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10/2008
Background: The dynamic liver function test based on the hepatic conversion of lidocaine to monoethylglycinexylidide (MEGX) provides a direct measure of the... 
monoethylglycinexylidide | metabolism | CYP3A4 | lidocaine
Web Resource
Chinese Medical Journal, ISSN 0366-6999, 11/2018, Volume 131, Issue 22, pp. 2693 - 2698
Journal Article
International Journal of Clinical Pharmacology and Therapeutics, ISSN 0946-1965, 08/2015, Volume 53, Issue 8, pp. 647 - 657
Journal Article
Clinica Chimica Acta, ISSN 0009-8981, 04/2011, Volume 412, Issue 9-10, pp. 755 - 760
Purpose: This study aimed to investigate the impact of CYP3A4*1G genetic polymorphism on metabolism of fentanyl in Chinese patients undergoing lower abdominal... 
Fentanyl | CYP3A4 | Gene polymorphism | HPLC
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 12/2015, Volume 80, Issue 6, pp. 1438 - 1446
Journal Article
Drug Metabolism and Pharmacokinetics, ISSN 1347-4367, 07/2019
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Yakugaku Zasshi, ISSN 0031-6903, 2017, Volume 137, Issue 10, pp. 1209 - 1214
Journal Article
Frontiers in Genetics, ISSN 1664-8021, 2013, Volume 4, pp. 12 - 12
CYP3A4 is the most important drug metabolizing enzyme in adult humans because of its prominent expression in liver and gut and because of its broad substrate... 
Drug metabolism | Pharmacogenetics | Heritability | CYP3A4 | Cytochrome P450 | Pharmacogenomics
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 07/2014, Volume 24, Issue 13, pp. 2877 - 2880
Based on their structural similarity to previously described compound AMG 009, indole-phenyl acetic acids were proposed to be potent dual inhibitors of... 
CRTH2 | Phenylacetic acid | CYP3A4 | Indole
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 06/2004, Volume 60, Issue 4, pp. 231 - 236
Journal Article
MEDICINA CLINICA, ISSN 0025-7753, 02/2018, Volume 150, Issue 4, pp. 163 - 164
Journal Article
Food Chemistry, ISSN 0308-8146, 2013, Volume 141, Issue 2, pp. 920 - 926
Ganoderma resinaceum Boud. (Polyporeseae) has long been used for antioxidant, immunoregulation and liver protection. From the fruiting bodies of G. resinaceum,... 
Ganoderma triterpenoids | Hepatoprotective activities | Ganoderma resinaceum | HepG2 cells | CYP3A4
Journal Article
Xenobiotica, ISSN 0049-8254, 10/2019, Volume 49, Issue 10, pp. 1164 - 1172
ZYTP1 is a novel Poly (ADP-ribose) polymerase protein inhibitor being developed for cancer indications. The focus of the work was to determine if ZYTP1 had a... 
Time dependent CYP3A4/5 inhibition | drug metabolism | ZYTP1 | POLY(ADP-RIBOSE) | DRUG-INTERACTIONS | Time dependent CYP3A4 | 5 inhibition | COCKTAIL | PHARMACOKINETICS | ENZYMES | PHARMACOLOGY & PHARMACY | JUICE | TOXICOLOGY | PROBE
Journal Article
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