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1. Full Text Dynamic expression profiling of type I and type III interferon‐stimulated hepatocytes reveals a stable hierarchy of gene expression
by Bolen, Christopher R and Ding, Siyuan and Robek, Michael D and Kleinstein, Steven H
Hepatology (Baltimore, Md.), ISSN 0270-9139, 04/2014, Volume 59, Issue 4, pp. 1262 - 1272
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Phosphorylation | Humans | Hepatocytes - pathology | Gene Expression Profiling | Hepatocytes - metabolism | STAT1 Transcription Factor - metabolism | Time Factors | Feedback | Interferon Type I - pharmacology | Cell Line, Tumor | Gene Expression Regulation, Neoplastic - drug effects | Interleukins - pharmacology | Hepatocytes - drug effects | Medical research | Cytokines | Gene expression | Hepatology | Index Medicus | cytokine signaling | innate immunity | interferon | liver
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2. Full Text Plasticity of Foxp3+ T Cells Reflects Promiscuous Foxp3 Expression in Conventional T Cells but Not Reprogramming of Regulatory T Cells
by Miyao, Takahisa and Floess, Stefan and Setoguchi, Ruka and Luche, Hervé and Fehling, Hans Joerg and Waldmann, Herman and Huehn, Jochen and Hori, Shohei
Immunity (Cambridge, Mass.), ISSN 1074-7613, 02/2012, Volume 36, Issue 2, pp. 262 - 275
Life Sciences & Biomedicine | Immunology | Science & Technology | T-Lymphocyte Subsets - immunology | Inflammation - pathology | T-Lymphocytes, Regulatory - metabolism | T-Lymphocyte Subsets - cytology | Epigenesis, Genetic | Humans | CD2 Antigens - genetics | Lymphopenia - pathology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | DNA Methylation | Inflammation - metabolism | Forkhead Transcription Factors - metabolism | Lymphopenia - metabolism | T-Lymphocytes, Regulatory - cytology | CD2 Antigens - metabolism | Cell Differentiation | Cell Lineage - genetics | Gene Expression | Lymphocyte Activation | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Mice, Transgenic | Inflammation - immunology | Forkhead Transcription Factors - genetics | Mice, Knockout | Animals | Interleukin-2 Receptor alpha Subunit - metabolism | T-Lymphocyte Subsets - metabolism | Immunologic Memory | Lymphopenia - immunology | Mice | In Vitro Techniques | Cell Lineage - immunology | Transcription factors | Cytokines | Science | Cell division | Homeostasis | Artificial chromosomes | Proteins | Genotype & phenotype | Lymphocytes | Rodents | DNA methylation | Software | Deoxyribonucleic acid--DNA | Index Medicus
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3. Full Text Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon-β treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression
by Krakauer, M and Sorensen, P and Khademi, M and Olsson, T and Sellebjerg, F
Multiple sclerosis, ISSN 1352-4585, 06/2008, Volume 14, Issue 5, pp. 622 - 630
Multiple sclerosis | Cytokines | Interleukin-10 | Immunotherapy | Interferon-β treatment | Interleukin-23 | Autoimmune diseases | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Neurology | Biological and medical sciences | Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis | Medical sciences | Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases | Biomarkers - metabolism | Th1 Cells - drug effects | Th1 Cells - physiology | Multiple Sclerosis, Relapsing-Remitting - immunology | Th2 Cells - physiology | Gene Expression - drug effects | Multiple Sclerosis, Relapsing-Remitting - drug therapy | Humans | Multiple Sclerosis, Relapsing-Remitting - physiopathology | Transcription Factors - genetics | RNA, Messenger - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Th2 Cells - drug effects | Interleukin-23 - immunology | Interferon-beta - therapeutic use | Interleukin-23 - genetics | Interleukin-10 - genetics | Gene Expression - immunology | Interleukin-10 - immunology | Immunologic Factors - therapeutic use | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Cytometry by Time-of-Flight Shows Combinatorial Cytokine Expression and Virus-Specific Cell Niches within a Continuum of CD8 + T Cell Phenotypes
by Newell, Evan W and Sigal, Natalia and Bendall, Sean C and Nolan, Garry P and Davis, Mark M
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2012, Volume 36, Issue 1, pp. 142 - 152
Life Sciences & Biomedicine | Immunology | Science & Technology | Phenotype | Flow Cytometry | Cytokines - metabolism | Antigens, Viral, Tumor - immunology | CD8-Positive T-Lymphocytes - virology | Humans | Mass Spectrometry | CD8-Positive T-Lymphocytes - immunology | Principal Component Analysis | Antigens | Flow cytometry | Peptides | Cytokines | Cytotoxicity | Principal components analysis | Software | Viral infections | Index Medicus
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5. Full Text Tim-3 regulates pro- and anti-inflammatory cytokine expression in human CD14+ monocytes
by Ying Zhang and Cheng J. Ma and Jia M. Wang and Xiao J. Ji and Xiao Y. Wu and Jonathan P. Moorman and Zhi Q. Yao
Journal of leukocyte biology, ISSN 0741-5400, 02/2012, Volume 91, Issue 2, pp. 189 - 196
IL‐12 | innate immune regulation | macrophages | PD‐1 | IL-12 | Macrophages | PD-1 | Innate immune regulation | Immunology | Life Sciences & Biomedicine | Hematology | Science & Technology | Cell Biology | Up-Regulation | Interleukin-12 - genetics | Humans | Tumor Necrosis Factor-alpha - genetics | Monocytes - metabolism | Lipopolysaccharide Receptors - analysis | Membrane Proteins - physiology | Toll-Like Receptors - drug effects | Programmed Cell Death 1 Receptor - biosynthesis | Toll-Like Receptors - physiology | Cytokines - genetics | Interleukin-12 - biosynthesis | Down-Regulation | RNA, Small Interfering - pharmacology | Gene Expression Regulation | Immunity, Innate | Hepatitis A Virus Cellular Receptor 2 | Antibodies - pharmacology | Macrophages - metabolism | Membrane Proteins - antagonists & inhibitors | Interleukin-10 - genetics | Interleukin-10 - biosynthesis | Programmed Cell Death 1 Receptor - genetics | Tumor Necrosis Factor-alpha - biosynthesis | Cytokines - biosynthesis | Index Medicus | Spotlight on Leading Edge Research
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6. Full Text CD39 expression defines cell exhaustion in tumor-infiltrating CD8+ T cells
by Canale, Fernando P and Ramello, María C and Núñez, Nicolás and Furlan, Cintia L. Araujo and Bossio, Sabrina N and Serrán, Melisa Gorosito and Boari, Jimena Tosello and Del Castillo, Andrés and Ledesma, Marta and Sedlik, Christine and Piaggio, Eliane and Gruppi, Adriana and Rodríguez, Eva V. Acosta and Montes, Carolina L
Cancer research (Chicago, Ill.), ISSN 0008-5472, 01/2018, Volume 78, Issue 1, pp. 115 - 128
Life Sciences & Biomedicine | Oncology | Science & Technology | Cytokines - metabolism | Breast Neoplasms - immunology | Humans | Apyrase - metabolism | Lymphatic Metastasis - immunology | Male | Melanoma - pathology | Antigens, CD - metabolism | Mice, Knockout | Tumor Microenvironment - immunology | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - pathology | Melanoma - immunology | Adenosine Triphosphate - metabolism | Lymphatic Metastasis - pathology | CD8-Positive T-Lymphocytes - metabolism | Female | Lymphocytes, Tumor-Infiltrating - metabolism | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Lymphocytes, Tumor-Infiltrating - immunology | Nucleotidase | CD8 antigen | Recovery of function | Lymphocytes T | Cell surface | Interleukin 27 | Lymph nodes | Metastases | Interleukin 6 | T-cell receptor | Receptors | Interleukin 2 | Lymphocytes | Peripheral blood | Lymphatic system | Phenotypes | Melanoma | Organs | Breast cancer | T cell receptors | Immunosuppression | Tumor necrosis factor | Exhaustion | γ-Interferon | Biomarkers | ATP | Tumors | Cancer | Index Medicus
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7. Full Text Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone
by Di Gregorio, Gina B and Yao-Borengasser, Aiwei and Rasouli, Neda and Varma, Vijayalakshmi and Lu, Tong and Miles, Leslie M and Ranganathan, Gouri and Peterson, Charlotte A and McGehee, Robert E and Kern, Philip A
