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Drug Metabolism and Disposition, ISSN 0090-9556, 11/2017, Volume 45, Issue 11, pp. 1166 - 1177
Multidrug resistance (MDR) caused by the overexpression of ATP-binding cassette (ABC) transporters in cancer cells is a major obstacle in cancer chemotherapy.... 
VITRO | CELLS | ABCB1 | HUMAN P-GLYCOPROTEIN | TURMERIC POWDER | IN-VIVO | PHARMACOLOGY & PHARMACY | CHEMOPREVENTIVE AGENT CURCUMIN | BIOCHEMICAL-MECHANISM | CANCER | PROTEIN-1 ABCC1 | Curcumin - analogs & derivatives | Humans | Biological Availability | Neoplasm Proteins - antagonists & inhibitors | Prazosin - analogs & derivatives | Neoplasm Proteins - metabolism | Azides - chemistry | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - metabolism | Flow Cytometry | Biological Transport | Antineoplastic Agents - pharmacology | Benzene Derivatives | Camptothecin - analogs & derivatives | Ketones | Curcumin - pharmacology | Neoplasm Proteins - chemistry | Prazosin - chemistry | Drug Synergism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - antagonists & inhibitors | ATP Binding Cassette Transporter, Sub-Family B - metabolism | ATP Binding Cassette Transporter, Sub-Family G, Member 2 - chemistry | Cell Line, Tumor | Mitoxantrone - pharmacokinetics | Camptothecin - pharmacology | Drug Resistance, Neoplasm - drug effects | Efflux | Flow cytometry | Toxicity | Multidrug resistance | Cytotoxicity | Breast cancer | Bioavailability | Substrates | Modulators | Analogs | Cytometry | Chemotherapy | Diet | Curcumin | Mitoxantrone | ATP | Transporter | Binding sites | Adenosine triphosphatase | Cancer | Index Medicus
Journal Article
Journal Article
Chemistry - A European Journal, ISSN 0947-6539, 01/2014, Volume 20, Issue 2, pp. 591 - 597
We have developed a catalytic asymmetric synthesis of (S)-4-ethyl-6,6-(ethylenedioxy)-7,8-dihydro-4-hydroxy-1H-pyrano[3,4-f]indolizine-3,10(4H)dione (5a), a... 
Camptothecin | Urea | Natural products | Organocatalysis | Guanidine | Synthesis | Hydroxylation | Enantiomers | Resveratrol | Organic compounds | Asymmetry | Catalysts | Oxidation | Derivatives | Catalysis | Lactones
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 02/2013, Volume 21, Issue 3, pp. 814 - 823
Journal Article
Theoretical Chemistry Accounts, ISSN 1432-881X, 10/2014, Volume 133, Issue 10, pp. 1 - 6
Journal Article
Tetrahedron: Asymmetry, ISSN 0957-4166, 06/2017, Volume 28, Issue 6, pp. 843 - 848
An efficient and stereocontrolled synthesis of (20 )-camptothecin and an analogue has been developed. The key feature of this synthesis is the organocatalyzed... 
(S)-CAMPTOTHECIN | CATALYTIC ENANTIOSELECTIVE SYNTHESIS | PRACTICAL SYNTHESIS | KEY INTERMEDIATE | CHEMISTRY, ORGANIC | CHEMISTRY, PHYSICAL | PLANT ANTITUMOR AGENTS | CAMPTOTHECIN INTERMEDIATE | BETA-KETO-ESTERS | HIGHLY EFFICIENT | CHEMISTRY, INORGANIC & NUCLEAR | PART 3 | 20(S)-CAMPTOTHECIN
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/1998, Volume 41, Issue 27, pp. 5410 - 5419
Journal Article