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Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, p. e0138833
Vascular calcification (VC) is common in chronic kidney disease (CKD) and contributes to cardiovascular mortality. The calcium-sensing receptor (CaSR) is... 
KIDNEY-DISEASE | CINACALCET HCL | MULTIDISCIPLINARY SCIENCES | VASCULAR CALCIFICATION | ENDOTHELIAL-CELLS | GROWTH-FACTOR 23 | HEMODIALYSIS-PATIENTS | SECONDARY HYPERPARATHYROIDISM | CARDIOVASCULAR-DISEASE | SMOOTH-MUSCLE-CELLS | VITAMIN-D STATUS | Chondrogenesis - drug effects | Extracellular Matrix Proteins - biosynthesis | Muscle, Smooth, Vascular - metabolism | Calcium - metabolism | Humans | Middle Aged | Stress, Mechanical | Male | Aorta - metabolism | Young Adult | Pulsatile Flow - physiology | Transfection | Vascular Calcification - physiopathology | Adult | Female | Osteoblasts - cytology | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Receptors, Calcium-Sensing - antagonists & inhibitors | Recombinant Fusion Proteins - biosynthesis | Receptors, Calcium-Sensing - physiology | Calcium - pharmacology | Phenethylamines - pharmacology | Phosphoproteins - biosynthesis | Extracellular Matrix Proteins - genetics | Osteogenesis - drug effects | Cells, Cultured | Vascular Calcification - prevention & control | Phosphoproteins - genetics | Muscle, Smooth, Vascular - cytology | Receptors, Calcium-Sensing - agonists | Gene Expression Regulation - drug effects | Core Binding Factor Alpha 1 Subunit - biosynthesis | Receptors, Calcium-Sensing - genetics | Aged | Propylamines - pharmacology | Aorta - cytology | Core Binding Factor Alpha 1 Subunit - genetics | Physiological aspects | Calcification | Chronic kidney failure | Health aspects | Calcification (ectopic) | Cell culture | Transformation | Nephrology | Calcium | Laboratories | Homeostasis | Calcium content | Smooth muscle | Kinases | Phosphatase | Experiments | Arteries | Genotype & phenotype | Biomedical materials | Publishing | Aorta | Biocompatibility | Physiology | Deposition | Explants | Muscles | Exposure | Metabolism | Gene expression | Hospitals | Overexpression | Mechanical stimuli | Cardiovascular diseases | Calcium (extracellular) | Calcium-sensing receptors | Apoptosis | Veins & arteries
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 32, Issue 32, pp. 8161 - 8171
... healing, cartilage/bone regeneration and the sustained release of drugs due to similar physical properties to natural tissue [1–6] . Numerous researchers... 
Advanced Basic Science | Dentistry | Bone tissue regeneration | Hydrogel | Hyaluronic acid | Photopolymerization | Simvastatin | NANOPARTICLES | CELLS | IN-VITRO | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | Cell Death - radiation effects | Methacrylates - chemistry | RNA, Messenger - metabolism | Simvastatin - pharmacology | Spectroscopy, Fourier Transform Infrared | Tissue Scaffolds - chemistry | Polymerization - drug effects | Light | Surface Properties - drug effects | Methacrylates - chemical synthesis | Rheology - radiation effects | Cell Death - drug effects | Surface Properties - radiation effects | Osteogenesis - genetics | Bone Regeneration - drug effects | Cell Line | Cell Survival - drug effects | Rabbits | Calcification, Physiologic - drug effects | Polymerization - radiation effects | Osteogenesis - drug effects | RNA, Messenger - genetics | Hyaluronic Acid - chemistry | Calcification, Physiologic - radiation effects | Osteogenesis - radiation effects | Reverse Transcriptase Polymerase Chain Reaction | Cell Survival - radiation effects | Animals | Fibroblasts - radiation effects | Fibroblasts - drug effects | Cell Proliferation - drug effects | Fibroblasts - cytology | Mice | Kinetics | Hydrogels - chemistry | Rheology - drug effects | Cell Proliferation - radiation effects | Biological products | Antilipemic agents | Biomedical engineering
Journal Article
Developmental biology, ISSN 0012-1606, 2012, Volume 369, Issue 1, pp. 101 - 114
Embryonic development is controlled by a small set of signal transduction pathways, with vastly different phenotypic outcomes depending on the time and place... 
