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cynaropicrin (86) 86
index medicus (41) 41
sesquiterpene lactones (27) 27
sesquiterpene lactone (22) 22
pharmacology & pharmacy (19) 19
chemistry, medicinal (18) 18
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lactones - pharmacology (16) 16
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cynara-scolymus l (9) 9
guaianolides (9) 9
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asteraceae (8) 8
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in-vitro (8) 8
apoptosis (7) 7
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cynara cardunculus (5) 5
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-germacrene (3) 3
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anti-inflammatory effect (3) 3
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Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 12/2015, Volume 25, Issue 23, pp. 5504 - 5507
Cynaropicrin is a guaianolide sesquiterpene lactone, which has potent in vitro and in vivo inhibitory activity against , the protozoan parasite that causes... 
Deuterium | Cynaropicrin | Guaianolide | Pharmacokinetic study | Trypanosoma brucei
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 06/2019, Volume 29, Issue 12, pp. 1518 - 1521
Cynaropicrin is a guaianolide sesquiterpene lactone with a 5-7-5 tricyclic skeleton, four exo-olefins, and two hydroxyl groups. This natural product has... 
Cynaropicrin | NF-κB | Derivatization | SAR | CHEMISTRY, MEDICINAL | NF-kappa B | CHEMISTRY, ORGANIC | SESQUITERPENE LACTONES
Journal Article
Tetrahedron Letters, ISSN 0040-4039, 12/2016, Volume 57, Issue 52, pp. 5899 - 5901
Cnicin is a germacranolide sesquiterpene lactone that possesses potent inhibitory activity against the protozoan parasite , which causes human African... 
Isolation | Sesquiterpene lactone | Cnicin | Esterification | l-Ascorbic acid | L-Ascorbic acid | PRODUCTS | CYNAROPICRIN | CHEMISTRY, ORGANIC | DERIVATIVES | EFFICIENT | SESQUITERPENE LACTONES
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 06/2019, Volume 67, Issue 23, pp. 6487 - 6496
The excessive and inappropriate application of herbicides has caused environmental pollution. The use of allelochemicals as bioherbicides could provide a... 
allelopathy | weed control | sesquiterpene lactones | Cynara cardunculus | cynaropicrin | ALLELOCHEMICALS | WEED | FOOD SCIENCE & TECHNOLOGY | LEAVES | PHYTOTOXICITY | ARTICHOKE | CULTIVARS | GROWTH | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED | Index Medicus
Journal Article
Chemistry of Natural Compounds, ISSN 0009-3130, 11/2018, Volume 54, Issue 6, pp. 1177 - 1179
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 12074 - 13
Bitter taste is an innately aversive taste modality that is considered to protect animals from consuming toxic compounds. Yet, bitterness is not always noxious... 
ACTIVATE | GROSHEIMIN | PEPTIDES | DATABASE | CYNAROPICRIN | MULTIDISCIPLINARY SCIENCES | RECEPTOR TAS2R14 | CLASSIFICATION | DERIVATIVES | DISCOVERY | RESOURCE | Learning algorithms | Taste | Bitterness | Natural products | Bitter taste
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 05/2019, Volume 135, pp. 216 - 226
Journal Article
Trends in Food Science & Technology, ISSN 0924-2244, 04/2019, Volume 86, pp. 381 - 391
Journal Article
Plant Science, ISSN 0168-9452, 2014, Volume 223, pp. 59 - 68
Cynara cardunculus (Asteraceae) is a cross pollinated perennial crop which includes the two cultivatedtaxa globe artichoke and cultivated cardoon. The leaves... 
chicory | globe artichoke | scolymus l | biological-activities | (+)-germacrene | cynaropicrin | synthase | yeast expression | costunolide | artichoke leaf extract
Journal Article
by Sato, T and Hara, S and Sato, M and Ogawa, K and Adams, M and Usuki, T
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 12/2015, Volume 25, Issue 23, pp. 5504 - 5507
Journal Article
Industrial Crops & Products, ISSN 0926-6690, 03/2019, Volume 129, pp. 206 - 211
The growth inhibition of bacterial species through bioactive natural compounds is an already consolidated purpose in the scientific community, with the dual... 
Cynaropicrin | Antimicrobial activity | Flavonoids | Cardoon | Caffeoylquinic acids | POMEGRANATE PEEL EXTRACT | WILD | AGRONOMY | QUALITY | ESSENTIAL OILS | PHENOLIC-COMPOUNDS | SESQUITERPENE LACTONES | AGRICULTURAL ENGINEERING | ANTIOXIDANT | CHEMICAL-COMPOSITION | SCOLYMUS L
Journal Article
Toxicology Letters, ISSN 0378-4274, 04/2015, Volume 234, Issue 2, pp. 74 - 80
Due to its antioxidant and anti-inflammatory activities, ( ) has been used as folk medicine to treat various diseases. Cynaropicrin (Cyn), a sesquiterpene... 
Nqo1 | Cynaropicrin | AhR | Antioxidant | Nrf2 | Ultraviolet B | ACTIVATION | CANCER | HUMAN KERATINOCYTES | DAMAGE | CYNARA-SCOLYMUS L | SIGNALING PATHWAY | TOXICOLOGY | NF-KAPPA-B | EXPRESSION | SKIN INFLAMMATION | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Keratinocytes - radiation effects | Humans | NAD(P)H Dehydrogenase (Quinone) - genetics | RNA, Messenger - metabolism | Lactones - pharmacology | Dose-Response Relationship, Drug | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | RNA Interference | Inflammation Mediators - metabolism | Receptors, Aryl Hydrocarbon - metabolism | NF-E2-Related Factor 2 - genetics | Oxidative Stress - radiation effects | Active Transport, Cell Nucleus | Basic Helix-Loop-Helix Transcription Factors - drug effects | Interleukin-6 - metabolism | Keratinocytes - enzymology | Cytoprotection | Basic Helix-Loop-Helix Transcription Factors - genetics | Cells, Cultured | Receptors, Aryl Hydrocarbon - genetics | Receptors, Aryl Hydrocarbon - drug effects | Antioxidants - pharmacology | Ultraviolet Rays - adverse effects | Keratinocytes - drug effects | Signal Transduction - drug effects | NF-E2-Related Factor 2 - metabolism | NAD(P)H Dehydrogenase (Quinone) - metabolism | Oxidative Stress - drug effects | Sesquiterpenes - pharmacology | Antioxidants | Skin | Index Medicus | Pathways | Cytokines | Artichokes | Biocompatibility | Activation | Ultraviolet | Diseases
Journal Article