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1. Full Text Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic amp-protein kinase a and inflammasome-dependent IL-1 signaling
by Larena, Maximilian and Holmgren, Jan and Lebens, Michael and Terrinoni, Manuela and Lundgren, Anna and Sahlgrenska akademin and Institute of Biomedicine, Department of Microbiology and Immunology and Göteborgs universitet and Gothenburg University and Institutionen för biomedicin, avdelningen för mikrobiologi och immunologi and Sahlgrenska Academy
The Journal of immunology (1950), ISSN 0022-1767, 04/2015, Volume 194, Issue 8, pp. 3829 - 3839
Life Sciences & Biomedicine | Immunology | Science & Technology | CARD Signaling Adaptor Proteins - immunology | Apoptosis Regulatory Proteins - immunology | Adjuvants, Immunologic - pharmacology | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Middle Aged | Interleukin-1beta - immunology | Male | Caspase 1 - immunology | Enzyme Activation - drug effects | Enzyme Activation - immunology | Signal Transduction - immunology | Signal Transduction - drug effects | Calcium-Binding Proteins - immunology | Cyclic AMP-Dependent Protein Kinases - immunology | Cyclic AMP - immunology | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - immunology | Th17 Cells - immunology | Adult | Female | Th17 Cells - cytology | Cholera Toxin - pharmacology | Carrier Proteins - immunology | Index Medicus | Abridged Index Medicus | Calcium-Binding Proteins/immunology | Signal Transducing/immunology | Apoptosis Regulatory Proteins/immunology | Cyclic AMP/ immunology | Enzyme Activation/drug effects/immunology | Adjuvants | Immunologi inom det medicinska området | Interleukin-1beta/ immunology | Adaptor Proteins | Th17 Cells/cytology/ immunology | Signal Transduction/ drug effects/immunology | Caspase 1/immunology | Carrier Proteins/immunology | Cholera Toxin/ pharmacology | Cyclic AMP-Dependent Protein Kinases/ immunology | CARD Signaling Adaptor Proteins/immunology | Immunologic/ pharmacology | Immunology in the medical area | Inflammasomes/ immunology
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2. Full Text Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells
by Vaeth, Martin and Zee, Isabelle and Concepcion, Axel R and Maus, Mate and Shaw, Patrick and Portal-Celhay, Cynthia and Zahra, Aleena and Kozhaya, Lina and Weidinger, Carl and Philips, Jennifer and Unutmaz, Derya and Feske, Stefan
The Journal of immunology (1950), ISSN 0022-1767, 08/2015, Volume 195, Issue 3, pp. 1202 - 1217
Life Sciences & Biomedicine | Immunology | Science & Technology | Calcium Channels - metabolism | Membrane Glycoproteins - metabolism | Calcium - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Humans | Endoplasmic Reticulum - metabolism | Lymphocyte Activation - immunology | Calcium-Binding Proteins - immunology | Calcium Signaling - immunology | Calcium Channels - genetics | Carrier Proteins - immunology | Macrophages - immunology | Stromal Interaction Molecule 1 | Apoptosis Regulatory Proteins - immunology | Mice, Inbred C57BL | Phagocytosis - immunology | Stromal Interaction Molecule 2 | Antigen Presentation - genetics | Mice, Transgenic | Macrophages - cytology | Antigen Presentation - immunology | ORAI1 Protein | Cell Differentiation - immunology | Immunity, Innate - immunology | Severe Combined Immunodeficiency - genetics | Animals | Inflammasomes - immunology | T-Lymphocytes - immunology | Dendritic Cells - cytology | Mice | Index Medicus | Abridged Index Medicus | phagolysosome | phagocytosis | macrophages | calcium | dendritic cells | STIM1 | STIM2 | inflammasome | SOCE | NLRP3 | immunodeficiency | CRAC channel
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3. Full Text Differential Expression of Interleukin-17A and -17F Is Coupled to T Cell Receptor Signaling via Inducible T Cell Kinase
by Gomez-Rodriguez, Julio and Sahu, Nisebita and Handon, Robin and Davidson, Todd S and Anderson, Stacie M and Kirby, Martha R and August, Avery and Schwartzberg, Pamela L
Immunity (Cambridge, Mass.), ISSN 1074-7613, 10/2009, Volume 31, Issue 4, pp. 587 - 597