Development | Calvarial mesenchyme | Mouse model | Ror2 | Hair follicles | Wnt5a | PLANAR CELL POLARITY | CONVERGENT EXTENSION | DEVELOPMENTAL BIOLOGY | BETA | XENOPUS | PATHWAY | GENE-EXPRESSION | BONE | PROTEINS | RECEPTOR TYROSINE KINASE | Embryo, Mammalian - drug effects | Meninges - embryology | Skin - metabolism | Wnt-5a Protein | Wnt Proteins - metabolism | Embryo, Mammalian - metabolism | Bone and Bones - drug effects | Intercellular Signaling Peptides and Proteins - metabolism | Wnt Proteins - genetics | Female | Models, Animal | Hair Follicle - embryology | Repressor Proteins - metabolism | Skin - embryology | Calcification, Physiologic - genetics | Calcification, Physiologic - drug effects | Receptor Tyrosine Kinase-like Orphan Receptors - metabolism | Osteogenesis - drug effects | Tetracycline - pharmacology | Embryonic Development - genetics | Gene Expression Regulation, Developmental - drug effects | Mice, Transgenic | Meninges - drug effects | beta Catenin - metabolism | Hair Follicle - drug effects | Pregnancy | Hair Follicle - cytology | Phenotype | Animals | Wnt Signaling Pathway - drug effects | Wnt Signaling Pathway - genetics | Receptor Tyrosine Kinase-like Orphan Receptors - genetics | Mice | Bone and Bones - abnormalities | Bone and Bones - embryology | Embryonic Development - drug effects | Skin - drug effects | development | hair follicles | calvarial mesenchyme | mouse model
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e56451
Osterix (Osx/SP7) is a C2H2 zinc finger-containing transcription factor of the SP gene family. Osx knockout mice indicate that the gene plays an essential role... 
BONE-FORMATION | PATHWAY | UBIQUITIN | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | DEGRADATION | PROTEASOME SYSTEM | INHIBITORS | Cell Line | Bone and Bones - physiology | Mutagenesis, Site-Directed | Transcription Factors - chemistry | Calcification, Physiologic - drug effects | Proteasome Inhibitors - pharmacology | Humans | RNA, Messenger - genetics | Alkaline Phosphatase - metabolism | Transcription Factors - genetics | RNA, Messenger - metabolism | Gene Expression Regulation - drug effects | Transcription Factors - metabolism | Proteolysis - drug effects | Ubiquitination - drug effects | Cell Differentiation - drug effects | Bone and Bones - metabolism | Genetic Markers - genetics | Sp7 Transcription Factor | Mutation | Osteoblasts - cytology | Protein Stability | Binding Sites | Ubiquitin | Phosphatases | Luciferase | Genetic aspects | Genetic transcription | DNA binding proteins | Cells | Alkaline phosphatase | Collagen (type I) | Transcription factors | Immunoprecipitation | Laboratories | Handbooks | Biochemistry | Construction sites | Assaying | Mammalian cells | Proteins | Signal transduction | Bone growth | Ubiquitination | Lactacystin | Cell cycle | Post-translation | Biocompatibility | Zinc finger proteins | Localization | Deoxyribonucleic acid--DNA | Enzymes | Osteocalcin | Stability | Proteasome inhibitors | Zinc | Cycloheximide | Osteoblastogenesis | Lysine | Plasmids | Proteasomes | Differentiation | Binding sites | Osteogenesis | Deoxyribonucleic acid | DNA
Journal Article
PloS one, ISSN 1932-6203, 2015, Volume 10, Issue 8, p. e0133596
Journal Article
Biomaterials, ISSN 0142-9612, 2012, Volume 33, Issue 9, pp. 2629 - 2641
...). The effects on bone mesenchymal stem cell (MSC) osteogenic differentiation are studied systematically by various microscopic and biological characterization techniques... 
