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Nature Genetics, ISSN 1061-4036, 02/2014, Volume 46, Issue 2, pp. 188 - 193
Mitochondrial Ca2+ uptake has key roles in cell life and death. Physiological Ca2+ signaling regulates aerobic metabolism, whereas pathological Ca2+ overload... 
UNIPORTER | DISEASE | GENETICS & HEREDITY | MUSCULAR-DYSTROPHY | CA2+ UPTAKE | CELL-SURVIVAL | PROTEINS | MCU | Immunohistochemistry | Calcium Channels - metabolism | Calcium Signaling - physiology | Humans | DNA, Complementary - genetics | Molecular Sequence Data | Mitochondrial Membrane Transport Proteins - genetics | Histological Techniques | Cation Transport Proteins - metabolism | Base Sequence | Membrane Potential, Mitochondrial - genetics | Cation Transport Proteins - genetics | Quadriceps Muscle - pathology | Real-Time Polymerase Chain Reaction | Calcium-Binding Proteins - metabolism | Mitochondrial Membrane Transport Proteins - metabolism | Mitochondria - metabolism | Sequence Analysis, DNA | Exome - genetics | Phenotype | Analysis of Variance | Pedigree | Extrapyramidal Tracts - pathology | Fluorescent Antibody Technique | Polymorphism, Single Nucleotide - genetics | Learning Disorders - genetics | Movement Disorders - genetics | Muscular Diseases - genetics | Calcium Signaling - genetics | Calcium-Binding Proteins - genetics | Gene mutations | Cellular signal transduction | Muscle diseases | Genetic aspects | Research | Health aspects | Risk factors | Proteins | Medical research | Cell culture | Mitochondria | Genealogy | Biomedical research | Nuclear magnetic resonance--NMR | Mutation | Kinases | Muscular dystrophy | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2014, Volume 111, Issue 17, pp. 6497 - 6502
Journal Article
Developmental Cell, ISSN 1534-5807, 2002, Volume 3, Issue 6, pp. 889 - 901
Signaling by RANKL is essential for terminal differentiation of monocytes/mcrophages into osteoclasts. The TRAF6 and c-Fos signaling pathways both play... 
LYMPH-NODE ORGANOGENESIS | CELLS | CYCLOSPORINE-A | OSTEOPROTEGERIN-LIGAND | KEY REGULATOR | C-FOS | RECEPTOR ACTIVATOR | GENE-EXPRESSION | DEVELOPMENTAL BIOLOGY | OSTEOPETROSIS | NF-KAPPA-B | CELL BIOLOGY | Transcription, Genetic - drug effects | Genetic Testing | Membrane Glycoproteins - metabolism | Oligonucleotide Array Sequence Analysis | RANK Ligand | Osteoclasts - cytology | Promoter Regions, Genetic - drug effects | RNA, Messenger - metabolism | Calcineurin - genetics | Cell Culture Techniques | Active Transport, Cell Nucleus - genetics | Signal Transduction - genetics | Nuclear Proteins | Signal Transduction - drug effects | Calcium Signaling - drug effects | Active Transport, Cell Nucleus - drug effects | Hematopoietic Stem Cells - cytology | Proto-Oncogene Proteins c-fos - genetics | Mice | Transcription, Genetic - genetics | Calcium Signaling - genetics | Receptor Activator of Nuclear Factor-kappa B | Transcription Factors - deficiency | Promoter Regions, Genetic - genetics | DNA-Binding Proteins - deficiency | Cell Differentiation - genetics | Carrier Proteins - pharmacology | Hematopoietic Stem Cells - drug effects | Gene Expression Regulation - genetics | Membrane Glycoproteins - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Proto-Oncogene Proteins c-fos - metabolism | Hematopoietic Stem Cells - metabolism | NFATC Transcription Factors | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Osteoclasts - metabolism | Membrane Glycoproteins - genetics | Gene Expression Regulation - drug effects | Proteins - genetics | Carrier Proteins - genetics | TNF Receptor-Associated Factor 6 | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Cell Differentiation - drug effects | Calcineurin - metabolism | Osteoclasts - drug effects | Index Medicus
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 03/2016, Volume 76, Issue 6, pp. 1494 - 1505
Journal Article
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 12/2017, Volume 23, Issue 12, pp. 1454 - 1454
Uncoupling protein 1 (UCP1) plays a central role in nonshivering thermogenesis in brown fat; however, its role in beige fat remains unclear. Here we report a... 
MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT HYPERTHERMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BROWN ADIPOSE-TISSUE | ENDOPLASMIC-RETICULUM STRESS | RYANODINE RECEPTOR GENE | RELEASE CHANNEL | MASS-SPECTROMETRY | ADAPTIVE NONSHIVERING THERMOGENESIS | CELL BIOLOGY | ENERGY-EXPENDITURE | UNCOUPLING PROTEIN-1 | FK506-BINDING PROTEIN FKBP12.6 | Animals, Newborn | Thermogenesis - genetics | Uncoupling Protein 1 - genetics | Calcium - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Signal Transduction - genetics | Mice, Knockout | Sarcoplasmic Reticulum Calcium-Transporting ATPases - physiology | Animals | Swine | HEK293 Cells | Glucose - metabolism | Mice | Calcium Signaling - genetics | Adipose Tissue, Beige - metabolism | Homeostasis - genetics | Uncoupling Protein 1 - physiology | Physiological aspects | Homeostasis | Brown adipose tissue | Genetic aspects | Research | Calcium ions | Cycles | Calcium | Body weight | Ryanodine receptors | Pyruvic acid | Body weight loss | Glucose | Adipocytes | Ca2+-transporting ATPase | Calcium signalling | Receptors | Uncoupling protein 1 | Rodents | Calcium homeostasis | Metabolism | Glucose tolerance | Energy balance | Thermogenesis | Glycolysis | Adrenergic receptors | Endoplasmic reticulum | ATP | Receptors (physiology) | Adenosine triphosphatase | Calcium (reticular) | Index Medicus | Calcium cycling | SERCA2 | Non-canonical thermogenesis | Obesity | Beige fat | UCP1 | Diabetes
Journal Article
by Arking, Dan E and Pulit, Sara L and Crotti, Lia and van der Harst, Pim and Munroe, Patricia B and Koopmann, Tamara T and Sotoodehnia, Nona and Rossin, Elizabeth J and Morley, Michael and Wang, Xinchen and Johnson, Anew D and Lundby, Alicia and Gudbjartsson, Daníel F and Noseworthy, Peter A and Eijgelsheim, Mark and Bradford, Yuki and Tarasov, Kirill V and Dörr, Marcus and Müller-Nurasyid, Martina and Lahtinen, Annukka M and Nolte, Ilja M and Smith, Albert Vernon and Bis, Joshua C and Isaacs, Aaron and Newhouse, Stephen J and Evans, Daniel S and Post, Wendy S and Waggott, Daryl and Lyytikäinen, Leo-Pekka and Hicks, Anew A and Eisele, Lewin and Ellinghaus, David and Hayward, Caroline and Navarro, Pau and Ulivi, Sheila and Tanaka, Toshiko and Tester, David J and Chatel, Stéphanie and Gustafsson, Stefan and Kumari, Meena and Morris, Richard W and Naluai, Åsa T and Padmanabhan, Sandosh and Kluttig, Alexander and Strohmer, Bernhard and Panayiotou, Anie G and Torres, Maria and Knoflach, Michael and Hubacek, Jaroslav A and Slowikowski, Kamil and Raychaudhuri, Soumya and Kumar, Runjun D and Harris, Tamara B and Launer, Lenore J and Shuldiner, Alan R and Alonso, Alvaro and Bader, Joel S and Ehret, Georg and Huang, Hailiang and Kao, W. H. Linda and Strait, James B and Macfarlane, Peter W and Brown, Morris and Caulfield, Mark J and Samani, Nilesh J and Kronenberg, Florian and Willeit, Johann and Smith, J. Gustav and Greiser, Karin H and Meyer zu Schwabedissen, Henriette and Werdan, Karl and Carella, Massimo and Zelante, Leopoldo and Heckbert, Susan R and Psaty, Bruce M and Rotter, Jerome I and Kolcic, Ivana and Polašek, Ozren and Wright, Alan F and Griffin, Maura and Daly, Mark J and Arnar, David O and Hólm, Hilma and Thorsteinsdottir, Unnur and Denny, Joshua C and Roden, Dan M and Zuvich, Rebecca L and Emilsson, Valur and Plump, Anew S and Larson, Martin G and O'Donnell, Christopher J and Yin, Xiaoyan and Bobbo, Marco and D'Adamo, Adamo P and Iorio, Annamaria and Sinagra, Gianfranco and Carracedo, Angel and Cummings, Steven R and Nalls, Michael A and Jula, Antti and ... and DCCT EDIC and COGENT Consortium and eMERGE Consortium and CARe Consortium and HRGEN Consortium and DCCT/EDIC and Högskolan Dalarna and Akademin Utbildning, hälsa och samhälle and Medicinsk vetenskap
Nature genetics, ISSN 1061-4036, 2014, Volume 46, Issue 8, pp. 826 - 836
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 11/2015, Volume 125, Issue 11, pp. 4091 - 4106
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2014, Volume 111, Issue 11, pp. 4197 - 4202
Signaling through the store-operated Ca2+ release-activated Ca2+ (CRAC) channel regulates critical cellular functions, including gene expression, cell growth... 
Muscular diseases | HEK293 cells | Calcium | Lymphocytes | Alleles | Miosis | Platelets | Genetic mutation | Embryos | Bleeding | Calcium signaling | Human genetics | human genetics | ZEBRAFISH | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | calcium signaling | MAST-CELLS | CRAC CHANNELS | CA2+ STORE DEPLETION | STROMAL INTERACTION MOLECULE-1 | CALCIUM | ENDOPLASMIC-RETICULUM | PROTEINS | PLASMA MEMBRANE JUNCTIONS | Humans | Molecular Sequence Data | Myopathies, Structural, Congenital - genetics | DNA Primers - genetics | Erythrocytes, Abnormal | Miosis - genetics | Base Sequence | Ichthyosis - genetics | Female | Neoplasm Proteins - genetics | Calcium Channels - genetics | Child | Blood Platelet Disorders - genetics | Stromal Interaction Molecule 1 | Mutagenesis, Site-Directed | Membrane Proteins - genetics | Zebrafish | Spleen - abnormalities | Mutation - genetics | Dyslexia - genetics | ORAI1 Protein | Sequence Analysis, DNA | Patch-Clamp Techniques | Animals | Migraine Disorders - genetics | Pedigree | Muscle Fatigue - genetics | Calcium Signaling - genetics | Calcium channels | Genetic disorders | Gene mutations | Physiological aspects | Genetic research | Genetic aspects | Research | Health aspects | Cytoplasm | Proteins | Signal transduction | Cell growth | Homeostasis | Mutation | Gene expression | Index Medicus | Biological Sciences
Journal Article