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Brain, Behavior, and Immunity, ISSN 0889-1591, 2015, Volume 51, pp. 204 - 211
Highlights • Endocannabinoids participate in the fever induced by TNF, IL-1β, IL-6, CRF and ET-1. • Endocannabinoids are not involved in the fever induced by... 
Psychiatry | Allergy and Immunology | Prostaglandins | Cytokines | β-Endorphin | Fever | Endocannabinoids | Anandamide | SYSTEM | ENDOGENOUS CANNABINOIDS | RECEPTOR-SELECTIVE ANTAGONIST | RATS | IMMUNOLOGY | NEUROSCIENCES | beta-Endorphin | ENDOTHELIAL-CELLS | INDEPENDENT FEVER | ANXIETY-LIKE | CANNABINOID 1 RECEPTORS | CB1 RECEPTORS | Narcotic Antagonists - administration & dosage | Rats, Wistar | Body Temperature - drug effects | Male | Fever - chemically induced | Cytokines - physiology | Fever - physiopathology | Receptor, Cannabinoid, CB1 - physiology | Endocannabinoids - physiology | Arachidonic Acids - administration & dosage | Interleukin-6 - physiology | Corticotropin-Releasing Hormone - administration & dosage | Interleukin-6 - administration & dosage | Arachidonic Acids - physiology | Interleukin-1beta - physiology | Piperidines - administration & dosage | beta-Endorphin - cerebrospinal fluid | Endothelin-1 - administration & dosage | Rats | Cytokines - administration & dosage | Polyunsaturated Alkamides - administration & dosage | Prostaglandins - physiology | Pyrazoles - administration & dosage | Animals | Endocannabinoids - administration & dosage | Interleukin-1beta - administration & dosage | Tumor Necrosis Factor-alpha - physiology | Tumor Necrosis Factor-alpha - administration & dosage | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Naloxone - administration & dosage | Prostaglandins - administration & dosage
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 11/2018, Volume 28, Issue 11, pp. 1247 - 1259
Endocannabinoids and their receptors not only contribute to the control of natural processes of appetite regulation and energy balance but also have an... 
Appetite regulation | Gamma-aminobutyric acid | Cannabinoids | CB1 | Serotonin | Paraventricular hypothalamic nucleus | POMC NEURONS | ENDOGENOUS CANNABINOIDS | HYPERPHAGIA | PSYCHIATRY | ENDOCANNABINOID SYSTEM | NEUROSCIENCES | CLINICAL NEUROLOGY | NEUROPEPTIDE-Y | BODY-WEIGHT | OBESITY | CANNABINOID RECEPTOR | INHIBITION | PHARMACOLOGY & PHARMACY | AUTORADIOGRAPHY | Piperazines - administration & dosage | Cyproheptadine - administration & dosage | Serotonin - administration & dosage | Serotonin Antagonists - administration & dosage | Receptors, Serotonin, 5-HT1 - physiology | gamma-Aminobutyric Acid - metabolism | Amphetamines - pharmacology | Spiro Compounds - administration & dosage | Male | Amphetamines - administration & dosage | Serotonin - pharmacology | Receptor, Cannabinoid, CB1 - physiology | Eating - physiology | Serotonin Receptor Agonists - pharmacology | Cyproheptadine - pharmacology | Drug Interactions | Receptor, Cannabinoid, CB1 - agonists | Tritium - metabolism | Piperidines - pharmacology | Pyrroles - administration & dosage | Pyrazoles - pharmacology | Piperidines - administration & dosage | Pyridines - administration & dosage | Microinjections | Rats | 8-Hydroxy-2-(di-n-propylamino)tetralin - pharmacology | Piperidones - pharmacology | Serotonin Antagonists - pharmacology | Piperazines - pharmacology | Arachidonic Acids - pharmacology | Piperidones - administration & dosage | Pyrazoles - administration & dosage | Pyrroles - pharmacology | 8-Hydroxy-2-(di-n-propylamino)tetralin - administration & dosage | Animals | Serotonin - metabolism | Paraventricular Hypothalamic Nucleus - metabolism | Pyridines - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Serotonin Receptor Agonists - administration & dosage | Spiro Compounds - pharmacology | GABA | Control systems | RNA | Neurophysiology
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 11/2017, Volume 109, pp. 21 - 30
The lipophilic phytocannabinoids cannabidiol (CBD) and Δ -tetrahydrocannabinol (THC) show therapeutic efficacy in various medical conditions. Both molecules... 
