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Nature, ISSN 0028-0836, 08/2012, Volume 488, Issue 7413, pp. 670 - 674
The inflammasome regulates the release of caspase activation-dependent cytokines, including interleukin (IL)-1 beta, IL-18 and high-mobility group box 1... 
PATHWAYS | APOPTOSIS | ACID | PROTEIN-KINASE PKR | MULTIDISCIPLINARY SCIENCES | INFECTION | NLRP3 INFLAMMASOME | ELF2-ALPHA | STRESS | BINDING | SUBSTRATE RECOGNITION | Crystallins - metabolism | Interleukin-6 - analysis | Phosphorylation | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | eIF-2 Kinase - metabolism | Humans | Salmonella Infections - immunology | Male | Salmonella Infections - metabolism | HMGB1 Protein - secretion | Interleukin-1beta - blood | eIF-2 Kinase - deficiency | Adenosine Triphosphate - pharmacology | CARD Signaling Adaptor Proteins - metabolism | Transfection | Interleukin-6 - blood | Rotenone - pharmacology | Female | Membrane Proteins - metabolism | Escherichia coli - physiology | Macrophages, Peritoneal - drug effects | eIF-2 Kinase - genetics | Calcium-Binding Proteins - metabolism | Cell Line | Salmonella typhimurium - physiology | Interleukin-18 - blood | Salmonella typhimurium - immunology | Inflammasomes - agonists | Mice, Inbred C57BL | Peritonitis - metabolism | Cells, Cultured | Escherichia coli - immunology | Antigens, Bacterial - pharmacology | Escherichia coli Infections - metabolism | eIF-2 Kinase - antagonists & inhibitors | Apoptosis Regulatory Proteins - metabolism | Animals | Carrier Proteins - metabolism | Bacterial Toxins - pharmacology | Uric Acid - pharmacology | RNA, Double-Stranded - immunology | RNA, Double-Stranded - pharmacology | Escherichia coli Infections - immunology | Mice | Adaptor Proteins, Signal Transducing - metabolism | Macrophages, Peritoneal - metabolism | HMGB1 Protein - blood | Physiological aspects | Chromosomal proteins | Research | Cytokines | Aluminum | Health aspects | Proteins | E coli | Pathogenesis | Plasmids | Bone marrow | Bacteria | Kinases | Index Medicus
Journal Article
Journal Article
Intensive Care Medicine, ISSN 0342-4642, 1/2010, Volume 36, Issue 1, pp. 107 - 115
Journal Article
Journal of Neurotrauma, ISSN 0897-7151, 04/2010, Volume 27, Issue 4, pp. 669 - 682
There is an urgent need for both the scientific development and clinical validation of novel therapies for acute spinal cord injury (SCI). The scientific... 
Traumatic spinal cord injury | Biomarkers | Clinical trial | Inflammation | Cerebrospinal fluid | clinical trial | FUNCTIONAL RECOVERY | RAT | biomarkers | LEVEL NEUROPATHIC PAIN | TISSUE-DAMAGE | NEUROSCIENCES | CLINICAL NEUROLOGY | traumatic spinal cord injury | TUMOR-NECROSIS-FACTOR | inflammation | GM-CSF | cerebrospinal fluid | CLINICAL-TRIALS | CONTUSION INJURY | ICCP PANEL | DECREASES SECONDARY DEGENERATION | CRITICAL CARE MEDICINE | Predictive Value of Tests | Prospective Studies | Cytokines - analysis | Humans | Middle Aged | Interleukin-8 - cerebrospinal fluid | Male | Young Adult | Chemokine CCL2 - cerebrospinal fluid | Inflammation Mediators - cerebrospinal fluid | Inflammation Mediators - analysis | Myelitis - immunology | Recovery of Function - physiology | Nerve Growth Factors - cerebrospinal fluid | Interleukin-6 - cerebrospinal fluid | S100 Calcium Binding Protein beta Subunit | Myelitis - physiopathology | Biomarkers - analysis | Biomarkers - blood | Myelitis - cerebrospinal fluid | Trauma Severity Indices | Chemokine CCL2 - blood | Cytokines - cerebrospinal fluid | S100 Proteins - analysis | tau Proteins - blood | Spinal Cord - immunology | Spinal Cord - physiopathology | Biomarkers - cerebrospinal fluid | Chemokine CCL2 - analysis | Interleukin-6 - analysis | Prognosis | Spinal Cord - metabolism | Glial Fibrillary Acidic Protein - cerebrospinal fluid | Interleukin-6 - blood | S100 Proteins - blood | Adult | Female | Nerve Growth Factors - blood | Interleukin-8 - blood | Cytokines - blood | Enzyme-Linked Immunosorbent Assay | Glial Fibrillary Acidic Protein - analysis | S100 Proteins - cerebrospinal fluid | tau Proteins - cerebrospinal fluid | Interleukin-8 - analysis | Nerve Growth Factors - analysis | Glial Fibrillary Acidic Protein - blood | Spinal Cord Injuries - physiopathology | tau Proteins - analysis | Spinal Cord Injuries - diagnosis | Spinal Cord Injuries - cerebrospinal fluid | Care and treatment | Patient outcomes | Physiological aspects | Spinal cord injuries | Diagnosis | Biological markers | Cerebrospinal fluid proteins | Body fluids | Cytokines | Index Medicus
Journal Article
Acta Neurochirurgica, ISSN 0001-6268, 1/2012, Volume 154, Issue 1, pp. 93 - 103
Journal Article
Thrombosis and Haemostasis, ISSN 0340-6245, 2010, Volume 104, Issue 4, pp. 811 - 822
Matrix γ-carboxyglutamate (Gla) protein (MGP) is an important local inhibitor of vascular calcification, which can undergo two post-translational... 
