X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (26432) 26432
Publication (5638) 5638
Newsletter (521) 521
Book Review (364) 364
Book Chapter (325) 325
Conference Proceeding (153) 153
Dissertation (17) 17
Book / eBook (15) 15
Magazine Article (9) 9
Reference (8) 8
Data Set (6) 6
Newspaper Article (5) 5
Streaming Video (4) 4
Web Resource (4) 4
Trade Publication Article (2) 2
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (22795) 22795
index medicus (13580) 13580
caenorhabditis-elegans (13198) 13198
humans (8375) 8375
caenorhabditis elegans (7830) 7830
cell biology (7684) 7684
biochemistry & molecular biology (7328) 7328
caenorhabditis elegans - genetics (7248) 7248
caenorhabditis elegans proteins - metabolism (6365) 6365
caenorhabditis elegans - metabolism (5826) 5826
c-elegans (5527) 5527
caenorhabditis elegans proteins - genetics (5350) 5350
molecular sequence data (4948) 4948
research (4572) 4572
proteins (4199) 4199
amino acid sequence (4169) 4169
mutation (3990) 3990
physiological aspects (3361) 3361
mice (3206) 3206
article (3183) 3183
genetics & heredity (3176) 3176
developmental biology (3106) 3106
gene expression (3083) 3083
c. elegans (3009) 3009
signal transduction (2975) 2975
genetic aspects (2955) 2955
analysis (2914) 2914
caenorhabditis elegans - physiology (2794) 2794
expression (2673) 2673
female (2544) 2544
rna interference (2520) 2520
multidisciplinary sciences (2510) 2510
genes (2508) 2508
nematodes (2477) 2477
research article (2447) 2447
protein (2353) 2353
genetics (2347) 2347
male (2283) 2283
base sequence (2276) 2276
drosophila (2235) 2235
biology (2164) 2164
gene (1976) 1976
sequence homology, amino acid (1973) 1973
gene-expression (1969) 1969
oxidative stress (1951) 1951
life-span (1926) 1926
longevity (1861) 1861
aging (1850) 1850
caenorhabditis elegans proteins (1823) 1823
models, biological (1819) 1819
animals, genetically modified (1810) 1810
protein binding (1790) 1790
phenotype (1730) 1730
gene expression regulation, developmental (1725) 1725
gene expression regulation (1720) 1720
caenorhabditis elegans - embryology (1707) 1707
caenorhabditis elegans - cytology (1676) 1676
neurosciences (1640) 1640
caenorhabditis elegans - growth & development (1621) 1621
neurons (1599) 1599
transcription factors - metabolism (1549) 1549
molecular biology (1540) 1540
identification (1505) 1505
cloning, molecular (1393) 1393
saccharomyces-cerevisiae (1390) 1390
apoptosis (1373) 1373
rna (1367) 1367
fungi (1358) 1358
cells (1349) 1349
rna, messenger - metabolism (1347) 1347
caenorhabditis elegans - drug effects (1302) 1302
sequence alignment (1255) 1255
cell line (1232) 1232
nematoda (1229) 1229
transcription factors - genetics (1219) 1219
nematode caenorhabditis-elegans (1217) 1217
phosphorylation (1217) 1217
protein structure, tertiary (1194) 1194
neurons - metabolism (1168) 1168
genomics (1163) 1163
phylogeny (1151) 1151
caenorhabditis elegans - enzymology (1138) 1138
metabolism (1137) 1137
life sciences (1117) 1117
membrane proteins - metabolism (1113) 1113
caenorhabditis elegans proteins - physiology (1047) 1047
medicine (1042) 1042
binding sites (1024) 1024
caenorhabditis elegans proteins - chemistry (1014) 1014
helminth proteins - genetics (994) 994
worms (979) 979
drosophila-melanogaster (978) 978
in-vivo (972) 972
genomes (969) 969
rna, messenger - genetics (965) 965
rats (957) 957
biochemistry (950) 950
helminth proteins - metabolism (941) 941
science (931) 931
micrornas - genetics (926) 926
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (26948) 26948
Japanese (33) 33
French (20) 20
Chinese (18) 18
Russian (12) 12
Polish (6) 6
German (4) 4
Spanish (3) 3
Finnish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Methods, ISSN 1046-2023, 02/2017, Volume 115, pp. 80 - 90
We present TrackMate, an open source Fiji plugin for the automated, semi-automated, and manual tracking of single-particles. It offers a versatile and modular... 
