Articles

UofT Libraries is getting a new library services platform in January 2021.
Learn more about the change.

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (1657) 1657
Newsletter (52) 52
Book Chapter (28) 28
Newspaper Article (9) 9
Dissertation (8) 8
Magazine Article (2) 2
Book / eBook (1) 1
Government Document (1) 1
Publication (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (1282) 1282
cachexia (1186) 1186
life sciences & biomedicine (1139) 1139
humans (830) 830
animals (808) 808
cancer (586) 586
male (530) 530
mice (491) 491
cachexia - etiology (389) 389
female (376) 376
oncology (318) 318
cachexia - metabolism (315) 315
research (266) 266
musculoskeletal system (243) 243
muscles (240) 240
biological and medical sciences (238) 238
muscle, skeletal - metabolism (227) 227
proteins (220) 220
cytokines (217) 217
tumors (217) 217
cell biology (214) 214
skeletal muscle (213) 213
inflammation (209) 209
cachexia - pathology (205) 205
cancer cachexia (201) 201
gene expression (199) 199
metabolism (196) 196
cachexia - genetics (190) 190
medical sciences (182) 182
body weight (180) 180
health aspects (179) 179
muscle, skeletal - pathology (178) 178
physiological aspects (178) 178
analysis (177) 177
cachexia - physiopathology (177) 177
neoplasms - complications (171) 171
middle aged (168) 168
physiology (165) 165
aged (163) 163
disease models, animal (163) 163
biochemistry & molecular biology (156) 156
rodents (149) 149
sarcopenia (144) 144
anorexia (143) 143
science & technology - other topics (143) 143
multidisciplinary sciences (142) 142
research article (140) 140
atrophy (138) 138
signal transduction (136) 136
genetic aspects (135) 135
rats (132) 132
weight loss (131) 131
care and treatment (130) 130
medicine (127) 127
cachexia - drug therapy (125) 125
mice, inbred c57bl (118) 118
patients (115) 115
quality of life (115) 115
general & internal medicine (108) 108
cancer therapies (107) 107
cell line, tumor (107) 107
endocrinology & metabolism (106) 106
medicine, general & internal (105) 105
muscle wasting (105) 105
geriatrics & gerontology (98) 98
medical research (97) 97
science (97) 97
review (96) 96
adult (95) 95
nutrition & dietetics (92) 92
neoplasms - metabolism (91) 91
chemotherapy (89) 89
development and progression (89) 89
obesity (89) 89
studies (89) 89
cachexia - complications (88) 88
medicine, research & experimental (88) 88
research & experimental medicine (88) 88
kinases (87) 87
nutrition (86) 86
body mass index (84) 84
mice, knockout (84) 84
mortality (84) 84
risk factors (84) 84
immunology (81) 81
prognosis (81) 81
adipose tissue (80) 80
muscular atrophy - metabolism (80) 80
body composition (77) 77
apoptosis (76) 76
pancreatic cancer (76) 76
medical prognosis (75) 75
mice, inbred balb c (74) 74
muscle proteins - metabolism (73) 73
muscle, skeletal - drug effects (72) 72
fundamental and applied biological sciences. psychology (71) 71
physical fitness (71) 71
rna, messenger - genetics (71) 71
abridged index medicus (70) 70
heart failure (70) 70
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1738) 1738
French (6) 6
Japanese (4) 4
Chinese (3) 3
German (3) 3
Portuguese (3) 3
Norwegian (2) 2
Spanish (2) 2
Catalan (1) 1
Croatian (1) 1
Danish (1) 1
Italian (1) 1
Russian (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia
by Roberts, Edward W and Deonarine, Andrew and Jones, James O and Denton, Alice E and Feig, Christine and Lyons, Scott K and Espeli, Marion and Kraman, Matthew and McKenna, Brendan and Wells, Richard J.B and Zhao, Qi and Caballero, Otavia L and Larder, Rachel and Coll, Anthony P and O'Rahilly, Stephen and Brindle, Kevin M and Teichmann, Sarah A and Tuveson, David A and Fearon, Douglas T
The Journal of experimental medicine, ISSN 0022-1007, 06/2013, Volume 210, Issue 6, pp. 1137 - 1151
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Neoplasms - metabolism | Follistatin - genetics | Lymphopoiesis - genetics | Follistatin - metabolism | Anemia - pathology | Muscle, Skeletal - metabolism | Mice, Transgenic - metabolism | Muscle, Skeletal - cytology | Adipose Tissue - metabolism | Anemia - genetics | Chemokine CXCL12 - genetics | Neoplasms - genetics | Bone Marrow - metabolism | Gelatinases - metabolism | Serine Endopeptidases - genetics | Membrane Proteins - metabolism | Cachexia - metabolism | Cell Lineage - genetics | Erythropoiesis - genetics | Muscular Disorders, Atrophic - metabolism | Cachexia - genetics | Membrane Proteins - genetics | Mice, Inbred C57BL | Stromal Cells - metabolism | Mice, Transgenic - genetics | Muscular Disorders, Atrophic - genetics | Hematopoiesis - genetics | Transcriptome - genetics | Pancreas - metabolism | Anemia - metabolism | Animals | Chemokine CXCL12 - metabolism | Gelatinases - genetics | Cachexia - pathology | Mice | Serine Endopeptidases - metabolism | Stromal Cells - cytology | Index Medicus | 307
