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1. Full Text Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
by Sahin, Ugur and Derhovanessian, Evelyna and Miller, Matthias and Kloke, Björn-Philipp and Simon, Petra and Löwer, Martin and Bukur, Valesca and Tadmor, Arbel D and Luxemburger, Ulrich and Schrörs, Barbara and Omokoko, Tana and Vormehr, Mathias and Albrecht, Christian and Paruzynski, Anna and Kuhn, Andreas N and Buck, Janina and Heesch, Sandra and Schreeb, Katharina H and Müller, Felicitas and Ortseifer, Inga and Vogler, Isabel and Godehardt, Eva and Attig, Sebastian and Rae, Richard and Breitkreuz, Andrea and Tolliver, Claudia and Suchan, Martin and Martic, Goran and Hohberger, Alexander and Sorn, Patrick and Diekmann, Jan and Ciesla, Janko and Waksmann, Olga and Brück, Alexandra-Kemmer and Witt, Meike and Zillgen, Martina and Rothermel, Andree and Kasemann, Barbara and Langer, David and Bolte, Stefanie and Diken, Mustafa and Kreiter, Sebastian and Nemecek, Romina and Gebhardt, Christoffer and Grabbe, Stephan and Höller, Christoph and Utikal, Jochen and Huber, Christoph and Loquai, Carmen and Türeci, Özlem
Nature (London), ISSN 0028-0836, 07/2017, Volume 547, Issue 7662, pp. 222 - 226
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunotherapy - methods | Neoplasm Recurrence, Local - prevention & control | Antibodies, Monoclonal - pharmacology | Humans | Vaccination | Antibodies, Monoclonal - therapeutic use | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Epitopes - genetics | Mutation - genetics | B7-H1 Antigen - immunology | CD8 Antigens - immunology | RNA - genetics | beta 2-Microglobulin - deficiency | Cancer Vaccines - genetics | Epitopes - immunology | Cancer Vaccines - immunology | Cancer Vaccines - therapeutic use | Neoplasm Metastasis | Melanoma - genetics | Melanoma - immunology | T-Lymphocytes - immunology | Melanoma - therapy | Precision Medicine - methods | Prevention | Genetic aspects | RNA | Health aspects | Mutation (Biology) | Cancer | Antigens | PD-1 protein | Genomics | Melanoma | Lymphocytes T | T cell receptors | Vaccines | Metastasis | Epitopes | Ribonucleic acid--RNA | Patients | Immunity | Metastases | Lymphocytes | Immunotherapy | Infiltration | Mutation | Tumors | Index Medicus
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2. Full Text Technologies for enhanced efficacy of DNA vaccines
by Saade, Fadi and Petrovsky, Nikolai
Expert review of vaccines, ISSN 1476-0584, 02/2012, Volume 11, Issue 2, pp. 189 - 209
cytokine | vaccine | adjuvant | DNA | immunization | plasmid | electroporation | Life Sciences & Biomedicine | Immunology | Science & Technology | Vaccines, DNA - genetics | Immunization | Adjuvants, Immunologic - administration & dosage | Guinea Pigs | Cancer Vaccines - administration & dosage | Humans | Vaccines, DNA - immunology | Cancer Vaccines - adverse effects | Treatment Outcome | Clinical Trials as Topic | Electroporation - methods | Vaccines, DNA - administration & dosage | Adjuvants, Immunologic - adverse effects | Cancer Vaccines - genetics | Cancer Vaccines - immunology | Neoplasms - therapy | Animals | Neoplasms - immunology | Plasmids | Vaccines, DNA - adverse effects | Communicable Diseases - immunology | Mice | Cytokines - genetics | Cytokines - immunology | Medical research | Research | Vaccines | Contamination | Cancer vaccines | Anopheles | Codon | Genetic research | Medicine, Experimental | Genetic aspects | Gene therapy | Health aspects | Tumors | Cancer | Infectious diseases | Reviews | Immunogenicity | Therapeutic applications | Adjuvants | Electroporation | DNA vaccines | Models | Codons | Promoters | Index Medicus
