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Current Medicinal Chemistry, ISSN 0929-8673, 04/2013, Volume 20, Issue 10, pp. 1241 - 1285
Ion channel targeted drugs have always been related with either the central nervous system (CNS), the peripheral nervous system, or the cardiovascular system.... 
ASIC | TRP | Central nervous system | P2X | KCNQ | NMDA | CNS | Ion channels | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | GATED SODIUM-CHANNELS | SUBTYPE-SELECTIVE AGONIST | D-ASPARTATE RECEPTOR | ion channels | ACID-SENSING ION-CHANNEL-1 | central nervous system | GLYCINE ANTAGONIST GV150526 | TARANTULA TOXIN PSALMOTOXIN-1 | TRAUMATIC BRAIN-INJURY | ISCHEMIC CELL-DEATH | PHARMACOLOGY & PHARMACY | PERIPHERAL NEUROPATHIC PAIN | TRANSGENIC MOUSE MODEL | Ligand-Gated Ion Channels - antagonists & inhibitors | Transient Receptor Potential Channels - antagonists & inhibitors | Calcium Channels - metabolism | Humans | Calcium Channel Blockers - therapeutic use | Potassium Channel Blockers - therapeutic use | Sodium Channel Blockers - pharmacology | Calcium Channel Blockers - pharmacology | Ion Channels - antagonists & inhibitors | Potassium Channels - metabolism | Animals | Ion Channels - metabolism | Sodium Channels - chemistry | Calcium Channels - chemistry | Central Nervous System Diseases - drug therapy | Sodium Channels - metabolism | Calcium Channel Blockers - chemistry | Sodium Channel Blockers - therapeutic use | Potassium Channels - chemistry | Sodium Channel Blockers - chemistry | Transient Receptor Potential Channels - metabolism | Ligand-Gated Ion Channels - metabolism | Potassium Channel Blockers - chemistry | Potassium Channel Blockers - pharmacology
Journal Article
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2017, Volume 60, Issue 23, pp. 9769 - 9789
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 2006, Volume 14, Issue 24, pp. 8582 - 8589
4-Aryl-3,4-dihydropyrimidin-2(1 )-thiones were synthesized by Lewis acid-catalyzed Biginelli condensation (Methods B and C). Dihydropyrimidin-2-thiones were... 
Ferric chloride | Boric acid | Dihydropyrimidin-2-thiones (DHPM-2-thiones) | Biginelli reaction | Calcium channel blocker activity | boric acid | ANTIHYPERTENSIVE AGENTS | CHEMISTRY, MEDICINAL | BIGINELLI DIHYDROPYRIMIDINE SYNTHESIS | SOLVENT-FREE CONDITIONS | ONE-POT SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | CHROMATOGRAPHIC RESOLUTION | calcium channel blocker activity | ADRENOCEPTOR-SELECTIVE ANTAGONISTS | IMPROVED PROTOCOL CONDITIONS | CONDENSATION REACTION | ferric chloride | dihydropyrimidin-2-thiones (DHPM-2-thiones) | ACID-ESTERS | PHARMACOLOGICAL-PROPERTIES | Calcium Channel Blockers - chemical synthesis | Dihydropyridines - chemistry | Vasodilator Agents - pharmacology | Chlorides - pharmacology | Thiones - chemistry | Rats | Male | Thiones - chemical synthesis | Calcium Channel Blockers - pharmacology | Parasympatholytics - pharmacology | Barium Compounds - pharmacology | Dihydropyridines - chemical synthesis | Ileum - drug effects | Animals | Calcium Channels - chemistry | Potassium Chloride - pharmacology | Calcium Channel Blockers - chemistry | Dihydropyridines - pharmacology | Vasodilator Agents - chemical synthesis | Female | Vasodilator Agents - chemistry | Aorta, Thoracic - drug effects | Thiones - pharmacology | Iron salts | Universities and colleges | Condensation | Calcium channel blockers
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 2/2008, Volume 51, Issue 3, pp. 347 - 372
Journal Article
Journal Article