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Transplantation, ISSN 0041-1337, 2018, Volume 102, Issue 2S Suppl 1, pp. S60 - S70
.... The mammalian target of rapamycin (mTOR) inhibitors, sirolimus and everolimus, are increasingly used after organ transplantation with potential advantages in virus-associated posttransplant malignancies as well as anti-cancer properties... 
SOLID-ORGAN TRANSPLANTATION | SURGERY | RENAL-ALLOGRAFT RECIPIENTS | IMMUNOLOGY | TRANSPLANTATION | PHASE-II TRIAL | TUBEROUS SCLEROSIS COMPLEX | NONMELANOMA SKIN-CANCER | KAPOSIS-SARCOMA | POSTTRANSPLANT LYMPHOPROLIFERATIVE DISORDERS | KIDNEY-TRANSPLANTATION | SQUAMOUS-CELL CARCINOMA | ENDOTHELIAL GROWTH-FACTOR | TOR Serine-Threonine Kinases - metabolism | Tumor Virus Infections - virology | Humans | Immunosuppressive Agents - therapeutic use | Neoplasms - prevention & control | Protein Kinase Inhibitors - adverse effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Neoplasms - virology | Time Factors | Graft Rejection - mortality | Tumor Virus Infections - immunology | Anticarcinogenic Agents - adverse effects | Opportunistic Infections - immunology | Drug Therapy, Combination | Anticarcinogenic Agents - therapeutic use | Organ Transplantation - mortality | Graft Rejection - enzymology | Opportunistic Infections - virology | Graft Rejection - prevention & control | Risk Factors | Neoplasms - mortality | Treatment Outcome | Calcineurin Inhibitors - adverse effects | Animals | Signal Transduction - drug effects | Neoplasms - immunology | Protein Kinase Inhibitors - therapeutic use | Organ Transplantation - adverse effects | Immunosuppressive Agents - adverse effects | Graft Rejection - immunology | Immunocompromised Host | Graft Survival - drug effects | Prevention | Transplantation of organs, tissues, etc | Physiological aspects | Enzyme inhibitors | Carcinogenesis | Patient outcomes | Index Medicus
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2007, Volume 357, Issue 25, pp. 2562 - 2575
... Inhibitors in Renal Transplantation Henrik Ekberg, M.D., Ph.D., Helio Tedesco-Silva, M.D., Alper Demirbas, M.D., Štefan Vítko, M.D., Björn Nashan, M.D., Ph.D., Alp... 
MULTICENTER TRIAL | MEDICINE, GENERAL & INTERNAL | CYCLOSPORINE MICROEMULSION | EFFICACY | KIDNEY-TRANSPLANTATION | IMMUNOSUPPRESSION | ALLOGRAFT RECIPIENTS | TACROLIMUS | MYCOPHENOLATE-MOFETIL | SIROLIMUS | NEPHROTOXICITY | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Enzyme Inhibitors - administration & dosage | Antibodies, Monoclonal, Humanized | Calcineurin Inhibitors | Treatment Failure | Adult | Diabetes Mellitus - etiology | Female | Drug Therapy, Combination | Mycophenolic Acid - administration & dosage | Immunosuppressive Agents - administration & dosage | Sirolimus - adverse effects | Tacrolimus - administration & dosage | Prednisone - administration & dosage | Glomerular Filtration Rate | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Kidney Transplantation | Immunoglobulin G - administration & dosage | Opportunistic Infections | Sirolimus - administration & dosage | Mycophenolic Acid - analogs & derivatives | Antibodies, Monoclonal - administration & dosage | Cyclosporine - administration & dosage | Immunosuppressive Agents - adverse effects | Aged | Adrenal Cortex Hormones - administration & dosage | Transplantation | Corticosteroids | Kidneys | Research | Health aspects | Immunosuppressive agents | Medical research | Immunology | Inhibitor drugs | Transplants & implants | Toxicity | Inhibidors enzimàtics | Posologia | Ús terapèutic | Corticosteroides | Rebuig (Biologia) | Posology | Therapeutic use | Immunosupressive agents | Graft rejection | Trasplantament renal | Enzyme inhibitors | Adrenocortical hormones | Immunosupressors | Kidney transplantation | Tacrolimus: administration & dosage | Medical and Health Sciences | Graft Rejection: prevention & control | Immunoglobulin G: administration & dosage | Medicin och hälsovetenskap | Mycophenolic Acid: administration & dosage | Antibodies | Klinisk medicin | Monoclonal: administration & dosage | Prednisone: administration & dosage | Adrenal Cortex Hormones: administration & dosage | Immunosuppressive Agents: administration & dosage | Mycophenolic Acid: analogs & derivatives | Sirolimus: administration & dosage | Cyclosporine: administration & dosage | Calcineurin: antagonists & inhibitors | Diabetes Mellitus: etiology | Urologi och njurmedicin | Sirolimus: adverse effects | Adrenal Cortex Hormones: therapeutic use | Enzyme Inhibitors: administration & dosage | Immunosuppressive Agents: adverse effects | Clinical Medicine | Immunosuppressive Agents: therapeutic use | Urology and Nephrology
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 08/2009, Volume 9, Issue 8, pp. 1936 - 1945
This randomized, pilot study compared the Janus kinase inhibitor CP-690,550 (15 mg BID [CP15] and 30 mg BID [CP30], n = 20 each) with tacrolimus (n = 21) in de novo kidney allograft recipients... 
