747
cell proliferation (9266) 9266
kinases (8895) 8895
gene expression (8553) 8553
middle aged (8287) 8287
research (7450) 7450
immunohistochemistry (7280) 7280
signal transduction (7070) 7070
adult (6725) 6725
aged (6674) 6674
cyclin-dependent kinase inhibitor p21 (6559) 6559
proliferation (6241) 6241
cyclins - metabolism (6180) 6180
activation (6007) 6007
mutation (5791) 5791
p53 (5589) 5589
cells, cultured (5582) 5582
tumors (5430) 5430
cyclin d1 - metabolism (5410) 5410
cell line (5217) 5217
protein (5190) 5190
cyclin-dependent kinases - metabolism (5184) 5184
genetic aspects (5090) 5090
apoptosis - drug effects (5065) 5065
cell proliferation - drug effects (5049) 5049
tumor suppressor protein p53 - metabolism (5022) 5022
analysis (5016) 5016
gene expression regulation, neoplastic (4951) 4951
growth (4897) 4897
rats (4896) 4896
article (4895) 4895
tumor cells, cultured (4706) 4706
cell-cycle (4623) 4623
prognosis (4584) 4584
molecular sequence data (4581) 4581
gene (4550) 4550
blotting, western (4518) 4518
cyclins - genetics (4508) 4508
research article (4481) 4481
cyclin-dependent kinase inhibitor p21 - metabolism (4436) 4436
cell growth (4424) 4424
genetics & heredity (4408) 4408
cell division (4379) 4379
cell cycle proteins - metabolism (4363) 4363
breast cancer (4261) 4261
multidisciplinary sciences (4199) 4199
gene-expression (4125) 4125
transfection (4067) 4067
cell cycle - drug effects (4045) 4045
genes (3943) 3943
pathology (3928) 3928
biology (3895) 3895
p21 (3845) 3845
cyclin d1 - genetics (3802) 3802
cells (3773) 3773
down-regulation (3674) 3674
protein binding (3540) 3540
differentiation (3533) 3533
inhibition (3511) 3511
flow cytometry (3501) 3501
physiological aspects (3435) 3435
antineoplastic agents - pharmacology (3421) 3421
cyclin-dependent kinase inhibitor p27 (3408) 3408
medicine (3371) 3371
base sequence (3356) 3356
cyclin-dependent kinase inhibitor p16 - genetics (3339) 3339
amino acid sequence (3306) 3306
mitosis (3296) 3296
cyclins (3263) 3263
health aspects (3250) 3250
rna, messenger - metabolism (3203) 3203
time factors (3186) 3186
cyclin-dependent kinase (3171) 3171
cell cycle - physiology (3148) 3148
in-vivo (3123) 3123
protein-serine-threonine kinases - metabolism (3104) 3104
aged, 80 and over (3066) 3066
p27 (3022) 3022
tumor suppressor protein p53 - genetics (2987) 2987
reverse transcriptase polymerase chain reaction (2979) 2979
carcinoma (2962) 2962
metastasis (2952) 2952
transcription (2949) 2949
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (15) 15
Gerstein Science - Stacks (7) 7
Collection Dvlpm't (Acquisitions) - Vendor file (3) 3
Chemistry (A D Allen) - Stacks (1) 1
Earth Sciences (Noranda) - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (79295) 79295
Chinese (1391) 1391
German (608) 608
Japanese (312) 312
French (203) 203
Russian (108) 108
Korean (101) 101
Spanish (63) 63
Polish (54) 54
Portuguese (21) 21
Czech (20) 20
Turkish (14) 14
Hungarian (9) 9
Italian (8) 8
Slovak (5) 5
Swedish (5) 5
Ukrainian (5) 5
Bulgarian (4) 4
Croatian (3) 3
Romanian (3) 3
Serbian (3) 3
Danish (2) 2
Dutch (2) 2
Finnish (2) 2
Hebrew (2) 2
Persian (2) 2
Catalan (1) 1
Norwegian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Amniotic membrane‐derived cells inhibit proliferation of cancer cell lines by inducing cell cycle arrest
by Magatti, Marta and Munari, Silvia and Vertua, Elsa and Parolini, Ornella
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 09/2012, Volume 16, Issue 9, pp. 2208 - 2218
Cells derived from the amniotic foetal membrane of human term placenta have drawn particular attention mainly for their plasticity and immunological... 
