Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (69067) 69067
Newspaper Article (4205) 4205
Web Resource (885) 885
Book Chapter (387) 387
Dissertation (326) 326
Government Document (98) 98
Publication (75) 75
Conference Proceeding (59) 59
Magazine Article (50) 50
Newsletter (28) 28
Reference (20) 20
Book / eBook (17) 17
Book Review (14) 14
Trade Publication Article (12) 12
Paper (3) 3
Streaming Video (3) 3
Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (51529) 51529
life sciences & biomedicine (47091) 47091
humans (43057) 43057
animals (24770) 24770
cell cycle (20063) 20063
oncology (16902) 16902
female (16371) 16371
cell biology (14365) 14365
mice (13958) 13958
male (13080) 13080
biological and medical sciences (12977) 12977
biochemistry & molecular biology (11998) 11998
cyclin-dependent kinases (11978) 11978
proteins (11246) 11246
apoptosis (11174) 11174
kinases (10431) 10431
cell line, tumor (10419) 10419
phosphorylation (9786) 9786
cell proliferation (9321) 9321
medical sciences (9284) 9284
tumors (9182) 9182
gene expression (8876) 8876
cancer (8572) 8572
middle aged (7849) 7849
research (6982) 6982
signal transduction (6876) 6876
cyclin-dependent kinase inhibitor p21 (6850) 6850
cyclin d1 (6716) 6716
immunohistochemistry (6602) 6602
adult (6314) 6314
aged (6273) 6273
cyclins - metabolism (6134) 6134
cyclin d1 - metabolism (5567) 5567
mutation (5565) 5565
cyclin-dependent kinases - metabolism (5206) 5206
cells, cultured (5165) 5165
cell proliferation - drug effects (4966) 4966
apoptosis - drug effects (4926) 4926
tumor suppressor protein p53 - metabolism (4901) 4901
cell growth (4893) 4893
cell line (4768) 4768
gene expression regulation, neoplastic (4702) 4702
breast cancer (4683) 4683
analysis (4662) 4662
genetic aspects (4647) 4647
research article (4579) 4579
cyclin-dependent kinase inhibitor p21 - metabolism (4555) 4555
cyclins - genetics (4486) 4486
fundamental and applied biological sciences. psychology (4388) 4388
tumor cells, cultured (4325) 4325
rats (4282) 4282
science & technology - other topics (4281) 4281
cell division (4268) 4268
multidisciplinary sciences (4226) 4226
blotting, western (4096) 4096
cell cycle proteins - metabolism (4011) 4011
cyclin d1 - genetics (3938) 3938
prognosis (3912) 3912
cell cycle - drug effects (3893) 3893
molecular sequence data (3883) 3883
genetics & heredity (3869) 3869
biology (3769) 3769
transfection (3740) 3740
flow cytometry (3647) 3647
cyclin-dependent kinase inhibitor p27 (3512) 3512
genes (3454) 3454
cyclin-dependent kinase inhibitor p16 - genetics (3453) 3453
pathology (3400) 3400
medicine (3336) 3336
antineoplastic agents - pharmacology (3277) 3277
protein binding (3245) 3245
cyclins (3168) 3168
health aspects (3153) 3153
physiological aspects (3003) 3003
cyclin-dependent kinase inhibitor p21 - genetics (2980) 2980
cell cycle - physiology (2975) 2975
rna, messenger - metabolism (2941) 2941
tumor suppressor protein p53 - genetics (2938) 2938
cyclin-dependent kinase inhibitor p16 - metabolism (2914) 2914
cyclin-dependent kinase 2 (2905) 2905
time factors (2896) 2896
protein-serine-threonine kinases - metabolism (2887) 2887
base sequence (2884) 2884
deoxyribonucleic acid--dna (2883) 2883
aged, 80 and over (2854) 2854
medicine, research & experimental (2826) 2826
research & experimental medicine (2821) 2821
amino acid sequence (2809) 2809
dna damage (2788) 2788
cyclin-dependent kinases - antagonists & inhibitors (2766) 2766
polymerase chain reaction (2719) 2719
metastasis (2685) 2685
p53 (2679) 2679
cancer therapies (2666) 2666
gene expression regulation (2652) 2652
cell cycle proteins (2623) 2623
pharmacology & pharmacy (2622) 2622
reverse transcriptase polymerase chain reaction (2609) 2609
science (2601) 2601
cyclin-dependent kinase 4 (2552) 2552
