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Nature Communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, p. 6220
The tumour microenvironment contributes to cancer metastasis and drug resistance. However, most high throughput screening (HTS) assays for drug discovery use... 
OVARIAN-CANCER METASTASIS | PLATFORM | INVASION | MICROENVIRONMENT | MULTIDISCIPLINARY SCIENCES | BIOLOGY | FIBROBLASTS | PROGRESSION | MESOTHELIAL CELLS | SPHEROID MODEL | STEPS | Biguanides - pharmacology | Epithelial Cells - metabolism | Escin - chemistry | High-Throughput Screening Assays - instrumentation | Coculture Techniques | Epithelial Cells - drug effects | Humans | Ovarian Neoplasms - pathology | Extracellular Matrix - metabolism | Prochlorperazine - chemistry | Tomatine - chemistry | Tomatine - pharmacology | Isoquinolines - chemistry | Isoquinolines - pharmacology | Benzophenanthridines - chemistry | Escin - pharmacology | Inhibitory Concentration 50 | Female | Antineoplastic Agents - pharmacology | Ovarian Neoplasms - metabolism | Ovarian Neoplasms - drug therapy | Fibroblasts - metabolism | High-Throughput Screening Assays - methods | Tumor Microenvironment - drug effects | Prochlorperazine - pharmacology | Cantharidin - pharmacology | Extracellular Matrix - drug effects | Cantharidin - chemistry | Epithelial Cells - pathology | Biguanides - chemistry | Antineoplastic Agents - chemistry | Cell Adhesion - drug effects | Fibroblasts - pathology | Benzophenanthridines - pharmacology | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Animals | Mice, Nude | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | Primary Cell Culture
Journal Article
PLoS ONE, ISSN 1932-6203, 2010, Volume 5, Issue 11, p. e15460
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 07/2000, Volume 274, Issue 1, pp. 157 - 165
A novel rice acidic pathogenesis-related (PR) class 1 cDNA (OsPR1a) was isolated from jasmonic acid (JA)-treated rice seedling leaf. The OsPR1a cDNA is 830 bp... 
phosphorylation/dephosphorylation | rice | OsPR1a | protein phosphatase inhibitors | phytohormones | Phytohormones | Phosphorylation/dephosphorylation | Protein phosphatase inhibitors | Rice | BIOCHEMISTRY & MOLECULAR BIOLOGY | ACQUIRED-RESISTANCE | ETHYLENE SIGNAL | PHYTOALEXIN PRODUCTION | BIOPHYSICS | SALICYLIC-ACID | INDUCED RESISTANCE | BIOSYNTHESIS | PLANTS | ARABIDOPSIS | JASMONIC ACID | PATHOGENESIS-RELATED PROTEINS | Transcription, Genetic - drug effects | Multigene Family | Oryza - metabolism | Molecular Sequence Data | Dicarboxylic Acids - pharmacology | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Salicylic Acid - pharmacology | Oryza - genetics | Time Factors | Base Sequence | Light | Cloning, Molecular | Plant Proteins - metabolism | Phosphorylation - drug effects | Protein Synthesis Inhibitors - pharmacology | Ethylenes - pharmacology | Amino Acid Sequence | Cantharidin - pharmacology | Gene Library | Down-Regulation | Enzyme Inhibitors - pharmacology | Sequence Analysis, DNA | Cycloheximide - pharmacology | Keratolytic Agents - pharmacology | Sequence Homology, Amino Acid | Abscisic Acid - pharmacology | Plant Proteins - genetics | Gene Expression Regulation, Plant - drug effects | Indoleacetic Acids - pharmacology | Gibberellins - pharmacology | DNA, Complementary - metabolism | Plant Growth Regulators - pharmacology | Staurosporine - pharmacology | Hydrogen-Ion Concentration | cycloheximide | OsPR1a gene | staurosporine | endothall | Phytohormone JA | salicylic acid | PR1 gene | Cut protein | acidic pathogenesis-related protein | 3-indoleacetic acid | cantharidin
Journal Article
Planta, ISSN 0032-0935, 4/2008, Volume 227, Issue 5, pp. 981 - 990
We report isolation and transcriptional profiling of rice (Oryza sativa L.) mitogen-activated protein kinase (MAPK), OsSIPK (salicylic acid-induced protein... 