Phototoxicity | Open-source software | Image analysis | Single-particle tracking | Microscopy | Clathin-mediated endocytosis | SYSTEM | CLATHRIN-MEDIATED ENDOCYTOSIS | TPLATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | TRANSPORT | DYNAMICS | ARABIDOPSIS | CELL | EMBRYOGENESIS | Image Processing, Computer-Assisted - statistics & numerical data | Plant Cells - metabolism | Adaptor Proteins, Vesicular Transport - genetics | Cell Tracking - methods | Embryo, Nonmammalian - metabolism | Arabidopsis - ultrastructure | Clathrin - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Fibroblasts - ultrastructure | Cell Tracking - statistics & numerical data | Clathrin - metabolism | Arabidopsis - metabolism | Caenorhabditis elegans | Endocytosis | Algorithms | Animals | Light Signal Transduction | Single-Cell Analysis - statistics & numerical data | Single-Cell Analysis - methods | Embryo, Nonmammalian - ultrastructure | Plant Cells - ultrastructure | Gene Expression Regulation, Plant | Software | Fibroblasts - metabolism | Single-Cell Analysis/methods | Arabidopsis/metabolism | Embryo, Nonmammalian/ultrastructure | Cellular Biology | Life Sciences | Clathrin/genetics | Fibroblasts/metabolism | Cell Tracking/methods | Plant Cells/metabolism | Cell Tracking/statistics & numerical data | Arabidopsis/ultrastructure | Image Processing, Computer-Assisted/statistics & numerical data | Embryo, Nonmammalian/metabolism | Adaptor Proteins, Vesicular Transport/genetics | Clathrin/metabolism | Plant Cells/ultrastructure | Single-Cell Analysis/statistics & numerical data | Fibroblasts/ultrastructure | Adaptor Proteins, Vesicular Transport/metabolism
Journal Article
Cancer Cell, ISSN 1535-6108, 2011, Volume 19, Issue 1, pp. 17 - 30
and mutations occur frequently in gliomas and acute myeloid leukemia, leading to simultaneous loss and gain of activities in the production of α-ketoglutarate... 
BREAST-CANCER | TRANSCRIPTIONAL ACTIVITY | IDH2 MUTATIONS | ONCOLOGY | PROLYL HYDROXYLATION | INTEGRATED GENOMIC ANALYSIS | 2-OXOGLUTARATE OXYGENASES | ACUTE MYELOID-LEUKEMIA | HIF-ALPHA | HISTONE DEMETHYLATION | FAMILY | CELL BIOLOGY | Dioxygenases - metabolism | Histone Demethylases - antagonists & inhibitors | Gene Expression - genetics | Caenorhabditis elegans Proteins - chemistry | Humans | Ketoglutaric Acids - chemistry | Glioma - genetics | F-Box Proteins | Oxidoreductases, N-Demethylating - antagonists & inhibitors | Ketoglutaric Acids - pharmacology | Cytosine - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Glutarates - chemistry | Oxidoreductases, N-Demethylating - metabolism | DNA-Binding Proteins - antagonists & inhibitors | Glioma - enzymology | Endostatins - metabolism | Models, Molecular | Isocitrate Dehydrogenase - genetics | Histone Demethylases - metabolism | Dioxygenases - antagonists & inhibitors | Amino Acid Substitution - physiology | Procollagen-Proline Dioxygenase - genetics | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - pharmacology | Histones - metabolism | Jumonji Domain-Containing Histone Demethylases - metabolism | Caenorhabditis elegans - enzymology | Cytosine - analogs & derivatives | Gene Expression - drug effects | Caenorhabditis elegans Proteins - metabolism | Isocitrate Dehydrogenase - antagonists & inhibitors | Glioma - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Biocatalysis - drug effects | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | Jumonji Domain-Containing Histone Demethylases - chemistry | Procollagen-Proline Dioxygenase - antagonists & inhibitors | Ketoglutaric Acids - metabolism | Oxalates - pharmacology | Binding, Competitive | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Catalytic Domain | Proto-Oncogene Proteins - genetics | Hypoxia-Inducible Factor-Proline Dioxygenases | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Animals | 5-Methylcytosine - metabolism | Caenorhabditis elegans Proteins - antagonists & inhibitors | Glutarates - metabolism
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2016, Volume 11, Issue 1, p. e0148089
Cellular energy regulation relies on complex signaling pathways that respond to fuel availability and metabolic demands. Dysregulation of these networks is... 