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Inhibition of Stat3 activation suppresses caspase-3 and the ubiquitin-proteasome system, leading to preservation of muscle mass in cancer cachexia
by Silva, Kleiton Augusto Santos and Dong, Jiangling and Dong, Yanjun and Dong, Yanlan and Schor, Nestor and Tweardy, David J and Zhang, Liping and Mitch, William E
The Journal of biological chemistry, ISSN 0021-9258, 04/2015, Volume 290, Issue 17, pp. 11177 - 11187
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Colonic Neoplasms - genetics | SKP Cullin F-Box Protein Ligases - genetics | Caspase 3 - metabolism | Ubiquitin - metabolism | Muscle, Skeletal - metabolism | Colonic Neoplasms - metabolism | Tripartite Motif Proteins | Proteolysis | Caspase 3 - genetics | Muscle Proteins - metabolism | Myostatin - genetics | CCAAT-Enhancer-Binding Protein-delta - metabolism | Myostatin - metabolism | Cachexia - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Cachexia - genetics | Ubiquitin-Protein Ligases - metabolism | SKP Cullin F-Box Protein Ligases - metabolism | Ubiquitin - genetics | Carcinoma, Lewis Lung - metabolism | Mice, Knockout | Muscle Proteins - genetics | Proteasome Endopeptidase Complex - genetics | Animals | Carcinoma, Lewis Lung - genetics | CCAAT-Enhancer-Binding Protein-delta - genetics | Cachexia - pathology | Colonic Neoplasms - pathology | Carcinoma, Lewis Lung - pathology | Cell Line, Tumor | Mice | Muscle, Skeletal - pathology | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics | Index Medicus | Ubiquitin | Signal Transduction | STAT3 | Caspase | Cancer Cachexia | Cancer Biology | Muscle Atrophy | Caspase-3
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Elevated expression of activins promotes muscle wasting and cachexia
by Chen, Justin L and Walton, Kelly L and Winbanks, Catherine E and Murphy, Kate T and Thomson, Rachel E and Makanji, Yogeshwar and Qian, Hongwei and Lynch, Gordon S and Harrison, Craig A and Gregorevic, Paul
The FASEB journal, ISSN 0892-6638, 04/2014, Volume 28, Issue 4, pp. 1711 - 1723
atrophy | adeno‐associated virus | myostatin | Atrophy | Myostatin | Adeno-associated virus | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Activin Receptors, Type II - metabolism | Dependovirus - genetics | SKP Cullin F-Box Protein Ligases - genetics | Humans | Activins - metabolism | Muscle, Skeletal - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - genetics | MCF-7 Cells | Muscle Proteins - metabolism | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Myostatin - genetics | Cachexia - metabolism | Gene Expression | Cachexia - genetics | Muscular Atrophy - metabolism | Myostatin - deficiency | Mice, Inbred C57BL | Muscular Atrophy - genetics | SKP Cullin F-Box Protein Ligases - metabolism | Signal Transduction - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Genetic Vectors - genetics | Mice, Knockout | Muscle Proteins - genetics | Animals | Activin Receptors, Type II - genetics | Cell Line, Tumor | Activins - genetics | Mice | Activins - blood | Muscle, Skeletal - pathology | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing
by Gatto, Sole and Gagliardi, Miriam and Franzese, Monica and Leppert, Sylwia and Papa, Mariarosaria and Cammisa, Marco and Grillo, Giacomo and Velasco, Guillame and Francastel, Claire and Toubiana, Shir and D'Esposito, Maurizio and Angelini, Claudia and Matarazzo, Maria R
Nucleic acids research, ISSN 0305-1048, 2017, Volume 45, Issue 10, pp. 5739 - 5756
