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CURRENT BIOLOGY, ISSN 0960-9822, 04/2000, Volume 10, Issue 8, pp. 439 - 448
Journal Article
Neuron, ISSN 0896-6273, 2006, Volume 51, Issue 4, pp. 417 - 429
Efflux of dopamine through the dopamine transporter (DAT) is critical for the psychostimulatory properties of amphetamines, but the underlying mechanism is... 
CELLBIO | SIGNALING | DENSIN-180 | CARRIER-MEDIATED RELEASE | EXCHANGE DIFFUSION | EFFLUX | MECHANISM | NEUROTRANSMITTER RELEASE | PHOSPHORYLATION | 3,4-METHYLENEDIOXYMETHAMPHETAMINE | NEUROSCIENCES | PARA-METHOXYAMPHETAMINE | NA+ SIGNALS | Dopamine Plasma Membrane Transport Proteins - metabolism | Central Nervous System Stimulants - pharmacology | Chromatography, High Pressure Liquid - methods | Mesencephalon - cytology | Amphetamines - pharmacology | Humans | Dopamine Plasma Membrane Transport Proteins - chemistry | Patch-Clamp Techniques - methods | Transfection - methods | Protein Binding - drug effects | Calcium-Calmodulin-Dependent Protein Kinases - pharmacology | Neurons - physiology | Biological Transport - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Calcium-Calmodulin-Dependent Protein Kinase Type 2 | Dopamine - metabolism | Animals, Newborn | Membrane Potentials - drug effects | Blotting, Western - methods | Immunoprecipitation - methods | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Membrane Potentials - physiology | Sulfonamides - pharmacology | Dopamine Plasma Membrane Transport Proteins - genetics | Immunohistochemistry - methods | Animals | In Vitro Techniques | Benzylamines - pharmacology | Protein Binding - physiology | Protein Structure, Tertiary - physiology | Legislators | Medical colleges | Pharmacogenetics | Neurosciences | Dopamine | Neurons | Phenols | Protein kinases | Central nervous system agents | Calmodulin | Proteins | Electrodes | Phosphorylation | Methamphetamines | Cloning | Cocaine | Kinases | Experiments | Variance analysis
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 08/2010, Volume 49, Issue 8, pp. 771 - 782
Journal Article
Journal Article
Journal of Periodontology, ISSN 0022-3492, 03/2014, Volume 85, Issue 3, pp. 498 - 508
Background: Previous studies have shown that periodontal ligament exists in a hypoxic microenvironment, especially under the condition of periodontitis or... 
mitogen‐activated protein kinases | stress | cell proliferation | periodontal ligament | mechanical | Cell differentiation | cell hypoxia | Cell proliferation | Periodontal ligament | Mitogen-Activated protein kinases | Mechanical | Cell hypoxia | Stress | INDUCIBLE FACTOR-1-ALPHA | MAP-KINASES | IN-VITRO | mitogen-activated protein kinases | MECHANICAL-STRESS | DENTISTRY, ORAL SURGERY & MEDICINE | EPIDERMAL-GROWTH-FACTOR | ENDOTHELIAL-CELLS | TOOTH MOVEMENT | SMOOTH-MUSCLE-CELLS | UP-REGULATION | EXPRESSION | Hypoxia-Inducible Factor 1, alpha Subunit - analysis | Cell Hypoxia - physiology | MAP Kinase Signaling System - physiology | Osteogenesis - physiology | Cell Proliferation | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Core Binding Factor Alpha 1 Subunit - analysis | Male | Periodontal Ligament - cytology | Time Factors | Calcium-Calmodulin-Dependent Protein Kinases - pharmacology | Cellular Microenvironment - physiology | Female | Cell Culture Techniques | Cell Differentiation - physiology | Child | Periodontal Ligament - physiopathology | Tensile Strength | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Cells, Cultured | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Flavonoids | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Adolescent | Sp7 Transcription Factor | Protein Kinase Inhibitors - pharmacology | Transcription Factors - analysis | Osteopontin - analysis
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 04/2010, Volume 337, Issue 1-2, pp. 223 - 237
We have previously shown that metoprolol can inhibit carnitine palmitoyltransferase-1 catalytic activity and decrease its malonyl CoA sensitivity within 30... 
