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PLoS medicine, ISSN 1549-1676, 06/2006, Volume 3, Issue 7, pp. e289 - 1164
Background: The autoimmune regulator (AIRE) gene influences thymic self-tolerance induction. In autoimmune polyendocrinopathy syndrome type 1 (APS1; OMIM... 
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antibody Specificity | Polyendocrinopathies, Autoimmune - diagnosis | Alopecia - immunology | Autoantibodies - blood | Dendritic Cells - immunology | Humans | Middle Aged | Child, Preschool | Male | Interferon Type I - immunology | Interferons - immunology | Lymphocyte Subsets - immunology | Palatine Tonsil - immunology | Autoimmunity - immunology | Polyendocrinopathies, Autoimmune - genetics | Thymoma - immunology | HLA Antigens - immunology | Genotype | Polyendocrinopathies, Autoimmune - immunology | Lymphoid Tissue - pathology | Thymus Gland - ultrastructure | Norway - epidemiology | Adolescent | Cell Line, Tumor | Candidiasis, Chronic Mucocutaneous - etiology | Interferons - physiology | Finland - epidemiology | Self Tolerance - immunology | Transcription Factors - deficiency | Alopecia - etiology | Neutralization Tests | Keratoconjunctivitis - immunology | Keratoconjunctivitis - etiology | Myasthenia Gravis - etiology | Lymphoid Tissue - immunology | Thymus Neoplasms - immunology | Antigen Presentation | Immunoglobulin G - immunology | Self Tolerance - genetics | Interleukins - immunology | Adult | Female | Candidiasis, Chronic Mucocutaneous - immunology | Transcription Factors - genetics | Polyendocrinopathies, Autoimmune - epidemiology | Interferon-alpha - immunology | Thymus Neoplasms - complications | Autoantibodies - immunology | Interferons - classification | Thymus Gland - immunology | Myasthenia Gravis - immunology | Thymoma - complications | Development and progression | Genetic aspects | Research | Autoimmune diseases | Index Medicus | Allergy | Immunology | Gene Therapy | Genomics | Autoimmune Diseases | Genetics | Immunology and Allergy
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 475 - 487
Interleukin-17 (IL-17) induces pathology in autoimmunity and infections; therefore, constraint of this pathway is an essential component of its regulation. We... 
negative regulation | Regnase-1 | fungal immunity | autoimmunity | signal transduction | IL-17 | Autoimmunity | Signal transduction | Fungal immunity | Negative regulation | Life Sciences & Biomedicine | Immunology | Science & Technology | Candidiasis - genetics | Oncogene Proteins - genetics | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Immunoblotting | Male | Receptors, Interleukin-17 - genetics | Ribonucleases - metabolism | Host-Pathogen Interactions - immunology | Inflammation - metabolism | Lipocalins - genetics | Adaptor Proteins, Signal Transducing - immunology | Pneumonia - immunology | Candida albicans - physiology | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Interleukin-17 - metabolism | Interleukin-6 - metabolism | Pneumonia - genetics | Interleukin-6 - genetics | Oncogene Proteins - metabolism | Signal Transduction - genetics | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Interleukin-17 - metabolism | Lipocalin-2 | Lipocalins - immunology | Interleukin-6 - immunology | Pneumonia - metabolism | Ribonucleases - genetics | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Acute-Phase Proteins - genetics | Candidiasis - microbiology | Signal Transduction - immunology | HEK293 Cells | Female | Candidiasis - immunology | Nuclear Proteins - genetics | Oncogene Proteins - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Inflammation - immunology | Nuclear Proteins - immunology | Animals | Ribonucleases - immunology | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Adaptor Proteins, Signal Transducing - metabolism | Acute-Phase Proteins - immunology | Medical colleges | Nucleases | Interleukins | RNA | Cellular signal transduction | Inflammation | Proteins | Cytokines | Rodents | Fibroblasts | Infections | Kinases | Laboratory animals | Gene expression | Experiments | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, pp. e0121776 - e0121776
Objective The protein Hwp1, expressed on the pathogenic phase of Candida albicans, presents sequence analogy with the gluten protein gliadin and is also a... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Middle Aged | Fluorescence | Immunoblotting | Male | Candidiasis - microbiology | Young Adult | Candidiasis - blood | Celiac Disease - microbiology | Antibodies, Fungal - isolation & purification | Fungal Proteins - immunology | Immunity, Humoral | Celiac Disease - immunology | Celiac Disease - blood | Celiac Disease - complications | Adult | Candida albicans - physiology | Female | Candidiasis - immunology | Enzyme-Linked Immunosorbent Assay | Gliadin - immunology | Electrophoresis, Polyacrylamide Gel | Peptides - immunology | Biomarkers - blood | Antibodies, Fungal - immunology | Cross Reactions - immunology | Candidiasis - complications | Adolescent | Aged | Infection | Celiac disease | Peptides | Analysis | Immunoglobulin G | Immunoglobulin A | Health aspects | Gluten | Cereals | Disease | Antibodies | Homeostasis | Alcohol | Infections | Small intestine | Immunity | Proteins | Analogs | Gliadin | Immunity (humoral) | Nosocomial infections | microchips | Antigens | Immunoglobulins | Dendritic cells | Cross-reactivity | Patients | Substrates | Hypotheses | Reactivity | Autoimmune diseases | Index Medicus | Candidiasis/microbiology | Celiac Disease/complications | Antibodies, Fungal/immunology | Gliadin/immunology | Celiac Disease/immunology | Antibodies, Fungal/isolation & purification | Life Sciences | Celiac Disease/microbiology | Biomarkers/blood | Candidiasis/complications | Candida albicans/physiology | Candidiasis/immunology | Mycology | Cross Reactions/immunology | Microbiology and Parasitology | Celiac Disease/blood | Fungal Proteins/immunology | Candidiasis/blood | Peptides/immunology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2015, Volume 112, Issue 51, pp. E7128 - E7137
This paper reviews the developments that have occurred in the field of human genetics of infectious diseases from the second half of the 20th century onward.... 
