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Molecular Cancer Research, ISSN 1541-7786, 12/2012, Volume 10, Issue 12, pp. 1597 - 1606
To understand the mechanisms leading to trastuzumab resistance in HER2-overexpressing breast tumors, we created trastuzumab-insensitive cell lines (SKBR3/100-8... 
MIGRATION | STEM-CELLS | INVASION | GROWTH-FACTOR-RECEPTOR | MECHANISM | LIGANDS | ONCOLOGY | HERCEPTIN | MESENCHYMAL TRANSITION | BETA-CATENIN | CONTRIBUTES | CELL BIOLOGY | Receptor, Epidermal Growth Factor - genetics | Cadherins - metabolism | Receptor, ErbB-2 - genetics | Humans | Transcriptional Activation | Receptor, ErbB-2 - metabolism | Drug Resistance, Neoplasm | Cadherins - biosynthesis | Wnt3 Protein - genetics | Breast Neoplasms - metabolism | Wnt3 Protein - biosynthesis | beta Catenin - biosynthesis | Breast Neoplasms - enzymology | Receptor, Epidermal Growth Factor - metabolism | Nuclear Proteins - biosynthesis | Antibodies, Monoclonal, Humanized - pharmacology | Female | Wnt3 Protein - metabolism | Twist-Related Protein 1 - biosynthesis | Cadherins - genetics | Nuclear Proteins - genetics | Snail Family Transcription Factors | Wnt Signaling Pathway | Receptor, Epidermal Growth Factor - biosynthesis | Receptor, ErbB-2 - biosynthesis | Organic Cation Transport Proteins - metabolism | Nuclear Proteins - metabolism | Transcription Factors - biosynthesis | Transcription Factors - genetics | Organic Cation Transport Proteins - biosynthesis | beta Catenin - metabolism | beta Catenin - genetics | Transcription Factors - metabolism | Phenotype | Breast Neoplasms - genetics | Twist-Related Protein 1 - genetics | Cell Line, Tumor | Organic Cation Transport Proteins - genetics | Twist-Related Protein 1 - metabolism | Trastuzumab | Index Medicus | trastuzumab | β-catenin | EMT | Breast Cancer | Wnt3
Journal Article
Experimental Cell Research, ISSN 0014-4827, 04/2014, Volume 323, Issue 1, pp. 87 - 99
Promising renal replacement therapies include the development of a bioartificial kidney using functional human kidney cell models. In this study, human... 
Regenerative nephrology | Transport | ECM | Bioartificial kidney | MORTALITY | ORGANIC ANION TRANSPORTER | INJURY | P-GLYCOPROTEIN | TRANSPLANTATION | CELL BIOLOGY | INDIVIDUALS | EPITHELIAL-CELLS | ONCOLOGY | PROTEINS | EXPRESSION | STAGE RENAL-DISEASE | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Fibronectins - biosynthesis | Urine - cytology | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Kidneys, Artificial | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Multidrug Resistance-Associated Proteins - biosynthesis | Neoplasm Proteins - metabolism | Cadherins - biosynthesis | Bioartificial Organs | Octamer Transcription Factor-2 - antagonists & inhibitors | ATP-Binding Cassette Transporters - metabolism | Transendothelial and Transepithelial Migration - physiology | Cell Culture Techniques | Tissue Engineering | Cell Line | Kidney Tubules, Proximal - cytology | Collagen Type I - metabolism | Cell Adhesion Molecules - biosynthesis | Neoplasm Proteins - biosynthesis | ATP-Binding Cassette, Sub-Family B, Member 1 - biosynthesis | ATP-Binding Cassette Transporters - biosynthesis | Collagen Type I - biosynthesis | Octamer Transcription Factor-2 - metabolism | Octamer Transcription Factor-2 - biosynthesis | Inulin - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Phosphates | Fibronectins | Collagen | Physiological aspects | Drug resistance | Comparative analysis | Gene expression | Urine | Kidneys | Cellular biology | Morphology | Index Medicus
Journal Article
Anticancer Research, ISSN 0250-7005, 08/2016, Volume 36, Issue 8, pp. 3997 - 4005
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 1/2014, Volume 143, Issue 2, pp. 265 - 276
We investigated the expression of –CXC chemokine ligand 13 (CXCL13) and its receptor –CXC chemokine receptor 5 (CXCR5) in 98 breast cancer (BC) patients with... 
