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Nature (London), ISSN 0028-0836, 06/2015, Volume 522, Issue 7557, pp. 450 - 454
The anaphase-promoting complex (APC/C) is a multimeric RING E3 ubiquitin ligase that controls chromosome segregation and mitotic exit. Its regulation by... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Phosphorylation | Ubiquitin - ultrastructure | Cadherins - metabolism | Humans | Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Ubiquitin - metabolism | Cell Cycle Proteins - ultrastructure | Substrate Specificity | Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome - ultrastructure | Structure-Activity Relationship | Anaphase-Promoting Complex-Cyclosome - ultrastructure | Protein Subunits - metabolism | Ubiquitin-Conjugating Enzymes - chemistry | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | Cell Cycle Proteins - chemistry | Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Ubiquitination | Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | Cadherins - chemistry | Cytoskeletal Proteins - metabolism | Lysine - metabolism | Anaphase-Promoting Complex-Cyclosome - chemistry | Cadherins - ultrastructure | Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | Catalytic Domain | F-Box Proteins - metabolism | Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | F-Box Proteins - chemistry | Cell Cycle Proteins - metabolism | Ubiquitin - chemistry | Models, Molecular | Ubiquitin-Conjugating Enzymes - ultrastructure | Cytoskeletal Proteins - chemistry | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Cryoelectron Microscopy | F-Box Proteins - ultrastructure | Ubiquitin-Conjugating Enzymes - metabolism | Protein Binding | Protein Subunits - chemistry | Apc10 Subunit, Anaphase-Promoting Complex-Cyclosome - chemistry | Anaphase-Promoting Complex-Cyclosome - metabolism | Apc11 Subunit, Anaphase-Promoting Complex-Cyclosome - metabolism | Apc1 Subunit, Anaphase-Promoting Complex-Cyclosome - ultrastructure | Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome - ultrastructure | Ubiquitin | Physiological aspects | Structure | Ubiquitin-proteasome system | Ligases | Proteins | Peptides | Molecular structure | Cyclin-dependent kinases | Cell division | Kinases | Gene expression | Index Medicus
Journal Article
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2014, Volume 111, Issue 48, pp. 17104 - 17109
Metastasis portends a poor prognosis for cancer patients. Primary tumor cells disseminate through the bloodstream before the appearance of detectable... 
Vimentin | Epithelial cells | Blood cells | Cell lines | Stem cells | Fluorescence | Breast cancer | Blood | Tumors | Cancer | Diagnostic | Cancer metastasis | MRNA | Nanotechnology | NanoFlares | nanotechnology | mRNA | diagnostic | cancer metastasis | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Carbocyanines - chemistry | Cadherins - metabolism | Vimentin - metabolism | Humans | Neoplastic Cells, Circulating - metabolism | Carbocyanines - metabolism | Transplantation, Heterologous | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | DNA, Antisense - genetics | Breast Neoplasms - metabolism | Vimentin - genetics | Base Sequence | Biomarkers, Tumor - metabolism | Female | Cadherins - genetics | Gold - chemistry | Green Fluorescent Proteins - metabolism | Nanotechnology - methods | Metal Nanoparticles - chemistry | RNA, Messenger - genetics | Neoplastic Cells, Circulating - chemistry | DNA, Antisense - metabolism | Fibronectins - metabolism | Breast Neoplasms - genetics | Breast Neoplasms - blood | Cell Line, Tumor | Luminescent Proteins - genetics | Biomarkers, Tumor - genetics | Fibronectins - genetics | DNA, Antisense - chemistry | Microscopy, Fluorescence | Luminescent Proteins - metabolism | Health aspects | Identification and classification | Cancer cells | Flow cytometry | Metastasis | Ribonucleic acid--RNA | Risk assessment | Index Medicus | Biological Sciences
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Journal Article