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (15) 15
Gerstein Science - Stacks (7) 7
Collection Dvlpm't (Acquisitions) - Vendor file (3) 3
Chemistry (A D Allen) - Stacks (1) 1
Earth Sciences (Noranda) - Stacks (1) 1
UofT at Mississauga - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (73062) 73062
Chinese (1811) 1811
Japanese (580) 580
German (570) 570
French (177) 177
Russian (129) 129
Portuguese (102) 102
Korean (78) 78
Spanish (63) 63
Polish (49) 49
Czech (22) 22
Turkish (15) 15
Italian (13) 13
Hungarian (9) 9
Norwegian (7) 7
Croatian (5) 5
Dutch (5) 5
Slovak (5) 5
Swedish (5) 5
Ukrainian (5) 5
Bulgarian (4) 4
Danish (4) 4
Romanian (4) 4
Serbian (3) 3
Finnish (2) 2
Hebrew (2) 2
Persian (2) 2
Catalan (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways
by Liu, Dawo and Liu, Juanjuan and Lin, Bei and Liu, Shuice and Hou, Rui and Hao, Yingying and Liu, Qing and Zhang, Shulan and Iwamori, Masao
International journal of molecular sciences, ISSN 1422-0067, 2012, Volume 13, Issue 1, pp. 828 - 839
Cyclin | Cyclin-dependent kinase inhibitors | Lewis(y) antigen | Cyclin-dependent kinases | Cell cycle | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Cyclin D1 - metabolism | Cyclin-Dependent Kinase 4 - genetics | Humans | Ovarian Neoplasms - pathology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Cyclin A - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Cyclin E - genetics | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Antibodies - immunology | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Flavonoids - pharmacology | Ovarian Neoplasms - metabolism | Chromones - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Lewis Blood-Group System - immunology | Cyclin-Dependent Kinase 2 - metabolism | Fucosyltransferases - genetics | Cyclin A - metabolism | Cyclin-Dependent Kinase 6 - genetics | Cyclin-Dependent Kinase 2 - genetics | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Morpholines - pharmacology | Cyclin-Dependent Kinase 6 - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Fucosyltransferases - metabolism | Cyclin D1 - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Lewis Blood-Group System - metabolism | Lewis Blood-Group System - genetics | Cyclin E - metabolism | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Cell proliferation | Galactoside 2- alpha -L-fucosyltransferase | Antibodies | Extracellular signal-regulated kinase | AKT protein | MAP kinase | mRNA | Gene expression | Cyclin-dependent kinase 4 | Western blotting | 1-Phosphatidylinositol 3-kinase | Cyclin-dependent kinase | Polymerase chain reaction | Signal transduction | Transfection | Cyclin A | Cyclin E | cyclin D1 | Index Medicus | cyclin | cyclin-dependent kinases | cyclin-dependent kinase inhibitors | cell cycle
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Cell cycle, CDKs and cancer: a changing paradigm
by Malumbres, Marcos and Barbacid, Mariano
Nature reviews. Cancer, ISSN 1474-175X, 03/2009, Volume 9, Issue 3, pp. 153 - 166
Life Sciences & Biomedicine | Oncology | Science & Technology | Neoplastic Stem Cells - cytology | Cell Proliferation | Mitosis | Humans | Cyclin E - physiology | Neoplasms - drug therapy | Animals | Cell Cycle | Neoplasms - genetics | Protein Kinase Inhibitors - therapeutic use | Chromosome Aberrations | Cyclins - physiology | Cyclin D | Cyclin-Dependent Kinases - antagonists & inhibitors | DNA Damage | Neoplasms - pathology | Chromosomal Instability | Cyclin-Dependent Kinases - physiology | Care and treatment | Cell cycle | Physiological aspects | Genetic aspects | Research | Protein kinases | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Absence of cyclin-dependent kinase inhibitor p27 or p18 increases efficiency of iPSC generation without induction of iPSC genomic instability