MOLIMMUNO | CELLIMMUNO | Life Sciences & Biomedicine | Immunology | Science & Technology | Calcium - metabolism | Protein-Tyrosine Kinases - metabolism | Calcium - immunology | Protein-Tyrosine Kinases - immunology | CD4-Positive T-Lymphocytes - immunology | Signal Transduction - immunology | Protein-Tyrosine Kinases - genetics | NFATC Transcription Factors - immunology | Receptors, Retinoic Acid - immunology | Receptors, Antigen, T-Cell - immunology | Receptors, Thyroid Hormone - immunology | Protein-Serine-Threonine Kinases - metabolism | Cytokines - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 | Lung - pathology | Phospholipase C gamma - metabolism | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Mice, Inbred C57BL | NFATC Transcription Factors - metabolism | CD4-Positive T-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - genetics | Receptors, Retinoic Acid - metabolism | Interleukin-17 - biosynthesis | Mice, Knockout | Receptors, Thyroid Hormone - metabolism | Phospholipase C gamma - immunology | Animals | Protein-Serine-Threonine Kinases - immunology | Mice | Promoter Regions, Genetic - immunology | Lung - immunology | Autoimmunity | Tyrosine | Chromatin | Bacterial infections | Interleukins | Genetic research | Phospholipases | T cells | Tretinoin | Transcription factors | Cytokines | Plasmids | Rodents | T cell receptors | Kinases | Immune system | Cell adhesion & migration | Index Medicus
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4. Full Text Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor–notch signaling cascade
by Xia, Mingcan, PhD and Viera-Hutchins, Loida, MD and Garcia-Lloret, Maria, MD and Noval Rivas, Magali, PhD and Wise, Petra, PhD and McGhee, Sean A., MD and Chatila, Zena K and Daher, Nancy, PhD and Sioutas, Constantinos, PhD and Chatila, Talal A., MD, MSc
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 441 - 453
Allergy and Immunology | airway hyperresponsiveness | Traffic-related particulate matter | diesel exhaust particles | ultrafine particles | Jagged 1 | Notch | asthma | allergic airway inflammation | aryl hydrocarbon receptor | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Allergens - adverse effects | Bronchial Hyperreactivity - immunology | Dendritic Cells - immunology | Humans | Dendritic Cells - pathology | Gene Expression Profiling | Monocytes - immunology | Bronchial Hyperreactivity - genetics | CD11c Antigen - immunology | Respiratory Hypersensitivity - pathology | CD11c Antigen - genetics | Immunoglobulin E - genetics | Calcium-Binding Proteins - immunology | Serrate-Jagged Proteins | T-Lymphocytes, Helper-Inducer - immunology | Monocytes - pathology | Vehicle Emissions | T-Lymphocytes, Helper-Inducer - pathology | Disease Models, Animal | Jagged-1 Protein | Bronchial Hyperreactivity - chemically induced | Signal Transduction | Membrane Proteins - genetics | Particulate Matter - adverse effects | Respiratory Hypersensitivity - chemically induced | Gene Expression Regulation | Intercellular Signaling Peptides and Proteins - genetics | Receptors, Aryl Hydrocarbon - genetics | Receptor, Notch1 - immunology | Membrane Proteins - immunology | Mice, Transgenic | Respiratory Hypersensitivity - immunology | Receptors, Cell Surface - immunology | Respiratory Hypersensitivity - genetics | Bronchial Hyperreactivity - pathology | Animals | Alleles | Mice | Primary Cell Culture | Receptor, Notch1 - genetics | Receptors, Aryl Hydrocarbon - immunology | Intercellular Signaling Peptides and Proteins - immunology | Calcium-Binding Proteins - genetics | Receptors, Cell Surface - genetics | Medical colleges | Air pollution | Asthma | Antigens | Aqueous solutions | Cytokines | Dendritic cells | Lymphocytes | Atherosclerosis | Traffic | Atoms & subatomic particles | Hydrocarbons | Inflammation | Pollutants | Index Medicus | Abridged Index Medicus
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5. Full Text Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states
by Furman, David and Chang, Junlei and Lartigue, Lydia and Bolen, Christopher R and Haddad, François and Gaudilliere, Brice and Ganio, Edward A and Fragiadakis, Gabriela K and Spitzer, Matthew H and Douchet, Isabelle and Daburon, Sophie and Moreau, Jean-François and Nolan, Garry P and Blanco, Patrick and Déchanet-Merville, Julie and Dekker, Cornelia L and Jojic, Vladimir and Kuo, Calvin J and Davis, Mark M and Faustin, Benjamin