Cardiovascular Disease | matrix Gla protein | calcification | vitamin K | Gla-domain proteins | Cardiovascular Biology and Cell Signalling | Calcification | Cardiovascular disease | Matrix gla protein | Vitamin K | RHEUMATOID-ARTHRITIS | cardiovascular disease | BONE MORPHOGENETIC PROTEIN-2 | VASCULAR CALCIFICATION | MENAQUINONE INTAKE | GAMMA-CARBOXYGLUTAMIC ACID | CORONARY-ARTERY ATHEROSCLEROSIS | VITAMIN-K | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | STAGE RENAL-DISEASE | CARDIOVASCULAR RISK | Enzyme-Linked Immunosorbent Assay - methods | Prognosis | Extracellular Matrix Proteins - biosynthesis | Arthritis, Rheumatoid - blood | Humans | Middle Aged | Chondrocalcinosis - diagnosis | Feasibility Studies | Aortic Valve Insufficiency - blood | Adult | Vitamin K - administration & dosage | Chondrocalcinosis - physiopathology | Calcium-Binding Proteins - blood | Arthritis, Rheumatoid - diagnosis | Arthritis, Rheumatoid - physiopathology | Kidney Failure, Chronic - physiopathology | Calcium-Binding Proteins - biosynthesis | Kidney Failure, Chronic - diagnosis | Extracellular Matrix Proteins - genetics | Aortic Valve Insufficiency - physiopathology | Extracellular Matrix Proteins - blood | Biomarkers - blood | Disease Progression | Kidney Failure, Chronic - blood | Calcinosis | Vitamin K - blood | Aged | Protein Processing, Post-Translational | Antibodies, Monoclonal - metabolism | Chondrocalcinosis - blood | Aortic Valve Insufficiency - diagnosis | Calcium-Binding Proteins - genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, pp. e83397 - e83397
Nesfatin-1 is an anorexigenic peptide involved in energy homeostasis. Recently, nesfatin-1 was reported to decrease blood glucose level and improve insulin... 
ENERGY-BALANCE | RAT | GLUCOSE | MULTIDISCIPLINARY SCIENCES | RECEPTOR | SECRETION | MODEL | BLOOD-BRAIN-BARRIER | INSULIN SENSITIVITY | NUTRIENT | Nerve Tissue Proteins - blood | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Diet, High-Fat - adverse effects | Male | Muscle, Skeletal - metabolism | Diabetes Mellitus, Type 2 - metabolism | Gastric Mucosa - metabolism | Insulin - blood | DNA-Binding Proteins - metabolism | Diabetes Mellitus, Experimental - blood | Fatty Acids, Nonesterified - metabolism | DNA-Binding Proteins - administration & dosage | Diabetes Mellitus, Type 2 - etiology | Fatty Acids, Nonesterified - blood | Nerve Tissue Proteins - administration & dosage | Calcium-Binding Proteins - blood | Diabetes Mellitus, Experimental - metabolism | Calcium-Binding Proteins - metabolism | Oxidation-Reduction | Insulin Resistance | Calcium-Binding Proteins - administration & dosage | Nerve Tissue Proteins - metabolism | Diabetes Mellitus, Type 2 - blood | Animals | Diabetes Mellitus, Experimental - etiology | Hypothalamus - metabolism | Mice | Streptozocin - toxicity | DNA-Binding Proteins - blood | Enzyme Activation | Blood Glucose - metabolism | Acetyl-CoA Carboxylase - metabolism | Blood sugar | Body weight | Muscles | Insulin resistance | Comparative analysis | Fatty acids | Protein kinases | Insulin | Intravenous administration | Streptozocin | Homeostasis | Hypothalamus | Glucose | Kinases | AMP-activated protein kinase | Blood | Western blotting | High fat diet | Rodents | Oxidation | Lipid metabolism | AMP | Diabetes mellitus | Rats | Metabolism | Skeletal muscle | Energy balance | Food intake | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, pp. e56805 - e56805
The acknowledgement of risks for traumatic brain injury in American football players has prompted studies for sideline concussion diagnosis and testing for... 
