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Chinese medical journal, ISSN 0366-6999, 11/2018, Volume 131, Issue 22, pp. 2693 - 2698
Journal Article
British journal of clinical pharmacology, ISSN 0306-5251, 12/2015, Volume 80, Issue 6, pp. 1438 - 1446
Journal Article
Drug Metabolism Reviews, ISSN 0360-2532, 2004, Volume 36, Issue 1, pp. 57 - 104
P-glycoprotein (Pgp) is a 170 kDa phosphorylated glycoprotein encoded by human MDR1 gene. It is responsible for the systemic disposition of numerous... 
P-glycoprotein | Grapefruit juice | Drug interactions | Herb | St. John's wort | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Animals | Phytotherapy | Plants, Medicinal - metabolism | Herb-Drug Interactions | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Index Medicus
Journal Article
Pharmacognosy journal, 11/2018, Volume 10, Issue 6, pp. 1093 - 1095
Journal Article
Drug metabolism letters, ISSN 1872-3128, 06/2016, Volume 10, Issue 2, pp. 111 - 123
Journal Article
World journal of gastroenterology : WJG, ISSN 1007-9327, 12/2013, Volume 19, Issue 48, pp. 9156 - 9173
Journal Article
Current drug metabolism, ISSN 1389-2002, 11/2010, Volume 11, Issue 9, pp. 716 - 729
Bioavailability of orally administered drugs can be influenced by a number of factors including release from the formulation, dissolution, stability in the... 
BDDCS | P-glycoprotein | ADAM | BCS | CYP3A4 | Transporter | Fraction absorbed | Gut metabolism | Simcyp | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology
Journal Article
European journal of pharmaceutical sciences, ISSN 0928-0987, 03/2018, Volume 114, pp. 55 - 63
The tyrosine kinase inhibitors sorafenib and imatinib are important in the treatment of a range of cancers but adverse effects in some patients necessitate... 
Imatinib biotransformation | CYP2C8 | Sorafenib biotransformation | Hepatic cirrhosis | CYP3A4 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Index Medicus
Journal Article
Current drug metabolism, ISSN 1389-2002, 05/2008, Volume 9, Issue 4, pp. 310 - 322
Journal Article
Pharmacogenetics and genomics, ISSN 1744-6872, 01/2016, Volume 26, Issue 1, pp. 40 - 43
Cytochrome P450 3A4 (CYP3A4) metabolizes 30–50% of clinically used drugs. Large interperson variability in CYP3A4 activity affects response to CYP3A4 substrate... 
polymorphism | alternative splicing | CYP3A4 | gene expression | 22 allele | Cell Line | RNA Splicing | Cytochrome P-450 CYP3A - genetics | Introns | Humans | Liver - cytology | Polymorphism, Single Nucleotide | Organ Specificity | RNA, Messenger - metabolism | Hep G2 Cells | Intestines - cytology | Index Medicus | CYP3A422 allele
Journal Article