Advanced Basic Science | Dentistry | Osteogenic differentiation | Hierarchical topography | Cell spread | Mesenchymal stem cells | Titania nanotubes | RECRUITMENT | ACTIVATION | MATERIALS SCIENCE, BIOMATERIALS | TIO2 NANOTUBES | ENGINEERING, BIOMEDICAL | IMPLANTS | FATE | ADHESION | GROWTH | GENE-EXPRESSION | DYNAMICS | SURFACES | Mesenchymal Stromal Cells - enzymology | Titanium - pharmacology | Bone Marrow Cells - enzymology | Cell Count | Alkaline Phosphatase - metabolism | Titanium - chemistry | Extracellular Matrix - metabolism | Sincalide - metabolism | Nanotubes - chemistry | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Mesenchymal Stromal Cells - ultrastructure | Bone Marrow Cells - drug effects | Osteogenesis - genetics | Nanotubes - ultrastructure | Mesenchymal Stromal Cells - drug effects | Calcification, Physiologic - drug effects | Bone Marrow Cells - cytology | Extracellular Matrix - drug effects | Osteogenesis - drug effects | Rats | Cell Adhesion - drug effects | Collagen - secretion | Rats, Sprague-Dawley | Bone Marrow Cells - ultrastructure | Cell Shape - drug effects | Gene Expression Regulation - drug effects | Animals | Cell Differentiation - drug effects | Staining and Labeling | Cell Proliferation - drug effects | Cell Cycle - drug effects | Biological products | Phosphatases | Analysis | Collagen | Genes | Stem cells | Fluorescence | Gene expression | Orthodontics
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2012, Volume 7, Issue 2, p. e31650
CHARGE syndrome is caused by mutations in the CHD7 gene. Several organ systems including the retina, cranial nerves, inner ear and heart are affected in CHARGE... 
INNER-EAR | GENE | RETINAL LAMINATION | MULTIDISCIPLINARY SCIENCES | CRANIAL NERVE ABNORMALITIES | MUTATIONS | NEURAL CREST | EXPRESSION | ASSOCIATION | PHENOTYPIC SPECTRUM | N-CADHERIN | Body Patterning - drug effects | Retina - drug effects | Neovascularization, Physiologic - drug effects | Face - innervation | Heart - embryology | Retina - embryology | Spine - drug effects | RNA, Messenger - metabolism | Zebrafish - embryology | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Otolithic Membrane - embryology | Motor Neurons - cytology | Spine - embryology | Cell Polarity - drug effects | Otolithic Membrane - drug effects | DNA Helicases - genetics | Skull - drug effects | Motor Neurons - drug effects | Disease Models, Animal | Calcification, Physiologic - drug effects | Zebrafish Proteins - metabolism | Morpholinos - administration & dosage | RNA, Messenger - genetics | Embryonic Development - genetics | Gene Expression Regulation, Developmental - drug effects | Axons - drug effects | DNA-Binding Proteins - genetics | Zebrafish - genetics | Neural Crest - drug effects | Skull - embryology | DNA Helicases - metabolism | Injections | Animals | CHARGE Syndrome - metabolism | Neural Crest - embryology | Zebrafish - metabolism | Morpholinos - pharmacology | Retina - abnormalities | Heart - drug effects | CHARGE Syndrome - genetics | Zebrafish Proteins - genetics | Embryonic Development - drug effects | Body Patterning - genetics | Somites - drug effects | Embryonic development | Genetic aspects | Heart | Segmentation | Pathogenesis | Genomics | Retina | Hybridization | Inner ear | Defects | Charge simulation | Morphogenesis | Organismal biology | Reduction | Mineralization | Nerves | Polarity | Fish | Vagus nerve | Chromosomes | Motor neurons | Vertebrae | Neurons | Retinal cells | Zebrafish | RNA polymerase | Dentistry | Gene expression | Clustering | Retinal ganglion cells | Hospitals | Cranial nerves | CHARGE syndrome | Photoreceptors | Skull | Mutation | Aberration | Curvature | Binding sites
Journal Article
Journal Article