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FEBS Journal, ISSN 1742-464X, 03/2014, Volume 281, Issue 5, pp. 1379 - 1392
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 06/2018, Volume 58, Issue 6, pp. 750 - 761
Conventional opioids bind to μ‐opioid receptors and activate 2 downstream signaling pathways: G‐protein coupling, linked to analgesia, and β‐arrestin... 
Pain perception | Narcotics | Opioid receptors | Body weight | Cytochrome P450 | Arrestin | Pharmacology | Recruitment | Proteins | Analgesia | Receptors | Pain | Ligands | Mathematical models | Coupling | Pharmacokinetics | CYP2D6 protein | Index Medicus
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 06/2018, Volume 58, Issue 6, pp. 762 - 770
Oliceridine is a novel G protein–biased ligand at the μ‐opioid receptor that differentially activates G protein coupling while mitigating β‐arrestin... 
Dosing | Pain perception | Computer simulation | Narcotics | Opioid receptors | Cytochrome P450 | Morphine | Arrestin | Pharmacology | Patients | Proteins | Analgesia | Pain | Metabolites | Simulation | Ligands | Mathematical models | Genotypes | CYP2D6 protein | Index Medicus
Journal Article
Journal Article
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 10/2017, Volume 121, Issue 4, pp. 334 - 341
Of late, many studies are attempting to find new molecules with anticancer properties, especially those with the capability to inhibit cell growth. The aim of... 
CANCER-CELLS | APOPTOSIS | COMET ASSAY | C-MYC | PHARMACOLOGY & PHARMACY | ANTICANCER DRUGS | KINASE INHIBITORS | TOXICITY | TOXICOLOGY | MELANOMA-CELLS | INDUCTION | CYCLE | Activation, Metabolic | Sesquiterpenes - metabolism | Apoptosis - drug effects | Humans | Dose-Response Relationship, Drug | Carcinoma, Hepatocellular - drug therapy | Time Factors | Carcinoma, Hepatocellular - genetics | Apoptosis Regulatory Proteins - genetics | Cell Cycle Proteins - genetics | Liver Neoplasms - pathology | Antineoplastic Agents, Phytogenic - metabolism | Liver Neoplasms - enzymology | Endoplasmic Reticulum Stress - drug effects | Liver Neoplasms - genetics | Oxidation-Reduction | Cell Cycle Proteins - metabolism | Liver Neoplasms - drug therapy | Carcinoma, Hepatocellular - enzymology | Cytochrome P-450 CYP1A2 - metabolism | Apoptosis Regulatory Proteins - metabolism | Hep G2 Cells | Carcinoma, Hepatocellular - pathology | Cytochrome P-450 CYP2C19 - metabolism | Cell Proliferation - drug effects | Sesquiterpenes - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | G1 Phase Cell Cycle Checkpoints - drug effects | Cell death | Cytochrome P-450 | Physiological aspects | Biochemistry | Stress (Physiology) | Hepatoma | Tumor proteins | Xenobiotics | Gene expression | Cell proliferation | Bax protein | Genotoxicity | Cytotoxicity | Hepatocellular carcinoma | Myc protein | Kinases | Phase transitions | Liver cancer | Mitochondria | Cell growth | Nerolidol | Cell cycle | Oxidation | Membrane potential | CYP2D6 protein | G1 phase | Enzymes | Cell survival | Cytochrome P450 | Caspase | CYP1A2 protein | Metabolism | Survival | Cyclins | Cyclin-dependent kinase 2 | Endoplasmic reticulum | Phase transition | Apoptosis | Index Medicus
Journal Article
Biological and Pharmaceutical Bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 9, pp. 1344 - 1351
Journal Article