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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 10, pp. 3841 - 3846
The S100A8/S100A9 heterodime/calprotectin (CP) functions in the host response to pathogens through a mechanism termed "nutritional immunity." CP binds Mn²⁺ and... 
Proteins | Pathogens | Antimicrobials | Superoxides | Neutrophils | Bacteria | Infections | Titration | Immunity | Crystal structure | Bacterial pathogenesis | Isothermal titration calorimetry | Protein crystal structure | Staphylococcus aureus | Antibiotic resistance | CRYSTAL-STRUCTURE | PROTEINS 8 | MULTIDISCIPLINARY SCIENCES | protein crystal structure | ESCHERICHIA-COLI | PSORIASIN S100A7 | ZINC | isothermal titration calorimetry | STRUCTURE VALIDATION | antibiotic resistance | CALCIUM | STAPHYLOCOCCUS-AUREUS | bacterial pathogenesis | SUPEROXIDE-DISMUTASE | BINDING | Zinc - metabolism | Humans | Protein Multimerization | Crystallography, X-Ray | Calgranulin A - genetics | Leukocyte L1 Antigen Complex - immunology | Host-Pathogen Interactions - immunology | Calgranulin A - chemistry | Calgranulin B - immunology | Calgranulin B - genetics | Leukocyte L1 Antigen Complex - pharmacology | Calgranulin A - immunology | Binding Sites | Calgranulin B - chemistry | Mutagenesis, Site-Directed | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Recombinant Proteins - pharmacology | Immunity, Innate | Manganese - metabolism | Recombinant Proteins - immunology | Leukocyte L1 Antigen Complex - chemistry | Leukocyte L1 Antigen Complex - genetics | Staphylococcus aureus - immunology | Histidine - chemistry | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Amino Acid Substitution | Molecular dynamics | Host-parasite relationships | Immune response | Research | Health aspects | Biological Sciences
Journal Article
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 06/2010, Volume 50, pp. E116 - E116
Journal Article
Journal of Pediatric Gastroenterology and Nutrition, ISSN 0277-2116, 06/2010, Volume 50, pp. E116 - E117
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 541 - 554
Elevated concentrations of tumor necrosis factor-α (TNF-α) are detected in pathologies characterized by chronic inflammation. Whether TNF-α plays a role in... 
RECRUITMENT | KILLER-CELL | IMMUNE SUPPRESSION | IMMUNOSUPPRESSION | DOWN-REGULATION | TNF-ALPHA | ACCUMULATION | IMMUNOLOGY | CANCER | T-CELLS | PROGRESSION | Calgranulin B - metabolism | Calgranulin A - metabolism | Tumor Necrosis Factor-alpha - genetics | Immunoblotting | Calgranulin A - genetics | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Cell Differentiation - genetics | Inflammation - metabolism | Flow Cytometry | Etanercept | T-Lymphocytes - metabolism | Myeloid Cells - immunology | Calgranulin B - immunology | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Immunoglobulin G - pharmacology | Killer Cells, Natural - immunology | Myeloid Cells - drug effects | Receptors, Antigen, T-Cell - immunology | Calgranulin B - genetics | Mitogen-Activated Protein Kinases - immunology | Calgranulin A - immunology | Receptors, Antigen, T-Cell - metabolism | Mice, Inbred C57BL | Cells, Cultured | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Cell Differentiation - immunology | Animals | Receptors, Tumor Necrosis Factor | Cell Differentiation - drug effects | Inflammation - genetics | Myeloid Cells - metabolism | Mitogen-Activated Protein Kinases - genetics | T-Lymphocytes - immunology | Mice | Mice, Inbred BALB C | Receptors, Antigen, T-Cell - genetics | Killer Cells, Natural - metabolism | Chronic Disease | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Mitogen-Activated Protein Kinases - metabolism
Journal Article
EMBO Journal, ISSN 0261-4189, 2013, Volume 32, Issue 1, pp. 100 - 111
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2013, Volume 123, Issue 11, pp. 4595 - 4611
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2018, Volume 128, Issue 5, pp. 1852 - 1866
Autoimmune diseases, such as psoriasis and arthritis, show a patchy distribution of inflammation despite systemic dysregulation of adaptive immunity. Thus,... 
MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-NECROSIS-FACTOR | CRYSTAL-STRUCTURE | DEFICIENT MICE | TNF-ALPHA | NONCOVALENTLY LINKED TETRAMERS | MOLECULAR-BASIS | MRP14 | S100A9 | DISEASE-ACTIVITY | PROTEIN COMPLEX | Inflammation - pathology | Proto-Oncogene Proteins c-mdm2 - genetics | Calgranulin A - genetics | Arthritis - genetics | Calgranulin A - chemistry | Psoriasis - genetics | Psoriasis - pathology | Calgranulin B - immunology | Arthritis - immunology | Calgranulin B - genetics | Calgranulin A - immunology | Binding Sites | Calgranulin B - chemistry | Psoriasis - immunology | Alarmins - genetics | Arthritis - pathology | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Alarmins - chemistry | Mice, Knockout | Animals | Proto-Oncogene Proteins c-mdm2 - immunology | Inflammation - genetics | Mice | Alarmins - immunology | Prevention | Cellular proteins | Phagocytes | Mediators | Physiological aspects | Development and progression | Inflammation | Health aspects | Psoriasis | Calcium | Disease | Mass spectroscopy | Arthritis | Adaptive immunity | TLR4 protein | Tumor necrosis factor-α | Kinases | Inflammatory diseases | Proteins | Toll-like receptors | Scientific imaging | Autoimmune diseases | Mass spectrometry | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
Journal Article
Amino Acids, ISSN 0939-4451, 10/2011, Volume 41, Issue 4, pp. 821 - 842
Journal Article