Pediatrics | Immunology | Infectious diseases | Human genetics | Primary immunodeficiency | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Encephalitis, Herpes Simplex - immunology | Humans | Genetic Diseases, Inborn - genetics | Lymphoproliferative Disorders - immunology | Mycobacterium Infections - immunology | Young Adult | Pneumococcal Infections - immunology | Mycobacterium Infections - genetics | Pneumococcal Infections - genetics | Complement System Proteins - genetics | Encephalitis, Herpes Simplex - genetics | Epidermodysplasia Verruciformis - immunology | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Child | Genetic Predisposition to Disease | Neisseria - immunology | Tinea - immunology | Infection - immunology | Candidiasis, Chronic Mucocutaneous - genetics | Malaria - immunology | Candidiasis, Chronic Mucocutaneous - immunology | Genetic Diseases, Inborn - immunology | Tinea - genetics | Epidermodysplasia Verruciformis - genetics | Lymphoproliferative Disorders - genetics | Infection - genetics | Models, Immunological | Neisseria - pathogenicity | Influenza, Human - genetics | Interferon-gamma - immunology | Adolescent | Immunologic Deficiency Syndromes - genetics | Models, Genetic | Malaria - genetics | Influenza, Human - immunology | Development and progression | Genetic aspects | Disease susceptibility | Immune response | Communicable diseases | Index Medicus | Biological Sciences | human genetics | PNAS Plus | infectious diseases | pediatrics | primary immunodeficiency | immunology
Journal Article
The Journal of experimental medicine, ISSN 1540-9538, 06/2014, Volume 211, Issue 6, pp. 1197 - 1213
Competition for iron influences host–pathogen interactions. Pathogens secrete small iron-binding moieties, siderophores, to acquire host iron. In response, the... 
Immunology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Candidiasis - genetics | Oncogene Proteins - genetics | Gentisates - metabolism | Immunity, Innate - genetics | Immunoblotting | Male | Bacterial Infections - genetics | RNA Interference | Lipocalins - genetics | Candida albicans - physiology | Transcription Factors - immunology | Carrier Proteins - immunology | Enterobactin - metabolism | Bacterial Outer Membrane Proteins - immunology | Hydroxybutyrate Dehydrogenase - immunology | Oncogene Proteins - metabolism | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Cell Surface - immunology | Mice, Knockout | Gentisates - immunology | Bacterial Outer Membrane Proteins - metabolism | Escherichia coli - genetics | Lipocalin-2 | Lipocalins - immunology | Staphylococcus aureus - immunology | Mice | Bacterial Infections - metabolism | Positive Regulatory Domain I-Binding Factor 1 | Receptors, Cell Surface - genetics | Staphylococcus aureus - physiology | Acute-Phase Proteins - genetics | Mutation - immunology | Hydroxybutyrate Dehydrogenase - genetics | Bacterial Infections - immunology | Female | Candidiasis - immunology | Escherichia coli - physiology | Oncogene Proteins - immunology | Bacterial Outer Membrane Proteins - genetics | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Siderophores - metabolism | Mice, Inbred C57BL | Kaplan-Meier Estimate | Escherichia coli - immunology | Receptors, Cell Surface - metabolism | Transcription Factors - genetics | Hydroxybutyrate Dehydrogenase - metabolism | Transcription Factors - metabolism | Candidiasis - metabolism | Carrier Proteins - genetics | Immunity, Innate - immunology | Enterobactin - immunology | Animals | Carrier Proteins - metabolism | Siderophores - immunology | Acute-Phase Proteins - immunology | Index Medicus
Journal Article