LIFE-SPAN | PPAR-ALPHA | ENERGY | FATTY-ACID-COMPOSITION | GLUCOSE | MULTIDISCIPLINARY SCIENCES | RECEPTOR NHR-49 | GENE-EXPRESSION | C-ELEGANS | LACTIC-ACIDOSIS | DIETARY RESTRICTION | Humans | Caenorhabditis elegans Proteins - metabolism | Oxygen - metabolism | Protein Subunits - metabolism | Aminoimidazole Carboxamide - pharmacology | Ribonucleotides - pharmacology | Cell Respiration - drug effects | Transcription, Genetic | Energy Metabolism - genetics | Fatty Acids - metabolism | Protein-Serine-Threonine Kinases - metabolism | Protein Subunits - genetics | Caenorhabditis elegans - metabolism | Signal Transduction | Caenorhabditis elegans - genetics | Lactic Acid - metabolism | Metformin - pharmacology | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Mitochondria - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Longevity - genetics | Mitochondria - drug effects | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | Caenorhabditis elegans - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Oxygen Consumption - drug effects | Glucose - metabolism | Caenorhabditis elegans Proteins - genetics | Energy Metabolism - drug effects | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Cell metabolism | Caenorhabditis elegans | Genetic aspects | Research | Protein kinases | Oxidative stress | Energy metabolism | Regulators | Transcription factors | Phosphorylation | Transcription | Oxidative metabolism | Homeostasis | Lipids | Kinases | AMP-activated protein kinase | Protein turnover | Proteins | Mitochondria | Energy | Evolutionary conservation | Physiology | Catalysis | Worms | Enzymes | AMP | Oxygen consumption | Fluxes | Metabolism | Mammals | Gene expression | Fatty acids | Strain | Signaling | Nematodes | Glycolysis | Diabetes | Lactic acid | Metformin | Metabolic disorders
Journal Article
Genes and Development, ISSN 0890-9369, 02/2009, Volume 23, Issue 4, pp. 496 - 511
Rictor is a component of the target of rapamycin complex 2 (TORC2). While TORC2 has been implicated in insulin and other growth factor signaling pathways, the... 
AKT | Fat metabolism | C. Elegans | Life span | Insulin/IGF | NERVOUS-SYSTEM | C. elegans | AKT/PKB | life span | DEVELOPMENTAL BIOLOGY | AGE-1 PI3 KINASE | CELL BIOLOGY | INSULIN | RAPTOR | MTOR COMPLEX-2 | LONGEVITY | SIGNALING PATHWAY | insulin/IGF | GENETICS & HEREDITY | C-ELEGANS | fat metabolism | TRANSCRIPTION FACTOR | Caenorhabditis elegans Proteins - metabolism | Reproduction - physiology | Fixatives - metabolism | Intestines - metabolism | Adipose Tissue - metabolism | Caenorhabditis elegans - physiology | Immediate-Early Proteins - metabolism | Oxazines - metabolism | Oncogene Protein v-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Somatomedins - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Boron Compounds - metabolism | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - growth & development | Signal Transduction | Caenorhabditis elegans - genetics | Mutation - genetics | Feeding Behavior - physiology | Carrier Proteins - genetics | Adaptor Proteins, Signal Transducing | Insulin - metabolism | Animals | Carrier Proteins - metabolism | Diet | Caenorhabditis elegans Proteins - genetics | Longevity - physiology | Lipid Metabolism - physiology | Life spans (Biology) | Caenorhabditis elegans | Immune response | Physiological aspects | Genetic aspects | Rapamycin | Research | insulin | IGF | Research Paper
Journal Article
Journal Article
Journal Article
Science, ISSN 0036-8075, 1/2011, Volume 331, Issue 6016, pp. 456 - 461
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2016, Volume 63, Issue 5, pp. 781 - 795
Mutations in the human autophagy gene cause the multisystem disorder Vici syndrome. Here we demonstrated that EPG5 is a Rab7 effector that determines the... 
