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Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 138, Issue 1, pp. 130 - 141.e9
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 08/2011, Volume 18, Issue 8, pp. 1356 - 1365
We have recently reported that the bioactive lipid sphingosine-1-phosphate (S1P), usually signaling proliferation and anti-apoptosis induces neuronal death... 
neurodegeneration | calpain | apoptosis | cis-4-methylsphingosine | release | Sphingosine-1-phosphate | Ca2+-release | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FUNCTIONAL-CHARACTERIZATION | SPHINGOSINE 1-PHOSPHATE | CELL BIOLOGY | SPHINGOLIPID METABOLISM | CYTOCHROME-C | POSTMITOTIC NEURONS | AMYLOID-BETA | CELL-CYCLE | MOLECULAR-CLONING | Lysophospholipids - metabolism | Neurons - pathology | Calpain - metabolism | Caspase 9 - metabolism | Calcium - metabolism | tau Proteins - metabolism | Calpain - genetics | Nerve Degeneration - chemically induced | Nerve Degeneration - metabolism | Neurons - physiology | Sphingosine - metabolism | Aldehyde-Lyases - genetics | Neurons - drug effects | Mice, Inbred C57BL | Phosphotransferases (Alcohol Group Acceptor) - genetics | Mitochondria - metabolism | Caspase 12 - metabolism | Nerve Degeneration - pathology | Cyclin-Dependent Kinase 5 - metabolism | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Sphingosine - pharmacology | Sphingosine - analogs & derivatives | Animals | Cerebellum - cytology | Aldehyde-Lyases - metabolism | Cell Cycle - physiology | Glycosphingolipids - metabolism | Signal Transduction - physiology | Mice | Apoptosis - physiology | Sphingosine - chemistry | Cerebellum | Phosphorylation | Calcium | Central nervous system | Cysteine proteinase | Caspase | Calpain | Lipids | Anatomy | Metabolism | Cyclin-dependent kinase 5 | Sphingosine 1-phosphate | Neurotoxicity | Glycosphingolipids | Tau protein | Neurodegeneration | Phosphate | Cell cycle | Endoplasmic reticulum | Index Medicus | Original Paper
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 2013, Volume 80, Issue 5, pp. 1175 - 1189
Axon degeneration is widespread both in neurodegenerative disease and in normal neural development, but the molecular pathways regulating these degenerative... 
SYSTEM | ACTIVATION | WALLERIAN DEGENERATION | PROTEASOME | INVOLVEMENT | DEGRADATION | DEATH | MECHANISMS | CLEAVAGE | FRAGMENTATION | NEUROSCIENCES | Neurons - pathology | Calpain - metabolism | Wallerian Degeneration - pathology | Cytoskeletal Proteins - genetics | Embryo, Mammalian | Nicotinamide-Nucleotide Adenylyltransferase - metabolism | Humans | Cell Survival - genetics | Ganglia, Spinal - cytology | Green Fluorescent Proteins - genetics | Armadillo Domain Proteins - genetics | RNA, Messenger - metabolism | Sciatic Neuropathy - complications | Nerve Degeneration - metabolism | Axotomy | Neurons - ultrastructure | Time Factors | HEK293 Cells | Cytoskeletal Proteins - metabolism | Disease Models, Animal | Animals, Newborn | Calcium-Binding Proteins - metabolism | Green Fluorescent Proteins - metabolism | Microscopy, Electron, Transmission | Brain - cytology | Nerve Growth Factor - metabolism | Transduction, Genetic | Wallerian Degeneration - physiopathology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Gene Expression Regulation - physiology | Ganglia, Spinal - ultrastructure | Nerve Tissue Proteins - metabolism | Animals | Armadillo Domain Proteins - metabolism | Nicotinamide-Nucleotide Adenylyltransferase - genetics | Mice | In Vitro Techniques | Nerve Degeneration - etiology | Sciatic Neuropathy - metabolism | Calcium-Binding Proteins - genetics | RNA, Small Interfering - metabolism | Physiological aspects | Calpain | Nervous system diseases | Analysis | Medical research | Microscopy | Mammals | Neurodegeneration | Lasers
Journal Article
Toxicology, ISSN 0300-483X, 2012, Volume 291, Issue 1-3, pp. 1 - 9
Abstract Anti-cancer drugs such as vincristine, paclitaxel, oxaliplatin, cisplatin and bortezomib are well reported to exert direct and indirect effects on... 