Nature medicine, ISSN 1078-8956, 02/2017, Volume 23, Issue 2, pp. 174 - 184
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Toll-Like Receptor 5 - genetics | Humans | Middle Aged | Oxidative Stress - immunology | Transcriptome | Immunoblotting | Male | Purinergic P1 Receptor Antagonists - pharmacology | Young Adult | Toll-Like Receptor 8 - immunology | Aging - immunology | Toll-Like Receptor 6 - immunology | Aging - genetics | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Aged, 80 and over | Caffeine - pharmacology | Hypertension - genetics | Intracellular Signaling Peptides and Proteins - genetics | Interleukin 1 Receptor Antagonist Protein - immunology | Carotid Intima-Media Thickness | Mortality | Neutrophils - drug effects | Hypertension - immunology | Nucleotides - metabolism | Toll-Like Receptor 5 - immunology | Monocytes - drug effects | Regression Analysis | Phenotype | Mice | Calcium-Binding Proteins - genetics | Metabolomics | Pulse Wave Analysis | Neutrophil Activation - drug effects | Cytidine - pharmacology | Interleukin 1 Receptor Antagonist Protein - genetics | Intracellular Signaling Peptides and Proteins - immunology | Cytidine - analogs & derivatives | CARD Signaling Adaptor Proteins - genetics | Toll-Like Receptor 6 - genetics | Adult | Female | Blood Pressure - drug effects | Blood Platelets - drug effects | Macrophages - immunology | Cytokines - immunology | CARD Signaling Adaptor Proteins - immunology | Cell Line | Vascular Stiffness - genetics | Cytokines - metabolism | Oxidative Stress - genetics | Interleukin-1beta - immunology | Adenine - pharmacology | Inflammation - immunology | Inflammasomes - genetics | Vascular Stiffness - immunology | Animals | Inflammasomes - immunology | Toll-Like Receptor 8 - genetics | Inflammation - genetics | Aged | Platelet Activation - drug effects | Genetic aspects | Immune response | Gene expression | Health aspects | Aging | Inflammation | Immune system | Index Medicus
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6. Full Text Targeting of macrophage galactose‐type C‐type lectin (MGL) induces DC signaling and activation
by Napoletano, Chiara and Zizzari, Ilaria G and Rughetti, Aurelia and Rahimi, Hassan and Irimura, Tatsuro and Clausen, Henrik and Wandall, Hans H and Belleudi, Francesca and Bellati, Filippo and Pierelli, Luca and Frati, Luigi and Nuti, Marianna
European journal of immunology, ISSN 0014-2980, 04/2012, Volume 42, Issue 4, pp. 936 - 945
MUC1 | Dendritic cells | Macrophage galactose‐type C‐type lectin (MGL) | C‐type lectins | Tn‐tumor associated antigens | Macrophage galactose-type C-type lectin (MGL) | Tn-tumor associated antigens | C-type lectins | Life Sciences & Biomedicine | Immunology | Science & Technology | Acetylglucosamine - immunology | Calcium - metabolism | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | NF-kappa B - immunology | Calcium - immunology | NF-kappa B - metabolism | MAP Kinase Signaling System - immunology | Acetylglucosamine - metabolism | Lectins, C-Type - metabolism | CD8-Positive T-Lymphocytes - metabolism | Phosphorylation - immunology | Dendritic Cells - metabolism | Mitogen-Activated Protein Kinase 3 - immunology | Mitogen-Activated Protein Kinase 1 - immunology | Mucin-1 - metabolism | Antigens, Neoplasm - immunology | Cells, Cultured | Cancer Vaccines - immunology | Mitogen-Activated Protein Kinase 3 - metabolism | Up-Regulation - immunology | Mucin-1 - immunology | Dendritic Cells - cytology | CD8-Positive T-Lymphocytes - immunology | Lymphocyte Activation - physiology | Mitogen-Activated Protein Kinase 1 - metabolism | T cell receptors | Cancer | Index Medicus
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7. Full Text HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex that Regulates DNA-Mediated Innate Immune Response
by Morchikh, Mehdi and Cribier, Alexandra and Raffel, Raoul and Amraoui, Sonia and Cau, Julien and Severac, Dany and Dubois, Emeric and Schwartz, Olivier and Bennasser, Yamina and Benkirane, Monsef
