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Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 11/2017, Volume 359, Issue 22, pp. 3983 - 3989
N‐Protected β‐ and γ‐amino epoxides are useful chiral synthons. We report here that the enzyme cytochrome P450 3A4 can catalyze the formation of such compounds... 
chemical auxiliaries | epoxidation | cytochrome P450 3A4 | biocatalysis | theobromine | COMPLEX | ENANTIOSELECTIVE SYNTHESIS | LYSINE | CHEMISTRY, ORGANIC | ENZYMES | IN-VIVO | OLEFINS | CHEMISTRY, APPLIED | DERIVATIVES | C-H AMINATION
Journal Article
Journal Article
Journal Article
Pediatric Pulmonology, ISSN 8755-6863, 05/2018, Volume 53, Issue 5, pp. E6 - E8
The CFTR potentiator ivacaftor is responsible for significant clinical improvements among a subset of patients with cystic fibrosis. Because it is a substrate... 
cytochrome P450 | ivacaftor | drug‐drug interaction | rifampin | CFTR | drug-drug interaction | RESPIRATORY SYSTEM | PEDIATRICS | Complications and side effects | Rifampin | Drug interactions
Journal Article
Transplant Infectious Disease, ISSN 1398-2273, 10/2017, Volume 19, Issue 5, pp. e12751 - n/a
Journal Article
Bioconjugate Chemistry, ISSN 1043-1802, 04/2017, Volume 28, Issue 4, p. 885
Human cytochrome P450 3A4 (CYP3A4) is responsible for the metabolism of the majority of drugs. As such, it is implicated in many adverse drug-drug and... 
Cytochrome | Drugs | Cytochrome P450 | Metabolism | Coumarin | Substrates | Mutants | Molecules | Testosterone | Allosteric properties | Ligands | Oxidation | Mutation | Progesterone | Cooperativity | Kinetics | Enzyme kinetics | Pharmaceutical industry | Food
Journal Article