Cardiac metabolism | Peroxynitrite | Kinase scaffolding protein | Carnitine palmitoyltransferase-1 | Protein kinase | Nitric oxide | HEART | CONFOCAL IMAGES | RAT | METABOLISM | LIVER | CELL BIOLOGY | Protein Kinases - metabolism | Cell Fractionation | Mitochondria, Heart - metabolism | Cyclic AMP-Dependent Protein Kinases - pharmacology | Rats, Wistar | Oncogene Protein v-akt - physiology | Male | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - pharmacology | Mitochondria, Heart - drug effects | Nitroprusside - pharmacology | Dose-Response Relationship, Drug | Tissue Distribution | Malonyl Coenzyme A - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - physiology | Carnitine O-Palmitoyltransferase - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Oncogene Protein v-akt - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Protein Kinases - pharmacology | p38 Mitogen-Activated Protein Kinases - physiology | Mitochondria, Heart - enzymology | Rats | Oncogene Protein v-akt - pharmacology | p38 Mitogen-Activated Protein Kinases - pharmacology | Cyclic AMP-Dependent Protein Kinases - physiology | Animals | Peroxynitrous Acid - pharmacology | Protein Kinases - physiology | In Vitro Techniques | Nitrogen oxide | Proteins | Thiols | Analysis | Sodium nitroferricyanide | Mitochondrial DNA | Protein kinases | Carnitine | Heart | Enzymes | Mitochondria | Kinases | Metabolism | Index Medicus
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2007, Volume 43, Issue 3, pp. 281 - 291
Journal Article
Leukemia, ISSN 0887-6924, 03/2009, Volume 23, Issue 3, pp. 477 - 485
The detailed molecular mechanism of action of second-generation BCR-ABL tyrosine kinase inhibitors, including perturbed targets and pathways, should contribute... 
BCR-ABL INHIBITORS | SRC | TYROSINE KINASE | MECHANISMS | NILOTINIB | BREAST-CANCER CELLS | dasatinib | ONCOLOGY | IMATINIB | kinase profiling | RESISTANCE | chronic myeloid leukemia | chemical proteomics | SKI-606 | HEMATOLOGY | bosutinib | Nitriles - pharmacology | Proto-Oncogene Proteins c-abl - antagonists & inhibitors | Humans | Substrate Specificity | Neoplasm Proteins - antagonists & inhibitors | Gene Expression Profiling | K562 Cells - drug effects | Quinolines - pharmacology | Drug Delivery Systems | Leukemia, Myeloid, Accelerated Phase - pathology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Dasatinib | Nerve Tissue Proteins - antagonists & inhibitors | Aniline Compounds - pharmacology | Leukocytes, Mononuclear - drug effects | Quinolines - chemistry | src-Family Kinases - antagonists & inhibitors | Pyrimidines - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | K562 Cells - enzymology | Leukemia, Myeloid, Accelerated Phase - enzymology | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - drug effects | Fusion Proteins, bcr-abl - antagonists & inhibitors | Nitriles - chemistry | Leukocytes, Mononuclear - enzymology | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Aniline Compounds - chemistry | Drug Screening Assays, Antitumor | Protein-Tyrosine Kinases - antagonists & inhibitors | Enzyme inhibitors | Physiological aspects | Chronic myeloid leukemia | Research | Drug therapy | Health aspects | Protein kinases
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 03/2010, Volume 112, Issue 6, pp. 1562 - 1573
P>Calcium/calmodulin-dependent serine kinase (CASK), a causative gene in X-linked mental retardation, acts as a multi-domain scaffold protein and interacts... 
Protein kinase A phosphorylation | Calcium/calmodulin-dependent serine kinase | NMDA receptor | T-brain-1 | COMPLEX | calcium | SYNAPTIC FUNCTION | MENTAL-RETARDATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | BINDING PROTEIN | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | calmodulin-dependent serine kinase | BASOLATERAL MEMBRANE | CASK/LIN-2 | protein kinase A phosphorylation | EPITHELIAL-CELLS | HEPARAN-SULFATE PROTEOGLYCAN | BRAIN | Disks Large Homolog 4 Protein | Guanylate Kinases - genetics | Immunoprecipitation | Cricetulus | Cyclic AMP-Dependent Protein Kinases - pharmacology | Receptors, N-Methyl-D-Aspartate - metabolism | Mutagenesis, Site-Directed - methods | Intracellular Signaling Peptides and Proteins - metabolism | Neuroblastoma | Phosphoproteins - metabolism | Threonine - metabolism | Receptors, N-Methyl-D-Aspartate - genetics | Brain - metabolism | Isoquinolines - pharmacology | Transfection - methods | Threonine - genetics | Membrane Proteins - metabolism | Neurons - metabolism | Phosphorylation - drug effects | Tetrodotoxin - pharmacology | Neurons - drug effects | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Syndecan-2 - metabolism | Cell Line | Brain - cytology | Cricetinae | Enzyme Inhibitors - pharmacology | Rats | Mutation - genetics | Sulfonamides - pharmacology | Serine - metabolism | T-Box Domain Proteins - metabolism | Cyclic AMP - pharmacology | Gene Expression Regulation - drug effects | Nerve Tissue Proteins - metabolism | Up-Regulation - drug effects | Animals | Zonula Occludens-1 Protein | Signal Transduction - drug effects | Guanylate Kinases - metabolism | Signal Transduction - physiology | Post-translational modification | Cellular proteins | Methyl aspartate | Genetic research | Cyclic adenylic acid | Protein kinases | Mental illness | Proteins | Neurology | Calcium | Kinases | Intellectual disabilities | Genes | Index Medicus
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 67, Issue 2, pp. 239 - 252
The Ca /calmodulin-dependent protein kinase II (CaMKII) is critically required for the synaptic recruitment of AMPA-type glutamate receptors (AMPARs) during... 
