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Journal Article
Transplantation, ISSN 0041-1337, 11/2017, Volume 101, Issue 11, pp. 2780 - 2788
Journal Article
Journal Article
British Journal of Clinical Pharmacology, ISSN 0306-5251, 09/2015, Volume 80, Issue 3, pp. 548 - 559
Journal Article
Therapeutic Drug Monitoring, ISSN 0163-4356, 2016, Volume 38, Issue 2, pp. 143 - 169
Journal Article
Journal Article
Pharmacogenomics Journal, ISSN 1470-269X, 01/2017, Volume 17, Issue 1, pp. 61 - 68
Tacrolimus is dependent on CYP3A5 enzyme for metabolism. Expression of the CYP3A5 enzyme is controlled by several alleles including CYP3A5*1, CYP3A5*3,... 
BLOOD-CONCENTRATIONS | CYP3A5 GENOTYPE | GENETIC POLYMORPHISMS | POPULATION PHARMACOKINETICS | GENETICS & HEREDITY | PHARMACOLOGY & PHARMACY | CALCINEURIN INHIBITORS | DOSE REQUIREMENTS | CLINICAL PHARMACOKINETICS | DOSAGE REQUIREMENTS | SINGLE NUCLEOTIDE POLYMORPHISMS | P-GLYCOPROTEIN | United States - epidemiology | Calcineurin Inhibitors - pharmacokinetics | Humans | Immunosuppressive Agents - pharmacokinetics | Middle Aged | Male | Transplant Recipients | Young Adult | Drug Dosage Calculations | Canada - epidemiology | Cytochrome P-450 CYP3A - genetics | Pharmacogenomic Variants | Adult | Female | Immunosuppressive Agents - administration & dosage | Tacrolimus - administration & dosage | Pharmacogenetics | Calcineurin Inhibitors - administration & dosage | Gene Frequency | Graft Rejection - prevention & control | African Americans - genetics | Genotype | Treatment Outcome | Pharmacogenomic Testing | Tacrolimus - pharmacokinetics | Tacrolimus - adverse effects | Calcineurin Inhibitors - adverse effects | Phenotype | Metabolic Clearance Rate - genetics | Cytochrome P-450 CYP3A - metabolism | Graft Rejection - ethnology | Adolescent | Immunosuppressive Agents - adverse effects | Aged | Models, Genetic | Graft Rejection - immunology | Graft Survival - drug effects | Kidney Transplantation - adverse effects | Kidneys | Tacrolimus | Cytochrome P-450 | African Americans | Genetic aspects | Dosage and administration | Transplantation | Gene expression | Health aspects | Index Medicus | kidney transplant | pharmacokinetics | personalization | pharmacogenomics | tacrolimus
Journal Article
Clinical Transplantation, ISSN 0902-0063, 04/2015, Volume 29, Issue 4, pp. 294 - 300
Journal Article
Journal Article
Transplantation, ISSN 0041-1337, 08/2016, Volume 100, Issue 8, pp. 1705 - 1713
Journal Article