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Toxicology, ISSN 0300-483X, 09/2017, Volume 390, pp. 83 - 87
Journal Article
Journal Article
Reproduction, ISSN 1470-1626, 08/2014, Volume 148, Issue 2, pp. R29 - R40
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 03/2002, Volume 277, Issue 12, pp. 10459 - 10466
Prostaglandin D-2 (PGD(2)), a major cyclooxygenase product in a variety of tissues, readily undergoes dehydration to yield the cyclopentenone-type PGs of the... 
APOPTOSIS | ACTIVATED RECEPTOR-GAMMA | CYCLOPENTENONE PROSTAGLANDINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACROPHAGE | GENE-EXPRESSION | MONOCYTES | PPAR-GAMMA | MECHANISMS | CYCLOOXYGENASE | 9-DEOXY-DELTA-9,DELTA-12-13,14-DIHYDROPROSTAGLANDIN-D2
Journal Article
Russian Journal of Organic Chemistry, ISSN 1070-4280, 11/2018, Volume 54, Issue 11, pp. 1585 - 1629
The review covers the literature on the total synthesis of cross-conjugated cyclopentenone prostaglandins (PGs), published from 2000 until present. In view of... 
Chemistry | Organic Chemistry | PAUSON-KHAND REACTION | 2,4-DISUBSTITUTED CYCLOPENTENONES | PHASE SYNTHESIS | OXIDATIVE STRESS | ASYMMETRIC-SYNTHESIS | BIOLOGICAL-ACTIVITY | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | CHEMISTRY, ORGANIC | DELTA-PROSTAGLANDIN J | HIGHLY POTENT | ENANTIOSELECTIVE TOTAL-SYNTHESIS | Prostaglandins | Synthesis | Organic compounds
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2018, Volume 500, Issue 2, pp. 204 - 210
Recently, the modulation of cellular inflammatory responses via endogenous regulators became a major focus of medically relevant investigations. Prostaglandins... 
C6-glioma cells | Peroxisome proliferator-activated receptor-γ (PPARγ) | Glial cells | Cyclopentenone prostaglandins | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | INDUCTION | CYCLOOXYGENASE | AGONISTS | BETA/DELTA | BIOPHYSICS | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | PPAR-GAMMA | CELL-CYCLE | GROWTH-FACTOR | MEDIATORS | EXPRESSION
Journal Article
Annals of the New York Academy of Sciences, ISSN 0077-8923, 01/2016, Volume 1363, Issue 1, pp. 125 - 137
Prostaglandins (PGs) are produced via cyclooxygenases, which are enzymes that play a major role in neuroinflammation. Epidemiological studies show that chronic... 
Parkinson's disease | NSAID | cyclooxygenases | Alzheimer's diseases | prostaglandin J2 | Michael adducts | chronic inflammation | Chronic inflammation | Prostaglandin J2 | Cyclooxygenases | ACTIVATED RECEPTOR-GAMMA | D SYNTHASE | ALZHEIMERS-DISEASE | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | LIPOCALIN-TYPE | BREAST-CANCER CELLS | NUTRITION & DIETETICS | CYCLOPENTENONE PROSTAGLANDINS | GENE-EXPRESSION | PPAR-GAMMA | PARKINSONS-DISEASE | Alzheimer Disease - etiology | Neurons - pathology | Neurodegenerative Diseases - etiology | Humans | Lipopolysaccharides - metabolism | Parkinson Disease - drug therapy | Neurodegenerative Diseases - drug therapy | Lipopolysaccharides - immunology | Receptors, Prostaglandin - metabolism | Inflammation - complications | Inflammation - metabolism | Prostaglandin D2 - metabolism | Prostaglandin D2 - analogs & derivatives | Neurons - metabolism | Parkinson Disease - metabolism | Disease Models, Animal | Signal Transduction | Alzheimer Disease - drug therapy | Inflammation - immunology | Neurodegenerative Diseases - metabolism | Animals | Alzheimer Disease - metabolism | Protein Binding | Protein Processing, Post-Translational | Parkinson Disease - etiology | Prostaglandins - metabolism | Nervous system diseases | Cysteine | Prostaglandins | Inflammation | Epidemiology | Alzheimer's disease | Protein binding | Prescription drugs | Neurotoxicity | Nonsteroidal anti-inflammatory drugs | Alzheimers disease | Neurodegeneration | Rodents | Enzymes | Side effects | Peptides | Downstream effects | Medical services | Disorders | In vivo methods and tests | Alzheimer's and Parkinson's diseases
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 10/2014, Volume 55, Issue 41, pp. 5622 - 5624
A new approach to 15-deoxy-Δ -prostaglandin J and related structures based on the (±)-Corey lactone diol has been developed. The key stage of this approach... 
PGJ | methyl ester | 15-Deoxy-Δ | Corey lactone | Cyclopentenone prostaglandins | Total synthesis
Journal Article
MOLECULAR PHARMACOLOGY, ISSN 0026-895X, 01/2016, Volume 89, Issue 1, pp. 42 - 52
Aldose reductase (AKR1B1) is a critical drug target because of its involvement in diabetic complications, inflammation, and tumorigenesis. However, to date,... 
OSMOTIC-STRESS | DIABETIC CATARACT | MECHANISM | GENE | CYCLOPENTENONE PROSTAGLANDINS | PROTEIN MODIFICATION | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | PHARMACOLOGY & PHARMACY | IDENTIFICATION | PROGRESSION
Journal Article
Biochemistry, ISSN 0006-2960, 06/2007, Volume 46, Issue 22, pp. 6607 - 6616
Journal Article