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Immunologic Deficiency Syndromes - pathology | RNA, Messenger - immunology | Alternative Splicing | Skin Diseases - genetics | Epigenesis, Genetic | Eye Abnormalities - immunology | Humans | Male | Anorexia - genetics | Skin Diseases - pathology | Leukocyte Common Antigens - immunology | DNA Methylation | Facies | Female | Transcription, Genetic | B-Lymphocytes - pathology | Immunologic Deficiency Syndromes - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology | Promoter Regions, Genetic | Cachexia - genetics | Histones - immunology | RNA, Messenger - genetics | Skin Diseases - immunology | Tumor Necrosis Factor Receptor Superfamily, Member 7 - genetics | Eye Abnormalities - genetics | Anorexia - pathology | Anorexia - immunology | DNA (Cytosine-5-)-Methyltransferases - genetics | B-Lymphocytes - immunology | Histones - genetics | Eye Abnormalities - pathology | Cachexia - pathology | Cachexia - immunology | CpG Islands | Immunologic Deficiency Syndromes - genetics | Immunologic Memory | Leukocyte Common Antigens - genetics | Mutation | DNA (Cytosine-5-)-Methyltransferases - immunology | Cell Line, Transformed | Index Medicus | Life Sciences | Gene regulation, Chromatin and Epigenetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Autophagy is induced in the skeletal muscle of cachectic cancer patients
by Aversa, Zaira and Pin, Fabrizio and Lucia, Simone and Penna, Fabio and Verzaro, Roberto and Fazi, Maurizio and Colasante, Giuseppina and Tirone, Andrea and Fanelli, Filippo Rossi and Ramaccini, Cesarina and Costelli, Paola and Muscaritoli, Maurizio
Scientific reports, ISSN 2045-2322, 07/2016, Volume 6, Issue 1, pp. 30340 - 30340
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasms - metabolism | Protein Kinases - metabolism | Protein Kinases - genetics | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Gene Expression Regulation, Neoplastic | Male | Muscle, Skeletal - metabolism | RNA, Messenger - metabolism | Autophagy | Case-Control Studies | Neoplasms - complications | Neoplasms - genetics | Tumor Suppressor Proteins - genetics | Cachexia - etiology | Female | Membrane Proteins - metabolism | Cachexia - metabolism | Proto-Oncogene Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Cachexia - genetics | Membrane Proteins - genetics | RNA, Messenger - genetics | Proto-Oncogene Proteins - genetics | Proto-Oncogene Proteins c-myc - metabolism | Beclin-1 - genetics | Aged | Proto-Oncogene Proteins c-myc - genetics | Beclin-1 - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia
by Andrea Bonetto and Tufan Aydogdu and Xiaoling Jin and Zongxiu Zhang and Rui Zhan and Leopold Puzis and Leonidas G. Koniaris and Teresa A. Zimmers
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 08/2012, Volume 303, Issue 3, pp. 410 - 421
Signal transducer and activator of transcription | Incb018424 | Electroporation | Inhibitory peptide | T cell protein tyrosine phosphatase/ protein tyrosine phosphatase | Janus-activated kinase | Interleukin-6 | Atrophy | Burn | Suppressors of cytokine signaling 3 | Lipopolysaccharide | Sepsis | Nonreceptor type 2 | Endocrinology & Metabolism | Physiology | Life Sciences & Biomedicine | Science & Technology | Neoplasms - metabolism | Wasting Syndrome - prevention & control | Wasting Syndrome - metabolism | Cricetulus | Male | Muscle, Skeletal - metabolism | Janus Kinases - metabolism | Neoplasms - complications | Neoplasms - genetics | Muscle, Skeletal - drug effects | Cachexia - etiology | Interleukin-6 - physiology | Female | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | CHO Cells | Disease Models, Animal | Pyrazoles - pharmacology | Cricetinae | Cachexia - genetics | Interleukin-6 - genetics | Janus Kinases - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Mutant Proteins - genetics | Mice, Transgenic | Signal Transduction - genetics | Wasting Syndrome - genetics | Cachexia - prevention & control | Mutant Proteins - administration & dosage | Neoplasms - drug therapy | Janus Kinases - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | Signal Transduction - drug effects | Mice, Nude | Cachexia - pathology | Mice | Protein Kinase Inhibitors - pharmacology | Muscle, Skeletal - pathology | RNA, Small Interfering - administration & dosage | STAT3 Transcription Factor - antagonists & inhibitors | Wasting Syndrome - pathology | Transcription factors | Control | Analysis | Muscles | Genetic aspects | Wasting syndrome | Musculoskeletal system | Inhibitor drugs | Cytokines | Ligands | Metabolic disorders | Cancer | Index Medicus | incb018424 | protein tyrosine phosphatase, nonreceptor type 2 | burn | suppressors of cytokine signaling 3 | atrophy | signal transducer and activator of transcription 3 inhibitory peptide | electroporation | T cell protein tyrosine phosphatase | lipopolysaccharide | interleukin-6 | sepsis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text A key role for leukemia inhibitory factor in C26 cancer cachexia
by Seto, Danielle N and Kandarian, Susan C and Jackman, Robert W
