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CANCER RESEARCH, ISSN 0008-5472, 07/2014, Volume 74, Issue 13, pp. 3408 - 3417
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8
Pharmacological treatment of recombinant growth differentiation factor 15 (GDF15) proteins reduces body weight in obese rodents and primates. Paradoxically,... 
ENERGY-BALANCE | HEART | ULCERATIVE DERMATITIS | DIET | MULTIDISCIPLINARY SCIENCES | GROWTH-DIFFERENTIATION FACTOR-15 | MACROPHAGE INHIBITORY CYTOKINE-1 | DISEASE | WEIGHT-LOSS | RECEPTOR | LIGAND
Journal Article
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE, ISSN 1553-4006, 2008, Volume 3, pp. 157 - 188
The past two decades have witnessed an explosion in Our understanding of pancreatic cancer, and it is now clear that pancreatic cancer is a disease of... 
targeted therapy | mouse model | DUCTAL ADENOCARCINOMA | MACROPHAGE INHIBITORY CYTOKINE-1 | GENE-EXPRESSION PROFILES | adenocarcinoma | ACUTE MYELOID-LEUKEMIA | PATHOLOGY | INTRAEPITHELIAL NEOPLASIA | MUTANT K-RAS | PAPILLARY MUCINOUS NEOPLASMS | ABERRANT METHYLATION | genetics | stem cell | carcinoma | pancreas | precursor | STEM-CELL ANTIGEN | TRANSGENIC MICE
Journal Article
Journal Article
Circulation, ISSN 0009-7322, 09/2012, Volume 126, Issue 13, pp. 1596 - 1604
Journal Article
Journal Article
Thorax, ISSN 0040-6376, 02/2019, Volume 74, Issue 2, pp. 164 - 176
IntroductionSkeletal muscle dysfunction is a clinically important complication of pulmonary arterial hypertension (PAH). Growth/differentiation factor 15... 
exercise | primary pulmonary hypertension | STATEMENT | TRIAL | QUADRICEPS STRENGTH | HOMEOSTASIS | RESPIRATORY SYSTEM | MACROPHAGE INHIBITORY CYTOKINE-1 | GROWTH | Skeletal Muscle | 2313 | 1506
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2017, Volume 23, Issue 10, pp. 1215 - 1219
Growth/differentiation factor 15 (GDF15), also known as MIC-1, is a distant member of the transforming growth factor-beta (TGF-beta) superfamily and has been... 
MEDICINE, RESEARCH & EXPERIMENTAL | GDNF FAMILY | MIC-1 | GENE | AMYLIN | INHIBITORY CYTOKINE-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | TGF-BETA SUPERFAMILY | WEIGHT | EXPRESSION | BINDING | CELL BIOLOGY | Surface Plasmon Resonance | Humans | Glial Cell Line-Derived Neurotrophic Factor Receptors - metabolism | Macaca fascicularis | Rats | Immunoblotting | Male | Weight Loss - drug effects | RNA, Messenger - metabolism | Eating - genetics | Glial Cell Line-Derived Neurotrophic Factor Receptors - genetics | Rats, Sprague-Dawley | Mice, Knockout | Obesity - metabolism | Brain - metabolism | Eating - drug effects | Animals | Flow Cytometry | HEK293 Cells | Growth Differentiation Factor 15 - pharmacology | Mice | Area Postrema - metabolism | Real-Time Polymerase Chain Reaction | Weight Loss - genetics | Cell metabolism | Cellular proteins | Cell receptors | Genetic aspects | Gene expression | Health aspects | Brain | Animal models | Interaction parameters | Transforming growth factor | Body weight | mRNA | Body weight loss | Area postrema | Rodents | Atherosclerosis | Heart diseases | Recombinant | Glial cell line-derived neurotrophic factor | Kidneys | Neurons | Diabetes mellitus | Cachexia | Metabolism | Biological activity | Signaling | Food intake | Arteriosclerosis | Minimum inhibitory concentration | Renal failure | Monoclonal antibodies | Hypophagia | Prostate cancer | Prostate | Cancer | Kidney transplantation
Journal Article
Carcinogenesis, ISSN 0143-3334, 03/2019, Volume 40, Issue 1, pp. 194 - 201
Genetically engineered murine models of Agl loss show that Agl deletion is permissive for bladder chemical carcinogenesis and provide the rationale for... 
GROWTH-FACTOR-BETA | UROPLAKINS | TGF-BETA | GLYCOGEN-STORAGE-DISEASE | BETA SUPERFAMILY MEMBER | ONCOLOGY | MACROPHAGE INHIBITORY CYTOKINE-1 | UROTHELIUM | CANCER | EXPRESSION | CARCINOMA | Index Medicus
Journal Article
Cancer Epidemiology Biomarkers and Prevention, ISSN 1055-9965, 01/2019, Volume 28, Issue 1, pp. 174 - 182
Background: Pancreatic cancer is a deadly disease for which available biomarkers, such as CA19-9, lack the desired sensitivity and specificity for early... 
DIAGNOSIS | OSTEOPONTIN | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | TUMOR-MARKERS | ONCOLOGY | ADENOCARCINOMA | MACROPHAGE INHIBITORY CYTOKINE-1 | PAPILLARY-MUCINOUS NEOPLASMS | POLYPEPTIDE SPECIFIC ANTIGEN | PROGRESSION | LESIONS
Journal Article
Canadian Journal of Cardiology, ISSN 0828-282X, 04/2019, Volume 35, Issue 4, pp. 462 - 470
Growth differentiation factor-15 (GDF-15) is a stress-inducible cytokine and member of the transforming growth factor-β cytokine superfamily that refines... 
POPULATION | CARDIAC & CARDIOVASCULAR SYSTEMS | MARKER | INHIBITORY CYTOKINE-1 | GROWTH-DIFFERENTIATION FACTOR-15 | RENAL-FUNCTION | VALIDATION | NATRIURETIC PEPTIDE
Journal Article
Oncotarget, ISSN 1949-2553, 11/2017, Volume 8, Issue 55, pp. 94393 - 94406
Expression of the inflammatory cytokine growth differentiation factor 15 (GDF15) is significantly elevated in many tumor types in association with epithelial... 
Signaling | Breast cancer | Invasion | CELLS | ACTIVATION | signaling | METASTASIS | GDF15 | MACROPHAGE INHIBITORY CYTOKINE-1 | breast cancer | RECEPTOR | EMT | CELL BIOLOGY | invasion | RESISTANCE | SUPERFAMILY | CONTRIBUTES
Journal Article