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3. Full Text A novel HPV prophylactic peptide vaccine, designed by immunoinformatics and structural vaccinology approaches
by Negahdaripour, Manica and Eslami, Mahboobeh and Nezafat, Navid and Hajighahramani, Nasim and Ghoshoon, Mohammad Bagher and Shoolian, Eskandar and Dehshahri, Ali and Erfani, Nasrollah and Morowvat, Mohammad Hossein and Ghasemi, Younes
Infection, genetics and evolution, ISSN 1567-1348, 10/2017, Volume 54, pp. 402 - 416
Human papillomavirus (HPV) vaccine | Vaccine design | Minor capsid protein (L2) | Cervical cancer (CxCa) | Immunoinformatics | Life Sciences & Biomedicine | Infectious Diseases | Science & Technology | Papillomavirus Vaccines - genetics | Vaccines, Subunit - genetics | Humans | Epitopes, T-Lymphocyte - genetics | Epitopes, B-Lymphocyte - immunology | Papillomaviridae - genetics | Papillomaviridae - immunology | Epitopes, B-Lymphocyte - genetics | Flagellin - genetics | Malaria Vaccines - immunology | Capsid Proteins - immunology | Adjuvants, Immunologic - genetics | Oncogene Proteins, Viral - genetics | Epitopes, T-Lymphocyte - immunology | Computational Biology - methods | Flagellin - immunology | Vaccines, Subunit - chemistry | Vaccines, Subunit - immunology | Molecular Dynamics Simulation | Animals | Papillomavirus Vaccines - chemistry | Papillomavirus Infections - prevention & control | Papillomavirus Vaccines - immunology | Molecular Docking Simulation | Oncogene Proteins, Viral - immunology | Capsid Proteins - genetics | Malaria Vaccines - genetics | Prevention | Peptides | Viral proteins | Analysis | Molecular dynamics | Vaccines | T cells | Health aspects | Papillomavirus infections | Cervical cancer | Antigenic determinants | Cancer | Index Medicus
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4. Full Text Enhancement of therapeutic DNA vaccine potency by melatonin through inhibiting VEGF expression and induction of antitumor immunity mediated by CD8+ T cells
by Baghban Rahimi, Sanaz and Baghban Rahimi, Sanaz and Mohebbi, Alireza and Mohebbi, Alireza and Vakilzadeh, Gelareh and Vakilzadeh, Gelareh and Biglari, Peyvand and Biglari, Peyvand and Razeghi Jahromi, Soodeh and Razeghi Jahromi, Soodeh and Mohebi, Seyed Reza and Mohebi, Seyed Reza and Shirian, Sadegh and Shirian, Sadegh and Gorji, Ali and Gorji, Ali and Ghaemi, Amir and Ghaemi, Amir
Archives of virology, ISSN 0304-8608, 3/2018, Volume 163, Issue 3, pp. 587 - 597
Medical Microbiology | Infectious Diseases | Biomedicine | Virology | Life Sciences & Biomedicine | Science & Technology | Vaccines, DNA - genetics | Adjuvants, Immunologic - administration & dosage | Papillomavirus Vaccines - genetics | Epithelial Cells - drug effects | Tumor Necrosis Factor-alpha - genetics | Vaccination | Papillomavirus E7 Proteins - immunology | Vaccines, DNA - immunology | Human papillomavirus 16 - drug effects | Human papillomavirus 16 - immunology | Vascular Endothelial Growth Factor A - antagonists & inhibitors | Vascular Endothelial Growth Factor A - genetics | Vaccines, DNA - administration & dosage | Melatonin - administration & dosage | Papillomavirus E7 Proteins - genetics | Cancer Vaccines - genetics | T-Lymphocytes, Cytotoxic - drug effects | Tumor Necrosis Factor-alpha - immunology | Melatonin - immunology | Papillomavirus Infections - immunology | Female | Papillomavirus Infections - virology | Interferon-gamma - genetics | Interleukin-4 - genetics | Papillomavirus Vaccines - administration & dosage | T-Lymphocytes, Cytotoxic - immunology | Cancer