The Journal of biological chemistry, ISSN 0021-9258, 08/2015, Volume 290, Issue 32, pp. 19976 - 19986
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Luciferases - metabolism | Transcription Factor AP-1 - genetics | Gene Expression Regulation, Neoplastic | Culture Media, Conditioned - pharmacology | Male | Green Fluorescent Proteins - genetics | Leukemia Inhibitory Factor - genetics | Muscle Fibers, Skeletal - drug effects | Muscle Fibers, Skeletal - metabolism | Transcription Factor AP-1 - metabolism | Colonic Neoplasms - metabolism | Leukemia Inhibitory Factor - metabolism | Luciferases - genetics | Oncostatin M - antagonists & inhibitors | Adenocarcinoma - metabolism | Janus Kinase 2 - metabolism | Oncostatin M - metabolism | Adenocarcinoma - genetics | Leukemia Inhibitory Factor - antagonists & inhibitors | Phosphorylation - drug effects | Cachexia - metabolism | Genes, Reporter | Janus Kinase 2 - antagonists & inhibitors | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Green Fluorescent Proteins - metabolism | Cachexia - genetics | Signal Transduction | Janus Kinase 2 - genetics | Antibodies, Neutralizing - pharmacology | Cell Size | Animals | Cachexia - pathology | Colonic Neoplasms - pathology | Muscle Fibers, Skeletal - pathology | Cell Line, Tumor | Mice | Protein Kinase Inhibitors - pharmacology | Oncostatin M - genetics | Index Medicus | C26 colon carcinoma | leukemia inhibitory factor (LIF) | Molecular Bases of Disease | colorectal cancer | JAK | STAT3 | cancer cachexia | muscle atrophy | skeletal muscle
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text SIRT1 protein, by blocking the activities of transcription factors FoxO1 and FoxO3, inhibits muscle atrophy and promotes muscle growth
by Lee, Donghoon and Goldberg, Alfred L
The Journal of biological chemistry, ISSN 0021-9258, 10/2013, Volume 288, Issue 42, pp. 30515 - 30526
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | SKP Cullin F-Box Protein Ligases - genetics | Male | Phosphatidylinositol 3-Kinases - metabolism | Sirtuin 1 - genetics | Proto-Oncogene Proteins c-akt - genetics | Tripartite Motif Proteins | Forkhead Transcription Factors - metabolism | Muscle Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cachexia - metabolism | Cachexia - genetics | Fasting | Muscle, Skeletal - growth & development | Muscular Atrophy - metabolism | Signal Transduction | Muscular Atrophy - pathology | Sirtuin 1 - biosynthesis | Ubiquitin-Protein Ligases - metabolism | Muscular Atrophy - genetics | SKP Cullin F-Box Protein Ligases - metabolism | Forkhead Transcription Factors - genetics | Muscle Proteins - genetics | Phosphatidylinositol 3-Kinases - genetics | Animals | Cachexia - pathology | Forkhead Box Protein O1 | Mice | Muscle, Skeletal - pathology | Forkhead Box Protein O3 | Ubiquitin-Protein Ligases - genetics | Index Medicus | Deacetylase | FoxO | Skeletal Muscle | Muscle Atrophy | Sirt1 | Transcription Factors | FoxO3 | Cell Biology | Hypertrophy
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Spartan deficiency causes genomic instability and progeroid phenotypes
by Maskey, R.S and Kim, M.S and Baker, D.J and Childs, B and Malureanu, L.A and Jeganathan, K.B and Machida, Y and Deursen, J.M.A. van and Machida, Y.J
Nature communications, ISSN 2041-1723, 2014, Volume 5, Issue 1, pp. 5744 - 5744
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cachexia - complications | Genomic Instability | Cataract - pathology | Male | Progeria - metabolism | DNA-Binding Proteins - deficiency | Genes, Lethal | Lordosis - genetics | Proliferating Cell Nuclear Antigen - genetics | Progeria - pathology | Cell Death | Female | Integrases - metabolism | Lordosis - metabolism | Cachexia - metabolism | Chromatin - chemistry | Fibroblasts - metabolism | Cellular Senescence - genetics | Micronuclei, Chromosome-Defective | Gene Expression | Cachexia - genetics | Signal Transduction | DNA Replication | Gene Dosage | Progeria - genetics | Cataract - metabolism | Chromatin - pathology | DNA-Binding Proteins - genetics | Fibroblasts - pathology | Chromosomal Proteins, Non-Histone - deficiency | Chromosomal Proteins, Non-Histone - genetics | Mice, Knockout | Cataract - complications | Animals | Lordosis - complications | Cachexia - pathology | Cataract - genetics | Mice | Lordosis - pathology | Progeria - complications | Proliferating Cell Nuclear Antigen - metabolism | Integrases - genetics | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights