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Journal of Bone and Mineral Research, ISSN 0884-0431, 10/2017, Volume 32, Issue 10, pp. 2049 - 2061
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2009, Volume 206, Issue 1, pp. 249 - 258
Psoriasis is a type I interferon-driven T cell-mediated disease characterized by the recruitment of plasmacytoid dendritic cells (pDC) into the skin. The... 
PATHOGENESIS | MIGRATION | MEDICINE, RESEARCH & EXPERIMENTAL | DERMATITIS | INFLAMMATION | LYMPH-NODES | IN-VIVO | CYTOKINE | IMMUNOLOGY | PRECURSORS | T-CELLS | PROTEASES | CD8-Positive T-Lymphocytes - cytology | Neutrophils - cytology | Membrane Glycoproteins - metabolism | Skin - metabolism | Humans - metabolism | Antigens, CD - metabolism | Chemotaxis, Leukocyte - physiology | Lectins, C-Type - metabolism | Chemotaxis, Leukocyte - drug effects | Psoriasis - pathology | Psoriasis - metabolism | CD8-Positive T-Lymphocytes - metabolism | Receptors, Chemokine - genetics | Neutrophils - metabolism | Antibodies, Monoclonal - immunology | Fibroblasts - metabolism | Tretinoin - pharmacology | Antibodies, Monoclonal - pharmacology | Neutrophils - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Chemokines - genetics | Blotting, Western | Intercellular Adhesion Molecule-1 - metabolism | Calcitriol - pharmacology | Fibroblasts - drug effects | Chemokines - metabolism | Fibroblasts - cytology | Receptors, Immunologic - genetics | Chemokine CXCL10 - metabolism | Dermatitis, Atopic - genetics | Gene Expression - drug effects | Culture Media, Conditioned - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Lectins, C-Type - genetics | Psoriasis - genetics | Adult | Dendritic Cells - metabolism | Skin - pathology | Intercellular Signaling Peptides and Proteins | Receptors, Chemokine - metabolism | Cells, Cultured | Dermatitis, Atopic - pathology | Receptors, Chemokine - immunology | Membrane Glycoproteins - genetics | Chemokine CXCL10 - genetics | CD8-Positive T-Lymphocytes - drug effects | Dendritic Cells - cytology | Dermatitis, Atopic - metabolism | Receptors, Immunologic - metabolism
Journal Article
Archives of Biochemistry and Biophysics, ISSN 0003-9861, 2005, Volume 433, Issue 2, pp. 397 - 412
Drugs and bile acids are taken up into hepatocytes by specialized transport proteins localized at the basolateral membrane, e.g., organic anion transporting... 
Coactivators and corepressors | Gene regulation | Drug metabolism | Xenobiotics | Nuclear receptors | Bile acids and salts | Hepatocyte nuclear factors | SMALL HETERODIMER PARTNER | xenobiotics | NEGATIVE FEEDBACK-REGULATION | SALT EXPORT PUMP | BIOCHEMISTRY & MOLECULAR BIOLOGY | VITAMIN-D-RECEPTOR | hepatocyte nuclear factors | coactivators and corepressors | ORPHAN NUCLEAR RECEPTOR | nuclear receptors | BIOPHYSICS | gene regulation | CONSTITUTIVE ANDROSTANE RECEPTOR | drug metabolism | bile acids and salts | FARNESOID-X-RECEPTOR | CHOLESTEROL 7-ALPHA-HYDROXYLASE GENE | STEROL 27-HYDROXYLASE GENE | FAMILIAL INTRAHEPATIC CHOLESTASIS | Steroid 12-alpha-Hydroxylase - metabolism | Steroid Hydroxylases - metabolism | Histone Acetyltransferases | Receptors, Steroid - metabolism | Receptors, Virus - metabolism | Humans | Cytochrome P-450 Enzyme System - metabolism | Homeostasis | Receptors, Glucocorticoid - metabolism | Coxsackie and Adenovirus Receptor-Like Membrane Protein | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Transcription, Genetic | Heat-Shock Proteins - metabolism | Bile Acids and Salts - metabolism | Receptors, Calcitriol - metabolism | Forecasting | Transcription Factors - metabolism | Feedback, Physiological | Pharmaceutical Preparations - metabolism | Animals | Cholesterol 7-alpha-Hydroxylase - metabolism | Models, Biological | Nuclear Receptor Coactivator 1 | Ligands | Trans-Activators - metabolism | Cholestanetriol 26-Monooxygenase | Hepatocyte Nuclear Factor 4 | Multidrug Resistance-Associated Proteins - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 11/2016, Volume 436, Issue C, pp. 224 - 239
Fibroblast growth factor-23 (FGF23) is a bone-derived hormone, suppressing renal phosphate reabsorption and vitamin D hormone synthesis in proximal tubules,... 
Fibroblast growth factor-23 | Bone | Vitamin D | Parathyroid hormone | Secondary hyperparathyroidism | D METABOLISM | VITAMIN-D-RECEPTOR | DEFICIENT MICE | CELL BIOLOGY | GLUCOSE-HOMEOSTASIS | HYPOPHOSPHATEMIC RICKETS | IN-VIVO | ENDOCRINOLOGY & METABOLISM | GROWTH-FACTOR 23 | GENE-EXPRESSION | RENAL PHOSPHATE-TRANSPORT | TRANSGENIC MICE | Calcium Channels - metabolism | Glucuronidase - metabolism | Parathyroid Hormone - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Glucuronidase - deficiency | Bone and Bones - drug effects | Fibroblast Growth Factors - metabolism | Hyperparathyroidism - metabolism | TRPV Cation Channels - metabolism | Kidney - metabolism | Parathyroid Hormone - metabolism | Bone and Bones - metabolism | Cell Membrane - metabolism | Kidney Tubules - metabolism | Cell Membrane - drug effects | Cyclic AMP - blood | Kidney - drug effects | Kidney Tubules - drug effects | Mice, Inbred C57BL | Osteoblasts - drug effects | RNA, Messenger - genetics | Receptors, Calcitriol - metabolism | Recombinant Proteins - pharmacology | Animals | Signal Transduction - drug effects | Models, Biological | Osteoblasts - metabolism | Lactose | Analysis | Physiological aspects | Calcifediol | Bones | Cyclic adenylic acid | Fibroblast growth factors | Alfacalcidol | Density
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 11/2004, Volume 19, Issue 11, pp. 1873 - 1881
We determined that sFRP‐1 mRNA was differentially expressed by osteoblast/stromal cell lines and that sFRP‐1 neutralizing antibodies and siRNA complementary to... 
secreted Frizzled‐related protein | RANKL | osteoclast | Wnt | Secreted Frizzled-related protein | Osteoclast | BONE-DENSITY | secreted frizzled-related protein | COLONY-STIMULATING FACTOR | MOUSE | DIFFERENTIATION FACTOR | RECEPTOR | OSTEOPROTEGERIN | CELL-LINES | ENDOCRINOLOGY & METABOLISM | LIGAND | CHONDROGENESIS | SPEMANN ORGANIZER | Receptor Activator of Nuclear Factor-kappa B | Membrane Glycoproteins - metabolism | Male | RANK Ligand | Gene Expression Profiling | Wnt Proteins | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | Intercellular Signaling Peptides and Proteins - physiology | Dose-Response Relationship, Drug | Intercellular Signaling Peptides and Proteins - metabolism | In Situ Hybridization | Membrane Glycoproteins - antagonists & inhibitors | Membrane Proteins - physiology | Parathyroid Hormone - metabolism | Bone and Bones - metabolism | Escherichia coli - metabolism | Polymerase Chain Reaction | Calcitriol - metabolism | Membrane Proteins - metabolism | Interleukin-6 - metabolism | Chondrocytes - metabolism | Recombinant Proteins - metabolism | Cell Line | Enzyme-Linked Immunosorbent Assay | Signal Transduction | Mice, Inbred C57BL | Carrier Proteins - antagonists & inhibitors | Gene Expression Regulation | Glutathione Transferase - metabolism | Recombinant Proteins - chemistry | Interleukin-11 - metabolism | Macrophage Colony-Stimulating Factor - metabolism | Osteoclasts - metabolism | Animals | Carrier Proteins - metabolism | Mice | Osteoblasts - metabolism | Bone Marrow Cells - metabolism | RNA, Small Interfering - metabolism
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 06/2009, Volume 23, Issue 6, pp. 1643 - 1654
Late-onset Alzheimer's disease is often connected with nutritional misbalance, such as enhanced cholesterol intake, deficiency in polyunsaturated fatty acids,... 
Shedding | Vitamin A | Nuclear receptors | Alzheimer's disease | Amyloid precursor protein | vitamin A | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYLOID-PRECURSOR-PROTEIN | shedding | X-RECEPTOR | BETA-PEPTIDE | NEUROBLASTOMA-CELLS | HIPPOCAMPAL-NEURONS | VITAMIN-A | CELL BIOLOGY | nuclear receptors | RESPONSE ELEMENT | amyloid precursor protein | BIOLOGY | LONG-TERM POTENTIATION | EXPRESSION | Amyloid Precursor Protein Secretases - genetics | Up-Regulation | Tretinoin - chemistry | Humans | Male | PPAR gamma - metabolism | Receptors, Calcitriol - genetics | Receptors, Retinoic Acid - genetics | DNA-Binding Proteins - metabolism | Keratolytic Agents - metabolism | Receptors, Thyroid Hormone - genetics | Tretinoin - metabolism | Liver X Receptors | Acitretin - metabolism | Amyloid beta-Protein Precursor - metabolism | Membrane Proteins - metabolism | Molecular Structure | Orphan Nuclear Receptors | Retinoid X Receptors - genetics | Retinoid X Receptors - metabolism | PPAR gamma - genetics | Cell Line | Promoter Regions, Genetic | Membrane Proteins - genetics | Gene Expression Regulation | ADAM10 Protein | Mice, Transgenic | Receptors, Retinoic Acid - metabolism | Receptors, Cytoplasmic and Nuclear - genetics | Receptors, Calcitriol - metabolism | DNA-Binding Proteins - genetics | Acitretin - chemistry | Receptors, Thyroid Hormone - metabolism | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Alzheimer Disease - metabolism | Mice | ADAM Proteins - genetics | Receptors, Cytoplasmic and Nuclear - metabolism
Journal Article
Hepatology, ISSN 0270-9139, 12/2012, Volume 56, Issue 6, pp. 2288 - 2296
Nuclear receptors (NRs) play crucial roles in the regulation of hepatic cholesterol synthesis, metabolism, and conversion to bile acids, but their actions in... 
NPC1L1 | PATHWAY | CELLULAR CHOLESTEROL | MACROPHAGES | GENE-EXPRESSION | ALPHA | MICE | ABSORPTION | SECRETION | GASTROENTEROLOGY & HEPATOLOGY | MODULATION | RNA-Binding Proteins - genetics | Steroid Hydroxylases - metabolism | Receptors, Estrogen - metabolism | Receptors, Steroid - metabolism | Bile Ducts - metabolism | Gene Expression Profiling | Hepatocytes - metabolism | Orphan Nuclear Receptors - metabolism | PPAR gamma - metabolism | Receptors, Calcitriol - genetics | Bile Ducts - cytology | Receptors, Thyroid Hormone - genetics | Liver X Receptors | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | ATP-Binding Cassette Transporters - metabolism | Membrane Transport Proteins - metabolism | ATP Binding Cassette Transporter 1 | Retinoid X Receptors - genetics | Retinoid X Receptors - metabolism | Steroid Hydroxylases - genetics | PPAR delta - genetics | PPAR gamma - genetics | Hepatocyte Nuclear Factor 4 - metabolism | Receptors, Estrogen - genetics | Cells, Cultured | Rats | Hepatocyte Nuclear Factor 4 - genetics | Receptors, Calcitriol - metabolism | Transcription Factors - genetics | Cholesterol - metabolism | Orphan Nuclear Receptors - genetics | Receptors, Thyroid Hormone - metabolism | Transcription Factors - metabolism | Animals | Receptors, Steroid - genetics | PPAR delta - metabolism | Homeostasis - genetics | RNA-Binding Proteins - metabolism
Journal Article
Journal Article
Journal Article