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Annals of the New York Academy of Sciences, ISSN 0077-8923, 01/2016, Volume 1364, Issue 1, pp. 11 - 24
Osteoimmunology is a field of research dedicated to the study of the interactions between the immune system and bone. Among the cells of the immune system that... 
T cells | Pacifici, R. 2015. T cells, osteoblasts, and osteocytes: interacting lineages key for the bone anabolic and catabolic activities of parathyroid hormone. In “MARROW,” ed. by M. Zaidi. Ann. N.Y. Acad. Sci. 1364: 11–24 | PTH | stromal cells | bone | osteoblasts | osteocytes | Pacifici, R. 2015. T cells, osteoblasts, and osteocytes: interacting lineages key for the bone anabolic and catabolic activities of parathyroid hormone. In “MARROW,” ed. by M. Zaidi. Ann. N.Y. Acad. Sci. 1364: 11-24 | Stromal cells | Osteocytes | Bone | T cells | Osteoblasts | C-REACTIVE PROTEIN | DIFFERENTIATED OSTEOBLASTS | CD40 LIGAND | BETA-CATENIN | TUMOR-NECROSIS-FACTOR | CANCELLOUS BONE | OSTEOCLAST FORMATION | IN-VIVO | ENDOCRINOLOGY & METABOLISM | TNF-ALPHA | POSTMENOPAUSAL WOMEN | Osteoblasts - secretion | Humans | T-Lymphocytes - metabolism | Parathyroid Hormone - metabolism | Bone Marrow Cells - immunology | Bone and Bones - metabolism | Osteocytes - immunology | Osteoblasts - cytology | Bone and Bones - cytology | Osteocytes - secretion | Parathyroid Hormone - secretion | T-Lymphocytes - secretion | Osteocytes - metabolism | Bone Marrow Cells - cytology | Osteocytes - cytology | Stromal Cells - metabolism | Bone Marrow Cells - pathology | Cytokines - secretion | Osteoblasts - immunology | Bone Morphogenetic Proteins - secretion | Cell Communication | Wnt Proteins - secretion | Stromal Cells - immunology | Genetic Markers | Parathyroid Hormone - immunology | Proto-Oncogene Proteins - secretion | Cell Lineage | Stromal Cells - secretion | Animals | T-Lymphocytes - cytology | Models, Biological | T-Lymphocytes - immunology | Bone and Bones - immunology | Osteoblasts - metabolism | Bone Remodeling | Bone Marrow Cells - metabolism | Stromal Cells - cytology | Parathyroid hormone | Immune systems | Biomedical materials | Lymphocytes | Biocompatibility | Bones | Mice | Hormones
Journal Article
Journal Article
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 06/2017, Volume 32, Issue 6, pp. 1320 - 1331
ABSTRACT Notch signaling is critical for osteoblastic differentiation; however, the specific contribution of individual Notch ligands is unknown. Parathyroid... 
NOTCH | OSTEOBLAST | STROMAL/STEM CELL | GENETIC ANIMAL MODELS | PARATHYROID HORMONE | BONE-MARROW NICHE | FACTOR RBP-J | SELF-RENEWAL | INDUCED OSTEOCLASTOGENESIS | TRABECULAR BONE | HEMATOPOIETIC STEM-CELLS | ENDOCRINOLOGY & METABOLISM | MICE | DIFFERENTIATION | NF-KAPPA-B | EXPRESSION | Jagged-1 Protein - metabolism | Cancellous Bone - metabolism | Growth Plate - diagnostic imaging | Cell Count | Parathyroid Hormone - pharmacology | Stem Cells - cytology | Osteoclasts - cytology | Stem Cells - metabolism | Cell Lineage - drug effects | X-Ray Microtomography | Cancellous Bone - cytology | Cancellous Bone - diagnostic imaging | Growth Plate - cytology | Bone Resorption - metabolism | Osteoblasts - cytology | Osteoblasts - drug effects | Osteogenesis - drug effects | Growth Plate - metabolism | Osteoclasts - metabolism | Animals | Cell Differentiation - drug effects | Models, Biological | Bone Resorption - pathology | Stem Cells - drug effects | Ligands | Mice | Osteoblasts - metabolism | Osteoclasts - drug effects | Bones | Parathyroid hormone | Density | Analysis | Stem cells | Osteoprogenitor cells | Flow cytometry | Mesenchyme | Homeostasis | Bone (trabecular) | CD45 antigen | Apposition | Bone resorption | Functional anatomy | Clonal deletion | Ataxin | Rodents | Skeleton | Jagged1 protein | Parathyroid | Age | Limbs | Bone turnover | Cre recombinase | Progeny | Bone mass | Osteoblastogenesis | Notch protein | STEM CELL | STROMAL
Journal Article
Biomaterials, ISSN 0142-9612, 2010, Volume 31, Issue 25, pp. 6502 - 6510
Abstract The need for bone repair has increased as the population ages. Stem cell-scaffold approaches hold immense promise for bone tissue engineering.... 