Diabetes (New York, N.Y.), ISSN 0012-1797, 08/2005, Volume 54, Issue 8, pp. 2305 - 2313
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Gene Expression | Cell Count | Humans | Middle Aged | Pioglitazone | Insulin Resistance | RNA, Messenger - analysis | Chemokine CCL2 - genetics | Macrophages | Reverse Transcriptase Polymerase Chain Reaction | Thiazolidinediones - administration & dosage | Antigens, CD - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Obesity - metabolism | Hypoglycemic Agents - administration & dosage | Muscles - chemistry | Adult | Adipose Tissue - chemistry | Metformin - administration & dosage | Cytokines - genetics | Cytokines - blood | Insulin resistance | Genetic aspects | Research | Diabetes | Cytokines | Index Medicus | Abridged Index Medicus
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8. Full Text Modulation of EZH2 expression in T cells improves efficacy of anti-CTLA-4 therapy
by Goswami, Sangeeta and Apostolou, Irina and Zhang, Jan and Skepner, Jill and Anandhan, Swetha and Zhang, Xuejun and Xiong, Liangwen and Trojer, Patrick and Aparicio, Ana and Subudhi, Sumit K and Allison, James P and Zhao, Hao and Sharma, Padmanee
The Journal of clinical investigation, ISSN 0021-9738, 08/2018, Volume 128, Issue 9, pp. 3813 - 3818
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Medical research | Transcription factors | Immunotherapy | Innovations | Medicine, Experimental | Genetic aspects | Gene expression | T cells | Health aspects | Epigenetic inheritance | Cell differentiation | Analysis | Animal models | Cytokines | Cytotoxicity | Lymphocytes T | Immunity (cell-mediated) | Proteins | CTLA-4 protein | Immune checkpoint | Lymphocytes | Epigenetics | Antitumor activity | Chemokines | Cancer | Index Medicus | Abridged Index Medicus
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9. Full Text Selective STAT3-α or -β expression reveals spliceform-specific phosphorylation kinetics, nuclear retention and distinct gene expression outcomes
by Ng, Ivan H. W and Ng, Dominic C. H and Jans, David A and Bogoyevitch, Marie A
Biochemical journal, ISSN 0264-6021, 10/2012, Volume 447, Issue 1, pp. 125 - 136
Signal transducer and activator of transcription 3 (STAT3) | Transcriptome analysis | Interleukin-6 (IL-6) | Nucleocytoplasmic trafficking | Transcription factor | Cytokine | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Mutagenesis, Site-Directed | Alternative Splicing | Gene Expression - drug effects | Humans | Cells, Cultured | DNA Primers - genetics | STAT3 Transcription Factor - chemistry | Gene Knockout Techniques | src Homology Domains | Animals | Cell Nucleus - metabolism | Base Sequence | HEK293 Cells | STAT3 Transcription Factor - deficiency | Mice | Kinetics | Phosphorylation - drug effects | Cell Nucleus - drug effects | Cytokines - pharmacology | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Tyrosine - chemistry | Amino Acid Substitution | Index Medicus | transcription factor | ERt, substrate-binding portion of the oestrogen receptor | WT, wild-type | HEK, human embryonic kidney | VP16, viral protein 16 | Fc, cytoplasmic fluorescence | interleukin-6 (IL-6) | gp130, glycoprotein 130 | DMEM, Dulbecco's modified Eagle's medium | signal transducer and activator of transcription 3 (STAT3) | 4-HT, 4-hydroxytamoxifen | MEF, murine embryonic fibroblast | iSTAT3, inducible specific STAT3 spliceform | cytokine | Fn, nuclear fluorescence | nucleocytoplasmic trafficking | GO, gene ontology | FBS, fetal bovine serum | STAT3, signal transducer and activator of transcription 3 | OSM, oncostatin M | CLSM, confocal laser-scanning microscopy | DAPI, 4′,6-diamidino-2-phenylindole | SHP, SH2 domain-containing protein tyrosine phosphatase | JAK, Janus kinase | IL, interleukin | Fc, ratio of nuclear to cytoplasmic fluorescence | SH2, Src homology 2 | Hsp90, heat-shock protein of 90 kDa | transcriptome analysis | MAPK, mitogen-activated protein kinase
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