placenta | mesenchymal stem/stromal cells | cancer cell lines | cell proliferation | amniotic membrane | amnion‐derived cells | Cell proliferation | Amniotic membrane | Placenta | Amnion-derived cells | Cancer cell lines | Mesenchymal stem/stromal cells | MEDICINE, RESEARCH & EXPERIMENTAL | amnion-derived cells | TUMOR-CELLS | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | TERM PLACENTA | THERAPY | mesenchymal stem | stromal cells | IN-VIVO | GROWTH | BONE | DIFFERENTIATION | T-CELLS | Cyclin D2 - genetics | Oncogene Proteins - genetics | Up-Regulation | Cyclin D2 - metabolism | Coculture Techniques | Cyclin-Dependent Kinase 4 - genetics | Humans | G1 Phase - drug effects | RNA, Messenger - metabolism | Cyclin E - genetics | Amnion - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Cyclin-Dependent Kinase Inhibitor p15 - genetics | U937 Cells | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Cyclin-Dependent Kinase 2 - metabolism | Amnion - cytology | Down-Regulation | RNA, Messenger - genetics | Cyclin-Dependent Kinase 6 - genetics | Oncogene Proteins - metabolism | Cyclin-Dependent Kinase 2 - genetics | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Cell Division - drug effects | Cyclin H - metabolism | Cell Cycle Checkpoints - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Cyclin E - metabolism | Cyclin-Dependent Kinase Inhibitor p15 - metabolism | HeLa Cells | Cyclin H - genetics | RNA | Dendritic cells | Oncology, Experimental | Cell cycle | Stem cells | Research | Gene expression | Cancer | Biotechnology | Mesenchyme | Leukemia | Metastasis | Kinases | Experiments | Cyclin-dependent kinase 4 | Cyclin D2 | Cell growth | Immunology | Lymphocytes | Penicillin | Fibroblasts | G1 phase | Therapeutic applications | Tumor cell lines | Cyclins | Cyclin-dependent kinase 2 | Studies | Monocytes | Biopsy | S phase | Cell lines | Lymphomas | Apoptosis | Tumors | Original
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo
by Odajima, Junko and Saini, Siddharth and Jung, Piotr and Ndassa-Colday, Yasmine and Ficaro, Scott and Geng, Yan and Marco, Eugenio and Michowski, Wojciech and Wang, Yaoyu E and DeCaprio, James A and Litovchick, Larisa and Marto, Jarrod and Sicinski, Piotr
PLoS Genetics, ISSN 1553-7390, 11/2016, Volume 12, Issue 11, p. e1006429
E-type cyclins (cyclins E1 and E2) are components of the cell cycle machinery that has been conserved from yeast to humans. The major function of E-type... 
SPERMATOGENESIS | MALE MEIOSIS | A-MYB | CDK2 | GENETICS & HEREDITY | HISTONE GENE-TRANSCRIPTION | MICE | SENESCENCE | CDK2-DEPENDENT PHOSPHORYLATION | DEPENDENT KINASES | P300 COACTIVATOR | Cell Cycle - genetics | Cyclin-Dependent Kinase 2 - metabolism | Oncogene Proteins - genetics | Cell Proliferation - genetics | Phosphorylation | Testis - metabolism | Spermatogenesis - genetics | Humans | Cyclins - genetics | Oncogene Proteins - metabolism | Cyclin-Dependent Kinase 2 - genetics | Male | Cyclin E - genetics | S Phase - genetics | Animals | Cyclins - metabolism | Protein Interaction Maps - genetics | Proteomics | Mice | Cyclin E - metabolism | Physiological aspects | Methods | Cyclins | Brain | Peptides | Ontology | Internal medicine | Cyclin-dependent kinases | Genes | Cell division | Biology | Pharmacology | Kinases | Medical schools | Proteins | Cell cycle | Stem cells | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling
by Barzegar, Mansoureh and Ma, Shuang and Zhang, Chao and Chen, Xin and Gu, Ying and Shang, Chaowei and Jiang, Xiaojuan and Yang, Jiao and Nathan, Cherie-Ann and Yang, Shengyong and Huang, Shile
British Journal of Cancer, ISSN 0007-0920, 10/2017, Volume 117, Issue 8, pp. 1154 - 1163
Background: Overexpression of epidermal growth factor receptor (EGFR) occurs in approximately 90% of head and neck squamous cell carcinoma (HNSCC), and is... 
Erk1/2 | MAMMALIAN TARGET | ACTIVATION | head and neck cancer | cell proliferation | PHOSPHORYLATION | apoptosis | PHASE-II | Akt | SKLB188 | P53 | LUNG-CANCER | ONCOLOGY | RESISTANCE | EGF receptor | THERAPIES | MUTATIONS | PROGRESSION | Cyclin D1 - drug effects | Immunohistochemistry | Cyclin D1 - metabolism | Up-Regulation | Cyclin-Dependent Kinase Inhibitor p21 - drug effects | Apoptosis - drug effects | Carcinoma, Squamous Cell - metabolism | Humans | cdc25 Phosphatases - drug effects | Head and Neck Neoplasms - metabolism | Cyclin-Dependent Kinase 4 - drug effects | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Squamous Cell Carcinoma of Head and Neck | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | cdc25 Phosphatases - metabolism | In Situ Nick-End Labeling | Cyclin-Dependent Kinase 2 - metabolism | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Signal Transduction | Purines - pharmacology | Cyclin A - metabolism | Down-Regulation | Cyclin-Dependent Kinase 4 - metabolism | Blotting, Western | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cyclin-Dependent Kinase 2 - drug effects | Cell Proliferation - drug effects | Cyclin A - drug effects | Mice | Molecular Docking Simulation | G1 Phase Cell Cycle Checkpoints - drug effects | In Vitro Techniques | Cyclin-Dependent Kinase Inhibitor p27 - drug effects | Cell proliferation | Drugs | Phosphorylation | Clinical trials | AKT protein | Hydrophobicity | Kinases | Hydrogen bonding | Western blotting | Molecular docking | Anticancer properties | Cyclin-dependent kinase | Cell growth | Epidermal growth factor | Hydrogen bonds | Xenografts | Cell cycle | Chemical bonds | Libraries | Inhibition | Recombinant | Medical research | Squamous cell carcinoma | Head | Approximation | Epidermal growth factor receptors | Cyclin-dependent kinases | Extracellular signal-regulated kinase | Caspase | Survivin | Cyclins | Mcl-1 protein | Cyclin-dependent kinase 2 | Signaling | Cyclin-dependent kinase inhibitor p21 | Inhibitors | Cyclin-dependent kinase inhibitor p27 | Head and neck cancer | Scaffolds | Tumors | Apoptosis | Translational Therapeutics | Erk1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Cell cycle, CDKs and cancer: a changing paradigm
by Malumbres, Marcos and Barbacid, Mariano
Nature Reviews Cancer, ISSN 1474-175X, 03/2009, Volume 9, Issue 3, pp. 153 - 166
Tumour-associated cell cycle defects are often mediated by alterations in cyclin-dependent kinase (CDK) activity. Misregulated CDKs induce unscheduled... 
WILD-TYPE P53 | BREAST-CANCER | ONCOLOGY | DNA-DAMAGE RESPONSE | PROTEIN-KINASE | HEMATOPOIETIC STEM-CELLS | EMBRYONIC LETHALITY | TUMOR-SUPPRESSOR | DEPENDENT KINASE INHIBITOR | ONCOGENE-INDUCED SENESCENCE | MITOTIC CHECKPOINT | Neoplastic Stem Cells - cytology | Cell Proliferation | Mitosis | Humans | Cyclin E - physiology | Neoplasms - drug therapy | Animals | Cell Cycle | Neoplasms - genetics | Protein Kinase Inhibitors - therapeutic use | Chromosome Aberrations | Cyclins - physiology | Cyclin D | Cyclin-Dependent Kinases - antagonists & inhibitors | DNA Damage | Neoplasms - pathology | Chromosomal Instability | Cyclin-Dependent Kinases - physiology | Care and treatment | Cell cycle | Physiological aspects | Genetic aspects | Research | Protein kinases | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Targeting CDK4 and CDK6: From discovery to therapy
by Sherr, Charles J and Beach, David and Shapiro, Geoffrey I
Cancer Discovery, ISSN 2159-8274, 04/2016, Volume 6, Issue 4, pp. 353 - 367
Biochemical and genetic characterization of D-type cyclins, their cyclin D-dependent kinases (CDK4 and CDK6), and the polypeptide CDK4/6 inhibitor p16(INK4)... 
BREAST-CANCER | DOSE-ESCALATION | DEPENDENT KINASE 4/6 | ONCOLOGY | RETINOBLASTOMA SUSCEPTIBILITY GENE | CELL-CYCLE | ANTITUMOR-ACTIVITY | FEEDBACK INHIBITION | PD 0332991 | PHASE-I | INHIBITOR PALBOCICLIB | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Neoplasms - metabolism | Cell Cycle - genetics | Phosphorylation | Cyclin-Dependent Kinase 4 - genetics | Humans | Neoplasms - diagnosis | Phosphatidylinositol 3-Kinases - metabolism | Molecular Targeted Therapy | Neoplasms - genetics | Gene Expression Regulation, Neoplastic - drug effects | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Cyclin-Dependent Kinase 6 - genetics | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Treatment Outcome | Clinical Trials as Topic | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Drug Discovery | Neoplasms - drug therapy | Animals | Signal Transduction - drug effects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Protein Kinase Inhibitors - therapeutic use | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Protein Kinase Inhibitors - pharmacology | Cell Cycle - drug effects | Cyclin D - genetics | Cyclin D - metabolism | D-type cyclins | cell cycle | p16INK4a | palbociclib | ribociclib | abemaciclib
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways
by Liu, Dawo and Liu, Juanjuan and Lin, Bei and Liu, Shuice and Hou, Rui and Hao, Yingying and Liu, Qing and Zhang, Shulan and Iwamori, Masao
International Journal of Molecular Sciences, ISSN 1422-0067, 2012, Volume 13, Issue 1, pp. 828 - 839
Objective: To investigate the effect of Lewis y overexpression on the expression of proliferation-related factors in ovarian cancer cells. Methods: mRNA levels... 
Cyclin | Cyclin-dependent kinase inhibitors | Lewis(y) antigen | Cyclin-dependent kinases | Cell cycle | PROTEIN-KINASE PATHWAY | ACTIVATION | cyclin | STIMULATION | CANCER CELLS | cell cycle | BIOCHEMISTRY & MOLECULAR BIOLOGY | G1 CYCLIN | CHEMISTRY, MULTIDISCIPLINARY | BETA | cyclin-dependent kinases | GROWTH | S-PHASE | cyclin-dependent kinase inhibitors | INHIBITOR | EXPRESSION | Cyclin D1 - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Ovarian Neoplasms - pathology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Cyclin A - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Cyclin E - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Antibodies - immunology | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Flavonoids - pharmacology | Ovarian Neoplasms - metabolism | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Lewis Blood-Group System - immunology | Cyclin-Dependent Kinase 2 - metabolism | Fucosyltransferases - genetics | Cyclin A - metabolism | Cyclin-Dependent Kinase 6 - genetics | Cyclin-Dependent Kinase 2 - genetics | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Morpholines - pharmacology | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Fucosyltransferases - metabolism | Cyclin D1 - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Lewis Blood-Group System - metabolism | Lewis Blood-Group System - genetics | Cyclin E - metabolism | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Cell proliferation | Galactoside 2- alpha -L-fucosyltransferase | Antibodies | Extracellular signal-regulated kinase | AKT protein | MAP kinase | mRNA | Gene expression | Cyclin-dependent kinase 4 | Western blotting | 1-Phosphatidylinositol 3-kinase | Cyclin-dependent kinase | Polymerase chain reaction | Signal transduction | Transfection | Cyclin A | Cyclin E | cyclin D1
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text CDK1 structures reveal conserved and unique features of the essential cell cycle CDK
by Brown, Nicholas R and Korolchuk, Svitlana and Martin, Mathew P and Stanley, Will A and Moukhametzianov, Rouslan and Noble, Martin E. M and Endicott, Jane A
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6769
CDK1 is the only essential cell cycle CDK in human cells and is required for successful completion of M-phase. It is the founding member of the CDK family and... 
ACTIVATION | COMPLEX | SPECIFICITY | ANAPHASE-PROMOTING COMPLEX/CYCLOSOME | PHOSPHORYLATION | CRYSTAL-STRUCTURE | SUBSTRATE | MULTIDISCIPLINARY SCIENCES | INHIBITORS | DEPENDENT KINASES | INSIGHTS | CDC2 Protein Kinase | Humans | Substrate Specificity | Crystallography, X-Ray | Cyclin A - genetics | Cell Cycle Proteins - chemistry | Protein Kinase Inhibitors - chemistry | Cyclin B - genetics | Peptides - chemical synthesis | Cattle | Cell Cycle Proteins - genetics | Conserved Sequence | Carrier Proteins - chemistry | Cyclin-Dependent Kinases - antagonists & inhibitors | Protein Stability | Cyclin-Dependent Kinases - genetics | Binding, Competitive | Protein Structure, Tertiary | Gene Expression | Cyclin-Dependent Kinases - chemistry | Peptides - chemistry | Protein Structure, Secondary | CDC2-CDC28 Kinases - chemistry | Cyclin-Dependent Kinase 2 - genetics | Models, Molecular | Cyclin-Dependent Kinase 2 - chemistry | Recombinant Fusion Proteins - chemistry | Carrier Proteins - genetics | Animals | Protein Binding | Recombinant Fusion Proteins - genetics | Cyclin B - chemistry | Kinetics | Adenosine Triphosphate - chemistry | CDC2-CDC28 Kinases - genetics | Cyclin A - chemistry | Cyclin-dependent kinase | Cyclin-dependent kinase 2 | Eukaryotes | Cyclin B | Cyclin A | Cell cycle | Dephosphorylation | Thermal stability | Substrates | Nature conservation | Crystal structure | Cancer
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Epithelial cell transforming sequence 2 in human oral cancer
by Iyoda, Manabu and Kasamatsu, Atsushi and Ishigami, Takashi and Nakashima, Dai and Endo-Sakamoto, Yosuke and Ogawara, Katsunori and Shiiba, Masashi and Tanzawa, Hideki and Uzawa, Katsuhiro
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e14082
Background: Epithelial cell transforming sequence 2 (ECT2) is a guanine nucleotide exchange factor for Rho family GTPase, which has been implicated in the... 
CYTOKINESIS REGULATOR ECT2 | OVEREXPRESSION | G2/M PHASE | LYMPH-NODE METASTASIS | MULTIDISCIPLINARY SCIENCES | RHO-GTPASES | G PHASE | CARCINOMA | ABERRANT EXPRESSION | PROGRESSION | CYCLE | Immunohistochemistry | Cyclin D1 - metabolism | Cell Proliferation | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Cyclin-Dependent Kinase 4 - genetics | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Mouth Neoplasms - metabolism | Cyclin E - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Mouth Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - genetics | Cyclin-Dependent Kinase 4 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | G1 Phase | Cell Cycle | Cyclin D1 - genetics | Cell Line, Tumor | Mouth Neoplasms - pathology | Aged | Cyclin E - metabolism | Neoplasm Staging | DNA polymerases | Squamous cell carcinoma | Research | Comparative analysis | Mouth cancer | Cell proliferation | Flow cytometry | RNA-directed DNA polymerase | Oral cancer | Epithelial cells | Metastasis | Cyclin D1 | Kinases | Autophagy | Guanine | Cyclin-dependent kinase 4 | Maxillofacial surgery | Proteins | Cyclin-dependent kinase | Signal transduction | Rodents | Surgery | Cell cycle | Cyclin E | Cyclin-dependent kinase inhibitors | Guanine nucleotide exchange factor | Localization | Kip protein | G1 phase | Evaluation | Oral squamous cell carcinoma | Dentistry | Gene expression | Polymerase chain reaction | Medicine | Cytometry | Cyclin-dependent kinase inhibitor p21 | Cell lines | Cyclin-dependent kinase inhibitor p27 | Protein expression | Molecular biology | Cancer | Guanosinetriphosphatase | Apoptosis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text TEAD4-YAP interaction regulates tumoral growth by controlling cell-cycle arrest at the G1 phase
by Takeuchi, Shin and Kasamatsu, Atsushi and Yamatoji, Masanobu and Nakashima, Dai and Endo-Sakamoto, Yosuke and Koide, Nao and Takahara, Toshikazu and Shimizu, Toshihiro and Iyoda, Manabu and Ogawara, Katsunori and Shiiba, Masashi and Tanzawa, Hideki and Uzawa, Katsuhiro
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 04/2017, Volume 486, Issue 2, pp. 385 - 390
TEA domain transcription factor 4 (TEAD4), which has critical functions in the process of embryonic development, is expressed in various cancers. However, the... 
TEA domain transcription factor 4 | Human oral squamous cell carcinoma | Yes-associated protein (YAP) | TARGET | BIOMARKER | BIOCHEMISTRY & MOLECULAR BIOLOGY | HIPPO PATHWAY | YAP | FAMILY | BIOPHYSICS | DNA | PROGNOSTIC MARKER | EXPRESSION | RNA, Small Interfering - genetics | Cell Proliferation | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Male | Cyclin E - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Cell Nucleus - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Muscle Proteins - antagonists & inhibitors | Transcription, Genetic | Mouth Neoplasms - genetics | Cyclin-Dependent Kinase 2 - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Signal Transduction | Cyclin-Dependent Kinase 2 - genetics | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Muscle Proteins - genetics | Cell Nucleus - genetics | Cyclin D1 - genetics | Mouth Neoplasms - surgery | Cell Line, Tumor | RNA, Small Interfering - metabolism | Cyclin D1 - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Cyclin-Dependent Kinase 4 - genetics | Gene Expression Regulation, Neoplastic | Carcinoma, Squamous Cell - surgery | Mouth Neoplasms - metabolism | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Muscle Proteins - metabolism | G1 Phase Cell Cycle Checkpoints | Female | Cyclin-Dependent Kinase 6 - genetics | Transcription Factors - antagonists & inhibitors | Phosphoproteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Transcription Factors - metabolism | Adaptor Proteins, Signal Transducing - genetics | Mouth Neoplasms - pathology | Aged | Cyclin E - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Immunohistochemistry | Medical colleges | Embryonic development | Squamous cell carcinoma | Growth | Analysis | DNA polymerases | Genetic transcription | Health aspects | Development and progression | TRANSCRIPTION FACTORS | CHAIN REACTIONS | BIOLOGICAL MARKERS | CELL PROLIFERATION | CELL CYCLE | INTERACTIONS | 60 APPLIED LIFE SCIENCES | PLANT GROWTH
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights