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1. Full Text Dextran derivative-based pH-sensitive liposomes for cancer immunotherapy
by Yuba, Eiji and Tajima, Naoki and Yoshizaki, Yuta and Harada, Atsushi and Hayashi, Hiroshi and Kono, Kenji
Biomaterials, ISSN 0142-9612, 2013, Volume 35, Issue 9, pp. 3091 - 3101
Advanced Basic Science | Dentistry | Dextran | Dendritic cell | PH-Sensitive liposome | Cellular immunity | Cytoplasmic delivery | Cancer immunotherapy | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Anhydrides - chemical synthesis | Fluorescence | Fluorescent Dyes - metabolism | Dextrans - chemistry | Immunity | Ovalbumin - metabolism | Anhydrides - chemistry | Neoplasms - therapy | Immunotherapy | Glutarates - chemical synthesis | Female | Glutarates - chemistry | Subcutaneous Tissue - pathology | T-Lymphocytes, Cytotoxic - immunology | Cell Line | Immunization | Antigens, Neoplasm - immunology | Chemical Precipitation | Mice, Inbred C57BL | Static Electricity | Particle Size | Dextrans - chemical synthesis | Liposomes - chemistry | Animals | Pyrenes - chemistry | Neoplasms - immunology | Titrimetry | Mice | Interferon-gamma - biosynthesis | Hydrogen-Ion Concentration | Care and treatment | Dendritic cells | Drug therapy | Hydrogen-ion concentration | Cancer | Antigens | Albumin | Index Medicus
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2. Full Text pH Biosensing by PI4P Regulates Cargo Sorting at the TGN
by Shin, John J.H and Liu, Peter and Chan, Leslie J and Ullah, Azmat and Pan, Jingxi and Borchers, Christoph H and Burke, John E and Stefan, Christopher and Smits, Gertien J and Loewen, Christopher J.R
Developmental cell, ISSN 1534-5807, 02/2020, Volume 52, Issue 4, pp. 461 - 476.e4
PI4P | pH biosensing | membrane contact sites | trans-Golgi Network | phosphatidylinositol 4-phosphate | Osh1 | PH domains | Tat2 | sterol trafficking | cytoplasmic pH | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Index Medicus
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3. Full Text A liposome-based antigen delivery system using pH-sensitive fusogenic polymers for cancer immunotherapy
by Yuba, Eiji and Harada, Atsushi and Sakanishi, Yuichi and Watarai, Shinobu and Kono, Kenji
Biomaterials, ISSN 0142-9612, 2012, Volume 34, Issue 12, pp. 3042 - 3052
Advanced Basic Science | Dentistry | Membrane fusion | Dendritic cell | Cytoplasmic delivery | Cellular immunity | Cancer immunotherapy | pH-sensitive liposome | PH-sensitive liposome | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | T-Lymphocytes, Cytotoxic - immunology | Cell Line | Polymers - administration & dosage | Mice, Inbred C57BL | Neoplasms, Experimental - therapy | Neoplasms, Experimental - pathology | Animals | Ovalbumin - administration & dosage | Immunotherapy | Female | Mice | Liposomes | Hydrogen-Ion Concentration | Antigens | Usage | Care and treatment | Biological products | Dendritic cells | Albumin | Universities and colleges | Polymer industry | Polymers | T cells | Cancer | Index Medicus
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4. Full Text Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias
by Walker, Christopher J and Walker, Christopher J and Oaks, Joshua J and Oaks, Joshua J and Santhanam, Ramasamy and Santhanam, Ramasamy and Neviani, Paolo and Neviani, Paolo and Harb, Jason G and Harb, Jason G and Ferenchak, Gregory and Ferenchak, Gregory and Ellis, Justin J and Ellis, Justin J and Landesman, Yosef and Landesman, Yosef and Eisfeld, Ann-Kathrin and Eisfeld, Ann-Kathrin and Gabrail, Nash Y and Gabrail, Nash Y and Smith, Carrie L and Smith, Carrie L and Caligiuri, Michael A and Caligiuri, Michael A and Hokland, Peter and Hokland, Peter and Roy, Denis Claude and Roy, Denis Claude and Reid, Alistair and Reid, Alistair and Milojkovic, Dragana and Milojkovic, Dragana and Goldman, John M and Goldman, John M and Apperley, Jane and Apperley, Jane and Garzon, Ramiro and Garzon, Ramiro and Marcucci, Guido and Marcucci, Guido and Shacham, Sharon and Shacham, Sharon and Kauffman, Michael G and Kauffman, Michael G and Perrotti, Danilo and Perrotti, Danilo
Blood, ISSN 0006-4971, 2013, Volume 122, Issue 17, pp. 3034 - 3044
Life Sciences & Biomedicine | Hematology | Science & Technology | Antigens, CD34 - metabolism | Apoptosis - drug effects | Histone Chaperones - genetics | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Histone Chaperones - metabolism | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics | Male | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Adult | Ribonucleoproteins - genetics | Antineoplastic Agents - pharmacology | Drug Evaluation, Preclinical | Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology | Hydrazines - pharmacology | Gene Expression Regulation, Leukemic - drug effects | Transcription Factors - antagonists & inhibitors | Receptors, Cytoplasmic and Nuclear - genetics | Ribonucleoproteins - metabolism | Transcription Factors - genetics | Histone Chaperones - antagonists & inhibitors | Protein Transport | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | Ribonucleoproteins - antagonists & inhibitors | Transcription Factors - metabolism | Triazoles - pharmacology | Fusion Proteins, bcr-abl - genetics | Animals | Karyopherins - metabolism | Receptors, Cytoplasmic and Nuclear - antagonists & inhibitors | Fusion Proteins, bcr-abl - antagonists & inhibitors | Karyopherins - genetics | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Antigens, CD34 - genetics | Karyopherins - antagonists & inhibitors | Clinical Trials, Phase I as Topic | Fusion Proteins, bcr-abl - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Index Medicus | Abridged Index Medicus | 33 | Myeloid Neoplasia
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5. Full Text TORC1 signaling regulates cytoplasmic pH through Sir2 in yeast
by Devare, Mayur Nimbadas and Kim, Yeong Hyeock and Jung, Joohye and Kang, Woo Kyu and Kwon, Ki‐Sun and Kim, Jeong‐Yoon
Aging cell, ISSN 1474-9718, 06/2020, Volume 19, Issue 6, pp. e13151 - n/a
Sir2 | TORC1 | aging | Pma1 | Saccharomyces cerevisiae | cytoplasmic pH | Life Sciences & Biomedicine | Geriatrics & Gerontology | Science & Technology | Cell Biology | Protein kinase A | Phosphorylation | Phenotypes | Nitrogen sources | Phosphoprotein phosphatase | Cyclic AMP | Rapamycin | Phosphatase | pH effects | Kinases | Casein kinase II | Mutants | NAD | Proteins | Life span | Casein | Protein phosphatase | Index Medicus | Original Paper
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6. Full Text Structural basis for pH gating of plant aquaporins
by Frick, Anna and Järvå, Michael and Törnroth-Horsefield, Susanna and Institutionen för kemi och molekylärbiologi and Naturvetenskapliga fakulteten and Faculty of Sciences and Göteborgs universitet and Gothenburg University and Department of Chemistry and Molecular Biology
FEBS letters, ISSN 0014-5793, 04/2013, Volume 587, Issue 7, pp. 989 - 993
X-ray crystallography | Membrane protein | pH gating | Plasma membrane intrinsic protein | Aquaporin | AQP | PIP | plasma membrane intrinsic protein | aquaporin | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Aquaporins - chemistry | Crystallography, X-Ray | Spinacia oleracea - metabolism | Histidine - metabolism | Aquaporins - genetics | Biological Transport | Plant Proteins - chemistry | Spinacia oleracea - genetics | Cell Membrane - metabolism | Plant Proteins - metabolism | Recombinant Proteins - metabolism | Protein Structure, Secondary | Water - metabolism | Histidine - genetics | Models, Molecular | Recombinant Proteins - chemistry | Aquaporins - metabolism | Binding Sites - genetics | Cytosol - chemistry | Plant Proteins - genetics | Cytosol - metabolism | Protein Conformation | Mutation | Histidine - chemistry | Hydrogen-Ion Concentration | Histidine | Structure | Hydrogen-ion concentration | Aquaporins | Crystals | Index Medicus | stress | permeability | transport | divalent-cations | Chemical Sciences | water channel activity | plasma-membrane | cells | Kemi | cytoplasmic | protons | phosphorylation
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7. Full Text The application of pH-sensitive polymer-lipids to antigen delivery for cancer immunotherapy
by Yuba, Eiji and Kono, Yoshikazu and Harada, Atsushi and Yokoyama, Shoichi and Arai, Masaya and Kubo, Kazuhiro and Kono, Kenji
Biomaterials, ISSN 0142-9612, 2013, Volume 34, Issue 22, pp. 5711 - 5721
Advanced Basic Science | Dentistry | Dendritic cell | Cytoplasmic delivery | Cellular immunity | Cancer immunotherapy | pH-sensitive polymer | pH-sensitive liposome | Engineering | Materials Science | Technology | Engineering, Biomedical | Materials Science, Biomaterials | Science & Technology | Antigens | Cell Line | Immunization | Immunotherapy - methods | Temperature | Ovalbumin - immunology | Polymers - chemical synthesis | Mice, Inbred C57BL | Rhodamines - metabolism | Immunity | Lipids - chemistry | Liposomes - chemistry | Neoplasms - therapy | Animals | Lipids - chemical synthesis | Arylsulfonates - chemistry | Neoplasms - immunology | Female | Polymers - chemistry | Mice | Phycoerythrin - metabolism | Phosphatidylethanolamines - chemistry | Hydrogen-Ion Concentration | Care and treatment | Dendritic cells | Immunotherapy | Lipids | Polymer industry | Polymers | Hydrogen-ion concentration | Cancer | Index Medicus
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8. Full Text Molecular Mechanism of Membrane Binding of the GRP1 PH Domain
by Lai, Chun-Liang and Srivastava, Anand and Pilling, Carissa and Chase, Anna R and Falke, Joseph J and Voth, Gregory A
Journal of molecular biology, ISSN 0022-2836, 09/2013, Volume 425, Issue 17, pp. 3073 - 3090
peripheral membrane protein | pleckstrin homology domain | membrane targeting | phosphatidylinositol-3,4,5-trisphosphate or PIP3 | anionic lipids | phosphatidylinositol-3,4,5-trisphosphate or PIP | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | Phosphatidylinositol Phosphates - metabolism | Phosphatidylserines - metabolism | Phosphatidylserines - chemistry | Models, Molecular | Phospholipids - chemistry | Blood Proteins - chemistry | Blood Proteins - metabolism | Phosphoproteins - metabolism | Static Electricity | Molecular Dynamics Simulation | Phosphatidylinositol Phosphates - chemistry | Phosphoproteins - chemistry | Membrane Proteins - chemistry | Receptors, Cytoplasmic and Nuclear - chemistry | Protein Binding | Cell Membrane - metabolism | Membrane Proteins - metabolism | Kinetics | Lipid Bilayers - chemistry | Lipid Bilayers - metabolism | Phospholipids - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Fluorescence | Lipids | Chemical properties | Surface active agents | Analysis | Protein binding | Index Medicus
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9. Full Text The enhanced cyan fluorescent protein: a sensitive pH sensor for fluorescence lifetime imaging
by Poëa-Guyon, Sandrine and Pasquier, Hélène and Mérola, Fabienne and Morel, Nicolas and Erard, Marie
Analytical and bioanalytical chemistry, ISSN 1618-2642, 5/2013, Volume 405, Issue 12, pp. 3983 - 3987
Biochemistry, general | Food Science | Fluorescent protein | Enhanced cyan fluorescent protein or ECFP | FLIM | Laboratory Medicine | pH sensor | PC12 cells | Chemistry | Analytical Chemistry | Characterization and Evaluation of Materials | Granular pH | Environmental Monitoring/Analysis | PH sensor | Biochemistry & Molecular Biology | Physical Sciences | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Green Fluorescent Proteins - analysis | Fluorescent Dyes - analysis | Recombinant Fusion Proteins - analysis | Fluorescent Dyes - metabolism | Rats | Green Fluorescent Proteins - genetics | Cytoplasmic Granules - chemistry | PC12 Cells | Microscopy, Confocal | Animals | Recombinant Fusion Proteins - genetics | Biosensing Techniques - methods | Chromogranin A - analysis | Chromogranin A - genetics | Hydrogen-Ion Concentration | Physiological aspects | Research | Hydrogen-ion concentration | Fluorescent proteins | Methods | Imaging systems | Index Medicus | Proteins | Granular materials | Imaging | Fluorescence | Sensors | Ammonium chlorides | Quantitative analysis | Green Fluorescent Proteins | Chromogranin A | Cytoplasmic Granules | Neurons and Cognition | Psychology and behavior | Neurobiology | Recombinant Fusion Proteins | Life Sciences | Biosensing Techniques | Cognitive Sciences | Fluorescent Dyes
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