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Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2017, Volume 377, Issue 21, pp. 2013 - 2023
Patients with homozygous Phe508del cystic fibrosis were assigned to receive combination tezacaftor–ivacaftor or placebo for 24 weeks. The combination resulted... 
G551D MUTATION | MEDICINE, GENERAL & INTERNAL | IN-VITRO | LUMACAFTOR | EFFICACY | SAFETY | AGED 6-11 YEARS | F508DEL-CFTR | PHASE-3 | CFTR POTENTIATOR | COMBINATION | Proteins | Clinical trials | Cystic fibrosis | Mutation | Drug therapy | Patients | Drug dosages | Quality of life | Pharmaceuticals | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2015, Volume 373, Issue 3, pp. 220 - 231
Journal Article
Chest, ISSN 0012-3692, 05/2017, Volume 151, Issue 5, pp. 982 - 992
Objectives We sought to describe the characteristics of adult patients with bronchiectasis enrolled in the US Bronchiectasis Research Registry (BRR). Methods... 
registry | airways | nontuberculous mycobacteria | Pseudomonas | bronchiectasis | LUNG-FUNCTION | PULMONARY-FUNCTION | NON-CF BRONCHIECTASIS | RESPIRATORY SYSTEM | CYSTIC FIBROSIS BRONCHIECTASIS | PSEUDOMONAS-AERUGINOSA | INFECTION | CRITICAL CARE MEDICINE | Spirometry | United States - epidemiology | Humans | Middle Aged | Hispanic Americans - statistics & numerical data | Male | Tomography, X-Ray Computed | Gastroesophageal Reflux - epidemiology | Sinusitis - epidemiology | Forced Expiratory Volume | Mycobacterium Infections, Nontuberculous - microbiology | Adult | Biomedical Research | Female | Registries | Insurance, Health | Staphylococcus aureus | Asthma - epidemiology | Nontuberculous Mycobacteria | Ethnic Groups - statistics & numerical data | Immunologic Deficiency Syndromes - epidemiology | Comorbidity | European Continental Ancestry Group - statistics & numerical data | Kartagener Syndrome - epidemiology | Bronchiectasis - microbiology | Mycobacterium Infections, Nontuberculous - epidemiology | Vital Capacity | African Americans - statistics & numerical data | Animals | Staphylococcal Infections - epidemiology | Pseudomonas Infections - epidemiology | Bronchiectasis - epidemiology | Smoking - epidemiology | Otitis - epidemiology | Aged | Rhinitis - epidemiology | Bronchiectasis - physiopathology | Antibiotics | Adults | Dosage and administration | Bronchiectasis | Diagnosis | Research | Health aspects | Index Medicus | Abridged Index Medicus | PEP, positive expiratory pressure | BRR, Bronchiectasis Research Registry | NCFB, non-cystic-fibrosis bronchiectasis | LUL, left upper lobe | CF, cystic fibrosis | AFB, acid-fast bacillus | NTM, nontuberculous mycobacteria | RUL, right upper lobe | GERD, gastroesophageal reflux | DCC, data coordinating center | RML, right middle lobe
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 131, Issue 4, pp. 1117 - 1129.e5
Background IL-17 is an important cytokine signature of the TH differentiation pathway TH 17. This T-cell subset is crucial in mediating autoimmune disease or... 
Allergy and Immunology | memory T-cell response | TH22 | Aspergillus species | lung transplant | cystic fibrosis | IL-17 | Pseudomonas species | chronic infectious disease | TH17 | IL-22 | IL-17 RECEPTOR | TGF-BETA | COLONY-STIMULATING FACTOR | MUCOSAL HOST-DEFENSE | IMMUNOLOGY | NEUTROPHIL RECRUITMENT | MATRIX METALLOPROTEINASES | OBSTRUCTIVE PULMONARY-DISEASE | ALLERGY | REGULATORY T-CELLS | KLEBSIELLA-PNEUMONIAE | TH17 CELLS | Lymph Nodes - pathology | Humans | Middle Aged | Antigens, Bacterial - immunology | Aspergillus - chemistry | Cystic Fibrosis - pathology | Interleukin-17 - immunology | Male | Case-Control Studies | Cystic Fibrosis - immunology | Interleukins - genetics | Th17 Cells - drug effects | Antigens, Fungal - pharmacology | Interleukins - immunology | Adult | Female | Lymph Nodes - drug effects | Th17 Cells - pathology | Gene Expression | Lung - pathology | Interleukin-17 - genetics | Antigens, Bacterial - pharmacology | Immunophenotyping | Antigens, Fungal - immunology | Lymph Nodes - immunology | Pseudomonas aeruginosa - chemistry | Lymphocyte Activation - drug effects | Cystic Fibrosis - genetics | Lung - drug effects | Th17 Cells - immunology | Immunologic Memory | Aged | Cell Proliferation - drug effects | Lung - immunology | Studies | Human subjects | Antigens | Transplants & implants | Disease | Lungs | Review boards | Cystic fibrosis | Chronic obstructive pulmonary disease | Fungal infections | Immune system | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 11/2011, Volume 365, Issue 18, pp. 1663 - 1672
Journal Article