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1. Full Text Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections
by Tian, Chao and Hromatka, Bethann S and Kiefer, Amy K and Eriksson, Nicholas and Noble, Suzanne M and Tung, Joyce Y and Hinds, David A
Nature communications, ISSN 2041-1723, 12/2017, Volume 8, Issue 1, pp. 599 - 13
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tonsillitis - genetics | Otitis Media - surgery | Hepatitis B - genetics | Humans | Candidiasis, Vulvovaginal - genetics | Male | HLA Antigens - genetics | Rheumatic Fever - genetics | Tuberculin Test | Tuberculosis - diagnosis | Case-Control Studies | Pharyngitis - genetics | Streptococcal Infections - genetics | Hepatitis A - genetics | Sinusitis - genetics | Infections - genetics | Female | Otitis Media - genetics | Warts - genetics | Pneumonia - genetics | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease | Genome-Wide Association Study | Urinary Tract Infections - genetics | Mumps - genetics | Common Cold - genetics | Middle Ear Ventilation | Rubella - genetics | Scarlet Fever - genetics | Infectious Mononucleosis - genetics | Chickenpox - genetics | Tuberculosis - genetics | Meningitis, Bacterial - genetics | Tonsillectomy | Herpes Labialis - genetics | Herpes Zoster - genetics | Tonsillitis - surgery | Measles - genetics | Chronic Disease | Rubella | Yeast | Hepatitis A virus | Scarlet fever | Pathogenesis | Chronic infection | Amino acids | Mapping | Genomes | Infections | Urinary tract | Immunity | Hepatitis | Embryogenesis | Sinus | Mononucleosis | Measles | Varicella | Bacteria | Meningitis | Genetics | Mumps | Hepatitis B virus | Children | Rheumatic fever | Antigens | Health risks | Pharynx | Loci | Fever | Embryonic growth stage | Warts | Herpes labialis | Tuberculosis | Infectious diseases | Ear | Histocompatibility antigen HLA | Gene mapping | Hepatitis A | Hepatitis B | Index Medicus
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2. Full Text The pathogenic T387A missense mutation in the gene encoding signal transducer and activator of transcription 1 exhibits a differential gene expression profile
by Staab, Julia and Schwämmle, Till and Meyer, Thomas
Molecular immunology, ISSN 0161-5890, 12/2020, Volume 128, pp. 79 - 88
Signal transducer and activator of transcription 1 (STAT1) | Chronic mucocutaneous candidiasis (CMC) | Gene expression | Gain-of-function (GOF) mutation | Transcriptional Activation - genetics | Gene Expression Regulation - genetics | Candidiasis, Chronic Mucocutaneous - genetics | Humans | Gain of Function Mutation - genetics | Signal Transduction - genetics | Transcriptome - genetics | STAT1 Transcription Factor - genetics | Protein Domains - genetics | Mutation, Missense - genetics | Phenotype | Cell Line, Tumor | Immunologic Deficiency Syndromes - genetics | Heterozygote | HeLa Cells | Transcription, Genetic - genetics | Cytokines - genetics | Tyrosine | Gene mutations | Molecular genetics | Physiological aspects | Genetic research | Mycoses | Exhibitions | Genetic aspects | Interferon | Genetic transcription | Biological response modifiers | DNA-ligand interactions | Index Medicus
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3. Full Text Severe infectious diseases of childhood as monogenic inborn errors of immunity
by Jean-Laurent Casanova
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2015, Volume 112, Issue 51, pp. E7128 - E7137
Pediatrics | Immunology | Infectious diseases | Human genetics | Primary immunodeficiency | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Encephalitis, Herpes Simplex - immunology | Humans | Genetic Diseases, Inborn - genetics | Lymphoproliferative Disorders - immunology | Mycobacterium Infections - immunology | Young Adult | Pneumococcal Infections - immunology | Mycobacterium Infections - genetics | Pneumococcal Infections - genetics | Complement System Proteins - genetics | Encephalitis, Herpes Simplex - genetics | Epidermodysplasia Verruciformis - immunology | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Child | Genetic Predisposition to Disease | Neisseria - immunology | Tinea - immunology | Infection - immunology | Candidiasis, Chronic Mucocutaneous - genetics | Malaria - immunology | Candidiasis, Chronic Mucocutaneous - immunology | Genetic Diseases, Inborn - immunology | Tinea - genetics | Epidermodysplasia Verruciformis - genetics | Lymphoproliferative Disorders - genetics | Infection - genetics | Models, Immunological | Neisseria - pathogenicity | Influenza, Human - genetics | Interferon-gamma - immunology | Adolescent | Immunologic Deficiency Syndromes - genetics | Models, Genetic | Malaria - genetics | Influenza, Human - immunology | Development and progression | Genetic aspects | Disease susceptibility | Immune response | Communicable diseases | Genotype & phenotype | Genetics | Index Medicus | Biological Sciences | human genetics | PNAS Plus | infectious diseases | pediatrics | primary immunodeficiency | immunology