kidney | immunosuppression | transplant | inhibitor | Janus kinase (JAK) | CP-690,550 | CP‐690,550 | Immunosuppression | Inhibitor | Kidney | Transplant | NONHUMAN-PRIMATES | SURGERY | RENAL-TRANSPLANTATION | TRANSPLANTATION | 550 | REJECTION | CP-690 | MYCOPHENOLATE-MOFETIL | SIROLIMUS | Kidney Transplantation - pathology | Follow-Up Studies | Kidney - pathology | Humans | Immunosuppressive Agents - therapeutic use | Middle Aged | Male | Adrenal Cortex Hormones - therapeutic use | Glomerular Filtration Rate - physiology | Transplantation, Homologous | Dose-Response Relationship, Drug | Young Adult | Calcineurin Inhibitors | Kidney Transplantation - physiology | Piperidines | Pyrroles - adverse effects | Adult | Female | Drug Therapy, Combination | Pyrroles - therapeutic use | Kidney - physiopathology | Graft Rejection - prevention & control | Kaplan-Meier Estimate | Tacrolimus - adverse effects | Janus Kinases - antagonists & inhibitors | Adrenal Cortex Hormones - adverse effects | Mycophenolic Acid - adverse effects | Tacrolimus - therapeutic use | Pilot Projects | Mycophenolic Acid - analogs & derivatives | Mycophenolic Acid - therapeutic use | Biopsy | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Immunosuppressive Agents - adverse effects | Aged | Graft Rejection - immunology | Kidney Transplantation - immunology | Virus diseases | Medical colleges | Kidneys | Tacrolimus | Anemia | Immunotherapy | Transplantation | Kidney diseases | Health aspects | Index Medicus
Journal Article
American Journal of Transplantation, ISSN 1600-6135, 05/2014, Volume 14, Issue 5, pp. 1142 - 1151
Journal Article
by Su, L and Yin, L and Yang, JK and Sun, L
MEDICINE, ISSN 0025-7974, 06/2019, Volume 98, Issue 26, p. e16113
Journal Article
Clinical journal of the American Society of Nephrology, ISSN 1555-9041, 2017, Volume 12, Issue 8, pp. 1321 - 1336
... target of rapamycin inhibitor (mTOR) based regimen compared with a calcineurin inhibitor based regimen... 
CALCINEURIN-INHIBITOR | EARLY CONVERSION | EVEROLIMUS | EFFICACY | KIDNEY-TRANSPLANTATION | UROLOGY & NEPHROLOGY | MAINTENANCE IMMUNOSUPPRESSION | NEPHROPATHY | MYCOPHENOLATE-MOFETIL | SIROLIMUS | CYCLOSPORINE | Polyomavirus Infections - immunology | Tumor Virus Infections - virology | Cytomegalovirus Infections - epidemiology | Humans | Middle Aged | Tumor Virus Infections - diagnosis | Male | Cytomegalovirus Infections - immunology | BK Virus - pathogenicity | Protein Kinase Inhibitors - adverse effects | Incidence | TOR Serine-Threonine Kinases - antagonists & inhibitors | Time Factors | Tumor Virus Infections - immunology | Cytomegalovirus Infections - virology | Adult | Female | Opportunistic Infections - immunology | Drug Therapy, Combination | Odds Ratio | Tumor Virus Infections - epidemiology | Immunosuppressive Agents - administration & dosage | Opportunistic Infections - virology | Opportunistic Infections - epidemiology | Risk Assessment | Calcineurin Inhibitors - administration & dosage | Risk Factors | Polyomavirus Infections - epidemiology | Treatment Outcome | Chi-Square Distribution | Cytomegalovirus Infections - diagnosis | BK Virus - immunology | Opportunistic Infections - diagnosis | Randomized Controlled Trials as Topic | Polyomavirus Infections - diagnosis | Calcineurin Inhibitors - adverse effects | Protein Kinase Inhibitors - administration & dosage | Polyomavirus Infections - virology | Immunosuppressive Agents - adverse effects | Kidney Transplantation - adverse effects | cyclosporine | Confidence Intervals | Calcineurin inhibitor | glomerular filtration rate | tacrolimus | Calcineurin | proteinuria | kidney transplantation | Polyomavirus | Assessment | Cytomegalovirus Infections | immunosuppression | Risk | BK virus | Wound Healing | Meta-analysis | Calcineurin Inhibitors | everolimus | cytomegalovirus | sirolimus | Original
Journal Article
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