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European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 04/2019, Volume 131, pp. 177 - 194
Journal Article
Toxicology Letters, ISSN 0378-4274, 09/2016, Volume 258, pp. 267 - 275
Cytochrome P4501A1 is involved in the metabolism of carcinogenic polycyclic aromatic hydrocarbons; therefore, its inhibition interferes with the carcinogenesis... 
Naringenin | CYP1A1 inhibitor | Dihydroxybergamottin | Molecular modeling | MOLECULAR-DYNAMICS | IN-VITRO INHIBITION | SIMVASTATIN METABOLISM | PARTICLE MESH EWALD | CYTOCHROMES P450 1A1 | O-DEETHYLATION | SUBSTRATE-BINDING | CARCINOGEN METABOLISM | TOXICOLOGY | HUMAN-LIVER-MICROSOMES | Cytochrome P-450 CYP1A1 - genetics | Rats, Wistar | Humans | Molecular Conformation | Cytochrome P-450 CYP1A1 - antagonists & inhibitors | Cytochrome P-450 Enzyme Inhibitors - metabolism | Anticarcinogenic Agents - metabolism | Flavanones - chemistry | Microsomes, Liver - drug effects | Cytochrome P-450 Enzyme Inhibitors - chemistry | Microsomes, Liver - enzymology | Anticarcinogenic Agents - pharmacology | Furocoumarins - chemistry | Binding, Competitive | Recombinant Proteins - metabolism | Catalytic Domain | Furocoumarins - metabolism | Furocoumarins - pharmacology | Citrus paradisi - chemistry | Flavanones - pharmacology | Food-Drug Interactions | Models, Molecular | Rats | Recombinant Proteins - chemistry | Cytochrome P-450 CYP1A1 - metabolism | Cytochrome P-450 CYP1A1 - chemistry | Molecular Dynamics Simulation | Cytochrome P-450 Enzyme Inhibitors - pharmacology | Animals | Anticarcinogenic Agents - chemistry | Flavanones - metabolism | Fruit and Vegetable Juices - analysis | Ligands | Molecular Docking Simulation | Cytochrome P-450 | Fruit juices | Physiological aspects | Polycyclic aromatic hydrocarbons | Index Medicus | Enzymes | Carcinogens | Inhibitors | Computation | Grapefruit | Mathematical models | Juices | Inhibition
Journal Article
Biochemical pharmacology, ISSN 0006-2952, 12/2018, Volume 158, pp. 174 - 184
Dolutegravir (DTG), a potent integrase inhibitor, is part of a recommended initial regimen for the treatment of human immunodeficiency virus (HIV). Prior... 
CYP1A1 | CYP1B1 | Dolutegravir HIV | Metabolism
Journal Article
Chemical Research in Toxicology, ISSN 0893-228X, 09/2012, Volume 25, Issue 9, pp. 1878 - 1884
Journal Article
Journal Article
Journal Article