Molecular cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
HEXIM1 | DNA-PK | innate immune response | herpesvirus | paraspeckles | cGAS | NEAT1 | interferon stimulatory DNA | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Octamer Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Herpesvirus 8, Human - immunology | RNA, Long Noncoding - immunology | PTB-Associated Splicing Factor - genetics | RNA Interference | Calcium-Binding Proteins - immunology | Octamer Transcription Factors - genetics | Nucleotidyltransferases - metabolism | Intracellular Signaling Peptides and Proteins - genetics | DNA-Binding Proteins | Signal Transduction | Membrane Proteins - genetics | RNA-Binding Proteins - immunology | PTB-Associated Splicing Factor - metabolism | Nuclear Matrix-Associated Proteins - metabolism | PTB-Associated Splicing Factor - immunology | DNA - metabolism | Host-Pathogen Interactions | Nuclear Matrix-Associated Proteins - genetics | Transcription Factors | HeLa Cells | RNA-Binding Proteins - metabolism | Calcium-Binding Proteins - genetics | RNA-Binding Proteins - genetics | Multiprotein Complexes | Human Umbilical Vein Endothelial Cells - immunology | Intracellular Signaling Peptides and Proteins - immunology | Human Umbilical Vein Endothelial Cells - virology | Interferon Regulatory Factor-3 - genetics | Ku Autoantigen - genetics | Transfection | HEK293 Cells | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Octamer Transcription Factors - metabolism | Interferon Regulatory Factor-3 - immunology | Calcium-Binding Proteins - metabolism | DNA - immunology | Nuclear Matrix-Associated Proteins - immunology | Ku Autoantigen - immunology | Membrane Proteins - immunology | Nuclear Proteins - metabolism | Ku Autoantigen - metabolism | RNA, Long Noncoding - genetics | Immunity, Innate | Nuclear Proteins - immunology | DNA - genetics | Interferon Regulatory Factor-3 - metabolism | Nucleotidyltransferases - genetics | Protein Binding | Nucleotidyltransferases - immunology | RNA, Long Noncoding - metabolism | RNA sequencing | Immune response | RNA | DNA | Genetic research | Interferon | Biological response modifiers | Mass spectrometry | Index Medicus | Human Umbilical Vein Endothelial Cells | Nuclear Matrix-Associated Proteins | Herpesvirus 8, Human | RNA-Binding Proteins | Life Sciences | Interferon Regulatory Factor-3 | Genetics | Calcium-Binding Proteins | Intracellular Signaling Peptides and Proteins | PTB-Associated Splicing Factor | Nuclear Proteins | Membrane Proteins | Nucleotidyltransferases | Ku Autoantigen | Octamer Transcription Factors | RNA, Long Noncoding
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8. Full Text The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways
by Hedl, Matija and Zheng, Shasha and Abraham, Clara
The Journal of immunology (1950), ISSN 0022-1767, 06/2014, Volume 192, Issue 12, pp. 5924 - 5932
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-18 - immunology | Receptors, Interleukin-1 Type I - immunology | Humans | Inflammatory Bowel Diseases - immunology | NF-kappa B - immunology | Male | Extracellular Signal-Regulated MAP Kinases - genetics | MAP Kinase Signaling System - immunology | Extracellular Signal-Regulated MAP Kinases - immunology | Phosphatidylinositol 3-Kinases - immunology | Chromosomes, Human, Pair 2 - genetics | Interleukin-18 Receptor beta Subunit - genetics | MAP Kinase Signaling System - genetics | Autocrine Communication - immunology | Inflammatory Bowel Diseases - genetics | Interleukin-18 Receptor alpha Subunit - genetics | Calcium Signaling - immunology | Female | Polymorphism, Single Nucleotide - immunology | Macrophages - immunology | Interleukin-18 Receptor alpha Subunit - immunology | Gene Expression Regulation - genetics | Gene Expression Regulation - immunology | Autocrine Communication - genetics | Phosphatidylinositol 3-Kinases - genetics | Interleukin-18 Receptor beta Subunit - immunology | Chromosomes, Human, Pair 2 - immunology | NF-kappa B - genetics | Receptors, Interleukin-1 Type I - genetics | Calcium Signaling - genetics | Interleukin-18 - genetics | Index Medicus | Abridged Index Medicus
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