Cannabinoids | Oral bioavailability | Piperine | SNEDDS | First pass effect | RESVERATROL | CURCUMIN | P-GLYCOPROTEIN | UDP-GLUCURONOSYLTRANSFERASE | IN-VITRO | LIPID-BASED FORMULATIONS | METABOLISM | PHARMACOKINETICS | ENZYMES | PHARMACOLOGY & PHARMACY | Polyunsaturated Alkamides - chemistry | Emulsions | Stilbenes - administration & dosage | Cannabidiol - administration & dosage | Excipients - pharmacokinetics | Nanoparticles - chemistry | Rats, Wistar | Alkaloids - pharmacokinetics | Curcumin - chemistry | Biological Availability | Male | Stilbenes - chemistry | Benzodioxoles - administration & dosage | Curcumin - administration & dosage | Drug Delivery Systems | Lipids - chemistry | Excipients - chemistry | Benzodioxoles - pharmacokinetics | Piperidines - pharmacokinetics | Benzodioxoles - chemistry | Cannabidiol - pharmacokinetics | Cannabidiol - chemistry | Piperidines - administration & dosage | Piperidines - chemistry | Gastrointestinal Absorption | Administration, Oral | Curcumin - pharmacokinetics | Lipids - administration & dosage | Dronabinol - pharmacokinetics | Excipients - administration & dosage | Polyunsaturated Alkamides - administration & dosage | Animals | Lipids - pharmacokinetics | Stilbenes - pharmacokinetics | Alkaloids - administration & dosage | Nanoparticles - administration & dosage | Polyunsaturated Alkamides - pharmacokinetics | Dronabinol - administration & dosage | Dronabinol - chemistry | Alkaloids - chemistry
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2015, Volume 112, Issue 45, pp. 14084 - 14089
Marijuana exerts profound effects on human social behavior, but the neural substrates underlying such effects are unknown. Here we report that social contact... 
reward | endocannabinoid | oxytocin | ACTIVATION | HUMAN BRAIN | ANXIETY | social behavior | BEHAVIOR | MULTIDISCIPLINARY SCIENCES | MARIHUANA | SYNAPTIC PLASTICITY | NUCLEUS-ACCUMBENS | CANNABINOID RECEPTORS | MICE | anandamide | Endocannabinoids - metabolism | Immunohistochemistry | Piperazines - administration & dosage | Bornanes - administration & dosage | Clozapine - administration & dosage | Nucleus Accumbens - metabolism | Bornanes - pharmacology | Male | Carbamates - administration & dosage | Oxytocin - metabolism | Receptors, Cannabinoid - metabolism | Arachidonic Acids - metabolism | Benzamides - administration & dosage | Clozapine - pharmacology | Piperidines - pharmacology | Social Behavior | Benzamides - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Piperidines - administration & dosage | Benzodiazepines - pharmacology | Mice, Inbred C57BL | Clozapine - analogs & derivatives | Polyunsaturated Alkamides - metabolism | Piperazines - pharmacology | Cocaine - administration & dosage | Cocaine - pharmacology | Pyrazoles - administration & dosage | Animals | Analysis of Variance | Benzodiazepines - administration & dosage | Signal Transduction - physiology | Mice | Lipids - analysis | Reward | Infusions, Intraventricular | Autism Spectrum Disorder - physiopathology | Influence | Cellular signal transduction | Research | Oxytocin | Analysis | Endocannabinoids | Biological Sciences
Journal Article
Neurobiology of Learning and Memory, ISSN 1074-7427, 10/2016, Volume 134, pp. 264 - 274
The cannabinoid system plays an important role in memory processes, many studies have indicated that cannabinoid receptor ligands have ability to modulate... 
Hemopressin | (m)VD-hemopressin(α) | Recognition memory | (m)RVD-hemopressin(α) | Alzheimer’s disease | Cannabinoid receptor | Alzheimer's disease | Amyloid beta-Peptides - pharmacology | Male | Peptide Fragments - pharmacology | Cannabinoid Receptor Agonists - pharmacology | Hemoglobins - administration & dosage | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Cannabinoid Receptor Antagonists - pharmacology | Behavior, Animal - drug effects | Amyloid beta-Peptides - administration & dosage | Hemoglobins - pharmacology | Alzheimer Disease - chemically induced | Disease Models, Animal | Pyrazoles - pharmacology | Piperidines - administration & dosage | Benzoxazines - administration & dosage | Morpholines - administration & dosage | Peptide Fragments - administration & dosage | Alzheimer Disease - drug therapy | Morpholines - pharmacology | Cannabinoid Receptor Agonists - administration & dosage | Naphthalenes - pharmacology | Pyrazoles - administration & dosage | Animals | Memory Disorders - drug therapy | Recognition (Psychology) - drug effects | Naphthalenes - administration & dosage | Benzoxazines - pharmacology | Cannabinoid Receptor Antagonists - administration & dosage | Mice | Oligopeptides - administration & dosage | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Infusions, Intraventricular | Oligopeptides - pharmacology | Memory Disorders - chemically induced
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 02/2014, Volume 348, Issue 2, pp. 316 - 323
The cannabinoid system has been demonstrated to modulate the acute and chronic pain of multiple origins. Mouse VD-hemopressin (alpha) [(m)VD-Hp alpha], an... 
