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Archives of Biochemistry and Biophysics, ISSN 0003-9861, 03/2019, Volume 664, pp. 117 - 126
Extracellular cystine (CYC) uptake by antiporter is important for the cell viability. Especially in cancer cells, the upregulation of activity is observed,... 
CELLS | BIOPHYSICS | CYSTINE/GLUTAMATE ANTIPORTER | SYSTEM X(C)(-) | GLUTATHIONE | GLUTAMATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FORCE-FIELD | MECHANISMS | MOLECULAR-DYNAMICS SIMULATIONS | CANCER | EXPRESSION
Journal Article
Journal Article
Glia, ISSN 0894-1491, 08/2016, Volume 64, Issue 8, pp. 1381 - 1395
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0127785
The cystine-glutamate antiporter (system x(c)(-)) is a Na+-independent amino acid transporter that exchanges extracellular cystine for intracellular glutamate.... 
PRIMARY BRAIN-TUMORS | OXIDATIVE STRESS | TRANSPORT | INHIBITION | HUMAN-DIPLOID FIBROBLASTS | SYSTEM X(C)(-) | CYSTINE/GLUTAMATE ANTIPORTER | MULTIDISCIPLINARY SCIENCES | GROWTH | MALIGNANT GLIOMAS | FACTOR-KAPPA-B | Glycine - analogs & derivatives | Humans | RNA, Messenger - genetics | Brain Neoplasms - genetics | Amino Acid Transport System y+ - genetics | Sulfasalazine - pharmacology | RNA, Messenger - metabolism | Brain Neoplasms - metabolism | Cystine - pharmacology | Glioma - metabolism | Glioma - genetics | Amino Acid Transport System y+ - metabolism | Glycine - pharmacology | Time Factors | Databases, Chemical | Models, Biological | Cystine - metabolism | Benzoates - pharmacology | Cell Line, Tumor | Inhibitory Concentration 50 | Glutamic Acid - metabolism | Gene Expression Regulation, Neoplastic - drug effects | High-Throughput Screening Assays - methods | Brain | Neurosciences | Pathogenesis | Brain cancer | Brain tumors | High-throughput screening | Amino acids | Assaying | Cystine | PharmacoPhores | Proteins | Neurotoxicity | Cell growth | Metabolites | Rodents | Glioma cells | Cell cycle | Fibroblasts | Carbon 14 | Glutathione | Neurochemistry | Neurodegenerative diseases | Incubation | Pharmacology | Inflammation | Metabolism | Medical screening | Molecular chains | Microglia | Medicine | Cell death | Excitotoxicity | Intracellular | Alzheimers disease | Transporter | Cancer | Apoptosis | Logistics
Journal Article