MOLNEURO | SIGNALING | Signaling | Molneuro | GLUTAMATE-RECEPTOR | DENDRITIC SPINES | LATERAL MOVEMENTS | NONSYNAPTIC SITES | PAIRED-PULSE FACILITATION | LONG-TERM POTENTIATION | SYNAPTIC PLASTICITY | NEUROSCIENCES | CULTURED HIPPOCAMPAL-NEURONS | POSTSYNAPTIC DENSITY | PROTEIN-KINASE-II | Disks Large Homolog 4 Protein | Phosphorylation - physiology | Action Potentials - genetics | Calcium Channels - metabolism | Calcium - metabolism | Embryo, Mammalian | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Excitatory Postsynaptic Potentials - drug effects | Transfection - methods | Statistics, Nonparametric | Membrane Proteins - metabolism | Neurons - metabolism | Phosphorylation - drug effects | Diffusion | Neurons - drug effects | Electric Stimulation - methods | Receptors, AMPA - genetics | Action Potentials - drug effects | Excitatory Postsynaptic Potentials - genetics | Receptors, AMPA - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Animals, Newborn | Cells, Cultured | Rats | Enzyme Activation - drug effects | Hippocampus - cytology | Sulfonamides - pharmacology | Benzothiadiazines - pharmacology | Rats, Sprague-Dawley | Protein Transport | Animals | Models, Biological | Protein Kinase Inhibitors - pharmacology | Benzylamines - pharmacology | Receptors, AMPA - antagonists & inhibitors | Glutamate | Protein kinases | Proteins | Studies | Medical research | Phosphorylation | Trapping | Quantum dots | Kinases
Journal Article
Circulation Research, ISSN 0009-7330, 12/2009, Volume 105, Issue 12, pp. 1204 - 1212
RATIONALE:Angiotensin (Ang) II–induced apoptosis was reported to be mediated by different signaling molecules. Whether these molecules are either... 
Reactive oxygen species | CaMKII | Angiotensin II | Apoptosis | CARDIAC & CARDIOVASCULAR SYSTEMS | P38 MAPK | INHIBITION PROTECTS | apoptosis | VENTRICULAR MYOCYTES | CELL-DEATH | PHOSPHOLAMBAN PHOSPHORYLATION | HEART-DISEASE | METHIONINE OXIDATION | angiotensin II | reactive oxygen species | PERIPHERAL VASCULAR DISEASE | INDEPENDENT ACTIVATION | HEMATOLOGY | Free Radical Scavengers - pharmacology | Tiopronin - pharmacology | Reactive Oxygen Species - metabolism | Rats, Wistar | Species Specificity | Apoptosis - drug effects | Calcium - metabolism | NADPH Oxidases - metabolism | Peptides - genetics | Myocytes, Cardiac - enzymology | Time Factors | Egtazic Acid - analogs & derivatives | p38 Mitogen-Activated Protein Kinases - metabolism | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - metabolism | Cats | Calmodulin - metabolism | Angiotensin II - metabolism | Cell Survival | NADPH Oxidases - antagonists & inhibitors | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Chelating Agents - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Peptides - pharmacology | Myocytes, Cardiac - pathology | Animals | Egtazic Acid - pharmacology | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Pyridines - pharmacology | Enzyme Activation | Oxidative Stress - drug effects | Benzylamines - pharmacology | Calmodulin - antagonists & inhibitors
Journal Article