Vaccines - administration & dosage | Mice, Inbred C57BL | Plasmids - immunology | Gene Expression Regulation | Vascular Endothelial Growth Factor A - immunology | Papillomavirus Infections - mortality | Tumor Burden | Cancer Vaccines - immunology | Interleukin-4 - immunology | Animals | Lymphocyte Activation - drug effects | Papillomavirus Infections - prevention & control | Epithelial Cells - immunology | Interferon-gamma - immunology | Plasmids - chemistry | Survival Analysis | Cell Line, Tumor | Papillomavirus Vaccines - immunology | Cell Proliferation - drug effects | Mice | Human papillomavirus 16 - genetics | Plasmids - administration & dosage | Melatonin | Endothelial growth factors | Analysis | DNA | Resveratrol | Genetic research | Vaccines | T cells | Health aspects | Papillomavirus infections | Cell proliferation | Cell survival | CD8 antigen | Cytotoxicity | Lymphocytes T | DNA vaccines | Tumor necrosis factor-α | Cancer vaccines | Human papillomavirus | Interleukin 4 | γ-Interferon | Combined vaccines | Interleukin 10 | Antitumor activity | Interferon | Lactic acid | Vascular endothelial growth factor | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
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5. Full Text Safety, efficacy, and immunogenicity of VGX-3100, a therapeutic synthetic DNA vaccine targeting human papillomavirus 16 and 18 E6 and E7 proteins for cervical intraepithelial neoplasia 2/3: a randomised, double-blind, placebo-controlled phase 2b trial
by Trimble, Cornelia L, Prof and Morrow, Matthew P, PhD and Kraynyak, Kimberly A, PhD and Shen, Xuefei, PhD and Dallas, Michael, PhD and Yan, Jian, PhD and Edwards, Lance, MD and Parker, R Lamar, MD and Denny, Lynette, MD and Giffear, Mary, BS and Brown, Ami Shah, PhD and Marcozzi-Pierce, Kathleen, MA and Shah, Divya, MS and Slager, Anna M, MS and Sylvester, Albert J, MS and Khan, Amir, PhD and Broderick, Kate E, PhD and Juba, Robert J, MSCEP and Herring, Timothy A, MPH and Boyer, Jean, PhD and Lee, Jessica, MPH and Sardesai, Niranjan Y, PhD and Weiner, David B, Prof and Bagarazzi, Mark L, MD
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 386, Issue 10008, pp. 2078 - 2088
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Human papillomavirus 18 - immunology | Humans | Papillomavirus E7 Proteins - immunology | Vaccines, DNA - immunology | Cervical Intraepithelial Neoplasia - drug therapy | Human papillomavirus 16 - immunology | Papillomavirus E7 Proteins - genetics | Young Adult | Cancer Vaccines - therapeutic use | Adult | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Human papillomavirus 18 - genetics | DNA-Binding Proteins - immunology | Papillomavirus Vaccines - therapeutic use | Double-Blind Method | Repressor Proteins - genetics | Treatment Outcome | Uterine Cervical Neoplasms - drug therapy | Vaccines, DNA - therapeutic use | DNA-Binding Proteins - genetics | Cervical Intraepithelial Neoplasia - virology | Cancer Vaccines - immunology | Repressor Proteins - immunology | Papillomavirus Infections - drug therapy | Uterine Cervical Neoplasms - virology | Papillomavirus Vaccines - immunology | Oncogene Proteins, Viral - immunology | Human papillomavirus 16 - genetics | Proteins | Cervix dysplasia | DNA | Clinical trials | Product development | Vaccines | Health aspects | Papillomavirus infections | Medical research | Analysis | Medicine, Experimental | Human papillomavirus | Immunization | Womens health | Immunotherapy | Genomes | Cervical cancer | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus
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