CB1 | PAIN | MODELS | ENDOCANNABINOID SYSTEM | RATS | PHARMACOLOGY & PHARMACY | MICE | MECHANISMS | BLOCKADE | ANALGESIA | Central Nervous System - metabolism | Male | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Cannabinoid Receptor Agonists - chemistry | Oligopeptides - adverse effects | Oligopeptides - therapeutic use | Hemoglobins - administration & dosage | Hemoglobins - adverse effects | Receptor, Cannabinoid, CB1 - agonists | Cannabinoid Receptor Agonists - adverse effects | Cannabinoid Receptor Agonists - therapeutic use | Cannabinoid Receptor Antagonists - pharmacology | Behavior, Animal - drug effects | Body Temperature Regulation - drug effects | Neurons - metabolism | Neurons - drug effects | Oligopeptides - chemistry | Hemoglobins - therapeutic use | Analgesics - adverse effects | Receptors, Opioid - metabolism | Injections, Spinal | Analgesics - therapeutic use | Nerve Tissue Proteins - antagonists & inhibitors | Nerve Tissue Proteins - agonists | Peptide Fragments - administration & dosage | Analgesics - administration & dosage | Appetite Regulation - drug effects | Cannabinoid Receptor Antagonists - adverse effects | Mice, Inbred Strains | Cannabinoid Receptor Agonists - administration & dosage | Nerve Tissue Proteins - metabolism | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Hemoglobins - chemistry | Peptide Fragments - chemistry | Animals | Analgesics - antagonists & inhibitors | Narcotic Antagonists - pharmacology | Central Nervous System - drug effects | Mice | Oligopeptides - administration & dosage | Peptide Fragments - adverse effects | Peptide Fragments - therapeutic use | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Infusions, Intraventricular
Journal Article
Journal of Neuroinflammation, ISSN 1742-2094, 01/2012, Volume 9, Issue 1, pp. 8 - 8
Background: Alzheimer's disease (AD) brain shows an ongoing inflammatory condition and non-steroidal anti-inflammatories diminish the risk of suffering the... 
Interleukin 6 | Cannabinoids | Glial activation | Anti-inflammatories | β-amyloid peptide | Tumor necrosis factor-α | Alzheimer's disease | ACTIVATION | CANNABIDIOL | ALZHEIMERS-DISEASE | MEMORY DEFICITS | beta-amyloid peptide | ENDOCANNABINOID SYSTEM | PATHOLOGY | IMMUNOLOGY | anti-inflammatories | NEUROSCIENCES | tumor necrosis factor-alpha | interleukin 6 | glial activation | IN-VIVO | PROTEIN EXPRESSION | cannabinoids | CENTRAL-NERVOUS-SYSTEM | RECEPTOR AGONIST | Encephalitis - prevention & control | Alzheimer Disease - complications | Cognition Disorders - diagnostic imaging | Encephalitis - diagnostic imaging | Humans | Choroid Plexus - metabolism | Fluorodeoxyglucose F18 - metabolism | Glycogen Synthase Kinase 3 beta | Positron-Emission Tomography | RNA, Messenger - metabolism | Corpus Striatum - metabolism | Cognition Disorders - prevention & control | Time Factors | Cyclooxygenase 2 - genetics | Cognition Disorders - etiology | Amyloid beta-Peptides - metabolism | Microglia - pathology | Disease Models, Animal | Benzoxazines - administration & dosage | Enzyme-Linked Immunosorbent Assay | Microglia - drug effects | Administration, Oral | Cannabinoids - administration & dosage | Choroid Plexus - pathology | Gene Expression Regulation - genetics | Morpholines - administration & dosage | Mice, Transgenic | Glycogen Synthase Kinase 3 - metabolism | Gene Expression Regulation - drug effects | Receptor, Cannabinoid, CB2 - metabolism | Amyloid beta-Protein Precursor - genetics | Animals | Analysis of Variance | Naphthalenes - administration & dosage | Cyclooxygenase 2 - metabolism | Corpus Striatum - drug effects | Mice | Alzheimer Disease - genetics | Encephalitis - etiology | tumor necrosis factor-α
Journal Article