by Zhan, Zhiyan and Song, Lili and Zhang, Weiwei and Gu, Haihui and Cheng, Haizi and Zhang, Yingwen and Yang, Yi and Ji, Guangzhen and Feng, Haizhong and Cheng, Tao and Li, Yanxin
Cell death & disease, ISSN 2041-4889, 04/2019, Volume 10, Issue 4, pp. 271 - 271
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Division - genetics | Cyclin-Dependent Kinase Inhibitor p18 - deficiency | Transduction, Genetic | Mice, Inbred C57BL | Mice, SCID | Cyclin-Dependent Kinase Inhibitor p18 - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - deficiency | Mice, Knockout | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Animals | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Chromosome Aberrations | Cyclin-Dependent Kinase 2 - antagonists & inhibitors | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Mice, Inbred NOD | Mice | Cyclin-Dependent Kinase Inhibitor p27 - deficiency | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Cellular Reprogramming - genetics | Genomic Instability - genetics | Cyclin-Dependent Kinase Inhibitor p27 - genetics | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Cyclin-dependent kinases | DNA damage | Stem cell transplantation | Kinases | Cyclin-dependent kinase 4 | Genomic instability | Cyclin-dependent kinase | Cyclin-dependent kinase 2 | Cyclin-dependent kinase inhibitor p21 | Clonal deletion | Efficiency | Stem cells | Cell cycle | Cyclin-dependent kinase inhibitor p27 | Pluripotency | Chromosome aberrations | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling
by Barzegar, Mansoureh and Ma, Shuang and Zhang, Chao and Chen, Xin and Gu, Ying and Shang, Chaowei and Jiang, Xiaojuan and Yang, Jiao and Nathan, Cherie-Ann and Yang, Shengyong and Huang, Shile
British journal of cancer, ISSN 0007-0920, 10/2017, Volume 117, Issue 8, pp. 1154 - 1163
Life Sciences & Biomedicine | Oncology | Science & Technology | Cyclin D1 - drug effects | Immunohistochemistry | Cyclin D1 - metabolism | Up-Regulation | Cyclin-Dependent Kinase Inhibitor p21 - drug effects | Apoptosis - drug effects | Carcinoma, Squamous Cell - metabolism | Humans | cdc25 Phosphatases - drug effects | Head and Neck Neoplasms - metabolism | Cyclin-Dependent Kinase 4 - drug effects | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Squamous Cell Carcinoma of Head and Neck | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | cdc25 Phosphatases - metabolism | In Situ Nick-End Labeling | Cyclin-Dependent Kinase 2 - metabolism | ErbB Receptors - antagonists & inhibitors | ErbB Receptors - metabolism | Signal Transduction | Purines - pharmacology | Cyclin A - metabolism | Down-Regulation | Cyclin-Dependent Kinase 4 - metabolism | Blotting, Western | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Cyclin-Dependent Kinase 2 - drug effects | Cell Proliferation - drug effects | Cyclin A - drug effects | Mice | Molecular Docking Simulation | G1 Phase Cell Cycle Checkpoints - drug effects | In Vitro Techniques | Cyclin-Dependent Kinase Inhibitor p27 - drug effects | Index Medicus | Translational Therapeutics | Erk1 | head and neck cancer | cell proliferation | apoptosis | EGF receptor | Akt | SKLB188
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text CDK1 structures reveal conserved and unique features of the essential cell cycle CDK
by Brown, Nicholas R and Korolchuk, Svitlana and Martin, Mathew P and Stanley, Will A and Moukhametzianov, Rouslan and Noble, Martin E. M and Endicott, Jane A
Nature communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, pp. 6769 - 6769