Advanced Basic Science | Dentistry | Umbilical cord stem cells | Calcium phosphate cement | Load-bearing | Injectable scaffold | Minimally-invasive | Osteogenic differentiation | MATERIALS SCIENCE, BIOMATERIALS | COMPOSITE SCAFFOLD | ENGINEERING, BIOMEDICAL | REGENERATION | OSTEOBLASTIC DIFFERENTIATION | BIOACTIVE CERAMICS | PROLIFERATION | MECHANICAL-PROPERTIES | CANCELLOUS BONE | MARROW STROMAL CELLS | HYDROXYAPATITE CEMENT | Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry | Tissue Engineering - methods | Cell Survival | Humans | Umbilical Cord - cytology | Cells, Cultured | Hexuronic Acids - administration & dosage | Calcium Phosphates - chemistry | Materials Testing | Hexuronic Acids - chemistry | Tissue Scaffolds - chemistry | Alginates - administration & dosage | Injections | Mesenchymal Stromal Cells - cytology | Hydrogel, Polyethylene Glycol Dimethacrylate - administration & dosage | Alginates - chemistry | Calcium Phosphates - administration & dosage | Glucuronic Acid - administration & dosage | Glucuronic Acid - chemistry | Osteogenesis | Bone and Bones - cytology | Calcium phosphate | Transplantation | Gene expression | Tissue engineering | Collagen | Stem cells | load-bearing | umbilical cord stem cells | bone tissue engineering | osteogenic differentiation | calcium phosphate cement | minimally invasive
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2017, Volume 31, Issue 3, pp. 1011 - 1027
In this study, we examined the functional importance of EZH2 during skeletal development and homeostasis using the conditional deletion of ( ) in early... 
Epigenetics | Conditional knockout | Skeletal development | Differentiation | Mesenchymal stem cells | RANK Ligand - metabolism | Cancellous Bone - metabolism | Mesoderm - cytology | Osteoclasts - cytology | Cancellous Bone - cytology | Mesenchymal Stromal Cells - cytology | Gene Deletion | Macrophage Colony-Stimulating Factor - genetics | Wnt Signaling Pathway | Enhancer of Zeste Homolog 2 Protein - genetics | Enhancer of Zeste Homolog 2 Protein - metabolism | Cancellous Bone - growth & development | Mice, Inbred C57BL | Cells, Cultured | Mesenchymal Stromal Cells - metabolism | Macrophage Colony-Stimulating Factor - metabolism | Osteoclasts - metabolism | RANK Ligand - genetics | Homozygote | Animals | Heterozygote | Mesoderm - metabolism | Mice | Bone Remodeling | Osteogenesis | Structural integrity | Deformation | Wnt protein | Mesenchyme | Homeostasis | Stem cell transplantation | Gene deletion | Bone (trabecular) | Remodeling | Growth plate | Biomedical materials | Bone growth | Clonal deletion | Rodents | Acid resistance | Computer architecture | Deletion | Bone marrow | Bone morphogenetic proteins | Biocompatibility | Bone (cortical) | TRANCE protein | Adipogenesis | Bone remodelling | Macrophage colony-stimulating factor | Mechanical properties | Crosslinking | Bone turnover | Gene expression | Signaling | Stem cells | Plates (structural members) | Weight reduction | Osteoclasts | Acid phosphatase (tartrate-resistant) | In vivo methods and tests | Bone | Acid phosphatase
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 10/2017, Volume 32, Issue 10, pp. 2087 - 2102
ABSTRACT Cell‐matrix interactions constitute a fundamental aspect of skeletal cell biology and play essential roles in bone homeostasis. These interactions are... 
OSTEOPROGENITOR | OSTEOBLAST | INTEGRIN‐LINKED KINASE (ILK) | CELL MIGRATION | ACTIN CYTOSKELETON | BONE FORMATION | INTEGRIN-LINKED KINASE (ILK) | MATRIX | OSTEOBLAST DIFFERENTIATION | ILK | PROLIFERATION | MESENCHYMAL STEM-CELLS | PSEUDOKINASE | ADHESION | ENDOCRINOLOGY & METABOLISM | GLYCOGEN-SYNTHASE KINASE | SKELETAL DEVELOPMENT | TRANSGENIC MICE | Protein-Serine-Threonine Kinases - deficiency | Bone Diseases, Metabolic - pathology | Stem Cells - cytology | Stem Cells - metabolism | Bone Morphogenetic Proteins - metabolism | Gene Deletion | Cancellous Bone - pathology | Female | Bone Diseases, Metabolic - enzymology | Protein-Serine-Threonine Kinases - metabolism | Wnt Signaling Pathway | Bone and Bones - cytology | Animals, Newborn | Osteoblasts - enzymology | Embryonic Development | Mice, Knockout | Cell Lineage | Osteoblasts - pathology | Animals | Calcification, Physiologic | Sp7 Transcription Factor - metabolism | Cytoskeleton - metabolism | Fetus - embryology | Enzyme Activation | Osteogenesis | Bones | Cellular signal transduction | Density | Analysis | Integrins | Smad protein | Leukocyte migration | Homeostasis | AKT protein | Bone (trabecular) | Osteoblasts | Cell adhesion & migration | Signal transduction | Bone histomorphometry | Bone growth | Actin | Mineralization | Cell adhesion | Bone morphogenetic proteins | Extracellular matrix | ILK protein | Cell survival | Bone remodelling | Bone turnover | Osteoid | Bone mass | Collagen | Cytoskeleton | Cell migration
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2012, Volume 7, Issue 3, p. e33179
Journal Article