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4. Full Text MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation
by Garg, Abhishek V and Amatya, Nilesh and Chen, Kong and Cruz, J. Agustin and Grover, Prerna and Whibley, Natasha and Conti, Heather R and Hernandez Mir, Gerard and Sirakova, Tatiana and Childs, Erin C and Smithgall, Thomas E and Biswas, Partha S and Kolls, Jay K and McGeachy, Mandy J and Kolattukudy, Pappachan E and Gaffen, Sarah L
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 475 - 487
negative regulation | Regnase-1 | fungal immunity | autoimmunity | signal transduction | IL-17 | Autoimmunity | Signal transduction | Fungal immunity | Negative regulation | Life Sciences & Biomedicine | Immunology | Science & Technology | Candidiasis - genetics | Oncogene Proteins - genetics | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Immunoblotting | Male | Receptors, Interleukin-17 - genetics | Ribonucleases - metabolism | Host-Pathogen Interactions - immunology | Inflammation - metabolism | Lipocalins - genetics | Adaptor Proteins, Signal Transducing - immunology | Pneumonia - immunology | Candida albicans - physiology | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Interleukin-17 - metabolism | Interleukin-6 - metabolism | Pneumonia - genetics | Interleukin-6 - genetics | Oncogene Proteins - metabolism | Signal Transduction - genetics | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Interleukin-17 - metabolism | Lipocalin-2 | Lipocalins - immunology | Interleukin-6 - immunology | Pneumonia - metabolism | Ribonucleases - genetics | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Acute-Phase Proteins - genetics | Candidiasis - microbiology | Signal Transduction - immunology | HEK293 Cells | Female | Candidiasis - immunology | Nuclear Proteins - genetics | Oncogene Proteins - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Inflammation - immunology | Nuclear Proteins - immunology | Animals | Ribonucleases - immunology | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Adaptor Proteins, Signal Transducing - metabolism | Acute-Phase Proteins - immunology | Medical colleges | Nucleases | Interleukins | RNA | Cellular signal transduction | Inflammation | Proteins | Cytokines | Rodents | Fibroblasts | Infections | Kinases | Laboratory animals | Gene expression | Experiments | Index Medicus
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5. Full Text Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity
by Bustamante, Jacinta and Boisson-Dupuis, Stéphanie and Abel, Laurent and Casanova, Jean-Laurent
Seminars in immunology, ISSN 1044-5323, 2014, Volume 26, Issue 6, pp. 454 - 470
Allergy and Immunology | IFN-γ | Tuberculosis | BCG | ISG15 | Mycobacteriosis | IL-12 | Primary immunodeficiency | Life Sciences & Biomedicine | Immunology | Science & Technology | Candidiasis - genetics | Tuberculosis, Pulmonary - microbiology | Coinfection | Metabolism, Inborn Errors - microbiology | Humans | Salmonella Infections - genetics | Immunity, Innate - genetics | Mycobacterium tuberculosis - immunology | Salmonella Infections - immunology | Candidiasis - microbiology | Tuberculosis, Pulmonary - genetics | Host-Pathogen Interactions - immunology | Interferon-gamma - genetics | Candidiasis - immunology | Candidiasis - pathology | Severity of Illness Index | Salmonella Infections - pathology | Genetic Predisposition to Disease | Genotype | Tuberculosis, Pulmonary - pathology | Metabolism, Inborn Errors - genetics | Genetic Heterogeneity | Metabolism, Inborn Errors - immunology | Phenotype | Tuberculosis, Pulmonary - immunology | Host-Pathogen Interactions - genetics | Interferon-gamma - immunology | Salmonella Infections - microbiology | Metabolism, Inborn Errors - pathology | Index Medicus | tuberculosis | primary immunodeficiency | mycobacteriosis
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