Emergency | Oxidative stress | Mitochondria | Cancer-chemotherapeutic drugs | Inflammation | Calcium | Peripheral neuropathy | INDUCED PAINFUL NEUROPATHY | HEAT HYPERALGESIA | GATED SODIUM-CHANNELS | SPINAL-CORD | VINCRISTINE NEUROPATHY | DORSAL-ROOT GANGLION | SENSORY NEURONS | LANGERHANS CELLS | MITOCHONDRIAL PERMEABILITY TRANSITION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CUTANEOUS INNERVATION | Inflammation - chemically induced | Inflammation - pathology | Peripheral Nervous System Diseases - chemically induced | Calpain - metabolism | Calcium - metabolism | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Nerve Fibers - drug effects | Neuropeptides - metabolism | Mitochondria - drug effects | Receptors, Serotonin - metabolism | Antineoplastic Agents - toxicity | Potassium Channels - metabolism | TRPV Cation Channels - metabolism | Animals | Caspases - metabolism | Protein Kinase C - metabolism | Sodium Channels - metabolism | Peripheral Nervous System Diseases - pathology | Nitric Oxide - metabolism | Mitogen-Activated Protein Kinases - metabolism | Care and treatment | Peptides | Neurons | Mitochondrial DNA | Permeability | Glutamate | Arachidonic acid | Cyclic guanylic acid | Cytochrome c | Methyl aspartate | Chemotherapy | Pain | Nitric oxide | Health aspects | Protein kinases | Mitogens | Free radicals (Chemistry) | Cancer | Index Medicus
Journal Article
Cardiovascular Research, ISSN 0008-6363, 2/2009, Volume 81, Issue 3, pp. 439 - 448
Journal Article
Journal of Applied Physiology, ISSN 1522-1601, 2007, Volume 103, Issue 5, pp. 1744 - 1751
Journal Article
Journal of Applied Physiology, ISSN 8750-7587, 11/2013, Volume 115, Issue 10, pp. 1496 - 1505
Although it is well established that carbohydrate and lipid metabolism are profoundly altered by cold stress, the effects of short-term cold exposure on protein metabolism in skeletal muscle are still poorly understood... 
Protein degradation | Cold | Muscle RING finger enzyme-1 | Atrogin-1 | Protein synthesis | SPORT SCIENCES | PHYSIOLOGY | atrogin-1 | ATROPHY | protein synthesis | cold | FOXO TRANSCRIPTION FACTORS | UBIQUITIN LIGASES | CALPAIN ISOFORMS | PATHWAY | DEGRADATION | muscle RING finger enzyme-1 | YOUNG-RATS | ENERGY-METABOLISM | EXPRESSION | protein degradation | ADIPOSE-TISSUE | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Calpain - metabolism | Rats, Wistar | SKP Cullin F-Box Protein Ligases - genetics | Male | Muscle, Skeletal - metabolism | RNA, Messenger - metabolism | Tripartite Motif Proteins | Cold-Shock Response | Lysosomes - metabolism | Forkhead Transcription Factors - metabolism | Proteolysis | Muscle Proteins - metabolism | Microfilament Proteins - metabolism | Hormones - blood | Proto-Oncogene Proteins c-akt - metabolism | Calcium-Binding Proteins - metabolism | Cold Temperature | Signal Transduction | Ubiquitin-Protein Ligases - metabolism | Rats | Acclimatization | SKP Cullin F-Box Protein Ligases - metabolism | Muscle Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Carrier Proteins - metabolism | Ubiquitin-Protein Ligase Complexes - metabolism | Kinetics | Proteasome Endopeptidase Complex - metabolism | Ubiquitin-Protein Ligases - genetics
Journal Article
Cell death and differentiation, ISSN 1476-5403, 2006, Volume 14, Issue 4, pp. 775 - 784
Nine-day-old harlequin (Hq) mice carrying the hypomorphic apoptosis-inducing factor (AIF)(Hq) mutation expressed 60% less AIF, 18% less respiratory chain... 
CALPAIN | RAT | BIOCHEMISTRY & MOLECULAR BIOLOGY | MITOCHONDRIA | FREE-RADICAL SCAVENGER | edaravone | caspase inhibitor | MECHANISMS | harlequin | DEVELOPING BRAIN | DAMAGE | CELL-DEATH | CELL BIOLOGY | CASPASE-3 ACTIVATION | CYCLOSPORINE-A | free radical | oxidative stress | Free Radical Scavengers - pharmacology | Neurons - pathology | Oxidative Stress | Apoptosis - drug effects | Antipyrine - pharmacology | Apoptosis Inducing Factor - deficiency | Male | Hypoxia-Ischemia, Brain - pathology | Hypoxia-Ischemia, Brain - genetics | Quinolines - pharmacology | Caspases - metabolism | Antipyrine - analogs & derivatives | Amino Acid Chloromethyl Ketones - pharmacology | Mice, Mutant Strains | Female | Neurons - metabolism | Neurons - drug effects | Hypoxia-Ischemia, Brain - metabolism | Apoptosis Inducing Factor - metabolism | Animals, Newborn | Cytochromes c - metabolism | Necrosis - metabolism | Mitochondria - metabolism | Caspase Inhibitors | Animals | Mice | Necrosis - genetics | Antipyrine/analogs & derivatives/pharmacology | Hypoxia-Ischemia | Neurosciences | Free Radical Scavengers/pharmacology | Apoptosis Inducing Factor/deficiency/metabolism | Mitochondria/metabolism | Caspases/antagonists & inhibitors/metabolism | Necrosis/genetics/metabolism | Fysiologi | Apoptosis/drug effects | Brain/genetics/metabolism/pathology | Cytochromes c/metabolism | Quinolines/pharmacology | Newborn | Neurons/drug effects/metabolism/pathology | Mutant Strains | Physiology | Amino Acid Chloromethyl Ketones/pharmacology | Neurovetenskaper
Journal Article
Journal Article