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American Journal of Hematology, ISSN 0361-8609, 08/2014, Volume 89, Issue 8, pp. E121 - E124
Journal Article
Chemical Communications, ISSN 1359-7345, 2010, Volume 46, Issue 1, pp. 97 - 99
A strained aza-dibenzocyclooctyne was prepared via a high-yielding synthetic route. Copper-free, strain-promoted click reaction with azides showed excellent... 
FREE TRIAZOLE FORMATION | PROTEIN PEGYLATION | POLYMER | LIGATION | FREE CLICK CHEMISTRY | CHEMISTRY, MULTIDISCIPLINARY | PEPTIDE | STRATEGIES | TOOL | Calbindins | Copper - chemistry | Cycloparaffins - chemistry | Aza Compounds - chemistry | Polyethylene Glycols - chemistry | Kinetics | S100 Calcium Binding Protein G - chemistry | Index Medicus
Journal Article
Experimental Neurology, ISSN 0014-4886, 11/2016, Volume 285, Issue Pt A, pp. 41 - 50
Transient receptor potential melastatin 2 (TRPM2) is a thermosensitive, Ca -permeable cation channel. TRPM2 contributes to the pathogenesis of inflammatory... 
Inflammatory bowel disease | TRPM2 | Sensory nerve | Enteric nervous system | Visceral hypersensitivity | CA2+ INFLUX | NERVE-FIBERS | PRIMARY AFFERENT NEURONS | ROOT GANGLION NEURONS | ADP-RIBOSE | NEUROSCIENCES | NEUROPATHIC PAIN | EXPERIMENTAL COLITIS | HYDROGEN-PEROXIDE | PRIMARY SENSORY NEURONS | TRPV1 EXPRESSION | Fluorescein-5-isothiocyanate - pharmacokinetics | Evoked Potentials, Motor - physiology | Colitis - complications | Colon - innervation | Evoked Potentials, Motor - drug effects | Male | Ganglia, Spinal - cytology | Antigens, CD - metabolism | Dextrans - pharmacokinetics | Hypersensitivity - metabolism | Colitis - chemically induced | Receptors, Purinergic P2X - metabolism | Hypersensitivity - genetics | Electromyography | Gastrointestinal Tract - innervation | Disease Models, Animal | Calcium-Binding Proteins | Calbindin 2 - metabolism | Mice, Inbred C57BL | Stilbamidines - pharmacokinetics | Rats | Fluorescein-5-isothiocyanate - analogs & derivatives | Mice, Transgenic | Integrin alpha Chains - metabolism | Visceral Pain - metabolism | Rats, Sprague-Dawley | Gastrointestinal Tract - metabolism | Nerve Tissue Proteins - metabolism | Visceral Pain - genetics | Animals | Microfilament Proteins | TRPM Cation Channels - genetics | Substance P - metabolism | Mice | TRPM Cation Channels - metabolism | Trinitrobenzenesulfonic Acid - toxicity | Visceral Pain - etiology | Allergy | Gastrointestinal diseases | Analysis | Gastrointestinal system | Physiological aspects | Colitis | Allergic reaction | Index Medicus
Journal Article
Journal of Comparative Neurology, ISSN 0021-9967, 03/2016, Volume 524, Issue 4, pp. 783 - 806
Journal Article
Journal Article
The Lancet, ISSN 0140-6736, 10/2017, Volume 390, Issue 10104, pp. 1758 - 1768
Niemann-Pick disease, type C1 (NPC1) is a lysosomal storage disorder characterised by progressive neurodegeneration. In preclinical testing,... 
MIGLUSTAT THERAPY | STORAGE | MEDICINE, GENERAL & INTERNAL | HEPATOCELLULAR-CARCINOMA | CHOLESTEROL | BIOMARKER | CYCLODEXTRIN | CALBINDIN-D | PATIENT | BRAIN | CHILDREN | Injections, Spinal | Niemann-Pick Disease, Type C - drug therapy | 2-Hydroxypropyl-beta-cyclodextrin - adverse effects | Humans | Rare Diseases - drug therapy | Hearing Loss, High-Frequency - chemically induced | Child, Preschool | Niemann-Pick Disease, Type C - cerebrospinal fluid | Fatty Acid Binding Protein 3 - cerebrospinal fluid | Male | Biomarkers - blood | Hydroxycholesterols - cerebrospinal fluid | 2-Hydroxypropyl-beta-cyclodextrin - administration & dosage | Disease Progression | Dose-Response Relationship, Drug | Young Adult | Adolescent | Calbindins - cerebrospinal fluid | Female | Hydroxycholesterols - blood | Biomarkers - cerebrospinal fluid | Niemann-Pick Disease, Type C - blood | Child | Niemann-Pick disease | Medical research | Genetic disorders | Research & development--R&D | Clinical trials | Patients | Cholesterol | Studies | Cyclodextrin | Neurodegeneration | Biomarkers | Drug therapy | Drug dosages | Cerebellum | Slopes | Regulatory agencies | Animal models | Medical services | Childrens health | Hepatocellular carcinoma | Cognition | Cyclodextrins | Cerebrospinal fluid | Dosage | Proteins | Randomization | Npc1 protein | Bioindicators | Safety | Age | Health | FDA approval | Hearing loss | Domains | Hearing | Medical centres | Life span | Hearing aids | Mastoiditis | Ototoxicity | Index Medicus | Abridged Index Medicus
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 06/2014, Volume 35, Issue 6, pp. 1325 - 1333
The molecular basis of selective neuronal vulnerability in Alzheimer's disease (AD) remains poorly understood. Using basal forebrain cholinergic neurons... 
CaMKI | Calbindin-D | GAP43 | Proteolysis | Basal forebrain | Calpain | Cholinergic system
Journal Article
Biochimica et Biophysica Acta - General Subjects, ISSN 0304-4165, 08/2012, Volume 1820, Issue 8, pp. 1294 - 1303
Background: Cytosolic Ca buffers are members of the large family of Ca -binding proteins and are essential components of the Ca signaling toolkit implicated in... 
Calcium homeostasome | Calcium buffer | Calretinin | Parvalbumin | Calcium-binding protein | Calbindin-D28k
Journal Article
Journal Article