Lymph node metastasis | Epithelial to mesenchymal transition | RANKL | Medicine & Public Health | CXCR5 | Oncology | Breast cancer | CXCL13 | ANGIOGENESIS | TUMOR | CXCR5 CHEMOKINE RECEPTOR | NEUROBLASTOMA-CELLS | INVASION | MELANOMA | ONCOLOGY | MAMMARY-GLAND DEVELOPMENT | PROSTATE-CANCER | TRANSCRIPTIONAL REGULATION | EXPRESSION | Antigens, CD - biosynthesis | Furans - pharmacology | Humans | Middle Aged | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Cadherins - biosynthesis | RNA, Messenger - biosynthesis | Lymphatic Metastasis - pathology | Epithelial-Mesenchymal Transition | Biomarkers, Tumor - metabolism | Adult | Female | Indoles - pharmacology | Snail Family Transcription Factors | Chemokine CXCL13 - antagonists & inhibitors | Matrix Metalloproteinase 9 - biosynthesis | Receptors, CXCR5 - metabolism | Signal Transduction | Vimentin - biosynthesis | src-Family Kinases - antagonists & inhibitors | Transcription Factors - biosynthesis | RANK Ligand - biosynthesis | Pyrimidines - pharmacology | Sulfonamides - pharmacology | RANK Ligand - genetics | Receptors, CXCR5 - antagonists & inhibitors | Breast Neoplasms - pathology | Chemokine CXCL13 - biosynthesis | Chemokine CXCL13 - metabolism | Cell Line, Tumor | Receptors, CXCR5 - biosynthesis | Aged | Pyridines - pharmacology | Cell Movement | Metastasis | Gene expression | Health aspects | Intermediate filament proteins | Stem cells | Index Medicus
Journal Article
Cell and Tissue Research, ISSN 0302-766X, 10/2015, Volume 362, Issue 1, pp. 45 - 60
Glioblastoma multiforme (GBM) is the most common and aggressive malignant primary brain tumor in humans, whose invasiveness and proliferation are associated... 
Human Genetics | Biomedicine | N-cadherin | Proteomics | Molecular Medicine | Matrix metalloproteinase | ADAM-10 | Glioblastoma multiforme | Glial tumors | RECEPTOR | BETA-CATENIN | CELL BIOLOGY | MALIGNANT GLIOMA | IN-VITRO | HEPATOCELLULAR-CARCINOMA | INVASION | INHIBITION | SIGNALING PATHWAY | CELL-MIGRATION | PERITUMOR TISSUE | Immunohistochemistry | Amyloid Precursor Protein Secretases - genetics | Glioblastoma - enzymology | Antigens, CD - biosynthesis | Humans | Brain Neoplasms - pathology | Antigens, CD - genetics | Cadherins - biosynthesis | Brain Neoplasms - metabolism | Case-Control Studies | ADAM Proteins - biosynthesis | RNA, Messenger - biosynthesis | Glioblastoma - genetics | Matrix Metalloproteinase 9 - genetics | Glioblastoma - metabolism | Cadherins - genetics | Matrix Metalloproteinase 2 - biosynthesis | Brain Neoplasms - enzymology | Matrix Metalloproteinase 9 - biosynthesis | Membrane Proteins - genetics | RNA, Messenger - genetics | ADAM10 Protein | Brain Neoplasms - genetics | Matrix Metalloproteinase 2 - genetics | Membrane Proteins - biosynthesis | Glioblastoma - pathology | Cell Line, Tumor | Biomarkers, Tumor - genetics | ADAM Proteins - genetics | Biomarkers, Tumor - biosynthesis | Amyloid Precursor Protein Secretases - biosynthesis | Prognosis | Chemical properties | RNA | Health aspects | Cell growth | Metastasis | Proteases | Brain cancer | Cell adhesion & migration | Index Medicus
Journal Article
Oncology Reports, ISSN 1021-335X, 1/2014, Volume 31, Issue 1, pp. 73 - 78
Although ZNF746, also known as Parkin-interacting substrate (PARIS), has been reported to suppress peroxisome proliferator-activated receptor γ coactivator-1α... 
H460 lung cancer | Twist | invasion | ZNF746 | epithelial to mesenchymal transition | matrix metalloproteinase | E-cadherin | Epithelial to mesenchymal transition | Matrix metalloproteinase | Invasion | METASTASIS | ADENOCARCINOMA | SENSITIVITY | MODEL | BREAST-CANCER | OCT4 | IN-VITRO | ONCOLOGY | GROWTH | CARCINOMA | EXPRESSION | Up-Regulation | Humans | Gene Expression Regulation, Neoplastic | Octamer Transcription Factor-3 - biosynthesis | Matrix Metalloproteinase 7 - biosynthesis | Lung Neoplasms - pathology | Matrix Metalloproteinase 1 - biosynthesis | Epithelial-Mesenchymal Transition - genetics | Cadherins - biosynthesis | beta Catenin - biosynthesis | Cell Hypoxia | RNA, Messenger - biosynthesis | Nuclear Proteins - biosynthesis | RNA Interference | Twist-Related Protein 1 - biosynthesis | Cadherins - genetics | Snail Family Transcription Factors | Matrix Metalloproteinase 2 - biosynthesis | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Matrix Metalloproteinase 9 - biosynthesis | Homeodomain Proteins - biosynthesis | Nanog Homeobox Protein | Vimentin - biosynthesis | Carcinoma, Non-Small-Cell Lung - genetics | Neoplasm Invasiveness | Repressor Proteins - genetics | Transcription Factors - biosynthesis | Cell Line, Tumor | Zinc Fingers - genetics | RNA, Small Interfering | Zinc Finger E-box-Binding Homeobox 1 | Care and treatment | Stem cells | Physiological aspects | Genetic aspects | Research | Lung cancer, Non-small cell | Risk factors | Studies | Proteins | Genotype & phenotype | Immunoglobulins | Laboratories | Plasmids | Lung cancer | Mortality | Hypoxia | Tumorigenesis | Metastasis | Index Medicus
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 03/2006, Volume 66, Issue 5, pp. 2725 - 2731
A critical event in the pathogenesis of invasive and metastatic cancer is E-cadherin loss of function. Renal clear cell carcinoma (RCC) is characterized by... 
BREAST-CANCER | INVASION | PROTEIN | FACTOR-1 | THERAPY | GENE | ONCOLOGY | TRANSCRIPTION FACTOR SNAIL | EPITHELIAL-MESENCHYMAL TRANSITIONS | HIF-ALPHA | EXPRESSION | Immunohistochemistry | RNA, Small Interfering - genetics | Kidney Neoplasms - genetics | Humans | Gene Expression Regulation, Neoplastic | Carcinoma, Renal Cell - genetics | Kidney Neoplasms - metabolism | Zinc Finger E-box Binding Homeobox 2 | Cadherins - biosynthesis | Hypoxia-Inducible Factor 1 - genetics | Repressor Proteins - physiology | RNA, Messenger - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Transcription, Genetic | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Cadherins - genetics | Hypoxia-Inducible Factor 1 - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - physiology | Transcription Factors - physiology | Basic Helix-Loop-Helix Transcription Factors - genetics | Homeodomain Proteins - biosynthesis | Carcinoma, Renal Cell - pathology | Down-Regulation | Hypoxia-Inducible Factor 1 - physiology | RNA, Messenger - genetics | Von Hippel-Lindau Tumor Suppressor Protein - biosynthesis | Repressor Proteins - genetics | Von Hippel-Lindau Tumor Suppressor Protein - physiology | Epithelial Cells - pathology | Transcription Factors - biosynthesis | Transcription Factors - genetics | Homeodomain Proteins - genetics | Carcinoma, Renal Cell - metabolism | Repressor Proteins - biosynthesis | Biopsy | Cell Adhesion - physiology | Kidney Neoplasms - pathology | Homeodomain Proteins - physiology | Mesoderm - pathology | Zinc Finger E-box-Binding Homeobox 1 | Index Medicus
Journal Article
Journal of Endodontics, ISSN 0099-2399, 2012, Volume 38, Issue 7, pp. 899 - 906
Journal Article
Oncology Reports, ISSN 1021-335X, 07/2016, Volume 36, Issue 1, pp. 10 - 22
Long non-coding RNAs (lncRNAs) have been identified to be critical mediators in various tumors associated with cancer progression. Long non-coding RNA... 
cell cycle regulatory protein | prostate cancer | lncRNA-ATB | proliferation | prognosis | LncRNA-ATB | Prognosis | Proliferation | Cell cycle regulatory protein | Prostate cancer | MORTALITY | DIAGNOSIS | METASTASIS | BREAST-CANCER | HEPATOCELLULAR-CARCINOMA | ONCOLOGY | COLORECTAL-CANCER | RESISTANCE | EXPRESSION | PROGRESSION | RNA, Small Interfering - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Epithelial-Mesenchymal Transition - genetics | Cadherins - biosynthesis | Prostatic Neoplasms - therapy | Zinc Finger E-box-Binding Homeobox 1 - biosynthesis | Prostatic Neoplasms - genetics | RNA Interference | Oncogene Proteins - biosynthesis | Trans-Activators - biosynthesis | Proto-Oncogene Proteins c-akt - metabolism | Prostatic Neoplasms - pathology | Zonula Occludens-1 Protein - biosynthesis | Cell Proliferation - genetics | Vimentin - biosynthesis | Cyclin D1 - biosynthesis | RNA, Long Noncoding - genetics | Signal Transduction - genetics | Prostatic Neoplasms - mortality | Cyclin E - biosynthesis | Cell Line, Tumor | Neoplasm Invasiveness - genetics | Development and progression | Genetic aspects | Cellular signal transduction | Gene expression | Health aspects | Lymphatic system | Colorectal cancer | Metastasis | Medical diagnosis | Multivariate analysis | Medical screening | Patients | Cancer therapies | Studies | Liver cancer | Medical prognosis | Index Medicus
Journal Article
Cancer Science, ISSN 1347-9032, 03/2017, Volume 108, Issue 3, pp. 419 - 426
Journal Article
Tumor Biology, ISSN 1010-4283, 4/2016, Volume 37, Issue 4, pp. 5427 - 5435
Despite the screening program, breast cancer is the commonest cause of cancer death in women in the industrialized world. In this study, we investigate the... 
Epithelial to mesenchymal transition | Biomedicine | K-RAS | NF-kB | Sonic Hedgehog | Cancer Research | PTX3 | Breast cancer markers | SIGNALING PATHWAYS | STEM-CELLS | STATES | PANCREATIC-CANCER | PRINCIPLES | TRANSITION | THERAPY | ONCOLOGY | INFLAMMATION | NF-KAPPA-B | Prognosis |