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Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2016, Volume 59, Issue 17, pp. 7840 - 7855
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2010, Volume 20, Issue 9, pp. 2770 - 2775
Compound showed >∼840-fold CB /CB subtype selectivity whereas was only 31-fold selective. The cannabinoid CB /CB receptor subtype selectivity in the... 
Metasite | Polar surface area | Rimonabant | Cannabinoid CB1 receptor | Site of metabolism prediction | P-Glycoprotein | Subtype selectivity | Lipophilicity
Journal Article
Neuroscience, ISSN 0306-4522, 2012, Volume 227, pp. 313 - 326
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2014, Volume 452, Issue 3, pp. 334 - 339
We performed molecular modeling and docking to predict a putative binding pocket and associated ligand–receptor interactions for human cannabinoid receptor 2... 
Cannabinoid receptor subtype 2 (CB2) | Cyclic adenosine monophosphate (cAMP) | Time-resolved fluorescence resonance energy (TR-FRET) transfer | Molecular modeling | Site-directed mutagenesis | Adenylyl cyclase (AC activity) | SR 144528 | HUMAN BREAST | ANTAGONIST | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSMEMBRANE DOMAIN | FUNCTIONAL-ROLE | CANNABINOID RECEPTOR | BIOPHYSICS | PROTEIN-COUPLED RECEPTOR | BINDING-SITE | CANCER-CELL-PROLIFERATION | Cannabinoid Receptor Agonists - metabolism | Bornanes - chemistry | Cricetulus | Receptor, Cannabinoid, CB2 - agonists | Humans | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Cannabinoid Receptor Agonists - chemistry | Receptor, Cannabinoid, CB2 - genetics | Valine - chemistry | Pyrazoles - chemistry | Cyclic AMP - chemistry | Cyclohexanols - metabolism | Cyclohexanols - chemistry | Escherichia coli - metabolism | Receptor, Cannabinoid, CB2 - chemistry | Binding Sites | Cyclic AMP - metabolism | Leucine - genetics | CHO Cells | Recombinant Proteins - metabolism | Mutagenesis, Site-Directed | Signal Transduction | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Pyrazoles - metabolism | Molecular Dynamics Simulation | Leucine - chemistry | Animals | Bornanes - metabolism | Cannabinoid Receptor Antagonists - metabolism | Escherichia coli - genetics | Cannabinoid Receptor Antagonists - chemistry | Hydrophobic and Hydrophilic Interactions | Protein Binding | Ligands | Valine - genetics | Molecular Docking Simulation | site-directed mutagenesis | adenylyl cyclase (AC activity) | cannabinoid receptor subtype 2 (CB2) | time-resolved fluorescence resonance energy (TR-FRET) transfer
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 05/2016, Volume 137, Issue 4, pp. 618 - 629
Journal Article
Journal Article
Journal Article