RAB effector | LC3 | autophagosome maturation | epg-5 | SNARE | MEMBRANE-FUSION | LYSOSOME FUSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MACHINERY | MECHANISMS | SYNTAXIN 17 | MATURATION | VESICLE | C. ELEGANS | HOPS COMPLEX | CELL BIOLOGY | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Humans | Cataract - pathology | Qb-SNARE Proteins - metabolism | R-SNARE Proteins - metabolism | Caenorhabditis elegans Proteins - metabolism | Qb-SNARE Proteins - genetics | rab GTP-Binding Proteins - genetics | Endosomes - metabolism | Lysosomes - metabolism | Qc-SNARE Proteins - metabolism | Agenesis of Corpus Callosum - genetics | Endosomes - ultrastructure | Qa-SNARE Proteins - genetics | Autophagy - genetics | Synaptosomal-Associated Protein 25 - genetics | rab GTP-Binding Proteins - metabolism | Agenesis of Corpus Callosum - metabolism | Amino Acid Sequence | Caenorhabditis elegans - metabolism | Membrane Fusion | Signal Transduction | Caenorhabditis elegans - genetics | R-SNARE Proteins - genetics | Gene Expression Regulation | Autophagosomes - metabolism | Cataract - metabolism | Agenesis of Corpus Callosum - pathology | Autophagosomes - ultrastructure | Lysosomes - ultrastructure | Proteins - genetics | Sequence Homology, Amino Acid | Sequence Alignment | Animals | Proteins - metabolism | Qa-SNARE Proteins - metabolism | Protein Binding | Qc-SNARE Proteins - genetics | Cataract - genetics | Synaptosomal-Associated Protein 25 - metabolism | HeLa Cells | Caenorhabditis elegans Proteins - genetics | Yuan (China)
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 507, Issue 7493, pp. 448 - 454
Human neurons are functional over an entire lifetime, yet the mechanisms that preserve function and protect against neurodegeneration during ageing are... 
LIFE-SPAN | CAENORHABDITIS-ELEGANS | PROTEIN | CHROMATIN | MULTIDISCIPLINARY SCIENCES | GENOME-WIDE ANALYSIS | NEURONS | MILD COGNITIVE IMPAIRMENT | SEL-12 PRESENILIN | REPRESSOR | C. ELEGANS | Neurons - pathology | Up-Regulation | Humans | Oxidative Stress - physiology | Caenorhabditis elegans Proteins - metabolism | Phagosomes | Neurons - cytology | Cognition | Autophagy | Neuroprotective Agents - metabolism | Alzheimer Disease - pathology | Brain - metabolism | DNA-Binding Proteins - metabolism | Frontotemporal Dementia - metabolism | Young Adult | Cell Nucleus - metabolism | Aging - genetics | Cell Death - genetics | Chromatin Immunoprecipitation | Repressor Proteins - deficiency | Aged, 80 and over | Neurons - metabolism | Repressor Proteins - metabolism | Wnt Signaling Pathway | Frontotemporal Dementia - pathology | Brain - cytology | Amyloid beta-Peptides - toxicity | Cognitive Dysfunction - metabolism | Down-Regulation | Gene Expression Regulation | Lewy Body Disease - pathology | Oxidative Stress - genetics | Repressor Proteins - genetics | Longevity | Aging - pathology | Lewy Body Disease - metabolism | Transcription Factors - metabolism | Amyloid beta-Peptides - antagonists & inhibitors | Animals | Alzheimer Disease - metabolism | Brain - pathology | Aged | Mice | Alzheimer Disease - genetics | Aging - metabolism | Oxidative stress | Control | Transcription factors | Neurons | Aging | Physiological aspects | Genetic aspects | Research | Alzheimer's disease | Studies | Pathology | Cognitive ability | Epigenetics | Kinases | Stress response | Gene expression | Alzheimers disease | Age | Apoptosis
Journal Article