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | CDC2 Protein Kinase | Humans | Substrate Specificity | Crystallography, X-Ray | Cyclin A - genetics | Cell Cycle Proteins - chemistry | Protein Kinase Inhibitors - chemistry | Cyclin B - genetics | Peptides - chemical synthesis | Cattle | Cell Cycle Proteins - genetics | Conserved Sequence | Carrier Proteins - chemistry | Cyclin-Dependent Kinases - antagonists & inhibitors | Protein Stability | Cyclin-Dependent Kinases - genetics | Binding, Competitive | Protein Structure, Tertiary | Gene Expression | Cyclin-Dependent Kinases - chemistry | Peptides - chemistry | Protein Structure, Secondary | CDC2-CDC28 Kinases - chemistry | Cyclin-Dependent Kinase 2 - genetics | Models, Molecular | Cyclin-Dependent Kinase 2 - chemistry | Recombinant Fusion Proteins - chemistry | Carrier Proteins - genetics | Animals | Protein Binding | Recombinant Fusion Proteins - genetics | Cyclin B - chemistry | Kinetics | Adenosine Triphosphate - chemistry | CDC2-CDC28 Kinases - genetics | Cyclin A - chemistry | Cyclin-dependent kinase | Cyclin-dependent kinase 2 | Eukaryotes | Cyclin B | Cyclin A | Cell cycle | Dephosphorylation | Thermal stability | Substrates | Nature conservation | Crystal structure | Cancer | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition
by Guiley, Keelan Z and Stevenson, Jack W and Lou, Kevin and Barkovich, Krister J and Kumarasamy, Vishnu and Wijeratne, Tilini U and Bunch, Katharine L and Tripathi, Sarvind and Knudsen, Erik S and Witkiewicz, Agnieszka K and Shokat, Kevan M and Rubin, Seth M
Science (American Association for the Advancement of Science), ISSN 0036-8075, 12/2019, Volume 366, Issue 6471, p. 1330
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phosphorylation | Biocatalysis | Allosteric Regulation | Humans | Retinoblastoma Protein - metabolism | Crystallography, X-Ray | Cyclin-Dependent Kinase 4 - metabolism | Piperazines - pharmacology | Cyclin D1 - chemistry | Cyclin-Dependent Kinase Inhibitor p27 - metabolism | Cyclin-Dependent Kinase 4 - chemistry | Cyclin-Dependent Kinase Inhibitor p27 - chemistry | Cell Line, Tumor | Protein Conformation | Antineoplastic Agents - pharmacology | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Enzyme Activation | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Cell proliferation | Low concentrations | Clinical trials | Activation | Kinases | Antiestrogens | Cyclin D1 | Inactivation | Cyclin-dependent kinase 4 | Monomers | Proteins | Cell cycle | Inhibition | Cyclin D | Assembly | Adenosine triphosphate | Crystal structure | Tyrosine | Deactivation | Tumor cells | Cyclin-dependent kinases | Retinoblastoma protein | Breast cancer | Trimers | ErbB-2 protein | Substrates | Cyclin-dependent kinase 2 | Organic chemistry | Cyclin-dependent kinase inhibitor p21 | Inhibitors | Adenosine kinase | Cyclin-dependent kinase inhibitor p27 | Tumor suppressor genes | Retinoblastoma | ATP | Binding sites | Structural analysis | Tumors | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text RAF inhibitor LY3009120 sensitizes RAS or BRAF mutant cancer to CDK4/6 inhibition by abemaciclib via superior inhibition of phospho-RB and suppression of cyclin D1
by Chen, S.-H and Gong, X and Zhang, Y and Van Horn, R.D and Yin, T and Huber, L and Burke, T.F and Manro, J and Iversen, P.W and Wu, W and Bhagwat, S.V and Beckmann, R.P and Tiu, R.V and Buchanan, S.G and Peng, S.-B
Oncogene, ISSN 0950-9232, 02/2018, Volume 37, Issue 6, pp. 821 - 832
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Neoplasms - metabolism | Cyclin D1 - metabolism | Phosphorylation | Cell Proliferation | Proto-Oncogene Proteins p21(ras) - genetics | Cyclin-Dependent Kinase 4 - genetics | Humans | GTP Phosphohydrolases - antagonists & inhibitors | Rats, Nude | Cyclin D1 - antagonists & inhibitors | Neoplasms - genetics | Biomarkers, Tumor - metabolism | Female | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured |