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1. Full Text The effects of H 2 s on the activities of CYP2B6, CYP2D6, CYP3A4, CYP2C19 and CYP2C9 in vivo in rat
by Wang, Xianqin and Han, Anyue and Wen, Congcong and Chen, Mengchun and Chen, Xinxin and Yang, Xuezhi and Ma, Jianshe and Lin, Guanyang
International journal of molecular sciences, ISSN 1661-6596, 12/2013, Volume 14, Issue 12, pp. 24055 - 24063
LC-MS | CYP450 | Cocktail
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2. Full Text Prevention of aflatoxin B1 hepatoxicity by dietary selenium is associated with inhibition of cytochrome P450 isozymes and up-regulation of 6 selenoprotein genes in chick liver
by Sun, Lv-Hui and Zhang, Ni-Ya and Zhu, Ming-Kun and Zhao, Ling and Zhou, Ji-Chang and Qi, De-Sheng
The Journal of nutrition, ISSN 0022-3166, 04/2016, Volume 146, Issue 4, pp. 655 - 661
Chicks | Selenium | Selenoproteins | Aflatoxin B | CYP450 | Index Medicus
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3. Full Text Using chemical bond-based method to predict site of metabolism for five biotransformations mediated by CYP 3A4, 2D6, and 2C9
by Fu, XuYan and He, ShuaiBing and Du, Li and Lv, ZhaoLei and Zhang, Yi and Zhang, Qian and Wang, Yun
Biochemical pharmacology, ISSN 0006-2952, 06/2018, Volume 152, pp. 302 - 314
CYP450 2D6 | SOMP | CYP450 3A4 | Chemical bond-based method | CYP450 2C9 | Metabolites prediction | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Medicinal plants | Metabolites | Hydroxylation | Analysis | Medicine, Botanic | Bonds | Cytochrome P-450 | Physiological aspects | Medicine, Chinese | Medicine, Herbal | Chemical properties | Methods | Index Medicus
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4. Full Text No Effect of SLCO1B1 and CYP3A4/5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Ticagrelor in Healthy Chinese Male Subjects
by Mupeng Lia and b and Yaodong Huc and Huilan Lid and Zhipeng Wena and Xiaolei Hua and Daoyu Zhanga and Yanjiao Zhanga and Jian Xiaod and Jie Tanga and Xiaoping Chena and Central South University ; Hunan Key Laboratory of Pharmacogenetics and Heping Hospital Affiliated to Changzhi Medical College and Central South University and bInstitute of Clinical Pharmacology and dDepartment of Pharmacy and aDepartment of Clinical Pharmacology and cDepartment of Cardiology and Xiangya Hospital
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2017, Volume 40, Issue 1, pp. 88 - 96
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5. Full Text Analysis of CYP450 gene allelic variants can predict ifosfamide toxicity in Mexican paediatric patients
by Torres Espíndola, Luz María and Rojo-Serrato, Daniela and Álvaro-Heredia, Antonio and Castillejos López, Manuel de Jesús and de Uña-Flores, Armando and Pérez-García, Martin and Zapata-Tarres, Marta and Cárdenas-Cardos, Rocio and Granados, Julio and Chávez-Pacheco, Juan Luis and Salinas-Lara, Citlaltepetl and de Arellano, Israel Torres-Ramirez and Aquino-Gálvez, Arnoldo
Biomarkers, ISSN 1354-750X, 05/2020, Volume 25, Issue 4, pp. 331 - 340
toxicity | ifosfamide | CYP450 | prognosis | Polymorphism | Index Medicus
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6. Letter to the editor
by Eikelenboom-Schieveld, Selma J.M and Fogleman, James C
Pharmacogenomics, ISSN 1462-2416, 2018, Volume 19, Issue 14, pp. 1095 - 1096
SSRIs | CYP450 genotype | phenoconversion | aggressive behavior
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7. Full Text Exploration of xenobiotic metabolism within cell lines used for Tox21 chemical screening
by Qu, Wei and Crizer, David M and DeVito, Michael J and Waidyanatha, Suramya and Xia, Menghang and Houck, Keith and Ferguson, Stephen S
Toxicology in vitro, ISSN 0887-2333, 06/2021, Volume 73, pp. 105109 - 105109
CYP450 | Xenobiotic metabolism | Metabolic clearance | Primary human hepatocytes | Metabolic competence | Bisphenol | Tox21 | Index Medicus
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8. Full Text Evaluation of an in-capillary approach for performing quantitative cytochrome P450 activity studies
by Curcio, R and Nicoli, R and Rudaz, S and Veuthey, J.-L
Analytical and bioanalytical chemistry, ISSN 1618-2642, 11/2010, Volume 398, Issue 5, pp. 2163 - 2171
Biochemistry, general | Chemistry | Analytical Chemistry | Food Science | Measurement Science and Instrumentation | CYP450 | CYP450 kinetics | Drug metabolism | Laboratory Medicine | Environmental Monitoring/Analysis | Drug–drug interactions | In-capillary enzymatic assays | Drug-drug interactions | Biochemistry & Molecular Biology | Physical Sciences | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Analytical chemistry | Chromatographic methods and physical methods associated with chromatography | Other chromatographic methods | Exact sciences and technology | Spectrometric and optical methods | Cytochrome P-450 Enzyme System - analysis | Humans | Mass Spectrometry | Cytochrome P-450 Enzyme System - metabolism | Biological Assay - methods | Kinetics | Chromatography, Liquid - methods | Isoenzymes | Analysis | Cytochrome P-450 | Physiological aspects | Liquid chromatography | Mass spectrometry | Methods | Drugs | Capillarity | Reaction kinetics | Capillary pressure | In vitro testing | Nanostructure | Assaying | Metabolism | Cytochromes P450 | Index Medicus
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9. Full Text Establishment of ornithine transcarbamylase deficiency-derived primary human hepatocyte with hepatic functions
by Su, Shan and Di Poto, Cristina and Kroemer, Alexander H and Cui, Wanxing and Roy, Rabindra and Liu, Xuefeng and Ressom, Habtom W
Experimental cell research, ISSN 0014-4827, 11/2019, Volume 384, Issue 1, pp. 111621 - 111621
Ornithine transcarbamylase deficiency (OTCD) | Long-term culture | CYP450 activity | Primary human hepatocyte (PHH) | Index Medicus | primary human hepatocyte (PHH) | long-term culture | ornithine transcarbamylase deficiency (OTCD)
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10. Full Text Tethered spheroids as an invitro hepatocyte model for drug safety screening
by Xia, Lei and Sakban, Rashidah Binte and Qu, Yinghua and Hong, Xin and Zhang, Wenxia and Nugraha, Bramasta and Tong, Wen Hao and Ananthanarayanan, Abhishek and Zheng, Baixue and Chau, Ian Yin-Yan and Jia, Ruirui and McMillian, Michael and Silva, Jose and Dallas, Shannon and Yu, Hanry
Biomaterials, ISSN 0142-9612, 03/2012, Volume 33, Issue 7, pp. 2165 - 2176
CYP450 enzymes | 3D hepatocyte model | Drug safety testing | Galactose | Xenobiotics | RGD
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11. Mechanism-based inhibition of CYP450: An indicator of drug-induced hepatotoxicity
by Feng, Shan and He, Xin
Current drug metabolism, ISSN 1389-2002, 11/2013, Volume 14, Issue 9, pp. 921 - 945
Reactive metabolites | Immune response | GSH depletion | CYP450 | Mechanism-based inhibition | CYP450 RNA or protein induction | Hepatotoxicity | Pharmacology & Pharmacy | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology
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12. Full Text The pharmacology of statins
by Sirtori, Cesare R
Pharmacological research, ISSN 1043-6618, 10/2014, Volume 88, pp. 3 - 11
Hypercholesterolemia | HMG-CoA reductase inhibitors | CYP450 | LDL receptors | Mycetes | OATP | Statins | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Diabetes Mellitus - epidemiology | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Chemical and Drug Induced Liver Injury | Muscular Diseases - chemically induced | Physiological aspects | Pharmacology | Blood cholesterol | Low density lipoproteins | Cytochrome P-450 | Index Medicus
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13. CYP2C9∗61, a rare missense variant identified in a Puerto Rican patient with low warfarin dose requirements
by Claudio-Campos, Karla I and González-Santiago, Pablo and Renta, Jessica Y and Rodríguez, Jovaniel and Carrasquillo, Kelvin and Gaedigk, Andrea and Roche, Abiel and Ducongé, Jorge
Pharmacogenomics, ISSN 1462-2416, 01/2019, Volume 20, Issue 1, pp. 3 - 8
CYP2C9 | Pharmacogenetics (PGx) | Warfarin | Next-generation sequencing | CYP450 | Anticoagulation | Haplotype | Hispanics
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14. Full Text Aspergillus flavus (Link) toxins reduces the fitness of dengue vector Aedes aegypti (Linn.) and their non-target toxicity against aquatic predator
by Vasantha-Srinivasan, Prabhakaran and Karthi, Sengodan and Chellappandian, Muthiah and Ponsankar, Athirstam and Thanigaivel, Annamalai and Senthil-Nathan, Sengottayan and Chandramohan, Devarajan and Ganesan, Raja
Microbial pathogenesis, ISSN 0882-4010, 03/2019, Volume 128, pp. 281 - 287
GST | CYP450 | Midgut | Biosafety | Dengue | Mycotoxins | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Mosquitoes | Metabolites | Health aspects | Mortality | Cytochrome P-450 | Index Medicus
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