AUTOANTIBODIES | IMPACT BIOMECHANICS | ALZHEIMERS-DISEASE | MULTIDISCIPLINARY SCIENCES | MINOR HEAD-INJURY | NEUROLOGICAL DISORDERS | SERUM S100-BETA | CONCUSSION | CHRONIC TRAUMATIC ENCEPHALOPATHY | COMPUTED-TOMOGRAPHY | PROFESSIONAL FOOTBALL | Immunohistochemistry | Head | Immunoglobulin G - blood | S100 Calcium Binding Protein beta Subunit | Autoantibodies - blood | Humans | Male | Nerve Growth Factors - immunology | Chromatography, High Pressure Liquid | Athletes | S100 Proteins - immunology | Football | Blotting, Western | Diffusion Tensor Imaging | Young Adult | Blood-Brain Barrier - pathology | Mass Spectrometry | S100 Proteins - blood | Adolescent | Nerve Growth Factors - blood | Brain | Football (College) | Sports injuries | Autoantibodies | Concussion | Football teams | Neuroimaging | Traumatic brain injury | Cognitive ability | S100b protein | Antibodies | Neurosurgery | Proteins | Head injuries | Blood-brain barrier | Etiology | Tomography | Neurological disorders | Players | Damage assessment | Immune response | Abnormalities | Health risks | Permeability | Substantia alba | Surges | Trauma | Neurological diseases | Immune systems | Medicine | Serum levels | Hypotheses | Brain research | Damage detection | Magnetic resonance imaging | Correlation analysis | Neurological complications | Games | Alzheimers disease | Immunoassays | Index Medicus
Journal Article
Stroke, ISSN 0039-2499, 09/2017, Volume 48, Issue 9, pp. 2419 - 2425
BACKGROUND AND PURPOSE—Stroke diagnosis could be challenging in the acute phase. We aimed to develop a blood-based diagnostic tool to differentiate between... 
diagnosis | cerebral hemorrhage | hypertension | stroke | biomarkers | METAANALYSIS | NATRIURETIC PEPTIDES | MIMICS | TIME | CLINICAL NEUROLOGY | THERAPY | ACUTE ISCHEMIC-STROKE | THROMBOLYSIS | PERIPHERAL VASCULAR DISEASE | BRAIN | Prospective Studies | Fibrin Fibrinogen Degradation Products - metabolism | Humans | Middle Aged | Stroke - diagnosis | Fas Ligand Protein - blood | Insulin-Like Growth Factor Binding Protein 3 - blood | Male | Case-Control Studies | Neural Cell Adhesion Molecules - blood | Cerebral Hemorrhage - diagnosis | S100 Calcium Binding Protein beta Subunit - blood | Cerebral Hemorrhage - blood | Brain Ischemia - blood | Caspase 3 - blood | Interleukin-6 - blood | Phosphopyruvate Hydratase - blood | Peptide Fragments - blood | Aged, 80 and over | Female | Odds Ratio | Natriuretic Peptide, Brain - blood | Matrix Metalloproteinase 9 - blood | von Willebrand Factor - metabolism | Cell Adhesion Molecules - blood | Interleukin-17 - blood | Receptors, Tumor Necrosis Factor, Type I - blood | Apolipoprotein C-III - blood | Logistic Models | Chemokine CXCL1 - blood | Biomarkers - blood | Fibronectins - blood | Stroke - blood | HSC70 Heat-Shock Proteins - blood | Nerve Growth Factor - blood | Interleukin Receptor Common gamma Subunit - blood | Amine Oxidase (Copper-Containing) - blood | Brain Ischemia - diagnosis | Endostatins - blood | ROC Curve | Aged | Index Medicus
Journal Article