Messenger RNA | Genes | Genomics | Epidermal cells | Genomes | Gene expression regulation | Plants | Drought | Rice | Seedlings | Life Sciences | Salicylic acid | Multiple stress responsive | Rhythmic expression | Forestry | Ecology | Agriculture | Plant Sciences | Defense/stress response | Jasmonic acid | SMALL GTPASE OSRAC1 | ARABIDOPSIS-THALIANA | DRAFT SEQUENCE | ACTIVATED PROTEIN-KINASE | salicylic acid | multiple stress responsive | PLANT SCIENCES | SIGNAL-TRANSDUCTION | rhythmic expression | ORYZA-SATIVA | stress response | ENVIRONMENTAL-STRESSES | SALICYLIC-ACID | defense | GENE-EXPRESSION | jasmonic acid | DISEASE RESISTANCE | Gene Expression Regulation, Enzymologic - drug effects | Okadaic Acid - pharmacology | Seedlings - genetics | Gene Expression Profiling | Seedlings - enzymology | Salicylic Acid - pharmacology | Sulfur Dioxide - pharmacology | Cell Nucleus - metabolism | Ultraviolet Rays | Oryza - genetics | Chitosan - pharmacology | Organophosphorus Compounds - pharmacology | Plant Leaves - enzymology | Gene Expression Regulation, Plant - radiation effects | Cantharidin - pharmacology | Gene Expression Regulation, Enzymologic - radiation effects | RNA, Messenger - genetics | Hydrogen Peroxide - pharmacology | Gene Expression Regulation, Plant - genetics | Cyclopentanes - pharmacology | Oryza - enzymology | Sequence Analysis, DNA | Cycloheximide - pharmacology | Abscisic Acid - pharmacology | Plant Proteins - genetics | Blotting, Northern | Gene Expression Regulation, Plant - drug effects | Plant Leaves - genetics | Oxylipins - pharmacology | Mitogen-Activated Protein Kinases - genetics | Protein kinases
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 11/2016, Volume 513, Issue 1-2, pp. 612 - 627
Journal Article
Journal Article
ChemMedChem, ISSN 1860-7179, 12/2008, Volume 3, Issue 12, pp. 1878 - 1892
Journal Article
International Journal of Cancer, ISSN 0020-7136, 05/2009, Volume 124, Issue 9, pp. 2186 - 2199
To identify an agent with specific activity against leukemic stem cells (LSCs), we evaluated compounds that targeted hepatic leukemia factor (HLF), a gene... 
cantharidin norcantharidin | LSC in vitro model | AML xenograft model | leukemic stem cells | Cantharidin norcantharidin | Leukemic stem cells | INTERNAL TANDEM DUPLICATION | CONSTITUTIVE ACTIVATION | BZIP FACTOR | SELF-RENEWAL | EX-VIVO EXPANSION | ANTICANCER ACTIVITY | PROTEIN PHOSPHATASES | ONCOLOGY | FLT3 GENE | TRANSCRIPTION FACTOR | FACTOR GENE | Basic-Leucine Zipper Transcription Factors - metabolism | Cytarabine - pharmacology | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myeloid, Acute - metabolism | Luminescence | Daunorubicin - pharmacology | Transplantation, Heterologous | STAT5 Transcription Factor - metabolism | Arylamine N-Acetyltransferase - antagonists & inhibitors | Caspases - metabolism | Neoplastic Stem Cells - metabolism | Stromal Cells - drug effects | Leukemia, Myeloid, Acute - drug therapy | Neoplastic Stem Cells - pathology | Antimetabolites, Antineoplastic - pharmacology | Female | Colony-Forming Units Assay | Phosphorylation - drug effects | Snail Family Transcription Factors | Cantharidin - pharmacology | Leukemia, Myeloid, Acute - pathology | Stromal Cells - metabolism | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Survival Rate | Fetal Blood - cytology | Fetal Blood - drug effects | Fetal Blood - metabolism | Mice, SCID | Proto-Oncogene Proteins c-myc - metabolism | Transcription Factors - metabolism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Mice, Inbred NOD | Mice | Cell Cycle - drug effects | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, p. 11391
Journal Article
Journal of Biotechnology, ISSN 0168-1656, 2002, Volume 97, Issue 3, pp. 213 - 221
Journal Article